Major Depressive Disorder

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391

Translating the Histone Code

Jenuwein, T., & Allis, C. D. (2001) · Science · doi:10.1126/science.1063127 · Cited by 9,756

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120

The Epidemiology of Major Depressive Disorder: Results From the National Comorbidity Survey Replication (NCS-R)

Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., Rush, A. J., Walters, E. E., & Wang, P. S. (2003) · JAMA · doi:10.1001/jama.289.23.3095 · Cited by 7,988

Protective and Damaging Effects of Stress Mediators

McEwen, B. S. (1998) · New England Journal of Medicine · doi:10.1056/nejm199801153380307 · Cited by 6,733

Epigenetic programming by maternal behavior

Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177

Physiology and neurobiology of stress and adaptation: central role of the brain

McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 5,429 · cited 1×

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

Lesch, K.-P., Bengel, D., Heils, A., Sabol, S. Z., Greenberg, B. D., Petri, S., Benjamin, J., Müller, C. R., Hamer, D. H., & Murphy, D. L. (1996) · Science · doi:10.1126/science.274.5292.1527 · Cited by 5,162

Stress and the brain: from adaptation to disease

de Kloet, E. R., Joëls, M., & Holsboer, F. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1683 · Cited by 4,621

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321

Antidepressants: Controversies about their efficacy in depression, their effect on suicidality and their place in a complex psychiatric treatment approach

Möller, H. (2009) · The World Journal of Biological Psychiatry · doi:10.1080/15622970903101665 · Cited by 24

Right and left amygdalae activation in patients with major depression receiving antidepressant treatment, as revealed by fMRI

Chen, Y.-T., Huang, M.-W., Hung, I.-C., Lane, H.-Y., & Hou, C.-J. (2014) · Behavioral and Brain Functions · doi:10.1186/1744-9081-10-36 · Cited by 24

Lithium monotherapy increases ACTH and cortisol response in the DEX/CRH test in unipolar depressed subjects. A study with 30 treatment-naive patients

Bschor, T., Ritter, D., Winkelmann, P., Erbe, S., Uhr, M., Ising, M., & Lewitzka, U. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027613 · Cited by 23

Single-channel EEG-based machine learning method for prescreening major depressive disorder

Wan, Z., Zhang, H., Huang, J., Zhou, H., Yang, J., & Zhong, N. (2019) · International Journal of Information Technology & Decision Making · doi:10.1142/s0219622019500342 · Cited by 24

Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT6 receptors in the dorsal raphe nucleus

Asaoka, N., Nagayasu, K., Nishitani, N., Yamashiro, M., Shirakawa, H., Nakagawa, T., & Kaneko, S. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.03.032 · Cited by 25

Superoxide dismutase overexpression protects against glucocorticoid-induced depressive-like behavioral phenotypes in mice

Uchihara, Y., Tanaka, K., Asano, T., Tamura, F., & Mizushima, T. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.12.085 · Cited by 24

Role of Acid Sphingomyelinase in the Regulation of Social Behavior and Memory

Zoicas, I., Reichel, M., Gulbins, E., & Kornhuber, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162498 · Cited by 24

Multi-Scale and Multi-Region Facial Discriminative Representation for Automatic Depression Level Prediction

Niu, M., Tao, J., & Liu, B. (2021) · IEEE International Conference on Acoustics Speech and Signal Processing · doi:10.1109/icassp39728.2021.9413504 · Cited by 24

Loganin ameliorates depression-like behaviors of mice via modulation of serotoninergic system

Pan, C., Xia, C., Yan, Y., Han, Y., Shi, R., He, J., Wang, Z., Wang, Y., Zhang, W., & Xu, J. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05922-8 · Cited by 24

Post-COVID-19 conditions in Ecuadorian patients: an observational study

González‐Andrade, F. (2021) · The Lancet Regional Health - Americas · doi:10.1016/j.lana.2021.100088 · Cited by 28

Effect of Self-administered Transcranial Direct Stimulation in Patients with Major Depressive Disorder: A Randomized, Single-blinded Clinical Trial

Oh, J., Jang, K., Jeon, S., & Chae, J. (2022) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2022.20.1.87 · Cited by 25

Endoplasmic reticulum stress, autophagy, neuroinflammation, and sigma 1 receptors as contributors to depression and its treatment

