The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Heat Stroke
Abstract
Knowledge of the molecular and cellular events in heat stroke has advanced steadily during the past decade. It is now known that heat stroke is associated with injury to multiple tissues and organs as a result not only of the cytotoxic effect of heat, but also of the inflammatory and coagulation responses of the patient. Altered expression of heat-shock proteins may also have a role in the pathogenesis of heat stroke. This article reviews current understanding of the pathophysiology of heat stroke and advances in therapy.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Severe CBT deviations (<33 °C or >40 °C) can even have life-threatening consequences3.”
From Increased core body temperature in astronauts during long-duration space missions (2017) · cites this paper as [3]
Citations
Cites
Acute-Phase Proteins and Other Systemic Responses to Inflammation
Gabay, C., & Kushner, I. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400607 · Cited by 6,734
Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
Bernard, G. R., Vincent, J., Laterre, P., LaRosa, S. P., Dhainaut, J.-F., Lopez-Rodriguez, A., Steingrub, J. S., Garber, G. E., Helterbrand, J. D., Ely, E. W., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200103083441001 · Cited by 6,124
Climate Extremes: Observations, Modeling, and Impacts
Easterling, D. R., Meehl, G. A., Parmesan, C., Changnon, S. A., Karl, T. R., & Mearns, L. O. (2000) · Science · doi:10.1126/science.289.5487.2068 · Cited by 4,945
NF-κB: a key role in inflammatory diseases
Tak, P. P., & Firestein, G. S. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11830 · Cited by 3,918
Exercise and the immune system: regulation, integration, and adaptation
Pedersen, B. K., & Hoffman-Goetz, L. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.3.1055 · Cited by 1,710
Xing, Z., Gauldie, J., Cox, G., Baumann, H., Jordana, M., Lei, X.-F., & Achong, M. K. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1368 · Cited by 1,578
Heat-Related Deaths during the July 1995 Heat Wave in Chicago
Semenza, J. C., Rubin, C., Falter, K. H., Selanikio, J., Flanders, W. D., Howe, H. L., & Wilhelm, J. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607113350203 · Cited by 1,381
Welch, W. J. (1992) · Physiological Reviews · doi:10.1152/physrev.1992.72.4.1063 · Cited by 1,190
Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running
Ostrowski, K., Rohde, T., Zacho, M., Asp, S., & Pedersen, B. K. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.949bp.x · Cited by 673
Heat Shock Is Lethal to Fibroblasts Microinjected with Antibodies Against hsp70
Riabowol, K. T., Mizzen, L., & Welch, W. J. (1988) · Science · doi:10.1126/science.3175665 · Cited by 631
Flagged first, then by citations
Research works printed but not linked: 14
- Knochel JP, Reed G. Disorders of heat regulation. In: Narins RG, ed. Maxwell & Kleeman's clinical disorders of fluid and electrolyte metabolism. 5th ed. New York: McGraw-Hill, 1994:1549-90.
- 2000, MMWR Morb Mortal Wkly Rep, 49, 470
- Gathiram P, 1988, Circ Shock, 25, 223
- Gathiram P, 1987, Circ Shock, 23, 157
- Lin MT, 1997, Am J Physiol, 273, H2072
- Yang YL, 1999, Am J Physiol, 276, H1961
- Cannon JG, 2000, News Physiol Sci, 15, 298
- Hall DM, 1999, Am J Physiol, 276, G1195
- Buckley IK, 1972, Lab Invest, 26, 201
- Sakaguchi Y, 1995, Cancer Res, 55, 5459
- Bynum GD, 1978, Am J Physiol, 235, R228
- Malamud N, 1946, Mil Surg, 99, 397
- Lefor AT, 1994, Surgery, 116, 214
- Knochel JP. Pigment nephropathy. In: Greenberg A, Cheung AK, eds. Primer on kidney diseases. 2nd ed. San Diego, Calif.: Academic Press, 1998:273-6.
