Cited by 5,514Rheumatoid Arthritis Research and TherapiesAutoimmune and Inflammatory Disorders ResearchNatural Compounds in Disease Treatment

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The Pathogenesis of Rheumatoid Arthritis

McInnes, Iain B., Schett, Georg·2011·New England Journal of Medicine

DOI 10.1056/nejmra1004965

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Abstract

The increased understanding of the immune mechanisms of rheumatoid arthritis has led to the development of a considerable number of new therapeutic agents that alter the natural history of the disease and reduce mortality.

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Crossref · 10.1056/nejmra1004965

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Balneotherapy (or spa therapy) for rheumatoid arthritis
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Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model
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Authors: McInnes, I. B., & Schett, G.
Affiliations: University of Glasgow (GB)
Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
ORCID: McInnes, Iain B.
Schett, Georg
Venue: New England Journal of Medicine
Publisher: Massachusetts Medical Society
Published: 2011-12-08
Volume: 365
Issue: 23
Pages: 2205-2219
ISSN: 0028-4793 (ISSN-L)
1533-4406
DOI: 10.1056/nejmra1004965
OpenAlex: W2110826367
Cited by: 5,514
References: 100
Citations by year: 2026: 313 · 2025: 415 · 2024: 439 · 2023: 443 · 2022: 469 · 2021: 493 · 2020: 465 · 2019: 409 · 2018: 399 · 2017: 394 · 2016: 379 · 2015: 300 · 2014: 276 · 2013: 204 · 2012: 111
FWCI: 27.90
Type: journal article
Language: en
Open access: closed
Locations: New England Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
Topics: Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
Health Sciences › Medicine › Hematology › Autoimmune and Inflammatory Disorders Research
Health Sciences › Medicine › Complementary and alternative medicine › Natural Compounds in Disease Treatment
Keywords: rheumatoid arthritis, pathogenesis, immune mechanisms, disease-modifying antirheumatic drugs, mortality reduction
MeSH terms: Arthritis, Rheumatoid, Humans, Antirheumatic Agents, Gene-Environment Interaction

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The Pathogenesis of Rheumatoid Arthritis

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