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Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women
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Abstract Omega-3 fatty acids may influence human physiological parameters in part by affecting the gut microbiome. The aim of this study was to investigate the links between omega-3 fatty acids, gut microbiome diversity and composition and faecal metabolomic profiles in middle aged and elderly women. We analysed data from 876 twins with 16S microbiome data and DHA, total omega-3, and other circulating fatty acids. Estimated food intake of omega-3 fatty acids were obtained from food frequency questionnaires. Both total omega-3and DHA serum levels were significantly correlated with microbiome alpha diversity (Shannon index) after adjusting for confounders (DHA Beta(SE) = 0.13(0.04), P = 0.0006 total omega-3: 0.13(0.04), P = 0.001). These associations remained significant after adjusting for dietary fibre intake. We found even stronger associations between DHA and 38 operational taxonomic units (OTUs), the strongest ones being with OTUs from the Lachnospiraceae family (Beta(SE) = 0.13(0.03), P = 8 × 10 −7 ). Some of the associations with gut bacterial OTUs appear to be mediated by the abundance of the faecal metabolite N-carbamylglutamate. Our data indicate a link between omega-3 circulating levels/intake and microbiome composition independent of dietary fibre intake, particularly with bacteria of the Lachnospiraceae family. These data suggest the potential use of omega-3 supplementation to improve the microbiome composition.
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“Docosahexaenoic acid levels from subjects on an omega-3 diet strongly correlated with 38 operational taxonomic units from the Lachnospiraceae family (Menni et al., 2017)”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Menni et al., 2017
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“In humans, healthier polyunsaturated fatty acids (e.g., omega-3 PUFAs) promote the growth of beneficial bacteria, including butyrate producers such as Lactobacillus, Lachnospira, Roseburia, and Bifidobacterium (81), and are correlated with higher microbial diversity as well as taxa from the families Lachnospiraceae and Ruminococcaceae (82).”
From Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health (2021) · cites this paper as [82]
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“A recent study comparing 876 middle aged female subjects showed that the administration of omega-3 was able to modulate gut microbiota by significantly increasing α diversity (Menni et al., 2017).”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Menni et al., 2017
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Lin, G., Zhu, S., Wu, Y., Song, C., Wang, W., Zhang, Y., Chen, Y.-L., & He, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-03231-9 · Cited by 35
RetractedQIIME allows analysis of high-throughput community sequencing data
Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F. D., Costello, E. K., Fierer, N., Peña, A. G., Goodrich, J. K., Gordon, J. I., et al. (2010) · Nature Methods · doi:10.1038/nmeth.f.303 · Cited by 34,887
Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB
DeSantis, T. Z., Hugenholtz, P., Larsen, N., Rojas, M., Brodie, E. L., Keller, K., Huber, T., Dalevi, D., Hu, P., & Andersen, G. L. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.03006-05 · Cited by 10,891
Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample
Caporaso, J. G., Lauber, C. L., Walters, W. A., Berg-Lyons, D., Lozupone, C., Turnbaugh, P. J., Fierer, N., & Knight, R. D. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000080107 · Cited by 9,944
den Besten, G., van Eunen, K., Groen, A. K., Venema, K., Reijngoud, D.-J., & Bakker, B. M. (2013) · Journal of Lipid Research · doi:10.1194/jlr.r036012 · Cited by 5,048
Gut microbiota composition correlates with diet and health in the elderly
Claesson, M. J., Jeffery, I. B., Conde, S., Power, S. E., O’Connor, E. M., Cusack, S., Harris, H. M. B., Coakley, M., Lakshminarayanan, B., O’Sullivan, O., et al. (2012) · Nature · doi:10.1038/nature11319 · Cited by 3,314
Human Genetics Shape the Gut Microbiome
Goodrich, J. K., Waters, J. L., Poole, A. C., Sutter, J. L., Koren, O., Blekhman, R., Beaumont, M., Van Treuren, W., Knight, R., Bell, J. T., et al. (2014) · Cell · doi:10.1016/j.cell.2014.09.053 · Cited by 3,164
Self-citationTotal energy intake: implications for epidemiologic analyses.