Cited by
Sorted by citations
Items 601–700 of 1,000
Rosa caninaL. methanolic extract prevents heat stress‐induced memory dysfunction in rats
Erfani, M., Tabatabaei, Z. G., Sadigh‐Eteghad, S., Farokhi-Sisakht, F., Farajdokht, F., Mahmoudi, J., Karimi, P., & Nasrolahi, A. (2019) · Experimental Physiology · doi:10.1113/ep087535 · Cited by 30
Zhang, X., Chen, B., Wu, J., Sha, J., Yang, B., Zhu, J., Sun, J., Hartung, J., & Bao, E. (2020) · Cells · doi:10.3390/cells9010243 · Cited by 30
Harris, B. A., Andrews, P., Marshall, I., Robinson, T. M., & Murray, G. D. (2008) · British Journal of Anaesthesia · doi:10.1093/bja/aem405 · Cited by 30
Toni, L. D., Finocchi, F., Jawich, K., & Ferlin, A. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1104326 · Cited by 35
Emergency Department Visits for Heat Stroke in the United States, 2009 and 2010
Wu, X., Brady, J. E., Rosenberg, H. R., & Li, G. (2014) · Injury Epidemiology · doi:10.1186/2197-1714-1-8 · Cited by 29
Matsumoto, H., Takeba, J., Umakoshi, K., Nakabayashi, Y., Moriyama, N., Annen, S., Ohshita, M., Kikuchi, S., Sato, N., & Aibiki, M. (2019) · Journal of Intensive Care · doi:10.1186/s40560-019-0359-3 · Cited by 29
Analysis of Clinical Symptoms and Brain MRI of Heat Stroke: 2 Case Reports and a Literature Review
Shimada, T., Miyamoto, N., Shimada, Y., Watanabe, M., Shimura, H., Ueno, Y., Yamashiro, K., Hattori, N., & Urabe, T. (2019) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2019.104511 · Cited by 29
Schleypen, J. R., Mistry, M., Saeed, F., & Dasgupta, S. (2021) · Spatial Economic Analysis · doi:10.1080/17421772.2021.1904150 · Cited by 29
Lahimer, A. A., Razak, A. A., Sharol, A. F., & Sopian, K. (2023) · Solar Energy · doi:10.1016/j.solener.2023.05.039 · Cited by 29
Li, C.-W., Lin, Y., Liu, T., & Wang, J. (2013) · Experimental Biology and Medicine · doi:10.1177/1535370213493705 · Cited by 29
Wang, Q., Ishikawa, T., Michiue, T., Zhu, B.-L., Guan, D., & Maeda, H. (2012) · Forensic Science International · doi:10.1016/j.forsciint.2012.01.015 · Cited by 29
Moon, P., & Kim, H. M. (2011) · Phytotherapy Research · doi:10.1002/ptr.3627 · Cited by 29
Exertional Heat Stroke in Navy and Marine Personnel: A Hot Topic
Goforth, C. W., & Kazman, J. B. (2015) · Critical Care Nurse · doi:10.4037/ccn2015257 · Cited by 29
Prevalence of genital human papillomavirus among Lebanese women.
