The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Regulation of Cholesterol Metabolism
Abstract
THE central features of the mechanisms by which cholesterol metabolism is regulated in intact animals were clearly elucidated in 1933 by Schoenheimer and Breusch1 — namely, that the synthesis, absorption and destruction of cholesterol in the mammal is controlled by complex interlocking feedback mechanism (or mechanisms), of which bile acids and cholesterol themselves are the principal mediators. In view of the fact that this superstructure for cholesterol metabolism was developed before the introduction of isotopic technics into biologic research, it is surprising that the intimate details of the regulatory mechanisms themselves and the means by which the regulatory mechanisms interdigitate . . .
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Citations
Cites
Evidence for a Negative-Feedback Mechanism in the Biosynthesis of Isoleucine
UMBARGER, H. E. (1956) · Science · doi:10.1126/science.123.3202.848 · Cited by 418
Feedback Control of Mevalonate Synthesis by Dietary Cholesterol
Siperstein, M. D., & Fagan, V. M. (1966) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96879-1 · Cited by 330
Grundy, S. M., & Ahrens, E. H. (1969) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42653-7 · Cited by 321
Mechanisms for the intestinal absorption of bile acids
Dietschy, J. M. (1968) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43096-2 · Cited by 305
Self-citationEffect of cholesterol feeding and fasting on sterol synthesis in seventeen tissues of the rat
Dietschy, J. M., & Siperstein, M. D. (1967) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38921-5 · Cited by 296
Self-citationLipid metabolism and atherosclerosis
Gould, R. G. (1951) · The American Journal of Medicine · doi:10.1016/0002-9343(51)90107-6 · Cited by 295
Turnover of plasma cholesterol in man
Goodman, D. S., & Noble, R. P. (1968) · Journal of Clinical Investigation · doi:10.1172/jci105719 · Cited by 292
Bucher, N. L. R., Overath, P., & Lynen, F. (1960) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(60)91390-1 · Cited by 288
The Effect of Palmityl Coenzyme A on Glucose 6-Phosphate Dehydrogenase and Other Enzymes
Taketa, K., & Pogell, B. M. (1966) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96898-5 · Cited by 273
STUDIES ON THE SITE OF THE FEEDBACK CONTROL OF CHOLESTEROL SYNTHESIS*†
Siperstein, M. D., & Guest, M. J. (1960) · Journal of Clinical Investigation · doi:10.1172/jci104079 · Cited by 272
Cited by
A Receptor-Mediated Pathway for Cholesterol Homeostasis
Brown, M. S., & Goldstein, J. L. (1986) · Science · doi:10.1126/science.3513311 · Cited by 5,703
The discovery and development of HMG-CoA reductase inhibitors.
Endo, A. (1992) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41379-3 · Cited by 847
Brown, M. S., & Goldstein, J. L. (1976) · Science · doi:10.1126/science.174194 · Cited by 725
Regulation of Plasma Cholesterol by Lipoprotein Receptors
Brown, M. S., Kovanen, P. T., & Goldstein, J. L. (1981) · Science · doi:10.1126/science.6261329 · Cited by 702
BROWN, M. S., KOVANEN, P. T., & GOLDSTEIN, J. L. (1979) · Proceedings of the 1978 Laurentian Hormone Conference · doi:10.1016/b978-0-12-571135-7.50009-6 · Cited by 311
Metadata
- Authors
- Dietschy, J. M., & Wilson, J. D.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1970-05-14
- Volume
- 282
- Issue
- 20
- Pages
- 1128-1138
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2465382919
- Cited by
- 361
- References
- 40
- FWCI
- 56.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dietschy, J. M., & Wilson, J. D. (1970). Regulation of Cholesterol Metabolism. New England Journal of Medicine. https://doi.org/10.1056/nejm197005142822005
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