WILLETT, W., & STAMPFER, M. J. (1986) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114366 · Cited by 2,751
RE: “TOTAL ENERGY INTAKE: IMPLICATIONS FOR EPIDEMIOLOGIC ANALYSES”
Palmgren, J., & Kushi, L. H. (1991) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115841 · Cited by 2,712
The Electronic Medical Records and Genomics (eMERGE) Consortium, Wood, A. R., The MIGen Consortium, The PAGE Consortium, Study, T. L. C., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., et al. (2014) · Nature Genetics · doi:10.1038/ng.3097 · Cited by 1,853
Toward Automatic Reconstruction of a Highly Resolved Tree of Life
Ciccarelli, F. D., Doerks, T., von Mering, C., Creevey, C. J., Snel, B., & Bork, P. (2006) · Science · doi:10.1126/science.1123061 · Cited by 1,663
Antibiotics in early life alter the murine colonic microbiome and adiposity
Cho, I., Yamanishi, S., Cox, L., Methé, B. A., Zavadil, J., Li, K., Gao, Z., Mahana, D., Raju, K., Teitler, I., et al. (2012) · Nature · doi:10.1038/nature11400 · Cited by 1,613
An atlas of genetic influences on human blood metabolites
The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Shin, S.-Y., Fauman, E. B., Petersen, A.-K., Krumsiek, J., Santos, R., Huang, J., Arnold, M., Erte, I., Forgetta, V., et al. (2014) · Nature Genetics · doi:10.1038/ng.2982 · Cited by 1,515
Self-citationOmega-3 Fatty Acids and Inflammatory Processes
Calder, P. C. (2010) · Nutrients · doi:10.3390/nu2030355 · Cited by 1,116
Biddle, A. S., Stewart, L. C., Blanchard, J. L., & Leschine, S. B. (2013) · Diversity · doi:10.3390/d5030627 · Cited by 1,071
HEALTH BENEFITS OF DOCOSAHEXAENOIC ACID (DHA)
Horrocks, L. A., & Yeo, Y. K. (1999) · Pharmacological Research · doi:10.1006/phrs.1999.0495 · Cited by 1,055
Genetic determinants of the gut microbiome in UK twins
Goodrich, J. K., Davenport, E. R., Beaumont, M., Jackson, M. A., Knight, R., Ober, C., Spector, T. D., Bell, J. T., Clark, A. G., & Ley, R. E. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.04.017 · Cited by 1,048
Self-citationSoininen, P., Kangas, A. J., Würtz, P., Suna, T., & Ala‐Korpela, M. (2015) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.114.000216 · Cited by 917
Proton pump inhibitors alter the composition of the gut microbiota
Jackson, M. A., Goodrich, J. K., Maxan, M.-E., Freedberg, D. E., Abrams, J. A., Poole, A. C., Sutter, J. L., Welter, D., Ley, R. E., Bell, J. T., et al. (2016) · Gut · doi:10.1136/gutjnl-2015-310861 · Cited by 895
Self-citationDuncan, S. H., Barcenilla, A., Stewart, C. S., Pryde, S. E., & Flint, H. J. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.10.5186-5190.2002 · Cited by 743
Petrof, E. O., Gloor, G. B., Vanner, S. J., Weese, S. J., Carter, D., Daigneault, M. C., Brown, E. M., Schroeter, K., & Allen-Vercoe, E. (2013) · Microbiome · doi:10.1186/2049-2618-1-3 · Cited by 731
Metabolite Profiling and Cardiovascular Event Risk
Würtz, P., Havulinna, A. S., Soininen, P., Tynkkynen, T., Prieto‐Merino, D., Tillin, T., Ghorbani, A., Artati, A., Wang, Q., Tiainen, M., et al. (2015) · Circulation · doi:10.1161/circulationaha.114.013116 · Cited by 680
Intestinal Microbiota Is Influenced by Gender and Body Mass Index
Haro, C., Rangel-Zúñiga, O. A., Alcalá-Díaz, J. F., Gómez-Delgado, F., Pérez-Martínez, P., Delgado-Lista, J., Quintana-Navarro, G. M., Landa, B. B., Navas-Cortés, J. A., Tena-Sempere, M., et al. (2016) · PLOS ONE · doi:10.1371/journal.pone.0154090 · Cited by 671
