Cited by 853Lipoproteins and Cardiovascular HealthCholesterol and Lipid MetabolismHistorical Medical Research and Treatments

The discovery and development of HMG-CoA reductase inhibitors.

Open access
Endo, A·1992·Journal of Lipid Research

Abstract

During the 1950s and 1960s, many cholesterol-lowering agents were reported and introduced into clinical use, in-

Integrity signals

Registry

Crossref · 10.1016/s0022-2275(20)41379-3

Cites

114 of 114 references verified0 citation errors · 0 not checkable

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Authors
Endo, A.
Corresponding author
Endo, A
ORCID
Endo, A
Venue
Journal of Lipid Research
Publisher
Elsevier BV
Published
1992-11
Volume
33
Issue
11
Pages
1569-1582
ISSN
0022-2275 (ISSN-L)
OpenAlex
W2148463229
Cited by
847
References
114
Citations by year
2026: 11 · 2025: 19 · 2024: 31 · 2023: 22 · 2022: 25 · 2021: 26 · 2020: 23 · 2019: 20 · 2018: 35 · 2017: 28 · 2016: 37 · 2015: 41 · 2014: 39 · 2013: 43 · 2012: 35
FWCI
16.13
Type
journal article
Language
en
Open access
Locations
  • Journal of Lipid Research (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
  • Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Historical Medical Research and Treatments
Keywords
statins, cholesterol-lowering drugs, drug discovery, drug development
MeSH terms
Animals, Anticholesteremic Agents, Humans, Hypercholesterolemia, Lovastatin, Hydroxymethylglutaryl-CoA Reductase Inhibitors, History, 20th Century

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

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