The role of lifestyle modification in polycystic ovary syndrome
Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine condition with reproductive and metabolic consequences, including anovulation, infertility and an increased prevalence of diabetes mellitus. Obesity, central obesity and insulin resistance are strongly implicated in its etiology and reduction of these risk factors should be a central treatment focus. Short-term weight loss has been consistently successful in reducing insulin resistance and restoring ovulation and fertility. However, problems arise with maintaining weight loss and precisely quantifying the associated long-term benefits of risk factor change. Although recent research indicates modest long-term lifestyle changes might reduce the extent of impaired glucose tolerance and delay the conversion to diabetes mellitus in the general population, this has not yet been examined in women with PCOS. Current conservative treatment should emphasize sustainable weight loss through dietary modification and exercise. Modifying additional lifestyle factors, including alcohol consumption, psychosocial stressors and smoking, are also crucial in long-term treatment of PCOS.
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A large proportion of the literature is focused on weight loss for individuals with PCOS.
“A large proportion of the literature is focused on weight loss for individuals with PCOS [42,43,44,45]”
From Moving beyond Weight: A Narrative Review of the Dietary and Lifestyle Management for Reducing Cardiometabolic Risk in Polycystic Ovary Syndrome (PCOS) (2023) · cites this paper as [44]
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- Authors
- Norman, R. J., Davies, M. J., Lord, J., & Moran, L. J.
- Affiliations
- Queen Elizabeth Hospital (AU)
- Derriford Hospital (GB)
- Corresponding author
- Norman, Robert J.
- Venue
- Trends in Endocrinology & Metabolism
- Publisher
- Elsevier BV
- Published
- 2002-08
- Volume
- 13
- Issue
- 6
- Pages
- 251-257
- ISSN
- 1043-2760 (ISSN-L)
- OpenAlex
- W2089499778
- Cited by
- 326
- References
- 8
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 10 · 2023: 13 · 2022: 19 · 2021: 18 · 2020: 12 · 2019: 9 · 2018: 8 · 2017: 11 · 2016: 12 · 2015: 9 · 2014: 12 · 2013: 14 · 2012: 16
- FWCI
- 2.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Endocrinology and Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Keywords
- polycystic ovary syndrome, lifestyle modification, weight loss, insulin resistance, obesity, anovulation, infertility, impaired glucose tolerance, diabetes mellitus, dietary change, physical activity, alcohol consumption, psychosocial stress, smoking
- MeSH terms
- Alcohol Drinking, Behavior Therapy, Body Composition, Diabetes Mellitus, Type 2, Diet, Female, Humans, Life Style, Obesity, Polycystic Ovary Syndrome, Smoking, Weight Loss, Exercise, Glucose Intolerance
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