Takahashi, K., Nishida, A., Fujimoto, T., Fujii, M., Shioya, M., Imaeda, H., Inatomi, O., Bamba, S., Andoh, A., & Sugimoto, M. (2016) · Digestion · doi:10.1159/000441768 · Cited by 619
Kasai, C., Sugimoto, K., Moritani, I., Tanaka, J., Oya, Y., Inoue, H., Tameda, M., Shiraki, K., Ito, M., Takei, Y., et al. (2015) · BMC Gastroenterology · doi:10.1186/s12876-015-0330-2 · Cited by 581
Serhan, C. N., Dalli, J., Colas, R. A., Winkler, J. W., & Chiang, N. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.08.006 · Cited by 492
Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
Mottawea, W., Chiang, C., Mühlbauer, M., Starr, A. E., Butcher, J., Abujamel, T. S., Deeke, S. A., Brandel, A., Zhou, H., Shokralla, S., et al. (2016) · Nature Communications · doi:10.1038/ncomms13419 · Cited by 449
Comparative assessment of human and farm animal faecal microbiota using real-time quantitative PCR
Furet, J., Firmesse, O., Gourmelon, M., Bridonneau, C., Tap, J., Mondot, S., Dore, J. M., & Corthier, G. (2009) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2009.00671.x · Cited by 431
Nutritional methods in the European Prospective Investigation of Cancer in Norfolk
Bingham, S. A., Welch, A. A., McTaggart, A., Mulligan, A. A., Runswick, S. A., Luben, R., Oakes, S., Khaw, K., Wareham, N. J., & Day, N. (2001) · Public Health Nutrition · doi:10.1079/phn2000102 · Cited by 431
Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health
Vernocchi, P., Del Chierico, F., & Putignani, L. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01144 · Cited by 426
Day, N. (2001) · International Journal of Epidemiology · doi:10.1093/ije/30.2.309 · Cited by 416
Kaliannan, K., Wang, B., Li, X., Kim, K., & Kang, J. X. (2015) · Scientific Reports · doi:10.1038/srep11276 · Cited by 375
Docosahexaenoic acid concentrations are higher in women than in men because of estrogenic effects
Giltay, E. J., Gooren, L. J., Toorians, A. W. F. T., Katan, M., & Zock, P. L. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.5.1167 · Cited by 368
Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain
Menni, C., Jackson, M. A., Pallister, T., Steves, C. J., Spector, T. D., & Valdes, A. M. (2017) · International Journal of Obesity · doi:10.1038/ijo.2017.66 · Cited by 356
Self-citationGut microbiota diversity predicts immune status in HIV-1 infection
Nowak, P., Trøseid, M., Avershina, E., Barqasho, B., Neogi, U., Holm, K., Hov, J. R., Noyan, K., Vesterbacka, J., Svärd, J., et al. (2015) · AIDS · doi:10.1097/qad.0000000000000869 · Cited by 303
Rajkumar, H., Mahmood, N., Kumar, M., Varikuti, S. R., Challa, H. R., & Myakala, S. P. (2014) · Mediators of Inflammation · doi:10.1155/2014/348959 · Cited by 301
Metabolomic markers reveal novel pathways of ageing and early development in human populations
Menni, C., Kastenmüller, G., Petersen, A. K., Bell, J. T., Psatha, M., Tsai, P.-C., Gieger, C., Schulz, H., Erte, I., John, S., et al. (2013) · International Journal of Epidemiology · doi:10.1093/ije/dyt094 · Cited by 282
Self-citationCohort Profile: TwinsUK and Healthy Ageing Twin Study
Moayyeri, A., Hammond, C. J., Valdes, A. M., & Spector, T. D. (2012) · International Journal of Epidemiology · doi:10.1093/ije/dyr207 · Cited by 242
Self-citationArticulation rate and the duration of syllables and stress groups in connected speech
