Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory

Morris water maze: procedures for assessing spatial and related forms of learning and memory

Vorhees, C. V., & Williams, M. T. (2006) · Nature Protocols · doi:10.1038/nprot.2006.116 · Cited by 4,629

Plasticity in gray and white: neuroimaging changes in brain structure during learning

Zatorre, R. J., Fields, R. D., & Johansen-Berg, H. (2012) · Nature Neuroscience · doi:10.1038/nn.3045 · Cited by 1,685

A century of trends in adult human height

NCD Risk Factor Collaboration (NCD-RisC) (2016) · eLife · doi:10.7554/elife.13410 · Cited by 1,558

Motor skill learning requires active central myelination

McKenzie, I. A., Ohayon, D., Li, H., Paes de Faria, J., Emery, B., Tohyama, K., & Richardson, W. D. (2014) · Science · doi:10.1126/science.1254960 · Cited by 1,177

The ageing cortical synapse: hallmarks and implications for cognitive decline

Morrison, J. H., & Baxter, M. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3200 · Cited by 965

Top-down suppression deficit underlies working memory impairment in normal aging

Gazzaley, A., Cooney, J. W., Rissman, J., & D'Esposito, M. (2005) · Nature Neuroscience · doi:10.1038/nn1543 · Cited by 934

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

Young, K. M., Psachoulia, K., Tripathi, R. B., Dunn, S.-J., Cossell, L., Attwell, D., Tohyama, K., & Richardson, W. D. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.006 · Cited by 919

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

Kang, S. H., Fukaya, M., Yang, J. K., Rothstein, J. D., & Bergles, D. E. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.009 · Cited by 815

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

Hughes, E. G., Kang, S. H., Fukaya, M., & Bergles, D. E. (2013) · Nature Neuroscience · doi:10.1038/nn.3390 · Cited by 808

Rejuvenation of Regeneration in the Aging Central Nervous System

Ruckh, J. M., Zhao, J.-W., Shadrach, J. L., van Wijngaarden, P., Rao, T. N., Wagers, A. J., & Franklin, R. J. M. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2011.11.019 · Cited by 649

Oligodendroglia and Myelin: Supporting the Connectome

Niu, J., Verkhratsky, A., Butt, A. M., & Yi, C. (2025) · Advances in neurobiology · doi:10.1007/978-3-031-87919-7_1 · Cited by 7

Impaired macroautophagy in oligodendrocyte precursor cells suppresses neuronal plasticity via a senescence-associated signaling

Chen, H., Sun, Y., Li, Q.-F., Du, Y.-T., Hu, N., Sui, A., Luo, X.-Q., Huang, X., Zhu, C., Yang, G., et al. (2025) · Science Advances · doi:10.1126/sciadv.adq7665 · Cited by 7

Astrocyte States in Brain Aging and Neurodegeneration: At the Crossroads of Senescence and Reactivity

Pacca-Corrêa, J. B. L., Fernandes, B. M., Siqueira, M., Schafbenker, R., Baumart, G. J., Damico, I. V., Gomes, F. C. A., & Matias, I. C. P. (2026) · Neurochemical Research · doi:10.1007/s11064-026-04709-7 · Cited by 6

Maternal gastrointestinal nematode infection alters hippocampal neuroimmunity, promotes synaptic plasticity, and improves resistance to direct infection in offspring

Noel, S. C., Madranges, J. F., Gothié, J. M., Ewald, J., Milnerwood, A. J., Kennedy, T. E., & Scott, M. E. (2024) · Scientific Reports · doi:10.1038/s41598-024-60865-2 · Cited by 7

Myosin superfamily members during myelin formation and regeneration

Yamazaki, R., & Ohno, N. (2024) · Journal of Neurochemistry · doi:10.1111/jnc.16202 · Cited by 6

Preventing production of new oligodendrocytes impairs remyelination and sustains behavioural deficits after demyelination

He, Y., Xu, Z., He, Y., Liu, J., Li, J., Wang, S., & Xiao, L. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150592 · Cited by 5

Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice

Jäntti, H., Oksanen, M., Kettunen, P., Manta, S., Moulédous, L., Koivisto, H., Ruuth, J., Trontti, K., Dhungana, H., Keuters, M. H., et al. (2022) · Cells · doi:10.3390/cells11244116 · Cited by 6