Fujii, C., Zorumski, C. F., & Izumi, Y. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.391334 · Cited by 25

Etiology of Depression and Implications on Work Environment

Langlieb, A. M., & DePaulo, J. R. (2008) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e31816fca08 · Cited by 24

Interaction of the BcII glucocorticoid receptor polymorphism and childhood abuse in bulimia nervosa (BN): Relationship to BN and to associated trait manifestations

Steiger, H., Gauvin, L. I., Joober, R., Israël, M., Badawi, G., Groleau, P., Bruce, K. R., Kin, N. M. K. N. Y., Sycz, L., & Ouelette, A. S. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.10.005 · Cited by 24

An estradiol-independent BDNF-NPY cascade is involved in the antidepressant effect of mechanical acupuncture instruments in ovariectomized rats

Seo, S. Y., Moon, J., Kang, S.-Y., Kwon, O. S., Kwon, S., Bang, S. K., Kim, S. P., Choi, K., & Ryu, Y. (2018) · Scientific Reports · doi:10.1038/s41598-018-23824-2 · Cited by 25

Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)

Ren, H., Fabbri, C., Uher, R., Rietschel, M., Mors, O. N., Henigsberg, N., Hauser, J., Zobel, A. W., Maier, W., Dernovšek, M. Z., et al. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0198-3 · Cited by 23

Inhibition of GALR1 in PFC Alleviates Depressive-Like Behaviors in Postpartum Depression Rat Model by Upregulating CREB-BNDF and 5-HT Levels

Li, H., Wang, T., Shi, C., Yang, Y., Li, X., Wu, Y., & Xu, Q. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00588 · Cited by 24

Serum insulin-like growth factor-1 and relaxin-3 are linked with major depressive disorder

Ali, S., Nahar, Z., Rahman, M. R., Islam, S. M. A., Bhuiyan, M. A., & Islam, M. R. (2020) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2020.102164 · Cited by 24

Cognitive Therapy in the Treatment and Prevention of Depression: A Fifty-Year Retrospective with an Evolutionary Coda

Hollon, S. D., DeRubeis, R. J., Andrews, P. W., & Thomson, J. A. (2020) · Cognitive Therapy and Research · doi:10.1007/s10608-020-10132-1 · Cited by 24

Studying Stress in the Twenty-First-Century: An Update of Stress Concepts and Research

Wheaton, B., & Montazer, S. (2017) · Cambridge University Press eBooks · doi:10.1017/9781316471289.013 · Cited by 24

Psychiatry in orthodontics. Part 1: Typical adolescent psychiatric disorders and their relevance to orthodontic practice

Neeley, W. W., Kluemper, G. T., & Hays, L. R. (2006) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2005.11.009 · Cited by 25

Electroconvulsive therapy and nursing care

Kavanagh, A., & McLoughlin, D. M. (2009) · British Journal of Nursing · doi:10.12968/bjon.2009.18.22.45564 · Cited by 24

Deep Brain Stimulation

Slowinski, J. L., Uitti, R. J., Putzke, J. D., & Wharen, R. E. (2007) · Journal of neurosurgery · doi:10.3171/jns.2007.106.1.192 · Cited by 24

The neurodegenerative hypothesis of depression and the influence of antidepressant medications

Hall, S., Parr, B.-A., Hussey, S., Anoopkumar‐Dukie, S., Arora, D. S., & Grant, G. D. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176967 · Cited by 26

Deep learning-based depression recognition through facial expression: A systematic review

Cao, X., Zhai, L., Zhai, P., Li, F., He, T., & He, L. (2025) · Neurocomputing · doi:10.1016/j.neucom.2025.129605 · Cited by 24

Differential co-expression and regulation analyses reveal different mechanisms underlying major depressive disorder and subsyndromal symptomatic depression

Xu, F., Yang, H. J., Chen, J., Wu, Q., Gong, W., Zhang, J., Shao, W., Mu, J., Yang, D., Yang, Y., et al. (2015) · BMC Bioinformatics · doi:10.1186/s12859-015-0543-y · Cited by 23

Inflammatory biomarkers and cognitive functioning in individuals with euthymic bipolar disorder: exploratory study

Strawbridge, R., Carter, R., Saldarini, F., Tsapekos, D., & Young, A. H. (2021) · BJPsych Open · doi:10.1192/bjo.2021.966 · Cited by 23