Mroueh, A. M., Seoud, M. A.-F., Kaspar, H. G., & Zalloua, P. (2002) · PubMed · Cited by 29
Chang, C., Chen, J., Chen, S.-H., Cheng, T., Lin, M., & Hu, M. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.12.017 · Cited by 28
Zoorob, R., Parrish, M.-E. E., O’Hara, H., & Kalliny, M. (2013) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2013.02.013 · Cited by 28
Xu, Q., Guo, X., Liu, J., Chen, B., Liu, Z., & Su, L. (2014) · Cell Biology International · doi:10.1002/cbin.10408 · Cited by 28
The influence of physiological and pathological perturbations on blood-brain barrier function
Zhao, N., Chung, T. D., Guo, Z., Jamieson, J. J., Liang, L. R., Linville, R. M., Pessell, A. F., Wang, L., & Searson, P. C. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1289894 · Cited by 31
The pathogenesis and therapeutic strategies of heat stroke-induced myocardial injury
Xia, R., Sun, M., Li, Y., Yin, J., Liu, H., Yang, J., Liu, J., He, Y., Wu, B., Yang, G., et al. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1286556 · Cited by 30
Gao, X., & Chen, H. (2014) · Frontiers of Medicine · doi:10.1007/s11684-014-0309-3 · Cited by 28
Impact of heat waves on nonaccidental deaths in Jinan, China, and associated risk factors
Zhang, J., Liu, S., Han, J., Zhou, L., Liu, Y., Yang, L., Zhang, J., & Zhang, Y. (2016) · International Journal of Biometeorology · doi:10.1007/s00484-015-1130-7 · Cited by 28
Gait instability and estimated core temperature predict exertional heat stroke
Buller, M. J., Fellin, R. E., Bursey, M., Galer, M., Atkinson, E. Y., Beidleman, B. A., Marcello, M. J., Driver, K. A., Mesite, T. J., Seay, J. F., et al. (2022) · British Journal of Sports Medicine · doi:10.1136/bjsports-2021-104081 · Cited by 28
Critical illness aspects of heatstroke: A hot topic
Patel, J., Boyer, N., Mensah, K., Haider, S. S., Gibson, O. R., Martín, D., & Walter, E. J. (2023) · Journal of the Intensive Care Society · doi:10.1177/17511437221148922 · Cited by 28
Sharma, H. S., & Sharma, A. (2010) · Springer eBooks · doi:10.1007/978-90-481-8553-5_9 · Cited by 27
Akagi, R., Ohno, M., Matsubara, K., Fujimoto, M., Nakai, A., & Inouye, S. (2013) · Pharmacology · doi:10.1159/000345930 · Cited by 28
Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats
Wu, W.-S., Chou, M., Chao, C., Chang, C.-K., Lin, M.-T., & Chang, C. (2012) · Acta Pharmacologica Sinica · doi:10.1038/aps.2012.29 · Cited by 28
Herbst, J. B., Mason, K. E., Byard, R. W., Gilbert, J. D., Charlwood, C., Heath, K. J., Winskog, C., & Langlois, N. E. I. (2013) · Journal of Forensic and Legal Medicine · doi:10.1016/j.jflm.2013.12.018 · Cited by 28
The effect of pre-existing medical conditions on heat stroke during hot weather in South Korea
Kim, S.-H., Jo, S.-N., Myung, H.-N., & Jang, J.-Y. (2014) · Environmental Research · doi:10.1016/j.envres.2014.06.003 · Cited by 28
Themes and Variations in ER/SR Calcium Release Channels: Structure and Function
Stathopulos, P. B., Seo, M., Enomoto, M., Amador, F. J., Ishiyama, N., & Ikura, M. (2012) · Physiology · doi:10.1152/physiol.00013.2012 · Cited by 28
Serum histones as biomarkers of the severity of heatstroke in dogs
Bruchim, Y., Ginsburg, I., Segev, G., Mreisat, A., Avital, Y., Aroch, I., & Horowitz, M. (2017) · Cell Stress and Chaperones · doi:10.1007/s12192-017-0817-6 · Cited by 28
Goldenshluger, M., Zippel, D. B., Ben‐Yaacov, A., Dux, J., Yalon, T., Zendel, A., Rayman, S., Mor, E., Berkenstadt, H., Fogel‐Grinvald, H., et al. (2017) · Annals of Surgical Oncology · doi:10.1245/s10434-017-6279-3 · Cited by 28
