The DOI matches its Crossref record; 180 of the 182 references it cites were found in a registry or an index.
THE PIG AS A MODEL FOR HUMAN WOUND HEALING
Abstract
The medical literature describes numerous in vitro and in vivo wound-healing models. The selection of an animal model depends on a number of factors including availability, cost, ease of handling, investigator familiarity, and anatomical/functional similarity to humans. Small mammals are frequently used for wound healing studies, however, these mammals differ from humans in a number of anatomical and physiological ways. Anatomically and physiologically, pig skin is more similar to human skin. The many similarities between man and pig would lead one to believe that the pig should make an excellent animal model for human wound healing. The purpose of this paper is to review the existing literature for evidence of this supposition and determine how well the various models correlate to human wound healing. Studies of wound dressings, topical antimicrobials, and growth factors are examined. Over 180 articles were utilized for this comparative review. Our conclusion is that the porcine model is an excellent tool for the evaluation of therapeutic agents destined for use in human wounds.
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In the citing paper
“domestic pigs representing a relevant animal model with a skin highly similar in its architecture to the human skin [25,26].”
In the citing paper
“The subcutaneous adipose tissue of the swine has a similarly high elastic and collagen fiber content and the animals show a healing mechanism comparable to humans.26,27,29”
From Detailed Analysis of Insulin Absorption Variability and the Tissue Response to Continuous Subcutaneous Insulin Infusion Catheter Implantation in Swine (2017) · cites this paper as [29]
In the citing paper
“Like humans it has a thick epidermis (70–150 μm), sparse body hair, and a similar composition of the skin lipid layer.26,29”
From Detailed Analysis of Insulin Absorption Variability and the Tissue Response to Continuous Subcutaneous Insulin Infusion Catheter Implantation in Swine (2017) · cites this paper as [29]
In the citing paper
“Although the inflammatory response may be different from humans, the swine has been described as the most adequate model for human wound healing.26–29”
From Detailed Analysis of Insulin Absorption Variability and the Tissue Response to Continuous Subcutaneous Insulin Infusion Catheter Implantation in Swine (2017) · cites this paper as [29]
In the citing paper
“Pig skin was selected based on the many characteristics it shares with human skin, including similarities in the thickness of skin layers, the types and distribution of skin cells, and the mechanisms of skin repair (15–18).”
From Candida auris Forms High-Burden Biofilms in Skin Niche Conditions and on Porcine Skin (2020) · cites this paper as [17]
In the citing paper
“In light of the similarities to human skin, porcine skin serves as an excellent model for studies of wound healing, infection, and skin colonization (15–18, 25).”
From Candida auris Forms High-Burden Biofilms in Skin Niche Conditions and on Porcine Skin (2020) · cites this paper as [17]
Citations
Cites
Pierschbacher, M. D., & Ruoslahti, E. I. (1984) · Nature · doi:10.1038/309030a0 · Cited by 3,690
Winter, G. D. (1962) · Nature · doi:10.1038/193293a0 · Cited by 2,261
Moritz, A. R., & Henriques, F. C. (1947) · PubMed · Cited by 1,198
Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes
Rheinwald, J. G., & Green, H. (1977) · Nature · doi:10.1038/265421a0 · Cited by 1,067
Interleukin 1, a potential regulator of fibroblast proliferation.
Schmidt, J. A., Mizel, S. B., Cohen, D. A., & Green, I. (1982) · The Journal of Immunology · doi:10.4049/jimmunol.128.5.2177 · Cited by 830
Effect of Air Exposure and Occlusion on Experimental Human Skin Wounds
HINMAN, C. D., & Maïbach, H. I. (1963) · Nature · doi:10.1038/200377a0 · Cited by 716
Enhancement of Wound Healing by Topical Treatment with Epidermal Growth Factor
Brown, G. L., Nanney, L. B., Griffen, J., Cramer, A. B., Yancey, J. M., Curtsinger, L. J., Holtzin, L., Schultz, G. S., Jurkiewicz, M. J., & Lynch, J. B. (1989) · New England Journal of Medicine · doi:10.1056/nejm198907133210203 · Cited by 682