Plasticity in oligodendrocyte lineage progression: An OPC puzzle on our nerves

Craig, G. A., Yoo, S., D'Araujo, T. Y., & Xiao, J. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14845 · Cited by 6

Integrated Multi-Omics Analysis Reveals Immune and Metabolic Dysregulation in a Restraint Stress-Induced Depression Model

Wang, Z., Wang, X., Li, Y., Zhao, Q., Lan, Z., & Li, W. (2025) · Biomedicines · doi:10.3390/biomedicines13092183 · Cited by 5

Microglia-derived APOE2 improves remyelination even in the presence of endogenous APOE4

Nolt, G. L., Golden, L. R., Thorpe, S. P., Funnell, J. L., Stephens, I. O., Hernandez, G., MacLean, S. M., Lucido, C. C., Brock, C. R., Pallerla, A. V., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03639-5 · Cited by 5

Uncovering oligodendrocyte enhancers that control Cnp expression

Fan, C., An, H., Kim, D., & Park, Y. (2023) · Human Molecular Genetics · doi:10.1093/hmg/ddad141 · Cited by 7

Ospemifene, a Selective Estrogen Receptor Modulator, Enhances Oligodendrocyte Myelination and Preserves Neurofunctions Against Injuries

Liu, W., Ren, H. W., Wang, J., Huang, X., Wu, S., Gao, X., Li, T., Zhang, Z., Mei, F., Yu, B., et al. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70235 · Cited by 5

Neuronal Prosurvival Role of Ceramide Synthase 2 by Olidogendrocyte-to-Neuron Extracellular Vesicle Transfer

Casadomé‐Perales, Á., Naya, S., Fernández‐Martínez, E., Mille, B. G., Guerrero‐Valero, M., Peinado, H., Guix, F. X., Dotti, C. G., & Palomer, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065986 · Cited by 5

β-carbolines that enhance GABAA receptor response expressed in oligodendrocytes promote remyelination in an in vivo rat model of focal demyelination

Cisneros-Mejorado, A., Ordaz, R. P., Garay, E., & Arellano, R. O. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1369730 · Cited by 5

Early postnatal whisker deprivation cross-modally modulates prefrontal cortex myelination and leads to social novelty deficit

He, Y., Liu, J., Xiao, H., & Xiao, L. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149136 · Cited by 5

Cognitive function and associated factors among postmenopausal women with hypertension and natural menopause in Taiwan

Chou, C., Chien, L., Lin, M., & Wang, C. (2020) · Geriatric Nursing · doi:10.1016/j.gerinurse.2020.12.007 · Cited by 5

The Larval Zebrafish Vestibular System Is a Promising Model to Understand the Role of Myelin in Neural Circuits

Auer, F., & Schoppik, D. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.904765 · Cited by 6

Mutation of the attractin gene impairs working memory in rats

Liu, M., Xue, C., Li, X., Ding, H., Zhang, M., Chen, K., Li, Y., Gao, S., Xu, X., & Zhang, W. (2023) · Brain and Behavior · doi:10.1002/brb3.2876 · Cited by 5

Oligodendrocytes form paranodal bridges that generate chains of myelin sheaths that are vulnerable to degeneration with agePreprint

Call, C. L., Neely, S. A., Early, J. J., James, O. G., Zoupi, L., Williams, A., Chandran, S., Lyons, D. A., & Bergles, D. E. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.16.480718 · Cited by 5

T cells induce interferon-responsive oligodendrocytes during white matter agingPreprint

Kaya, T., Mattugini, N., Liu, L., Ji, H., Besson‐Girard, S., Kaiji, S., Liesz, A., Gökçe, Ö., & Simons, M. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.26.485917 · Cited by 5

Label-free and fluorescence imaging of oligodendrocytes and myelin

Kamen, Y., Doty, M. E., Ciolkowski, M. E., Bame, X., Pietramale, A. N., Schain, A. J., Grutzendler, J., & Hill, R. (2025) · npj Imaging · doi:10.1038/s44303-025-00098-8 · Cited by 7

Exploiting glial cell functions for neurodegeneration therapy

Olajide, T. S. (2025) · Neuroprotection/Neuroprotection (Chichester, England. Print) · doi:10.1002/nep3.70020 · Cited by 4

Preliminary evaluation of the proteomic profiling in the hippocampus of aged grazing cattle

