Cited by 1,008Thyroid Disorders and TreatmentsThyroid and Parathyroid SurgeryOphthalmology and Eye Disorders

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Antithyroid Drugs

Cooper, David S.·2005·New England Journal of Medicine

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Abstract

Antithyroid drugs, which have been available for more than half a century, are important in the management of hyperthyroidism, particularly in patients with Graves' disease, who have a high response rate. Since the responses of patients vary and these agents have potentially serious side effects, a working knowledge of their complex pharmacology is required. This review article considers recent pharmacologic and clinical data related to the use of these compounds.

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Authors: Cooper, D. S.
Affiliations: Johns Hopkins University (US)
Corresponding author: Cooper, David S.
ORCID: Cooper, David S.
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2005-03-03
Volume: 352
Issue: 9
Pages: 905-917
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmra042972
OpenAlex: W4243225672
Cited by: 1,008
References: 123
Citations by year: 2026: 35 · 2025: 36 · 2024: 51 · 2023: 50 · 2022: 45 · 2021: 52 · 2020: 62 · 2019: 38 · 2018: 62 · 2017: 51 · 2016: 66 · 2015: 51 · 2014: 48 · 2013: 56 · 2012: 49
FWCI: 4.48
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
Health Sciences › Medicine › Ophthalmology › Ophthalmology and Eye Disorders
Keywords: antithyroid drugs, hyperthyroidism, Graves' disease, adverse effects, drug response
MeSH terms: Agranulocytosis, Algorithms, Female, Graves Disease, Humans, Hyperthyroidism, Methimazole, Pregnancy, Pregnancy Complications, Propylthiouracil, Antithyroid Agents, Thyroid Gland, Thyrotoxicosis, Thyroxine, Triiodothyronine

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