Crystal, T. H., & House, A. S. (1990) · The Journal of the Acoustical Society of America · doi:10.1121/1.399955 · Cited by 234
A metabolomic study of biomarkers of meat and fish intake
Cheung, W., Keski-Rahkonen, P., Assi, N., Ferrari, P., Freisling, H., Rinaldi, S., Slimani, N., Zamora-Ros, R., Rundle, M., Frost, G., et al. (2017) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.146639 · Cited by 206
Wu, X., Ruan, Z., Gao, Y., Yin, Y., Zhou, X., Wang, L., Geng, M., Hou, Y., & Wu, G. (2010) · Amino Acids · doi:10.1007/s00726-010-0538-y · Cited by 199
Effects of Fish Oil with a High Content of n-3 Polyunsaturated Fatty Acids on Mouse Gut Microbiota
Yu, H., Zhu, J., Pan, W., Shen, S., Shan, W., & Das, U. N. (2014) · Archives of Medical Research · doi:10.1016/j.arcmed.2014.03.008 · Cited by 177
Novel Proresolving Aspirin-Triggered DHA Pathway
Serhan, C. N., Fredman, G., Yang, R., Karamnov, S., Belayev, L., Bazan, N. G., Zhu, M., Winkler, J. W., & Petasis, N. A. (2011) · Chemistry & Biology · doi:10.1016/j.chembiol.2011.06.008 · Cited by 168
Understanding the Impact of Omega‐3 Rich Diet on the Gut Microbiota
Esquives, B. S. N., Sanchez‐Gonzalez, M. A., Salyakina, D., & Coffman, J. A. (2016) · Case Reports in Medicine · doi:10.1155/2016/3089303 · Cited by 167
Balfegó, M., Canivell, S., Hanzu, F. A., Sala‐Vila, A., Martínez-Medina, M., Murillo, S., Mur, T., Ruano, E. G., Linares, F., Porras, N., et al. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0245-0 · Cited by 147
Oliveira, V., Marinho, R., Vitorino, D., Santos, G. A., Moraes, J. C., Dragano, N., Sartori-Cintra, A., Pereira, L., Catharino, R. R., da Silva, A. S. R., et al. (2015) · Endocrinology · doi:10.1210/en.2014-1880 · Cited by 102
Pu, S., Khazanehei, H., Jones, P. J. H., & Khafipour, E. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01612 · Cited by 95
Shores, D. R., Binion, D. G., Freeman, B. Α., & Baker, P. R. S. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21560 · Cited by 87
EPA- and DHA-derived resolvins' actions in inflammatory bowel disease
Schwanke, R. C., Marcon, R., Bento, A. F., & Calixto, J. Β. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.08.050 · Cited by 85
Rajaei, E., Mowla, K., Ghorbani, A., Bahadoram, S., Bahadoram, M., & Dargahi-Malamir, M. (2015) · Global Journal of Health Science · doi:10.5539/gjhs.v8n7p18 · Cited by 85
Costa, K. A., Soares, A. D. N., Wanner, S. P., Santos, R. D. G. C. D., Fernandes, S. O. A., Martins, F. D. S., Nicoli, J. R., Coimbra, C. C., & Cardoso, V. N. (2014) · The Journal of Nutrition · doi:10.3945/jn.113.183186 · Cited by 84
Wong, R. G., Wu, J. R., & Gloor, G. B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161196 · Cited by 82
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Barbalho, S. M., Goulart, R. D. Á., Quesada, K. R., Bechara, M. D., & de Carvalho, A. D. C. A. (2016) · Europe PMC (PubMed Central) · Cited by 76
Jiang, J., Li, K., Wang, F., Yang, B., Fu, Y., Zheng, J., & Li, D. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147351 · Cited by 70
Zeng, X., Huang, Z., Mao, X., Wang, J., Wu, G., & Qiao, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041192 · Cited by 67
Wu, X., Zhang, Y., Liu, Z., Li, T. J., & Yin, Y. (2012) · Journal of Animal Science · doi:10.2527/jas.53752 · Cited by 64
Cao, W., Xiao, L., Liu, G., Fang, T., Wu, X., Jia, G., Zhao, H. Y., Chen, X., Wu, C., Cai, J., et al. (2016) · Food & Function · doi:10.1039/c5fo01194a · Cited by 64