Resting and TMS-EEG markers of treatment response in major depressive disorder: A systematic review

Strafella, R., Chen, R. E., Rajji, T. K., Blumberger, D. M., & Voineskos, D. (2022) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2022.940759 · Cited by 23

All the brain's a stage for serotonin: the forgotten story of serotonin diffusion across cell membranes

Andrews, P. W., Bosyj, C., Brenton, L., Green, L., Gasser, P. J., Lowry, C. A., & Pickel, V. M. (2022) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2022.1565 · Cited by 24

Neuroimmune modulation by tryptophan derivatives in neurological and inflammatory disorders

Kondo, T., Okada, Y., Saika, S., Yamaguchi, N., Hatakeyama, S., & Maruyama, K. (2024) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2024.151418 · Cited by 24

The H/Rouen mouse model displays depression-like and anxiety-like behaviors

Yacoubi, M. E., Rappeneau, V., Champion, E., Malleret, G., & Vaugeois, J. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.07.048 · Cited by 22

ErbB3 mRNA leukocyte levels as a biomarker for major depressive disorder

Milanesi, E., Minelli, A., Cattane, N., Cattaneo, A., Mora, C., Barbon, A., Mallei, A., Popoli, M., Florio, V., Conca, A., et al. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-145 · Cited by 23

The Relation of Co-occurring Musculoskeletal Pain and Depressive Symptoms With Work Ability

Shiri, R., Kaila‐Kangas, L., Ahola, K., Kivekäs, T., Viikari-Juntura, E. R. A., Heliövaara, M., Miranda, H., & Leino‐Arjas, P. (2013) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e3182a4ffc4 · Cited by 23

Blood oxygen level-dependent signals via fMRI in the mood-regulating circuit using two animal models of depression are reversed by chronic escitalopram treatment

Hui, J., Xi, G., Liu, S., Li, X.-L., Geng, L., Teng, G., Nie, B., Shan, B., Yan, J., Dong, L., et al. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.05.044 · Cited by 23

Is plasminogen activator inhibitor‐1 a physiological bottleneck bridging major depressive disorder and cardiovascular disease?

Savoy, C. D., Lieshout, R. J. V., & Steiner, M. S. (2016) · Acta Physiologica · doi:10.1111/apha.12726 · Cited by 24

Association between depressive disorders and risk of breast cancer recurrence after curative surgery

Chen, S.-J., Chang, C.-H., Chen, K.-C., & Liu, C. (2016) · Medicine · doi:10.1097/md.0000000000004547 · Cited by 22

What Do Men Want from a Health Screening Mobile App? A Qualitative Study

Teo, C. H., Ng, C. J., & White, A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0169435 · Cited by 23

Predictors of depressive symptoms in emerging adulthood in a low-income urban cohort

Mondi, C. F., Reynolds, A. J., & Ou, S. (2017) · Journal of Applied Developmental Psychology · doi:10.1016/j.appdev.2017.03.009 · Cited by 26

Epinephrine increases malignancy of breast cancer through p38 MAPK signaling pathway in depressive disorders.

Ouyang, X., Zhu, Z., Yang, C., Wang, L., Ding, G., & Jiang, F. (2019) · Europe PMC (PubMed Central) · Cited by 23

Chronic agomelatine and fluoxetine induce antidepressant-like effects in H/Rouen mice, a genetic mouse model of depression

Yacoubi, M. E., Dubois, M., Gabriel, C., Mocaër, E., & Vaugeois, J. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.08.001 · Cited by 23

Childhood Trauma increases suicidal behaviour in a treatment-resistant depression population: a FACE-DR report

Yrondi, A., Vaiva, G., Walter, M., D Amato, T., Bellivier, F., Bennabi, D., Bougerol, T., Camus, V., Doumy, O., Genty, J.-B., et al. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.12.055 · Cited by 21

Modeling of the hypothalamic-pituitary-adrenal axis-mediated interaction between the serotonin regulation pathway and the stress response using a Boolean approximation: a novel study of depression

Moreno-Ramos, O. A., Lattig, M. C., & González Barrios, A. F. (2013) · Theoretical Biology and Medical Modelling · doi:10.1186/1742-4682-10-59 · Cited by 22

Investigating Sex Differences in Classification of Five Emotions from EEG and Eye Movement Signals