Cozzolino, F., Canè, L., Sacchettino, L., Gatto, M. C., Iacobucci, I., GATTA, C. L., Biase, D. D., Napoli, E. D., Paciello, O., Avallone, L., et al. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1274073 · Cited by 4

The crosstalk between CNS resident glial cells and peripheral immune cells is critical for age-dependent demyelination and subsequent remyelination

Jana, R., & Sarma, J. D. (2025) · Biogerontology · doi:10.1007/s10522-025-10213-2 · Cited by 4

Flexible ensheathment of axons enables myelination of complex CNS networks

Call, C. L., Neely, S. A., Early, J. J., James, O. G., Zoupi, L., Williams, A., Xu, Y. K. T., Chandran, S., Lyons, D. A., Monk, K. R., et al. (2026) · Nature · doi:10.1038/s41586-026-10312-1 · Cited by 4

Lipid Metabolism Reprogramming in the Aging Brain: Glial-Mediated Pathogenic Mechanisms and Translational Strategies in Neurodegeneration

Shao, W., Wang, K., Liu, Y., Zhang, H., Sun, Z., & Zhou, R. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27125580 · Cited by 4

Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development

Ma, T., Wang, Y., Yu, L., Liu, J., Wang, T., Sun, P., Feng, Y., Zhang, D., Shi, L., He, K., et al. (2024) · iScience · doi:10.1016/j.isci.2024.109180 · Cited by 5

Selenoprotein H mediates low selenium-related cognitive decline through impaired oligodendrocyte myelination with disrupted hippocampal lipid metabolism in female mice

Lv, Q., Yang, A., Han, Z., Yu, R., Zhu, J., Shi, Z., Yang, C., Dai, S., Hao, M., Chen, Y., et al. (2024) · Food & Function · doi:10.1039/d4fo00888j · Cited by 4

Hyperactivation of Hedgehog signaling impedes myelin development and repair via cholesterol dysregulation in oligodendrocytes

Fang, M., Wang, X., Chen, L., Li, F., Wang, S., Shen, L., Yang, H., Sun, L., Wang, X., Yang, J., et al. (2024) · iScience · doi:10.1016/j.isci.2024.111016 · Cited by 4

Waveform detection by deep learning reveals multi-area spindles that are selectively modulated by memory load

Mofrad, M. H., Gilmore, G., Koller, D. P., Mirsattari, S. M., Burneo, J. G., Steven, D. A., KHAN, A. R., Marti, A. S., & Muller, L. (2022) · eLife · doi:10.7554/elife.75769 · Cited by 4

Replenishing our mind orchards: Enhancing myelin renewal to rescue cognition in Alzheimer’s disease

McNamara, N. B., & Miron, V. E. (2021) · Neuron · doi:10.1016/j.neuron.2021.06.024 · Cited by 4

A comprehensive view of cell-type-specific temporal dynamics in human and mouse brainsPreprint

Lu, Z., Zhang, M., Lee, J., Sziraki, A., Anderson, S., Ge, S., Nelson, P. T., Zhou, W. Y., & Cao, J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.01.509820 · Cited by 4

Neurons sequester the cholesterol-inhibiting TFEB in oligodendrocyte cytoplasm to safeguard myelination and neural function

Zhang, Y., Cheng, Z., Huang, S., Sharma, T., Barbosa, D., Yu, G., & Sun, L. O. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116252 · Cited by 4

Clusterin induced by OPC phagocytosis blocks IL-9 secretion to inhibit myelination in a model of Alzheimer's disease

Beiter, R. M., Raghavan, T. P., Suchocki, O., Ennerfelt, H. E., Rivet-Noor, C. R., Merchak, A. R., Phillips, J. L., Bathe, T., Lukens, J. R., Prokop, S., et al. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e41635 · Cited by 4

Imaging myelin degradation in ex vivo prefrontal cortex tissue blocks in Alzheimer's disease and chronic traumatic encephalopathy

Novoseltseva, A., Küreli, G., Chang, S., Yang, J., Antinew, P. D., Chandra, A., Berghol, S. A., Spurlock, E., McKee, A. C., Huber, B. R., et al. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70582 · Cited by 4

β-glucan-loaded nano-niosomes ameliorate spatial and associative memory impairment in a D-galactose-induced aging rat model via modulation of microglial pyroptosis and autophagy

Rahmati‐Dehkordi, F., Zahedi, E., Adeli, S., Sahrayi, H., & Karimian, S. M. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118834 · Cited by 3