Tumbleson, M. E. (1986) · Plenum Press eBooks · Cited by 672
Platelets as a source of fibroblast growth-promoting activity
Kohler, N., & Lipton, A. (1974) · Experimental Cell Research · doi:10.1016/0014-4827(74)90484-4 · Cited by 630
Steed, D. L., & the Diabetic Ulcer Study Group * (1995) · Journal of Vascular Surgery · doi:10.1016/s0741-5214(95)70245-8 · Cited by 610
Research works printed but not linked: 26
- Montagna W, 1964, The skin of the domestic pig, J Invest Dermatol, 43, 11
- Winter GD, 1966, PhD Thesis
- Forbes PD, 1969, Advances in the biology of skin: Hair growth, 419
- Nicolaides N, 1968, The skin surface lipids of man compared with those of eighteen species of animals, J Invest Derm, 51, 83
- Hartwell SW, 1955, The mechanism of healing in human wounds
- Lee KT, 1986, Swine in biomedical research, 1481
- Champsaur A, 1986, Use of DuoDerm on skin graft donor sites: comparative study with tulle gras, Ann Chir Plast Esthet, 31, 273
- Blitz H, 1985, Royal Society of Medicine International Congress and Symposium Series, No 88, 125
- Stair TO, 1984, Polyurethane and silver sulfadiazine dressings in treatments of partial‐thickness burns and abrasions, Am J Emerg Med, 214
- Mertz PM, 1988, Pulsed rhEGF treatment increased epithelialization of partial thickness wounds, J Invest Dermatol, 90, 588
- Pierce GF, 1992, Platelet‐derived growth factor (BB homodimer) transforming growth factor beta 1 and basic fibroblastic growth factor in dermal wound healing, Am J Path, 140, 1375
- Jyvasjarvi S, 1976, A model for studies of dermal surface epithelialization: with observations on the effects of dexamethasone and nandrolone deconate, Arzneim Forsch, 3, 443
- Mertz PM, 1986, Swine in biomedical research, 291
- Rives JM, 1997, Calcium alginate versus paraffin gauze in the treatment of scalp graft donor sites, Wounds, 9, 199
- Alvarez OM, 1984, Healing wounds: occlusion or exposure, Inf Surg, 173
- Gilbert EC, 1990, Hydrogel dressings II. Healing of full thickness skin wounds in swine; treatment with a new non‐occlusive hydrogel absorbent dressing, Wounds, 2, 56
- Bolton L, 1985, Models in dermatology, 145
- ConstableJ.Comparative effects of Betadine ointment (povidone‐iodine) and other topical agents on epidermal regeneration in rabbits. In:Proceedings from the Symposium Sponsored by the Department of Surgery;Durham (NC):1974.
- Mertz PM, 1985, Bactroban (Mupirocin) Proceedings of an International Symposium; 1984 May 21–22, 211
- White AR, 1985, Bactroban (Mupirocin) Proceedings of an International Symposium; 1984 May 21–22, 19
- Fuscher B, 1906, Organ fur amtliche und pracktische arzte Munch, Med Wochenschr, 42, 2041
- 10.1001/archsurg.1979.01370340094016 · DOI
- Danilenko DM, 1995, Growth factors in porcine full and partial thickness burn repair, Am J Pathol, 147, 1661
- Pierce GF, 1992, Platelet derived growth factor (BB homodimer), transforming growth fator‐beta 1 and basic fibroblast growth factor in dermal wound healing, Am J Pathol, 140, 1375
- Alvarez OM, 1981, Testosterone increases collagen deposition in experimentally induced granulation tissue, Fed Proc, 40, 343
- 10.1007/BF00412864 · DOI
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Fu, X., Cheong, Y. H., Ahamed, A., Zhou, C. Z., Robert, C., Krikstolaityte, V., Gordon, K. C., & Lisak, G. (2020) · Analytica Chimica Acta · doi:10.1016/j.aca.2020.10.056 · Cited by 2
Yergeshov, A. A., Siraeva, Z., Kazakova, R. R., Mullin, R. I., Давлиев, Д. М., Азатовна, З. А., Илшатовна, С. Т., Кузнецова, Е. В., Luong, D., Savina, I. N., et al. (2015) · Genes and Cells · doi:10.23868/gc120481 · Cited by 2
Miguel, S. P., Ribeiro, M. P., & Coutinho, P. (2021) · Springer eBooks · doi:10.1007/978-981-16-2677-7_15 · Cited by 2
Shoham, Y., Sabbag, I., & Singer, A. J. (2021) · Journal of Wound Care · doi:10.12968/jowc.2021.30.sup9a.vi · Cited by 2
Vlig, M., Boekema, B. K. H. L., & Ulrich, M. M. W. (2019) · Elsevier eBooks · doi:10.1016/b978-0-08-102546-8.00010-8 · Cited by 2
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Jørgensen, E., & Jacobsen, S. E. (2022) · Springer series on biofilms · doi:10.1007/978-3-031-10992-8_21 · Cited by 2
