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Advances and challenges in smart and functional polymer vesicles
Abstract
Polymer vesicles prepared by self-assembly techniques have attracted increasing scientific interest in recent years. This is as a result of their numerous potential applications such as tunable delivery vehicles, for the templating of biomineralization, as nanoreactors and as scaffolds for biological conjugation. Presented in this review are the recent advances in the preparation and application of ‘smart’ and functional block copolymer vesicles such as those which respond to external stimuli to afford a change in structure, morphology or controlled release event. In this Highlight, we first give an overview of the structure of polymer vesicles, followed by a summary of the methods used for their preparation. We then focus on recently developed intelligent polymer vesicles which can respond to the application of external stimuli such as a change in temperature, pH or redox to afford novel nanomaterials. The potential applications of these materials are explored with specific focus on the functionalization of various domains of the polymer vesicles. Finally, the current limitations in the preparation and application of polymer vesicles are explored as are the challenges facing the development of these nanostructures towards real-world applications.
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Calcein Release from Polymeric Vesicles in Blood Plasma and PVA Hydrogel
Litvinchuk, S., Lu, Z., Rigler, P., Hirt, T. D., & Meier, W. P. (2009) · Pharmaceutical Research · doi:10.1007/s11095-009-9881-7 · Cited by 36
Wu, D. Q., Abezgauz, L., Danino, D., Ho, C., & Co, C. C. (2008) · Soft Matter · doi:10.1039/b715608a · Cited by 28
Gelation Inside Block Copolymer Aggregates and Organic/Inorganic Nanohybrids
Chen, Y., Du, J., Xiong, M., Zhang, K., & Zhu, H. (2006) · Macromolecular Rapid Communications · doi:10.1002/marc.200600128 · Cited by 24
Self-citation
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Thermoresponsive Polymers for Biomedical Applications
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Cascade Reactions in Multicompartmentalized Polymersomes
Peters, R. J. R. W., Marguet, M., Marais, S., Fraaije, M. W., van Hest, J. C. M., & Lecommandoux, S. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201308141 · Cited by 561
Metadata
- Authors
- Du, J., & O'Reilly, R. K.
- Venue
- Soft Matter
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2009
- Volume
- 5
- Issue
- 19
- Pages
- 3544
- ISSN
- 1744-683X (ISSN-L)
- 1744-6848
- OpenAlex
- W2171376065
- Cited by
- 572
- References
- 119
- FWCI
- 21.23
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
