Mobile DNA in Health and Disease

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

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The origin and behavior of mutable loci in maize

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The impact of retrotransposons on human genome evolution

Cordaux, R., & Batzer, M. A. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2640 · Cited by 1,692

Regulatory activities of transposable elements: from conflicts to benefits

Chuong, E. B., Elde, N. C., & Feschotte, C. (2017) · Nature Reviews Genetics · doi:10.1038/nrg.2016.139 · Cited by 1,489

Genetic Mapping in Human Disease

Altshuler, D., Daly, M. J., & Lander, E. S. (2008) · Science · doi:10.1126/science.1156409 · Cited by 1,452

PIWI-interacting small RNAs: the vanguard of genome defence

Siomi, M. C., Sato, K., Pezic, D., & Aravin, A. A. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3089 · Cited by 1,319

Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

Bourc’his, D., & Bestor, T. H. (2004) · Nature · doi:10.1038/nature02886 · Cited by 1,279

Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: a mechanism for non-LTR retrotransposition

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Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

Feng, Q., Moran, J. V., Kazazian, H. H., & Boeke, J. D. (1996) · Cell · doi:10.1016/s0092-8674(00)81997-2 · Cited by 1,139

Hot L1s account for the bulk of retrotransposition in the human population

Brouha, B., Schustak, J., Badge, R. M., Lutz-Prigge, S., Farley, A. H., Moran, J. V., & Kazazian, H. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0831042100 · Cited by 1,073

LINE-mediated retrotransposition of marked Alu sequences

Dewannieux, M., Esnault, C., & Heidmann, T. (2003) · Nature Genetics · doi:10.1038/ng1223 · Cited by 1,026

High frequency retrotransposition in cultured mammalian cells

Moran, J. V., Holmes, S. E., Naas, T. P., DeBerardinis, R. J., Boeke, J. D., & Kazazian, H. H. (1996) · Cell · doi:10.1016/s0092-8674(00)81998-4 · Cited by 1,022

Regulatory evolution of innate immunity through co-option of endogenous retroviruses

Chuong, E. B., Elde, N. C., & Feschotte, C. (2016) · Science · doi:10.1126/science.aad5497 · Cited by 1,008

Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man

Kazazian, H. H., Wong, C., Youssoufian, H., Scott, A. F., Phillips, D. G., & Antonarakis, S. E. (1988) · Nature · doi:10.1038/332164a0 · Cited by 960

Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition

Muotri, A. R., Chu, V. T., Marchetto, M. C. N., Deng, W., Moran, J. V., & Gage, F. H. (2005) · Nature · doi:10.1038/nature03663 · Cited by 942

Human LINE retrotransposons generate processed pseudogenes

Esnault, C., Maestre, J., & Heidmann, T. (2000) · Nature Genetics · doi:10.1038/74184 · Cited by 835

Ty elements transpose through an RNA intermediate

Boeke, J. D., Garfinkel, D. J., Styles, C. A., & Fink, G. R. (1985) · Cell · doi:10.1016/0092-8674(85)90197-7 · Cited by 822

Accumulation of driver and passenger mutations during tumor progression

Božić, I., Tibor Antal, A., Ohtsuki, H., Carter, H. K., Kim, D., Chen, S., Karchin, R., Kinzler, K. W., Vogelstein, B., & Nowak, M. A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010978107 · Cited by 814

L1 retrotransposition in human neural progenitor cells

Coufal, N. G., Garcia-Perez, J. L., Peng, G. E., Yeo, G. W., Mu, Y., Lovci, M. T., Morell, M., O’Shea, K. S., Moran, J. V., & Gage, F. H. (2009) · Nature · doi:10.1038/nature08248 · Cited by 814

Landscape of Somatic Retrotransposition in Human Cancers

Lee, E., Iskow, R., Yang, L., Gokcumen, O., Haseley, P., Luquette, L. J., Lohr, J. G., Harris, C. C., Ding, L., Wilson, R. K., et al. (2012) · Science · doi:10.1126/science.1222077 · Cited by 762

Somatic retrotransposition alters the genetic landscape of the human brain

Baillie, J. K., Barnett, M. W., Upton, K. R., Gerhardt, D. J., Richmond, T. A., De Sapio, F., Brennan, P. M., Rizzu, P., Smith, S., Fell, M., et al. (2011) · Nature · doi:10.1038/nature10531 · Cited by 684