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Jaiswal, S., Sigaeva, T., Nadimpalli, S. P. V., Lieber, S. C., & Chester, S. A. (2023) · Mechanics Research Communications · doi:10.1016/j.mechrescom.2023.104098 · Cited by 2
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Zhang, X., Zhang, M., Li, Y., & Jiang, Y. (2024) · Gene · doi:10.1016/j.gene.2024.148141 · Cited by 2
Antonio, A. D. S., de Paula, A. D. R. U., Aguiar, A. T. C., da Costa, L. C. A., Ferreira-Keppler, R. L., Bentes, K. R. S., & Wiedemann, L. S. M. (2018) · Revista Virtual de Química · doi:10.21577/1984-6835.20180043 · Cited by 2
Carty, N., Leaper, D. J., Perry, L. C., & Edmiston, C. E. (2021) · American Journal of Infection Control · doi:10.1016/j.ajic.2021.01.016 · Cited by 2
Swindle, M. M. (2015) · CRC Press eBooks · doi:10.1201/b19430-4 · Cited by 2
Colbert, K. (2013) · KU ScholarWorks (The University of Kansas) · Cited by 2
Nuutila, K. (2013) · Työväentutkimus Vuosikirja · Cited by 2
Choice and characterization of preclinical models — Towards understanding wound healing
Hofmann, E., Nischwitz, S. P., Holzer, J., Kotzbeck, P., Birngruber, T., & Kamolz, L. (2019) · Burns · doi:10.1016/j.burns.2019.03.026 · Cited by 2
Burn assessment: A critical review on care, advances in burn healing and pre-clinical animal studies
Patel, R. J., DESAI, R., Patel, A. A., Shah, S., Prajapati, B. G., PATEL, V., & Alexander, A. (2023) · Journal of Research in Pharmacy · doi:10.29228/jrp.443 · Cited by 1
Evaluating the antimicrobial efficacy of long-lasting hand sanitizers on skin
Duggan, K., Bentley, K., Stanton, R. J., & Maillard, J. (2023) · Journal of Hospital Infection · doi:10.1016/j.jhin.2023.08.020 · Cited by 1
Davis, S. C., Gil, J., Solis, M., & Strong, R. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1501360 · Cited by 1
Self-citationTransplantation of Autologous Dermo-Epidermal Skin Substitutes in a Pig Model
Fleischmann, T., Nicholls, F., Lipiski, M., Arras, M., & Cesarovic, N. (2025) · Methods in molecular biology · doi:10.1007/978-1-0716-4510-9_21 · Cited by 1
Novel in vivo porcine models of chronic ischemic tissue
Frelichová, V., Bém, R., Chlupáč, J., Dubský, M., Husáková, J., Němcová, A., Voska, L., Šimůnková, Z., Tichánek, F., & Froněk, J. (2025) · Microvascular Research · doi:10.1016/j.mvr.2025.104845 · Cited by 1
Bush, K., Stephens, E. N., Kashgari, G., Chamberlain, A., & Kahn, S. A. (2025) · Journal of Burn Care & Research · doi:10.1093/jbcr/iraf219 · Cited by 1
Laorungrueng, H., Changprasoed, S., Keawbankrud, W., Juntrapirom, S., Kanjanakawinkul, W., Somwongin, S., Disayathanoowat, T., Tima, S., Anuchapreeda, S., Lin, W.-C., et al. (2025) · Industrial Crops and Products · doi:10.1016/j.indcrop.2025.121906 · Cited by 1
Efficacy of a novel thermo-reversible wound gel against antibiotic tolerant biofilm
Visvalingam, J., Muzaleva, A., Sailer, M., Logsetty, S., & Huizinga, R. B. (2026) · Frontiers in Antibiotics · doi:10.3389/frabi.2026.1773630 · Cited by 1
Metadata
- Authors
- Sullivan, T. P., Eaglstein, W. H., Davis, S. C., & Mertz, P.
- Affiliations
- University of Miami (US)
- Venue
- Wound Repair and Regeneration
- Publisher
- Wiley
- Published
- 2001-03
- Volume
- 9
- Issue
- 2
- Pages
- 66-76
- ISSN
- 1067-1927 (ISSN-L)
- 1524-475X
- OpenAlex
- W2060049869
- Cited by
- 1,091
- References
- 182
- Citations by year
- 2026: 69 · 2025: 47 · 2024: 65 · 2023: 54 · 2022: 67 · 2021: 72 · 2020: 63 · 2019: 62 · 2018: 65 · 2017: 56 · 2016: 72 · 2015: 63 · 2014: 49 · 2013: 48 · 2012: 43
- FWCI
- 1.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Wound Repair and Regeneration (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Wound Healing and Treatments
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Health Sciences › Veterinary › Small Animals › Animal testing and alternatives
- Keywords
- porcine model, porcine skin, wound dressings, topical antimicrobial agents, growth factors, translational validity
- MeSH terms
- Animals, Anti-Infective Agents, Burns, Debridement, Epidermal Growth Factor, Epidermis, Growth Substances, Homeostasis, Humans, Occlusive Dressings, Skin, Swine, Wound Healing, Fibroblast Growth Factor 2, Models, Animal
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