Cited by 313Ovarian function and disordersDiabetes, Cardiovascular Risks, and LipoproteinsGenetic and Kidney Cyst Diseases

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Metformin for the Treatment of the Polycystic Ovary Syndrome

Nestler, John E.·2008·New England Journal of Medicine

DOI 10.1056/nejmct0707092

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Abstract

A 23-year-old woman with the polycystic ovary syndrome presents for evaluation and possible treatment. She has a family history of diabetes, is obese, and has impaired glucose tolerance. Metformin therapy is recommended. Metformin increases insulin sensitivity and may reduce the risk of diabetes. In the polycystic ovary syndrome, long-term metformin treatment may increase ovulation, improve menstrual cyclicity, and reduce serum androgen levels.

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Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011
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Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
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Metformin
Bailey, C. J., & Turner, R. C. (1996) · New England Journal of Medicine · doi:10.1056/nejm199602293340906 · Cited by 1,726
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Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., et al. (2005) · Cardiology in Review · doi:10.1097/01.crd.0000380842.14048.7e · Cited by 1,600
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Lillioja, S., Mott, D. M., Spraul, M., Ferraro, R., Foley, J. E., Ravussin, E., Knowler, W. C., Bennett, P. H., & Bogardus, C. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312303292703 · Cited by 1,508
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Ehrmann, D. A., Barnes, R. B., Rosenfield, R. L., Cavaghan, M. K., & Imperial, J. (1999) · Diabetes Care · doi:10.2337/diacare.22.1.141 · Cited by 1,257
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CHANG, R. J., NAKAMURA, R. M., JUDD, H. L., & KAPLAN, S. A. (1983) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-57-2-356 · Cited by 704
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10.1210/jc.83.6.2001 · DOI · Paper page
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Authors: Nestler, J. E.
Affiliations: Virginia Commonwealth University (US)
Corresponding author: Nestler, John E.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2008-01-03
Volume: 358
Issue: 1
Pages: 47-54
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmct0707092
OpenAlex: W2100076759
Semantic Scholar: f4b14c6984a40041406cef4211cbef144350d0fb
Cited by: 313
References: 60
Citations by year: 2026: 12 · 2025: 9 · 2024: 8 · 2023: 16 · 2022: 13 · 2021: 10 · 2020: 12 · 2019: 14 · 2018: 19 · 2017: 17 · 2016: 13 · 2015: 19 · 2014: 19 · 2013: 26 · 2012: 27
FWCI: 3.62
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
VCU Scholars Compass (Virginia Commonwealth University) (submittedVersion)
Funders: U.S. Public Health Service (K24D040237)
Fogarty International Center (D43TW007692)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD035629)
Topics: Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Kidney Cyst Diseases
Keywords: metformin, polycystic ovary syndrome, insulin sensitivity, impaired glucose tolerance, obesity, diabetes risk, ovulation, menstrual cyclicity, androgen reduction
MeSH terms: Adult, Female, Humans, Hypoglycemic Agents, Insulin Resistance, Cholesterol, LDL, Metformin, Obesity, Polycystic Ovary Syndrome, Triglycerides, Practice Guidelines as Topic

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Metformin for the Treatment of the Polycystic Ovary Syndrome

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