ACSS2 maintains oligodendrocyte progenitor cell pool and is required for myelination during development and aging

Gao, W., Chen, S., Huang, Y., (10164), X. W., Zhuang, L., Zheng, Y., Dai, X., Fu, Y., Chen, W., Ye, Q., et al. (2026) · Nature Aging · doi:10.1038/s43587-026-01071-9 · Cited by 4

The potential of circulating nonesterified fatty acids and sphingolipids in the biological understanding of cognitive decline and dementia

Moseholm, K. F., Meineche, J. T., & Jensen, M. K. (2024) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000968 · Cited by 3

Characterization of the Expression of Vacuolar Protein Sorting 11 (Vps11) in Mammalian Oligodendrocytes

Skoff, R. P., Bessert, D. A., Banerjee, S., Luo, X., & Thummel, R. (2021) · ASN NEURO · doi:10.1177/17590914211009851 · Cited by 3

Restored oligodendrogenesis by fibroblast growth factor 17: molecular mechanism for rejuvenating ageing-related memory deficit

Xiong, X., Semyanov, A. V., & Tang, Y. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01092-x · Cited by 3

Dynamic and Static Structure–Function Coupling With Machine Learning for the Early Detection of Alzheimer's Disease

Wu, H., Lu, Y., Wang, L., Wu, J., Liu, Y., & Zhang, Z. (2025) · Human Brain Mapping · doi:10.1002/hbm.70202 · Cited by 3

Cranial radiotherapy profoundly affects glia without inducing widespread cellular senescence

Kuil, L. E., van Scheppingen, R. H., Leter, Y. M., Röring, B. H., de Gooijer, M. C., Heijningen, C. L. V., Preković, S., Compter, A., van Tellingen, O., & Schagen, S. B. (2025) · Neuro-Oncology · doi:10.1093/neuonc/noaf146 · Cited by 3

[Mechanisms underlying remyelination with special focus on demyelination models of multiple sclerosis].

Zheng, S., & Zhao, J. (2020) · PubMed · doi:10.3785/j.issn.1008-9292.2020.08.12 · Cited by 3

Synaptic vesicle fusion along axons is driven by myelination and subsequently accelerates sheath growth in an activity-regulated mannerPreprint

Almeida, R., Williamson, J. M., Madden, M., Early, J. J., Voas, M. G., Talbot, W. S., Bianco, I. H., & Lyons, D. A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.28.271593 · Cited by 3

A COMPARATIVE ANALYSIS OF CONVECTIVE HEAT TRANSFER IN A NUCLEAR ROCKET NOZZLE

Neumann, H., & Bettinger, P. J. (1963) · University of Michigan Library Repository · Cited by 3

Oligomeric amyloid beta prevents myelination in a clusterin-dependent mannerPreprint

Beiter, R. M., Raghavan, T. P., Suchocki, O., Ennerfelt, H. E., Rivet-Noor, C. R., Merchak, A. R., Phillips, J. L., Bathe, T., Lukens, J. R., Prokop, S., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4415143/v1 · Cited by 3

Longitudinal trajectories of resilient psychosocial functioning link to ongoing cortical myelination and functional reorganization during adolescencePreprint

Hettwer, M. D., Dorfschmidt, L., Puhlmann, L. M. C., Jacob, L. M., Paquola, C., Bethlehem, R. A. I., Bullmore, E. T., Eickhoff, S. B., & Valk, S. (2024) · PsyArXiv (OSF Preprints) · doi:10.31234/osf.io/2dv68 · Cited by 3

Reorganizations of latency structures within the white matter from wakefulness to sleep

Guo, B., Zhou, F., Zou, G., Jiang, J., Gao, J., & Zou, Q. (2022) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2022.08.005 · Cited by 2

Role of the Gut Microbiota–Brain Axis in Brain Damage in Preterm Infants

Xiao, J. (2024) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.3c00369 · Cited by 2

Oligodendroglia in Ageing and Age-Dependent Neurodegenerative Diseases

Niu, J., Verkhratsky, A., Butt, A. M., & Yi, C. (2025) · Advances in neurobiology · doi:10.1007/978-3-031-87919-7_13 · Cited by 4

Discovery of oligodendrocyte enhancers that regulate Sox10 expression

An, H., Fan, C., Kim, D., Bui, H., & Park, Y. (2025) · PLoS Genetics · doi:10.1371/journal.pgen.1011778 · Cited by 3