Exertional Heat Illness and Hyponatremia
Carter, R. (2008) · Current Sports Medicine Reports · doi:10.1249/jsr.0b013e31817f38ff · Cited by 28
Zhao, J., Yang, F., Guo, Y., & Ren, X. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-25207-1 · Cited by 27
Lin, Y.-C., Jung, C., Hwang, B., & Chen, C. (2025) · Urban Climate · doi:10.1016/j.uclim.2025.102322 · Cited by 27
Plasma and lymphocyte Hsp72 responses to exercise in athletes with prior exertional heat illness
Ruell, P. A., Simar, D., Périard, J. D., Best, S. A., Caillaud, C., & Thompson, M. W. (2014) · Amino Acids · doi:10.1007/s00726-014-1721-3 · Cited by 27
Increased cytokine and chemokine gene expression in the CNS of mice during heat stroke recovery
Biedenkapp, J. C., & Leon, L. R. (2013) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00011.2013 · Cited by 27
Wang, D., Cai, M., Wang, T., Zhao, G., Huang, J., Wang, H., Qian, F., Ho, C., & Wang, Y. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.04.001 · Cited by 27
Long-Term Cardiovascular Diseases of Heatstroke: A Delayed Pathophysiology Outcome
Nzvere, F. P., Tariq, E. F., Katukuri, N., Arshid, A., & Cancarevic, I. (2020) · Cureus · doi:10.7759/cureus.9595 · Cited by 27
Inpatient burden and mortality of heatstroke in the United States
Kaewput, W., Thongprayoon, C., Petnak, T., Cato, L. D., Chewcharat, A., Boonpheng, B., Bathini, T. J., Vallabhajosyula, S., & Cheungpasitporn, W. (2020) · International Journal of Clinical Practice · doi:10.1111/ijcp.13837 · Cited by 28
Kuczmarski, T. M., Fox, J. A., Katznelson, E., Thakral, D., Aung, K.-K., Moore, E., Eisen, J., Slutzman, J. E., LaRocque, R. C., Solomon, C. G., et al. (2021) · The Journal of Climate Change and Health · doi:10.1016/j.joclim.2021.100067 · Cited by 30
Risk factors for heat-related illnesses during the Hajj mass gathering: an expert review
Yezli, S. (2021) · Reviews on Environmental Health · doi:10.1515/reveh-2021-0097 · Cited by 29
Sharma, H. S. (2007) · Progress in brain research · doi:10.1016/s0079-6123(06)62015-3 · Cited by 28
Perioperative temperature elevation: not all hyperthermia is malignant hyperthermia
Herlich, A. (2013) · Pediatric Anesthesia · doi:10.1111/pan.12244 · Cited by 27
Daanen, H. A. M., & Herweijer, J. (2014) · Building and Environment · doi:10.1016/j.buildenv.2014.04.010 · Cited by 27
Vascular Endothelial Cell Injury Partly Induced by Mesenteric Lymph in Heat Stroke
Tong, H., Wan, P., Zhang, X.-Q., Duan, P.-K., Tang, Y., Chen, Y., Tang, L., & Su, L. (2013) · Inflammation · doi:10.1007/s10753-013-9708-x · Cited by 27
Estimating the Incidence of Heat-Related Deaths Among Immigrants in Pima County, Arizona
Keim, S. M., Mays, M. Z., Parks, B. O., Pytlak, E., Harris, R. B., & Kent, M. A. (2006) · Journal of Immigrant and Minority Health · doi:10.1007/s10903-006-8527-z · Cited by 27
Heat Stroke in Schizophrenia During Clozapine Treatment: Rapid Recognition and Management
Kerwin, R. W., Osborne, S., & Sáinz‐Fuertes, R. (2004) · Journal of Psychopharmacology · doi:10.1177/0269881104040250 · Cited by 27
Onozuka, D., & Hagihara, A. (2015) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2015.11.098 · Cited by 27
Atalay, Ö., Bahadır, S. K., & Kalaoğlu, F. (2015) · Advances in Materials Science and Engineering · doi:10.1155/2015/540394 · Cited by 27
Initial Diagnosis and Management of Coma
Traub, S. J., & Wijdicks, E. F. M. (2016) · Emergency Medicine Clinics of North America · doi:10.1016/j.emc.2016.06.017 · Cited by 27
