Using a Single Daytime Performance Test to Identify Most Individuals at High-Risk for Performance Impairment during Extended Wake
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We explored the predictive value of a neurobehavioral performance assessment under rested baseline conditions (evaluated at 8 hours awake following 8 hours of sleep) on neurobehavioral response to moderate sleep loss (evaluated at 20 hours awake two days later) in 151 healthy young participants (18–30 years). We defined each participant’s response-to-sleep-loss phenotype based on the number of attentional failures on a 10-min visual psychomotor vigilance task taken at 20 hours awake (resilient: less than 6 attentional failures, n = 26 participants; non-resilient: 6 or more attentional failures, n = 125 participants). We observed that 97% of rested participants with 2 or more attentional failures (n = 73 of 151) and 100% of rested participants with 3 or more attentional failures (n = 57 of 151) were non-resilient after moderate sleep loss. Our approach can accurately identify a significant proportion of individuals who are at high risk for neurobehavioral performance impairment from staying up late with a single neurobehavioral performance assessment conducted during rested conditions. Additional methods are needed to predict the future performance of individuals who are not identified as high risk during baseline.
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The Psychomotor Vigilance Task has been used to classify individuals regarding their vulnerability or susceptibility to sleep loss.
“Therefore, the PVT has been used to classify individuals regarding their vulnerability or susceptibility to sleep loss55,56.”
From Effects of total sleep deprivation on performance in a manual spacecraft docking task (2024) · cites this paper as [56]
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Effects of total sleep deprivation on performance in a manual spacecraft docking task
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- Authors
- St. Hilaire, M. A., Kristal, B. S., Rahman, S. A., Sullivan, J. P., Quackenbush, J., Duffy, J. F., Barger, L. K., Gooley, J. J., Czeisler, C. A., & Lockley, S. W.
- Affiliations
- Brigham and Women's Hospital (US)
- Dana-Farber Cancer Institute (US)
- National University of Singapore (SG)
- ORCID
- Venue
- Scientific Reports
- Published
- 2019-11-13
- Volume
- 9
- Issue
- 1
- Pages
- 16681-16681
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC6853981
- OpenAlex
- W2984514791
- Cited by
- 14
- References
- 48
- Citations by year
- 2025: 2 · 2024: 4 · 2022: 1 · 2021: 7
- FWCI
- 2.35
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
- Funders
- National Aeronautics and Space Administration (NNX14AK53G, NCC9-119)
- U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (5R01HL111759)
- National Space Biomedical Research Institute (HPF01301)
- U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01MH45130)
- U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (R01NS36590)
- U.S. Department of Health & Human Services | NIH | National Center for Research Resources (M01RR02635, UL1RR025758)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
- Keywords
- sleep deprivation, neurobehavioral performance, psychomotor vigilance task, attentional failures, extended wakefulness, high-risk identification
- MeSH terms
- Adolescent, Adult, Attention, Circadian Rhythm, Cognition, Female, Humans, Male, Prospective Studies, Psychomotor Performance, Reaction Time, Rest, Sleep, Sleep Deprivation, Wakefulness, Young Adult
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