Cited by 281Nutritional Studies and DietCardiovascular Health and Risk FactorsPhytochemicals and Antioxidant Activities

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Fresh Fruit Consumption and Major Cardiovascular Disease in China

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Du, Huaidong, Li, Liming, Bennett, Derrick, Guo, Yu, Key, Timothy J., Bian, Zheng, Sherliker, Paul, Gao, Haiyan, Chen, Yiping, Yang, Ling, Chen, Junshi, Wang, Shanqing, Du, Ranran, Su, Hua, Collins, Rory, Peto, Richard, Chen, Zhengming·2016·New England Journal of Medicine

DOI 10.1056/nejmoa1501451PMC PMC4896382

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Abstract

BACKGROUND: In Western populations, a higher level of fruit consumption has been associated with a lower risk of cardiovascular disease, but little is known about such associations in China, where the consumption level is low and rates of stroke are high. METHODS: Between 2004 and 2008, we recruited 512,891 adults, 30 to 79 years of age, from 10 diverse localities in China. During 3.2 million person-years of follow-up, 5173 deaths from cardiovascular disease, 2551 incident major coronary events (fatal or nonfatal), 14,579 ischemic strokes, and 3523 intracerebral hemorrhages were recorded among the 451,665 participants who did not have a history of cardiovascular disease or antihypertensive treatments at baseline. Cox regression yielded adjusted hazard ratios relating fresh fruit consumption to disease rates. RESULTS: Overall, 18.0% of participants reported consuming fresh fruit daily. As compared with participants who never or rarely consumed fresh fruit (the "nonconsumption" category), those who ate fresh fruit daily had lower systolic blood pressure (by 4.0 mm Hg) and blood glucose levels (by 0.5 mmol per liter [9.0 mg per deciliter]) (P<0.001 for trend for both comparisons). The adjusted hazard ratios for daily consumption versus nonconsumption were 0.60 (95% confidence interval [CI], 0.54 to 0.67) for cardiovascular death, and 0.66 (95% CI, 0.58 to 0.75), 0.75 (95% CI, 0.72 to 0.79), and 0.64 (95% CI, 0.56 to 0.74), respectively, for incident major coronary events, ischemic stroke, and hemorrhagic stroke. There was a strong log-linear dose-response relationship between the incidence of each outcome and the amount of fresh fruit consumed. These associations were similar across the 10 study regions and in subgroups of participants defined by baseline characteristics. CONCLUSIONS: Among Chinese adults, a higher level of fruit consumption was associated with lower blood pressure and blood glucose levels and, largely independent of these and other dietary and nondietary factors, with significantly lower risks of major cardiovascular diseases. (Funded by the Wellcome Trust and others.).

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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.
Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V., Abraham, J., Adair, T., Aggarwal, R., Ahn, S. Y., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61728-0 · Cited by 14,070
Self-citation
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Yusuf, S., Hawken, S., Ôunpuu, S., Dans, T., Avezum, A., Lanas, F., McQueen, M., Budaj, A., Pais, P., Varigos, J., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17018-9 · Cited by 12,026
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Lim, S. S., Vos, T., Flaxman, A. D., Danaei, G., Shibuya, K., Adair-Rohani, H., AlMazroa, M. A., Amann, M., Anderson, H. R., Andrews, K. G., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61766-8 · Cited by 11,805
Self-citation
Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals
Liu, R. H. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.3.517s · Cited by 2,213
Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010
Yang, G., Wang, Y., Zeng, Y., Gao, G. F., Liang, X., Zhou, M., Wan, X., Yu, S., Jiang, Y., Naghavi, M., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)61097-1 · Cited by 1,984
Use and misuse of population attributable fractions
Rockhill, B., Newman, B., & Weinberg, C. (1998) · American Journal of Public Health · doi:10.2105/ajph.88.1.15 · Cited by 1,683
The burden and costs of chronic diseases in low-income and middle-income countries.
Abegunde, D. O., Mathers, C. D., Adam, T., Ortegon, M., & Strong, K. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61696-1 · Cited by 1,603
Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: systematic review and dose-response meta-analysis of prospective cohort studies
Wang, X., Ouyang, Y., Liu, J., Zhu, M., Zhao, G., Bao, W., & Hu, F. B. (2014) · BMJ · doi:10.1136/bmj.g4490 · Cited by 1,596
Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies
Dauchet, L., Amouyel, P., Hercberg, S., & Dallongeville, J. (2006) · The Journal of Nutrition · doi:10.1093/jn/136.10.2588 · Cited by 1,204
China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up
Chen, Z., Chen, J., Collins, R., Guo, Y., Peto, R., Wu, F., Li, L., & on behalf of the China Kadoorie Biobank (CKB) collaborative group (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr120 · Cited by 1,034
Self-citation