Polyunsaturated fatty acids and suicide risk in mood disorders: A systematic review
Pompili, M., Longo, L., Dominici, G., Serafini, G., Lamis, D. A., Sarris, J. J., Amore, M., & Girardi, P. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.11.007 · Cited by 55
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Fritz, J. H. (2013) · Infection and Immunity · doi:10.1128/iai.00789-13 · Cited by 53
Casanova, M., Medeiros, F., Trindade, M., Cohen, C., Oigman, W., & Neves, M. F. (2016) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2016.10.004 · Cited by 53
Arnold, L. E., Young, A. S., Belury, M. A., Cole, R. M., Gracious, B., Seidenfeld, A. M., Wolfson, H. L., & Fristad, M. A. (2017) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2016.0123 · Cited by 53
Bønaa, K. H., Bjerve, K. S., & Nordøy, A. (1992) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.12.6.675 · Cited by 52
Smith, H. E., Ryan, K. N., Stephenson, K. B., Westcott, C., Thakwalakwa, C. M., Maleta, K. M., Cheng, J., Brenna, J. T., Shulman, R. J., Trehan, I., et al. (2014) · Journal of Nutrition · doi:10.3945/jn.114.201673 · Cited by 48
Fish oil supplements, longevity and aging
de Magalhães, J. P., Müller, M. M., Rainger, G. E., & Steegenga, W. T. (2016) · Aging · doi:10.18632/aging.101021 · Cited by 46
ω-3 fatty acids attenuate mucosal inflammation in premature rat pups
Ohtsuka, Y., Okada, K., Yamakawa, Y., Ikuse, T., Baba, Y., Inage, E., Fujii, T., Izumi, H., Oshida, K., Nagata, S., et al. (2011) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2010.07.032 · Cited by 44
Tabbaa, M., Golubić, M., Roizen, M. F., & Bernstein, A. (2013) · Nutrients · doi:10.3390/nu5083299 · Cited by 43
Bulaj, G. W., Ahern, M., Kuhn, A. K., Judkins, Z., Bowen, R. C., & Chen, Y. (2016) · Current Clinical Pharmacology · doi:10.2174/1574884711666160603012237 · Cited by 41
Dietary and enteral interventions for Crohn's disease
Yamamoto, T., Shimoyama, T., & Kuriyama, M. (2016) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2016.11.011 · Cited by 41
Chacher, B., Liu, H., Wang, D., & Liu, J. (2013) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/2049-1891-4-16 · Cited by 39
Liu, G., Xiao, L., Cao, W., Fang, T., Jia, G., Chen, X., Zhao, H. Y., Wu, C., & Wang, J. (2015) · Food & Function · doi:10.1039/c5fo01486g · Cited by 36
Reiner, M. F., Stivala, S., Limacher, A., Bonetti, N. R., Méan, M., Egloff, M., Rodondi, N., Aujesky, D., von Schacky, C., Lüscher, T. F., et al. (2017) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13553 · Cited by 32
ORTEGA, J. F., Morales‐Palomo, F., Fernández-Elías, V. E., Hamouti, N., Bernardo, F. J. G., Martín-Doimeadios, R. C. R., Nelson, R. K., Horowitz, J. F., & Mora‐Rodríguez, R. (2016) · Obesity · doi:10.1002/oby.21552 · Cited by 29
Barbosa, M. M. D. A. L., de Melo, A. L. T. R., & Damasceno, N. R. T. (2016) · Nutrition · doi:10.1016/j.nut.2016.08.010 · Cited by 27
Kristensen, S., Schmidt, E. B., Schlemmer, A., Rasmussen, C., Lindgreen, E., Johansen, M. B., & Christensen, J. H. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0382-5 · Cited by 25
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Howe, P. R. C., & Buckley, J. D. (2014) · Military Medicine · doi:10.7205/milmed-d-14-00154 · Cited by 22
