Cited by 82Down syndrome and intellectual disability researchNeurogenesis and neuroplasticity mechanismsGenetics and Neurodevelopmental Disorders

Evidence of Arrest of Neurogenesis and Synaptogenesis in Brains of Patients with Down's Syndrome

·1984·New England Journal of Medicine

Integrity signals

Registry

Crossref · 10.1056/nejm198411013111819

Cites

7 of 7 references verified0 citation errors · 0 not checkable

Statistics

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Claims the paper makes

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Claims other papers make about this one

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  • The fetal cortex, cerebellum and hippocampus have all been shown to contain fewer neurons in individuals with Down syndrome than in controls, albeit based on small sample sizes.

    “The fetal cortex, cerebellum and hippocampus have all been shown to contain fewer neurons in individuals with DS than in controls40–48, albeit based on small sample sizes17.”

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Venue
New England Journal of Medicine
Published
1984-11
Volume
311
Issue
18
Pages
1187-1188
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W4240806457
Cited by
82
References
7
Citations by year
2026: 1 · 2025: 2 · 2024: 5 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 2 · 2014: 1 · 2013: 3 · 2012: 3
FWCI
3.03
Type
journal article
Language
en
Open access
closed
Locations
New England Journal of Medicine (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Keywords
Down syndrome, neurogenesis, synaptogenesis, brain development

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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