Show all 35 references

Research works printed but not linked: 4

Yang GH, 1997, Biomed Environ Sci, 10, 1
Xiao Y, 2015, Zhonghua Liu Xing Bing Xue Za Zhi, 36, 232
10.1097/00043798-200304000-00010 · DOI
Hartley L, 2013, Cochrane Database Syst Rev, 6, CD009874

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Self-citation
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Sun, Y., Gregersen, H. N., & Yuan, W. (2017) · Clinical Epidemiology · doi:10.2147/clep.s106258 · Cited by 92
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McDonough, A. A., Veiras, L. C., Guevara, C. A., & Ralph, D. L. (2017) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00453.2016 · Cited by 75
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Genetic risk, adherence to a healthy lifestyle, and type 2 diabetes risk among 550,000 Chinese adults: results from 2 independent Asian cohorts
Li, H., Khor, C. C., Fan, J., Lv, J., Yu, C., Guo, Y., Bian, Z., Yang, L., Millwood, I. Y., Walters, R. G., et al. (2019) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqz310 · Cited by 73
Self-citation
Nutrition, Thrombosis, and Cardiovascular Disease
Violi, F., Pastori, D., Pignatelli, P., & Carnevale, R. (2020) · Circulation Research · doi:10.1161/circresaha.120.315892 · Cited by 72
Important food sources of fructose-containing sugars and incident gout: a systematic review and meta-analysis of prospective cohort studies
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Joshi, S., Ettinger, L., & Liebman, S. E. (2019) · American Journal of Lifestyle Medicine · doi:10.1177/1559827619875411 · Cited by 72
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Liu, T., Zhou, C., Zhang, H., Huang, B., Xu, Y., Lin, L., Wang, L., Hu, R., Hou, Z., Xiao, Y., et al. (2020) · The Innovation · doi:10.1016/j.xinn.2020.100072 · Cited by 65
Self-citation
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on behalf of the China Kadoorie Biobank collaborative group, Du, H., Yu, C., Bennett, D., Bragg, F., Bian, Z., Chadni, M., Yu, C., Chen, Y., Tan, Y., et al. (2020) · Diabetologia · doi:10.1007/s00125-020-05091-x · Cited by 65
Self-citation
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Wang, D., Tian, L., Lv, H., Pang, Z., Li, D., Yao, Z., & Wang, S. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110773 · Cited by 61
Self-citation
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Self-citation
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Kalt, W. (2019) · Molecules · doi:10.3390/molecules24224024 · Cited by 61
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Authors: Du, H., Li, L., Bennett, D., Guo, Y., Key, T. J., Bian, Z., Sherliker, P., Gao, H., Chen, Y., Yang, L., Chen, J., Wang, S., Du, R., Su, H., Collins, R., Peto, R., & Chen, Z.
Affiliations: Peking University (CN)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
ORCID: Li, Liming
Bennett, Derrick
Key, Timothy J.
Sherliker, Paul
Gao, Haiyan
Chen, Yiping
Yang, Ling
Chen, Junshi
Wang, Shanqing
Su, Hua
Collins, Rory
Peto, Richard
Chen, Zhengming
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2016-04-07
Volume: 374
Issue: 14
Pages: 1332-1343
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmoa1501451
PMC: PMC4896382
OpenAlex: W2314578140
Cited by: 281
References: 35
Citations by year: 2026: 5 · 2025: 14 · 2024: 22 · 2023: 24 · 2022: 38 · 2021: 41 · 2020: 39 · 2019: 30 · 2018: 28 · 2017: 26 · 2016: 13
FWCI: 32.06
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Pure (Coventry University) (publishedVersion)
PubMed Central (acceptedVersion)
Funders: Wellcome Trust (104085, 088158)
Cancer Research UK (A8760, 16491)
British Heart Foundation
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Keywords: fresh fruit consumption, cardiovascular disease, ischemic stroke, intracerebral hemorrhage, coronary events, cardiovascular mortality, blood pressure, blood glucose, dose-response relationship, Chinese adults, diet and cardiovascular risk
MeSH terms: Adult, Aged, Blood Glucose, Blood Pressure, Cardiovascular Diseases, China, Diet, Diet Surveys, Female, Follow-Up Studies, Fruit, Humans, Hyperglycemia, Hypertension, Male, Middle Aged, Risk Factors, Body Mass Index, Proportional Hazards Models

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Fresh Fruit Consumption and Major Cardiovascular Disease in China

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