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Ogawa, S., Abe, T., Nako, K., Okamura, M., Senda, M., Sakamoto, T., Ito, S., & the DIMS study group (2013) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.231.63 · Cited by 22
Mosca, L. J., Ballantyne, C. M., Bays, H. E., Guyton, J. R., Philip, S., Doyle, R. T., & Juliano, R. A. (2016) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2016.10.027 · Cited by 17
Baia, L. C., van den Berg, E., Vervloet, M. G., Heilberg, I. P., Navis, G. J., Bakker, S. J. L., Geleijnse, J. M., Kromhout, D., Soedamah‐Muthu, S. S., & de Borst, M. H. (2014) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2014.06.006 · Cited by 16
Effect of ω-3 Fatty Acid on Gastrointestinal Motility after Abdominal Operation in Rats
Zhang, Q., Yu, J., Kang, W., & Zhu, G.-J. (2011) · Mediators of Inflammation · doi:10.1155/2011/152137 · Cited by 14
Muldoon, M. F., Erickson, K. I., Goodpaster, B. H., Jakicic, J. M., Conklin, S. M., Sekikawa, A. M., Yao, J. K., & Manuck, S. B. (2013) · Journal of Nutrition · doi:10.3945/jn.113.174078 · Cited by 10
CO2 carbamylation of proteins as a mechanism in physiology
Meigh, L. (2015) · Biochemical Society Transactions · doi:10.1042/bst20150026 · Cited by 9
Kristensen, S., Schmidt, E. B., Schlemmer, A., Rasmussen, C., Lindgreen, E., Johansen, M. B., & Christensen, J. H. (2016) · Artery Research · doi:10.1016/j.artres.2016.10.053 · Cited by 7
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Metadata
- Authors
- Menni, C., Zierer, J., Pallister, T., Jackson, M. A., Long, T., Mohney, R. P., Steves, C. J., Spector, T. D., & Valdes, A. M.
- Affiliations
- King's College London (GB)
- Sanford Burnham Prebys Medical Discovery Institute (US)
- Metabolon (United States) (US)
- Corresponding author
- Valdes, Ana M.
- ORCID
- Venue
- Scientific Reports
- Published
- 2017-09-11
- Volume
- 7
- Issue
- 1
- Pages
- 11079-11079
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC5593975
- OpenAlex
- W2751449101
- Cited by
- 237
- References
- 82
- Citations by year
- 2026: 9 · 2025: 23 · 2024: 24 · 2023: 28 · 2022: 32 · 2021: 43 · 2020: 26 · 2019: 30 · 2018: 15 · 2017: 7
- FWCI
- 8.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Research Portal (King's College London) (submittedVersion, cc-by)
- Site cant be reached (submittedVersion, cc-by)
- PuSH - Publication Server of Helmholtz Zentrum München (submittedVersion)
- Funders
- Wellcome Trust (FP7/2007–2013, MR/M016560/1)
- National Institute for Health and Care Research (FP7/2007–2013, NF-SI-0507-10228, MR/M016560/1, NF-SI-0514-10027)
- King's College London
- European Commission (2007–2013, FP7 2007-2013, 603946, FP7/2007, MR/M016560/1)
- University of Nottingham
- National Institutes of Health (FP7/2007-2013, 1dp2od007444-01)
- Medical Research Council (FP7/20072013, MR/N030125/1, MR/N01183X/1, MR/M016560/1)
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK093595)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- omega-3 fatty acids, docosahexaenoic acid, gut microbiota diversity, N-carbamylglutamate, fecal metabolomics, Lachnospiraceae, middle-aged women, older women, dietary fiber intake, serum fatty acids, dietary intake, twins, omega-3 supplementation
- MeSH terms
- Gastrointestinal Microbiome, Aged, Aged, 80 and over, Docosahexaenoic Acids, Feces, Female, Glutamates, Humans, Middle Aged, Biomarkers, Fatty Acids, Omega-3, Fatty Acids, Omega-6, Biodiversity, Metabolomics, Metabolome
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