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ECM formation and degradation during fibrosis, repair, and regeneration
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“Enzymatic ECM degradation and broad MMP activation can loosen structural constraints on tumor and stromal cells, and over-depletion of collagen or hyaluronan has been linked to enhanced invasion, metastatic dissemination and, in some settings, vascular complications [112].”
From Overcoming tumor microenvironment barriers: transformable and bioinspired nanomedicine strategies for deep tumor penetration (2026) · cites this paper as [112]
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Sheng, J., Yuan, W., Zhang, M., Chen, Z., Qi, Y., Zhao, Y., & Zhang, S. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04028-7 · Cited by 35
Metadata
- Authors
- Mayorca-Guiliani, A. E., Leeming, D. J., Henriksen, K., Mortensen, J. H., Nielsen, S. H., Anstee, Q. M., Sanyal, A. J., Karsdal, M. A., & Schuppan, D.
- Venue
- npj Metabolic Health and Disease
- Published
- 2025-06-10
- Volume
- 3
- Issue
- 1
- ISSN
- 2948-2828
- PMC
- PMC12441159
- Cited by
- 176
- References
- 37
- Language
- en
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