Bao, L.-Q., Qiu, J.-L., Tang, H., Zheng, W.-L., & Lu, B.-L. (2019) · 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2019.8857476 · Cited by 22

Molecular biology of serotonergic systems in avian brains

Fujita, T., Aoki, N., Mori, C., Homma, K. J., & Yamaguchi, S. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1226645 · Cited by 22

Depression, anxiety and self-esteem in adolescent girls with polycystic ovary syndrome: a systematic review and meta-analysis

Li, Y., Zhang, J., Zheng, X., Lu, W., Guo, J., Chen, F., & Liu, C. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1399580 · Cited by 31

Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation

Setoyama, D., Yoshino, A., Takamura, M., Okada, G., Iwata, M., Tsunetomi, K., Ohgidani, M., Kuwano, N., Yoshimoto, J., Okamoto, Y., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.09.118 · Cited by 23

An in vitro screening method for probiotics with antidepressant-like effect using the enterochromaffin cell model

Tian, P., Zhu, H., Zou, R., Kong, Q., Xu, M., Zhao, J., Zhang, H., Chen, W., & Wang, G. (2021) · Food & Function · doi:10.1039/d0fo02307h · Cited by 22

mRNA Expression of SMPD1 Encoding Acid Sphingomyelinase Decreases upon Antidepressant Treatment

Rhein, C., Zoicas, I., Marx, L. M., Zeitler, S., Hepp, T., von Zimmermann, C., Mühle, C., Richter‐Schmidinger, T., Lenz, B., Erim, Y., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115700 · Cited by 22

Functional connectivity between the habenula and default mode network and its association with the antidepressant effect of ketamine

Wang, M., Chen, X., Hu, Y., Zhou, Y., Wang, C., Zheng, W., Liu, W., Lan, X., Ning, Y., & Zhang, B. (2021) · Depression and Anxiety · doi:10.1002/da.23238 · Cited by 21

A facial depression recognition method based on hybrid multi-head cross attention network

Li, Y., Liu, Z., Zhou, L., Yuan, X., Shangguan, Z., Hu, X., & Hu, B. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1188434 · Cited by 22

Possible involvement of nitric oxide in antidepressant-like effect of silymarin in male mice

Khoshnoodi, M., Fakhraei, N., & Dehpour, A. R. (2014) · Pharmaceutical Biology · doi:10.3109/13880209.2014.942787 · Cited by 22

The Effects of LPM570065, a Novel Triple Reuptake Inhibitor, on Extracellular Serotonin, Dopamine and Norepinephrine Levels in Rats

Renyu, Z., Li, X., Shi, Y., Shao, Y., Sun, K., Wang, A., Sun, F., Liu, W., Wang, D., Jin, J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091775 · Cited by 23

Lack of influence of rs4680 (COMT) and rs6276 (DRD2) on diagnosis and clinical outcomes in patients with major depression

Chiesa, A., Lia, L., Alberti, S., Lee, S.-J., Han, C., Patkar, A. A., Pae, C., & Serretti, A. (2014) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651501.2014.894073 · Cited by 22

Work ability in sick-listed patients with major depressive disorder

Slebus, F. G., Kuijer, P., Willems, J. H. B. M., Frings‐Dresen, M. H. W., & Sluiter, J. K. (2008) · Occupational Medicine · doi:10.1093/occmed/kqn091 · Cited by 22

Lower cortical serotonin 2A receptors in major depressive disorder, suicide and in rats after administration of imipramine

Dean, B., Tawadros, N., Seo, M. S., Jeon, W. J., Everall, I., Scarr, E., & Gibbons, A. S. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713001648 · Cited by 22

Efficacy of vitamin D supplementation in depression in adults: a systematic review protocol

Li, G., Mbuagbaw, L. C. E., Samaan, Z., Zhang, S., Adachi, J. D., Παπαϊωάννου, Α., & Thabane, L. (2013) · Systematic Reviews · doi:10.1186/2046-4053-2-64 · Cited by 21

Microarray Analysis of the Major Depressive Disorder mRNA Profile Data

Gao, L., Gao, Y., Xu, E., & Xie, J. M. (2015) · Psychiatry Investigation · doi:10.4306/pi.2015.12.3.388 · Cited by 23

Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression

Poretti, M. B., Sawant, R. S., Rask‐Andersen, M., de Cúneo, M. F., Schiöth, H. B., Pérez, M. F., & Carlini, V. P. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4187-4 · Cited by 22