Forelimb Motor Learning and Memory Consolidation Drives Distinct Oligodendrocyte Plasticity to Regulate Task‐related Neuronal Activity

Wang, S., Xu, N., Wang, W., He, Y., Yang, Y., Zhang, L., Zou, Y., He, Y., Li, H., Gao, L., et al. (2025) · Advanced Science · doi:10.1002/advs.202505367 · Cited by 7

Oral Intake of Plasticizer Di-(2-ethylhexyl) Phthalate Disrupts Cerebellar Myelination via Thyroid Signaling in Aging Mice

Wang, Q., Yang, F., Wang, X., Ma, X., Yang, X., Li, L., Cao, S., & Wa̅ng, Y. (2025) · Environment & Health · doi:10.1021/envhealth.5c00167 · Cited by 2

Clemastine ameliorates cognitive deficits in an experimental rat model of chronic cerebral hypoperfusion

Zong, X., Huang, Z., Kong, F., Feng, Y., Zhang, Y., Zou, P., Lin, H. W., Hess, D. C., & Zhang, Q. (2025) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x251382874 · Cited by 2

Piezo1 in the central nervous system: decoding the mechanical signature of neuroinflammation

Shi, G., Tan, R., Cao, Y., Zheng, X., & Zhan, R. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-026-03843-x · Cited by 4

Systems genetics analysis of the LXS recombinant inbred mouse strains:Genetic and molecular insights into acute ethanol tolerance

Radcliffe, R. A., Dowell, R. D., Odell, A. T., Richmond, P. A., Bennett, B., Larson, C., Kechris, K. J., Saba, L. M., Rudra, P., & Wen, S. (2020) · PLoS ONE · doi:10.1371/journal.pone.0240253 · Cited by 2

SnRNA-seq Interprets Mechanisms by which Three Glial Cell Types Influence Myelin Regeneration in Adult Drug-Resistant Epilepsy-Related Cognitive Impairment

Wang, L., Ma, J.-Q., Bian, Y., Qu, X.-P., Zhang, Y., Wang, C., Gao, G., Zheng, L., Fang, Q.-X., Song, L.-J., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05206-8 · Cited by 2

Oligodendrocyte lineage cells driven by neuronal activity in selected brain regions are required for episodic memory formationPreprint

Barboza, L. P., Bessières, B., Nazarzoda, O., & Alberini, C. M. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.10.472135 · Cited by 2

A hydrolyzed lipid blend diet promotes myelination in neonatal piglets in a region and concentration‐dependent manner

Louie, A. Y., Rund, L. A., Komiyama‐Kasai, K. A., Weisenberger, K. E., Stanke, K. L., Larsen, R. J., Leyshon, B. J., Kuchan, M. J., Das, T., & Steelman, A. J. (2023) · Journal of Neuroscience Research · doi:10.1002/jnr.25243 · Cited by 1

Positive effect of evobrutinib in CNS remyelination models and lack of synergy with clemastine—A dose response study

Martin, E., Aigrot, M., Frère, N., Lepaulmier, R., Stankoff, B., Boschert, U., Lubetzki, C., & Zalc, B. (2025) · Multiple Sclerosis Journal - Experimental Translational and Clinical · doi:10.1177/20552173251326913 · Cited by 1

4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione rescues oligodendrocytes ferroptosis leading to myelin loss and ameliorates neuronal injury facilitating memory in neonatal hypoxic-ischemic brain damage

Huang, Q., Tang, J., Xiang, Y., Shang, X., Li, K., Chen, L., Hu, J., Li, H., Pi, Y., Yang, H., et al. (2025) · Experimental Neurology · doi:10.1016/j.expneurol.2025.115262 · Cited by 1

Impact of Histone Acetyltransferases and Histone Deacetylases on Adult Brain Myelin Plasticity

Dominicis, A., Fabiano, T., Peria, S., Jaf, A. I. A. A., & Ragnini‐Wilson, A. (2025) · Results and problems in cell differentiation · doi:10.1007/978-3-031-91459-1_8 · Cited by 1

Oligodendrocyte precursor cell AMPA receptors differ with age and brain region while kainate receptors remain stable

Kamen, Y., Evans, K. A., Ng, Y. T., Dietmann, S., & Káradóttir, R. T. (2025) · iScience · doi:10.1016/j.isci.2025.113560 · Cited by 1

