Cited by 60Menopause: Health Impacts and TreatmentsMindfulness and Compassion InterventionsCancer survivorship and care

Mindfulness-based stress reduction (MBSR) or psychoeducation for the reduction of menopausal symptoms: a randomized, controlled clinical trial

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Wong, Carmen, Yip, Benjamin Hon-Kei, Gao, Ting, Lam, Kitty Yu Yuk, Woo, Doris Mei Sum, Yip, Annie Lai King, Chin, Chloe Yu, Tang, Winnie Pui Yin +5 more·2018·Scientific Reports

Abstract

Psychological and behavioural interventions may be effective in reducing menopause-related symptoms. This randomized controlled trial aimed to evaluate the effectiveness of Mindfulness-based Stress Reduction (MBSR) in reducing menopause-related symptoms by comparing with an active control group, the menopause education control (MEC). Symptomatic peri-menopausal and post-menopausal women with mild to moderate symptoms were recruited. The primary outcome was overall menopausal symptoms measured by modified Greene Climacteric Scale (GCS). Secondary outcomes include subscales of the GCS perceived stress, mindfulness and health related Quality of Life. All outcome measures were collected at baseline, 2 months (immediately post intervention), 5 and 8 months (3 and 6 months post intervention respectively). Both MBSR (n = 98) and MEC (n = 99) groups reported a reduction in total GCS score at 8 months. Between group analysis show significant symptom score reduction in MBSR group on Anxiety and Depression subscales of GCS. No differences were found between groups on other GCS subscales and majority of the secondary outcome measures. The findings show that menopausal symptoms in both MBSR and MEC significantly reduced over the study period. MBSR show a greater reduction of psychological symptoms of depression and anxiety above active controls but do not reduce other somatic, urogenital and vasomotor symptoms.

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  • MBSR had no significant effect on health-related quality of life in peri- or postmenopausal women.

    “No significant effect on health-related quality of life.”

    From The effectiveness of psychosocial interventions on non-physiological symptoms of menopause: A systematic review and meta-analysis (2024) · cites this paper as *Wong et al. (2018)

    The Results (Secondary Outcome) report no significant difference between MBSR and menopause education on SF-12 health-related quality-of-life scores. They also report significant improvement in SF-12 scores over time across both groups, so the claim is supported only if “no significant effect” means no additional effect relative to the active control. (LLM, conf=0.87)

    Experimental — accuracy not yet measured
  • MBSR was not effective on the SF-12 (Wong et al., 2018).

    “but not SF-12 (12 item Short Form Health Survey; Wong et al., 2018).”

    From The effectiveness of psychosocial interventions on non-physiological symptoms of menopause: A systematic review and meta-analysis (2024) · cites this paper as Wong et al., 2018

    The Results (Secondary Outcome; page not provided) report no significant SF-12 difference between MBSR and psychoeducation, supporting a lack of demonstrated comparative benefit. But they also report SF-12 improvement over time in both groups, so saying MBSR was simply “not effective” overstates the finding. (LLM, conf=0.86)

    Experimental — accuracy not yet measured

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Authors
Wong, C., Yip, B. H.-K., Gao, T., Lam, K. Y. Y., Woo, D. M. S., Yip, A. L. K., Chin, C. Y., Tang, W. P. Y., Choy, M. M. T., Tsang, K. W. K., Ho, S. C., Ma, H. S. W., & Wong, S. Y. S.
Affiliations
  • Chinese University of Hong Kong (HK)
  • Hong Kong Polytechnic University (HK)
Corresponding author
Wong, Samuel Yeung Shan
Venue
Scientific Reports
Published
2018-04-26
Volume
8
Issue
1
Pages
6609-6609
ISSN
2045-2322 (ISSN-L)
OpenAlex
W2805811183
Cited by
60
References
60
Citations by year
2026: 10 · 2025: 12 · 2024: 9 · 2023: 4 · 2022: 6 · 2021: 13 · 2020: 3 · 2019: 3
FWCI
3.78
Type
journal article
Language
en
Open access
Locations
  • Scientific Reports (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • PolyU Institutional Research Archive (Hong Kong Polytechnic University) (submittedVersion)
Funders
Ministerio de Economía y Competitividad
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
Keywords
mindfulness-based stress reduction, menopausal symptoms, psychoeducation, menopause education, perimenopausal women, postmenopausal women, anxiety, depression, perceived stress, health-related quality of life, vasomotor symptoms, urogenital symptoms, somatic symptoms
MeSH terms
Adult, Female, Humans, Menopause, Middle Aged, Patient Compliance, Patient Education as Topic, Psychotherapy, Risk Factors, Severity of Illness Index, Socioeconomic Factors, Stress, Psychological, Treatment Outcome, Mindfulness

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