Michelucci, A., Boncompagni, S., Canato, M., Reggiani, C., & Protasi, F. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/6936897 · Cited by 27
Heart rate variability and plasma nephrines in the evaluation of heat acclimatisation status
Stacey, M. M. J., Delves, S. K., Woods, D. R., Britland, S. E., Macconnachie, L., Allsopp, A. J., Brett, S. J., Fallowfield, J. L., & Boos, C. J. (2017) · European Journal of Applied Physiology · doi:10.1007/s00421-017-3758-y · Cited by 27
Mokoena, K. K., Ethan, C. J., Yu, Y., & Asenso, T. Q. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17239027 · Cited by 29
Soar, J., Perkins, G. D., Abbas, G., Alfonzo, A. V. M., Barelli, A., Bierens, J., Brugger, H., Deakin, C. D., Dunning, J., Georgiou, M., et al. (2010) · Notfall + Rettungsmedizin · doi:10.1007/s10049-010-1374-z · Cited by 24
Passive heat stress reduces circulating endothelial and platelet microparticles
Bain, A. R., Ainslie, P. N., Bammert, T. D., Hijmans, J. G., Sekhon, M. S., Hoiland, R. L., Flück, D., Donnelly, J., & DeSouza, C. A. (2017) · Experimental Physiology · doi:10.1113/ep086336 · Cited by 26
The Role of Ecosystem Services in Community Well-Being
Summers, J. K., Smith, L. M., Fulford, R. S., & Crespo, R. D. J. (2018) · InTech eBooks · doi:10.5772/intechopen.74068 · Cited by 29
Evidence for temperature‐mediated regional increases in cerebral blood flow during exercise
Caldwell, H. G., Coombs, G. B., Howe, C. A., Hoiland, R. L., Patrician, A., Lucas, S. J. E., & Ainslie, P. N. (2020) · The Journal of Physiology · doi:10.1113/jp278827 · Cited by 26
A novel mouse model of heatstroke accounting for ambient temperature and relative humidity
Miyamoto, K., Suzuki, K., Ohtaki, H., Nakamura, M., Yamaga, H., Yagi, M., Honda, K., Hayashi, M., & Dohi, K. (2021) · Journal of Intensive Care · doi:10.1186/s40560-021-00546-8 · Cited by 28
Yoneyama, K., Nakai, M., Higuma, T., TERAMOTO, K., Watanabe, M., Kaihara, T., Sumita, Y., Miyamoto, Y., Yasuda, S., Ishibashi, Y., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-90352-x · Cited by 26
Hard Boiled: Alcohol Use as a Risk Factor for MDMA-Induced Hyperthermia: a Systematic Review
van Amsterdam, J., Brunt, T. M., Pierce, M., & van den Brink, W. (2021) · Neurotoxicity Research · doi:10.1007/s12640-021-00416-z · Cited by 27
Zhu, T., Li, X., Wu, X., & Yang, D. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.898145 · Cited by 26
Monitoring heat stroke with a HClO-activatable near-infrared fluorescent probe
Li, S., Yang, K. L., Wang, P., Liu, Y., Cheng, D., & He, L. (2023) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2023.133696 · Cited by 26
Hamaya, H., Hifumi, T., Kawakita, K., Okazaki, T., Kiridume, K., Shinohara, N., Abe, Y., Takano, K., Hagiike, M., & Kuroda, Y. (2014) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2014.05.056 · Cited by 26
Xuan, L. T. T., Egondi, T., Le, N. T., Toàn, Đ. T. T., & Hương, L. T. (2014) · Global Health Action · doi:10.3402/gha.v7.23115 · Cited by 26
Saha, S., Brock, J. W., Vaidyanathan, A., Easterling, D. R., & Luber, G. (2015) · Environmental Health · doi:10.1186/s12940-015-0005-z · Cited by 26
Pre-existing Lipopolysaccharide May Increase the Risk of Heatstroke in Rats
Lin, X., Li, Y., Li, Z., Zou, F., & Lin, M. (2009) · The American Journal of the Medical Sciences · doi:10.1097/maj.0b013e31818b0fa2 · Cited by 26
Richardson, M., & Purssell, E. (2015) · Archives of Disease in Childhood · doi:10.1136/archdischild-2014-307483 · Cited by 26
Lee, K.-L., Niu, K., Lin, M., & Niu, C. (2012) · Journal of the Formosan Medical Association · doi:10.1016/j.jfma.2012.02.017 · Cited by 26