Behavioural alterations are independent of sickness behaviour in chronic experimental Chagas disease

Vilar-Pereira, G., Ruivo, L. A. D. S., & Lannes-Vieira, J. (2015) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/0074-02760150300 · Cited by 23

Possible antidepressant effects of vanillin against experimentally induced chronic mild stress in rats

Abo‐Youssef, A. M. (2016) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1016/j.bjbas.2016.04.003 · Cited by 22

Neuroendocrine Abnormalities in Major Depression: An Insight Into Glucocorticoids, Cytokines, and the Kynurenine Pathway

Nikkheslat, N., Pariante, C. M., & Zunszain, P. A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-811073-7.00003-9 · Cited by 23

Diffusional kurtosis imaging and white matter microstructure modeling in a clinical study of major depressive disorder

Kamiya, K., Okada, N., Sawada, K., Watanabe, Y., Irie, R., Hanaoka, S., Suzuki, Y., Koike, S., Mori, H., Kunimatsu, A., et al. (2018) · NMR in Biomedicine · doi:10.1002/nbm.3938 · Cited by 22

Efficacy of trial-based cognitive therapy, behavioral activation and treatment as usual in the treatment of major depressive disorder: preliminary findings from a randomized clinical trial

Hemanny, C., Carvalho, C., de Vasconcelos, N. S. S. M., Reis, D. M. L., Botelho, A. C., Bonavides, D., Seixas, C., & de Oliveira, I. R. (2019) · CNS Spectrums · doi:10.1017/s1092852919001457 · Cited by 22

Good, better, best: clinical scenarios for the use of L-methylfolate in patients with MDD

Jain, R., Manning, S., & Cutler, A. J. (2019) · CNS Spectrums · doi:10.1017/s1092852919001469 · Cited by 24

Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network

Yazdani, A., Méndez-Giráldez, R., Yazdani, A., Kosorok, M. R., & Roussos, P. (2020) · BMC Bioinformatics · doi:10.1186/s12859-020-03753-6 · Cited by 20

Antidepressant treatment is associated with epigenetic alterations of Homer1 promoter in a mouse model of chronic depression

Sun, L., Verkaik‐Schakel, R. N., Biber, K. P. H., Plösch, T., & Serchov, T. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.10.040 · Cited by 22

Introduction

Dobson, K. S., & Dozois, D. J. A. (2008) · Elsevier eBooks · doi:10.1016/b978-0-08-045078-0.00001-0 · Cited by 23

Does “Psychological Dysfunction” Mean Anything? A Critical Essay on Pathology Versus Agency

Jacobs, D. H., & Cohen, D. (2009) · Journal of Humanistic Psychology · doi:10.1177/0022167809352008 · Cited by 22

Association of the DIO2 gene single nucleotide polymorphisms with recurrent depressive disorder

Gałecka, E., Talarowska, M. E., Orzechowska, A., Górski, P., Bieńkiewicz, M., & Szemraj, J. (2015) · Acta Biochimica Polonica · doi:10.18388/abp.2015_1002 · Cited by 22

White-matter density abnormalities in depressive patients with and without childhood neglect: a voxel-based morphometry (VBM) analysis

Peng, H., Ning, Y., Zhang, Y., Yang, H., Zhang, L., He, Z., Li, Z., Wang, L., Lu, S., Zhou, J., et al. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.06.048 · Cited by 21

Effect of emotions on learning, memory, and disorders associated with the changes in expression levels: A narrative review

Johnson, J. (2024) · Brain Circulation · doi:10.4103/bc.bc_86_23 · Cited by 27

A Multimodal Artificial Intelligence Model for Depression Severity Detection Based on Audio and Video Signals

Zhang, L., Zhang, S., Zhang, X., & Zhao, Y. (2025) · Electronics · doi:10.3390/electronics14071464 · Cited by 22

Abnormal functional connectivity of habenula in untreated patients with first-episode major depressive disorder

Wu, Z., Wang, C., Ma, Z., Pang, M., Wu, Y., Zhang, N., & Zhong, Y. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.112837 · Cited by 21

Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience

Nagai, Y., Kisaka, Y., Nomura, K., Nishitani, N., Andoh, C., Koda, M., Kawai, H., Seiriki, K., Nagayasu, K., Kasai, A., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112149 · Cited by 21

