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Cited by 2,740

The DOI matches its Crossref record.

Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction

DeWood, Marcus A., Spores, Julie, Notske, Robert, Mouser, Lowell T., Burroughs, Robert, Golden, Michael S., Lang, Henry T.·1980·New England Journal of Medicine
DOI 10.1056/nejm198010163031601
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Abstract

To define the prevalence of total coronary occlusion in the hours after transmural myocardial infarction, we used coronary arteriography to study the degree of coronary obstruction in 322 patients admitted within 24 hours of infarction. Total coronary occlusion was observed in 110 of 126 patients (87 per cent) who were evaluated within four hours of the onset of symptoms; this proportion decreased significantly, to 37 of 57 (65 per cent), when patients were studied 12 to 24 hours after the onset of symptoms. Among 59 patients with angiographic features of coronary thrombosis, the thrombus was retrieved by Fogarty catheter in 52 (88 per cent) but was absent in seven (12 per cent false positive). Among an additional 20 patients without angiographic features of thrombosis, a thrombus was discovered in five (25 per cent false negative). Thus, total coronary occlusion is frequent during the early hours of transmural infarction and decreases in frequency during the initial 24 hours, suggesting that coronary spasm or thrombus formation with subsequent recanalization or both may be important in the evolution of infarction.

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Metadata

Authors
DeWood, M. A., Spores, J., Notske, R., Mouser, L. T., Burroughs, R., Golden, M. S., & Lang, H. T.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1980-10-16
Volume
303
Issue
16
Pages
897-902
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm198010163031601
OpenAlex
W2336267479
Cited by
2,740
References
0
FWCI
46.52
Type
journal article
Language
en
Open access
closed

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