Impact of intensive care on renal function before graft harvest: results of a monocentric study
Blasco, V., Léone, M., Bouvenot, J., Geissler, A., Albanèse, J., & Martin, C. (2007) · Critical Care · doi:10.1186/cc6120 · Cited by 26
Liu, C., Ke, D., Chen, Z., & Lin, M. (2004) · Shock · doi:10.1097/01.shk.0000135287.16417.5a · Cited by 26
O’Connor, F. G. (2025) · Annals of Internal Medicine · doi:10.7326/annals-25-01958 · Cited by 25
Threat of paediatric hyperthermia in an enclosed vehicle: a year-round study
Duzinski, S. V., Barczyk, A. N., Wheeler, T. C., Iyer, S., & Lawson, K. A. (2013) · Injury Prevention · doi:10.1136/injuryprev-2013-040910 · Cited by 25
Essential role of methyl donors in animal productivity
Cronjé, P. B. (2016) · Animal Production Science · doi:10.1071/an15729 · Cited by 25
Spatiotemporal variation in heat-related out-of-hospital cardiac arrest during the summer in Japan
Onozuka, D., & Hagihara, A. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.01.081 · Cited by 25
Bain, A. R., Hoiland, R. L., Donnelly, J., Nowak‐Flück, D., Sekhon, M. S., Tymko, M. M., Greiner, J. J., DeSouza, C. A., & Ainslie, P. N. (2020) · The Journal of Physiology · doi:10.1113/jp278889 · Cited by 25
Liu, Y., Tang, J., He, Y., Jia, G., Liu, G., Tian, G., Chen, X., Cai, J., Kang, B., & Zhao, H. Y. (2021) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-021-00590-2 · Cited by 25
Lai, J., Hui-Chun, W., & Qin, A. (2021) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2020.0213 · Cited by 25
Oghbaei, H., Hosseini, L., Farajdokht, F., Aghsan, S. R., Majdi, A., Sadigh‐Eteghad, S., Shotorbani, S. S., & Mahmoudi, J. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06582-9 · Cited by 25
Future changes of hot extremes in Spain: towards warmer conditions
Lorenzo, M. N., & Alvarez, I. (2022) · Natural Hazards · doi:10.1007/s11069-022-05306-x · Cited by 25
Drug-Induced Hyperthermia Review
Horseman, M. A., Panahi, L., Udeani, G., Tenpas, A., Verduzco, R., Patel, P. H., Bazan, D. Z., Mora, A., Samuel, N. G., Mingle, A.-C., et al. (2022) · Cureus · doi:10.7759/cureus.27278 · Cited by 26
Association between cooling temperature and outcomes of patients with heat stroke
Chen, L., Xu, S., Xiaoling, Y., Zhao, J., Zhang, Y., & Feng, X. (2023) · Internal and Emergency Medicine · doi:10.1007/s11739-023-03291-y · Cited by 25
Kakamu, T., Hidaka, T., Hayakawa, T., Kumagai, T., Jinnouchi, T., Tsuji, M., Nakano, S., Koyama, K., & Fukushima, T. (2015) · Journal of Occupational Health · doi:10.1539/joh.14-0218-oa · Cited by 25
Fink, R., Eržen, I., Medved, S., & Kastelec, D. (2014) · Indoor and Built Environment · doi:10.1177/1420326x13519348 · Cited by 25
Crespo, R. D. J., Lázaro, P. M., & Yee, S. H. (2018) · Wetlands · doi:10.1007/s13157-017-0990-5 · Cited by 25
Number of Heat Wave Deaths by Diagnosis, Sex, Age Groups, and Area, in Slovenia, 2015 vs. 2003
Perčič, S., Kukec, A., Cegnar, T., & Hojs, A. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15010173 · Cited by 25
A novel severity scoring system for dogs with heatstroke
Segev, G., Aroch, I., Savoray, M., Kass, P. H., & Bruchim, Y. (2015) · Journal of Veterinary Emergency and Critical Care · doi:10.1111/vec.12284 · Cited by 25
Shen, K. H., Chang, C. K., Lin, M.-T., & Chang, C. (2008) · European Journal of Applied Physiology · doi:10.1007/s00421-008-0755-1 · Cited by 26
Mota, R., Hernández‐Espinosa, D., Galbis‐Martínez, L., Ordóñez, A., Miñano, A., Parrilla, P., Vicente, V., Corral, J., & Yélamos, J. (2008) · Critical Care Medicine · doi:10.1097/01.ccm.0000299735.43699.e9 · Cited by 25