Integrative omics analysis reveals epigenomic and transcriptomic signatures underlying brain structural deficits in major depressive disorder

Zheng, J., Womer, F. Y., Tang, L., Guo, H., Zhang, X., Tang, Y., & Wang, F. (2024) · Translational Psychiatry · doi:10.1038/s41398-023-02724-8 · Cited by 21

Upregulated mRNA levels of SERT, NET, MAOB, and BDNF in various brain regions of ovariectomized rats exposed to chronic aversive stimuli

Charoenphandhu, N., Nuntapornsak, A., Wongdee, K., Krishnamra, N., & Charoenphandhu, J. (2012) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-012-1527-0 · Cited by 21

Cortistatin modulates the expression and release of corticotrophin releasing hormone in rat brain. Comparison with somatostatin and octreotide

Tringali, G., Greco, M. C., Lisi, L., Pozzoli, G., & Navarra, P. (2012) · Peptides · doi:10.1016/j.peptides.2012.02.004 · Cited by 21

Subcortical biophysical abnormalities in patients with mood disorders

Kumar, A., Yang, S., Ajilore, O., Wu, M., Charlton, R. A., & Lamar, M. (2013) · Molecular Psychiatry · doi:10.1038/mp.2013.84 · Cited by 21

Mitochondrial trafficking in neuropsychiatric diseases

Deheshi, S., Pasqualotto, B. A., & Rintoul, G. L. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.06.015 · Cited by 21

Macrophage-Derived Chemokine: A Putative Marker of Pharmacological Therapy Response in Major Depression?

Milenkovic, V. M., Sarubin, N., Hilbert, S., Baghai, T. C., Stöffler, F., Lima‐Ojeda, J. M., Manook, A., Almeqbaali, K., Wetzel, C. H., Rupprecht, R., et al. (2017) · NeuroImmunoModulation · doi:10.1159/000479739 · Cited by 21

Antidepressant-Like Effects ofVaccinium bracteatumin Chronic Restraint Stress Mice: Functional Actions and Mechanism Explorations

Oh, D.-R., Kim, Y., Choi, E.-J., Jung, M., Oh, K.-N., Hong, J., Bae, D., Kim, K., Kang, H., Kim, J., et al. (2018) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x18500180 · Cited by 21

Neuroimaging genomic studies in major depressive disorder: A systematic review

Zhang, H., Mellor, D. J., & Peng, D. (2018) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12829 · Cited by 23

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T., Gibson, J., Adams, M. J., Johnstone, M., Haley, C., Lawrie, S. M., et al. (2018) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2018.07.006 · Cited by 22

New insights on the role of the retina in diagnostic and therapeutic strategies in major depressive disorder

Cosker, E., Schwan, R., Angioï-Duprez, K., Laprévote, V., & Schwitzer, T. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.03.006 · Cited by 21

Antidepressant-like effect of a selenopropargylic benzamide in mice: involvement of the serotonergic system

Besckow, E. M., Nonemacher, N. T., Garcia, C. S., Espíndola, C. N. D. S., Balbom, É. B., Gritzenco, F., Savegnago, L., Godoi, B., Bortolatto, C. F., & Brüning, C. A. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05600-1 · Cited by 21

Evolutionary theory and the treatment of depression: It is all about the squids and the sea bass

Hollon, S. D., Andrews, P. W., Singla, D. R., Maslej, M. M., & Mulsant, B. H. (2021) · Behaviour Research and Therapy · doi:10.1016/j.brat.2021.103849 · Cited by 22

Neurotransmitters, Receptors, and Second Messengers Galore in 40 Years

Snyder, S. H. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3670-09.2009 · Cited by 21

Factors affecting North Carolina dental hygienists' confidence in providing obesity education and counseling

Kading, C. L. (2019) · PubMed · doi:10.17615/2pq9-xq40 · Cited by 21

Pharmacogenetics of Selective Serotonin Reuptake Inhibitors in Pediatric Depression and Anxiety

Kronenberg, S., Frisch, A., Rotberg, B., Carmel, M., Apter, A., & Weizman, A. (2008) · Pharmacogenomics · doi:10.2217/14622416.9.11.1725 · Cited by 21

Impact of mast cells in depression disorder: inhibitory effect of IL-37 (new frontiers)

Conti, P., Caraffa, A., Ronconi, G., Conti, C. M., Kritas, S. K., Mastrangelo, F., Tettamanti, L., & Theoharides, T. C. (2018) · Immunologic Research · doi:10.1007/s12026-018-9004-9 · Cited by 21

Herbal approaches to system dysfunctions

(2013) · Elsevier eBooks · doi:10.1016/b978-0-443-06992-5.00009-8 · Cited by 22

Clinical depression: an evidence-based integrative complementary medicine treatment model.