A bifunctional fluorescent probe for simultaneous imaging of myelin integrity and β-amyloid plaques in Alzheimer's disease progression

Wang, X., Liu, H., Wang, X., Wang, H., Lin, J., Luo, X., Yang, J.-J., Zhang, B., Chen, G., Zhu, H.-L., et al. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.168272 · Cited by 1

Oligodendrocytes at the crossroads: Central players and interactive partners in white matter aging

Zhang, X., Yu, P., Chen, Y., Xu, Y., Xu, R., Yang, X., Lv, S., Shang, H., & Hu, Y. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103034 · Cited by 1

Enhancing oligodendrocytes generation and myelin renewal by vitamin C mitigate Parkinson-relevant phenotypes in a murine model of Parkinson’s disease

Cui, S., Wang, S., Liu, M., Zou, Q., Cai, Z., & Ma, J. (2026) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2026.1761155 · Cited by 1

Targeting enhancing myelin regeneration reverses cognitive deficits in a mouse model of intellectual disability

Qiao, P., Wang, H., Qu, P., Guo, L., Zhou, Y., Zeng, T., Chen, J., Li, J., Hu, Y., & Chen, G. (2026) · Neurotherapeutics · doi:10.1016/j.neurot.2026.e00906 · Cited by 2

T cell-microglial interactions that impair myelin maintenance and regeneration: cellular mechanisms on white-matter associated changes

Song, C., Lee, Y., & Kim, M. S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1813048 · Cited by 1

Meningeal lymphatic dysfunction in Alzheimer’s disease: molecular mechanisms, clinical implications, and future perspectives

Liu, L., Li, J.-H., Bai, Y.-D., Wang, Y., & Bu, X. (2026) · Molecular Neurodegeneration · doi:10.1186/s13024-026-00962-0 · Cited by 1

Oligodendrocyte dysfunction in human age-related cognitive decline

Craig, G. A., Merour, E., Seeker, L. A., Haughian, A. J., Arbabi, K., Rose, J. L., Hoffmann, A., Thapar, J., Corsinotti, A., Mitchell, S., et al. (2026) · Nature Medicine · doi:10.1038/s41591-026-04608-y · Cited by 1

BDNF-TrkB Signaling in Lifelong Central Nervous System Myelination and Myelin Repair

Nicholson, M., Yoo, S., Craig, G. A., Murray, S. S., & Fletcher, J. L. (2021) · Springer eBooks · doi:10.1007/978-3-030-71519-9_219-1 · Cited by 2

Neuronal Stability, Volumetric Changes, and Decrease in GFAP Expression of Marmoset ( Callithrix jacchus ) Subcortical Visual Nuclei During Aging

Santana, N. N. M., Silva, E. H. A., dos Santos, S. F., Bezerra, L. L. F., da Silva, M. M. O., Cavalcante, J. S., Fiuza, F. P., Morais, P. L. A. D. G., & Engelberth, R. C. G. J. (2024) · The Journal of Comparative Neurology · doi:10.1002/cne.25649 · Cited by 1

LY2940094, an NOPR antagonist, promotes oligodendrocyte generation and myelin recovery in an NOPR independent manner

Duan, Y., Ye, C., Liao, J., & Xie, X. (2024) · Neurotherapeutics · doi:10.1016/j.neurot.2024.e00424 · Cited by 1

Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential and a population with transcriptional immune response

Fritze, J., Lang, S., Sommarin, M. N. E., Soneji, S., & Ahlenius, H. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1400963 · Cited by 1

Relationship between immediate memory, depressive symptomatology and loneliness in older adults: a longitudinal study

Abella, M., García‐Mollá, A., Sanz, A., Tomás, J. M., & Aliño, M. (2025) · Aging & Mental Health · doi:10.1080/13607863.2025.2478502 · Cited by 1

BDNF-TrkB Signaling in Lifelong Central Nervous System Myelination and Myelin Repair

Nicholson, M., Yoo, S., Craig, G. A., Murray, S. S., & Fletcher, J. L. (2022) · Springer eBooks · doi:10.1007/978-3-031-15080-7_219 · Cited by 1

Central nervous system hypomyelination disrupts axonal conduction and behaviour in larval zebrafishPreprint

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Li, Z., Fu, H., Liu, F., Wu, Y., & Wang, T. (2024) · Research Square · doi:10.21203/rs.3.rs-4466807/v1

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