Hong, J.-Y., Lai, Y.-C., Chang, C.-Y., Chang, S.-C., & Tang, G. (2011) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2011.09.013 · Cited by 25
Distribution and mitogen response of peripheral blood lymphocytes after exertional heat injury
DuBose, D. A., Wenger, C. B., Flinn, S. D., Judy, T. A., Dubovtsev, A., & Morehouse, D. H. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00039.2003 · Cited by 25
Zhang, S., Breitner, S., Stafoggia, M., de'Donato, F. K., Samoli, E., Zafeiratou, S., Katsouyanni, K., Rao, S., Palomares, A. D.-L., Gasparrini, A., et al. (2024) · Environmental Research · doi:10.1016/j.envres.2024.120023 · Cited by 30
Heat Stress‐Mediated Multi‐Organ Injury: Pathophysiology and Treatment Strategies
Ding, X., & Gao, B. (2025) · Comprehensive physiology · doi:10.1002/cph4.70012 · Cited by 30
Lissoway, J. B., Lipman, G. S., Grahn, D. A., Cao, V. H., Shaheen, M., Phan, S., Weiss, E. A., & Heller, H. C. (2015) · Wilderness and Environmental Medicine · doi:10.1016/j.wem.2014.11.006 · Cited by 24
The Use of Technology to Protect the Health of Athletes During Sporting Competitions in the Heat
Muñiz-Pardos, B., Sutehall, S., Angeloudis, K., Shurlock, J., & Pitsiladis, Y. P. (2019) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2019.00038 · Cited by 27
McCormick, J. J., King, K. E., Côté, M. D., McManus, M. K., Topshee, S. M., Hsu, H.-S., Fujii, N., & Kenny, G. P. (2020) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2020.102643 · Cited by 25
Kim, S., Kim, S.-Y., Oh, J., Chae, Y., Park, J., Kim, D., & Kim, Y.-M. (2020) · Environmental Analysis Health and Toxicology · doi:10.5620/eaht.2020024 · Cited by 24
Vecellio, D. J., Bardenhagen, E. K., Lerman, B., & Brown, R. D. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111583 · Cited by 24
Ji, J., Gao, J., Wang, C., Ouyang, L., Liu, Z., & Liu, Z. (2021) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2021.00084 · Cited by 24
Walter, E. J., Watt, P., Gibson, O. R., Willmott, A. G. B., Mitchell, D., Moreton, R., & Maxwell, N. (2021) · Physiological Reports · doi:10.14814/phy2.14945 · Cited by 23
Wang, C., Yu, B., Chen, R., Su, L., Wu, M., & Liu, Z. (2021) · Renal Failure · doi:10.1080/0886022x.2021.2008975 · Cited by 25
Metadata
- Authors
- Bouchama, A., & Knochel, J. P.
- Affiliations
- King Faisal Specialist Hospital & Research Centre (SA)
- ORCID
- Bouchama, Abderrezak
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2002-06-20
- Volume
- 346
- Issue
- 25
- Pages
- 1978-1988
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4229653650
- Cited by
- 1,898
- References
- 80
- Citations by year
- 2026: 130 · 2025: 115 · 2024: 97 · 2023: 109 · 2022: 103 · 2021: 106 · 2020: 107 · 2019: 91 · 2018: 91 · 2017: 90 · 2016: 81 · 2015: 100 · 2014: 95 · 2013: 73 · 2012: 67
- FWCI
- 4.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Thermoregulation and physiological responses
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Heat shock proteins research
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Thermal Regulation in Medicine
- Keywords
- heatstroke, pathophysiology, heat shock proteins, cytotoxicity, inflammation, coagulation, tissue damage
- MeSH terms
- Acute-Phase Reaction, Animals, Blood Coagulation, Body Temperature Regulation, Central Nervous System Diseases, Endothelium, Vascular, Fever, Heat-Shock Proteins, Humans, Multiple Organ Failure, Incidence, Cytokines, Heat Stress Disorders, Heat Stroke
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review