Sarris, J. J. (2011) · PubMed · Cited by 20

Learning content‐adaptive feature pooling for facial depression recognition in videos

Zhou, X., Huang, P., Liu, H., & Niu, S. (2019) · Electronics Letters · doi:10.1049/el.2019.0443 · Cited by 20

Antidepressant-like effects of solidagenone on mice with bacterial lipopolysaccharide (LPS)-induced depression

Locateli, G., Alves, B. D. O., Miorando, D., Ernetti, J., Alievi, K., Zilli, G. A. L., Serpa, P. Z., Vecchia, C. A. D., da Silva, L. M., Müller, L. G., et al. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112863 · Cited by 20

A Gut Feeling: The Importance of the Intestinal Microbiota in Psychiatric Disorders

Ochoa‐Repáraz, J., Ramelow, C. C., & Kasper, L. H. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.510113 · Cited by 21

Evaluation of Serum Lysophosphatidic Acid and Lysophosphatidylcholine Levels in Major Depressive Disorder Patients

Riya, S., Sultana, S., Daria, S., Proma, M. A., Bhuiyan, M. A., Haque, M. A., & Islam, M. R. (2020) · Cureus · doi:10.7759/cureus.12388 · Cited by 20

A smartphone-assisted brief online cognitive-behavioral intervention for pregnant women with depression: a study protocol of a randomized controlled trial

Zuccolo, P. F., Xavier, M. O., Matijasevich, A., Polanczyk, G. V., & Fatori, D. (2021) · Trials · doi:10.1186/s13063-021-05179-8 · Cited by 21

Antidepressant-like effects of water extract of Cordyceps militaris (Linn.) Link by modulation of ROCK2/PTEN/Akt signaling in an unpredictable chronic mild stress-induced animal model

Lin, Y., Chen, Y., Lu, K., Huang, Y., Panyod, S., Liu, W.-T., Yang, S., Lu, Y.-S., Chen, M.-H., & Sheen, L. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114194 · Cited by 21

Effects of antidepressant drug therapy with or without physical exercise on inflammatory biomarkers in major depressive disorder: a systematic review and meta-analysis of randomized controlled trials

Fernandes, B. M., Scotti-Muzzi, E., & Soeiro‐de‐Souza, M. G. (2021) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-021-03240-8 · Cited by 23

Untargeted Plasma Metabolomic Profiling in Patients with Major Depressive Disorder Using Ultra-High Performance Liquid Chromatography Coupled with Mass Spectrometry

Homorogan, C., Nitusca, D., Enatescu, V., Schubart, P., Moraru, C., Socaciu, C., & Marian, C. (2021) · Metabolites · doi:10.3390/metabo11070466 · Cited by 19

Guest Editorial / Misafir EditoryalDüşünen Adam The Journal of Psychiatry and Neurological Sciences 2014;27:181-185 DOI: 10.5350/DAJPN20142703001

Gonul, A. S., & Aksoy, B. (2015)

The Biology of Affective Disorders

Sachar, E. J., & Baron, M. (1979) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.02.030179.002445 · Cited by 66

Neurodevelopmental and Neurobiological Aspects of Major Depressive Disorder

Rawdin, B., Lindqvist, D., Bush, N. R., Hamilton, S. P., Boparai, R., Mackin, R. S., Reus, V. I., Mellon, S. H., & Wolkowitz, O. M. (2014) · Oxford University Press eBooks · doi:10.1093/med/9780199937806.003.0004 · Cited by 1

Major depressive disorder: a genetic view

Arango, M. R., Díaz, E. S., Peláez, M. C. V., Marín-Cárdenas, J. S., Sánchez, L. M. M., & González, D. G. (2017) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.15332/s1794-9998.2017.0002.11 · Cited by 2

New insights into the neurobiological mechanisms of major depressive disorders

Fakhoury, M. (2015) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2015.01.005 · Cited by 45