Roles for retrotransposon insertions in human disease

Hancks, D. C., & Kazazian, H. H. (2016) · Mobile DNA · doi:10.1186/s13100-016-0065-9 · Cited by 670

Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells

Grow, E. J., Flynn, R. A., Chavez, S. L., Bayless, N. L., Wossidlo, M., Wesche, D. J., Martin, L., Ware, C. B., Blish, C. A., Chang, H. Y., et al. (2015) · Nature · doi:10.1038/nature14308 · Cited by 666

Human L1 Retrotransposition: cis Preference versus trans Complementation

Wei, W., Gilbert, N., Ooi, S. L., Lawler, J. F., Ostertag, E. M., Kazazian, H. H., Boeke, J. D., & Moran, J. V. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.4.1429-1439.2001 · Cited by 637

Dynamic interactions between transposable elements and their hosts

Levin, H. L., & Moran, J. V. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3030 · Cited by 621

LINE-1 elements in structural variation and disease

Beck, C. R., Garcia-Perez, J. L., Badge, R. M., & Moran, J. V. (2011) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-082509-141802 · Cited by 615

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

Kaneko, H., Dridi, S., Tarallo, V., Gelfand, B. D., Fowler, B. J., Cho, W. G., Kleinman, M. E., Ponicsan, S. L., Hauswirth, W. W., Chiodo, V. A., et al. (2011) · Nature · doi:10.1038/nature09830 · Cited by 601

HIV-1 Reverse TranscriptionPreprint

Hu, W.-S., & Hughes, S. H. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006882 · Cited by 597

Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer.

Miki, Y., Nishisho, I., Horii, A., Miyoshi, Y., Utsunomiya, J., Kinzler, K. W., Vogelstein, B., & Nakamura, Y. (1992) · PubMed · Cited by 564

Natural mutagenesis of human genomes by endogenous retrotransposons

Iskow, R. C., McCabe, M. T., Mills, R. E., Torene, S., Pittard, W. S., Neuwald, A. F., Van Meir, E. G., Vertino, P. M., & Devine, S. E. (2010) · Cell · doi:10.1016/j.cell.2010.05.020 · Cited by 551

Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain

Evrony, G. D., Cai, X., Lee, E., Hills, L. B., Elhosary, P. C., Lehmann, H. S., Parker, J. J., Atabay, K. D., Gilmore, E. C., Poduri, A., et al. (2012) · Cell · doi:10.1016/j.cell.2012.09.035 · Cited by 548

RAG1 Core and V(D)J Recombination Signal Sequences Were Derived from Transib Transposons

Kapitonov, V. V., & Jurka, J. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030181 · Cited by 521

The impact of L1 retrotransposons on the human genome

Kazazian, H. H., & Moran, J. V. (1998) · Nature Genetics · doi:10.1038/ng0598-19 · Cited by 520

Human L1 element target‐primed reverse transcription in vitro

Cost, G. J., Feng, Q., Jacquier, A., & Boeke, J. D. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf592 · Cited by 519

An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons

Jacobs, F. M. J., Greenberg, D., Nguyen, N., Haeussler, M., Ewing, A. D., Katzman, S., Paten, B., Salama, S. R., & Haussler, D. (2014) · Nature · doi:10.1038/nature13760 · Cited by 506

DNA repair mediated by endonuclease-independent LINE-1 retrotransposition

Morrish, T. A., Gilbert, N., Myers, J. S., Vincent, B. J., Stamato, T. D., Taccioli, G. E., Batzer, M. A., & Moran, J. V. (2002) · Nature Genetics · doi:10.1038/ng898 · Cited by 488

Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes

Han, J. S., Szak, S. T., & Boeke, J. D. (2004) · Nature · doi:10.1038/nature02536 · Cited by 484

Human endogenous retrovirus-K contributes to motor neuron disease

Li, W., Lee, M.-H., Henderson, L., Tyagi, R., Bachani, M., Steiner, J., Campanac, E., Hoffman, D. A., von Geldern, G., Johnson, K., et al. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aac8201 · Cited by 482

Human L1 Retrotransposition Is Associated with Genetic Instability In Vivo

Symer, D. E., Connelly, C. J., Szak, S. T., Caputo, E. M., Cost, G. J., Parmigiani, G., & Boeke, J. D. (2002) · Cell · doi:10.1016/s0092-8674(02)00839-5 · Cited by 479

Genomic Deletions Created upon LINE-1 Retrotransposition

Gilbert, N., Lutz-Prigge, S., & Moran, J. V. (2002) · Cell · doi:10.1016/s0092-8674(02)00828-0 · Cited by 474

Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains

Lehrman, M. A., Schneider, W. J., Südhof, T. C., Brown, M. S., Goldstein, J. L., & Russell, D. W. (1985) · Science · doi:10.1126/science.3155573 · Cited by 456

Isolation of an Active Human Transposable Element

Dombroski, B. A., Mathias, S. L., Nanthakumar, E. J., Scott, A. F., & Kazazian, H. H. (1991) · Science · doi:10.1126/science.1662412 · Cited by 455

Many human L1 elements are capable of retrotransposition

Sassaman, D. M., Dombroski, B. A., Moran, J. V., Kimberland, M. L., Naas, T., DeBerardinis, R. J., Gabriel, A., Swergold, G. D., & Kazazian, H. H. (1997) · Nature Genetics · doi:10.1038/ng0597-37 · Cited by 452

Transposon-mediated rewiring of gene regulatory networks contributed to the evolution of pregnancy in mammals

Lynch, V. J., Leclerc, R. D., May, G. E., & Wagner, G. P. (2011) · Nature Genetics · doi:10.1038/ng.917 · Cited by 434

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Tubio, J. M. C., Li, Y., Ju, Y. S., Martincorena, I., Cooke, S. L., Tojo, M., Gundem, G., Pipinikas, C. P., Zamora, J., Raine, K., et al. (2014) · Science · doi:10.1126/science.1251343 · Cited by 412

Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma

Shukla, R., Upton, K. R., Muñoz-López, M., Gerhardt, D. J., Fisher, M. E., Nguyen, T., Brennan, P. M., Baillie, J. K., Collino, A., Ghisletti, S., et al. (2013) · Cell · doi:10.1016/j.cell.2013.02.032 · Cited by 405

Embryonic stem cells use ZFP809 to silence retroviral DNAs

Wolf, D., & Goff, S. P. (2009) · Nature · doi:10.1038/nature07844 · Cited by 388

L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicismPreprint

Kano, H., Godoy, I., Courtney, C., Vetter, M. R., Gerton, G. L., Ostertag, E. M., & Kazazian, H. H. (2009) · Genes & Development · doi:10.1101/gad.1803909 · Cited by 368

From ancestral infectious retroviruses to bona fide cellular genes: Role of the captured syncytins in placentation

Dupressoir, A., Lavialle, C., & Heidmann, T. (2012) · Placenta · doi:10.1016/j.placenta.2012.05.005 · Cited by 362

Cytoplasmic ribonucleoprotein complexes containing human LINE‐1 protein and RNA.

Hohjoh, H., & Singer, M. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00395.x · Cited by 349

Human Genomic Deletions Mediated by Recombination between Alu Elements

Sen, S. K., Han, K., Wang, J., Lee, J., Wang, H., Callinan, P. A., Dyer, M. D., Cordaux, R., Liang, P., & Batzer, M. A. (2006) · The American Journal of Human Genetics · doi:10.1086/504600 · Cited by 340

The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes

Richardson, S. R., Doucet, A. J., Kopera, H. C., Moldovan, J. B., Garcia-Perez, J. L., & Moran, J. V. (2015) · Microbiology Spectrum · doi:10.1128/microbiolspec.mdna3-0061-2014 · Cited by 338

Increased L1 Retrotransposition in the Neuronal Genome in Schizophrenia

Bundo, M., Toyoshima, M., Okada, Y., Akamatsu, W., Ueda, J., Nemoto-Miyauchi, T., Sunaga, F., Toritsuka, M., Ikawa, D., Kakita, A., et al. (2014) · Neuron · doi:10.1016/j.neuron.2013.10.053 · Cited by 321

Ubiquitous L1 Mosaicism in Hippocampal Neurons

Upton, K. R., Gerhardt, D. J., Jesuadian, J. S., Richardson, S. R., Sánchez-Luque, F. J., Bodea, G. O., Ewing, A. D., Salvador-Palomeque, C., van der Knaap, M. S., Brennan, P. M., et al. (2015) · Cell · doi:10.1016/j.cell.2015.03.026 · Cited by 320

High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomesPreprint

Ewing, A. D., & Kazazian, H. H. (2010) · Genome Research · doi:10.1101/gr.106419.110 · Cited by 318

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancerPreprint

Scott, E., Gardner, E. J., Masood, A., Chuang, N. T., Vertino, P. M., & Devine, S. E. (2016) · Genome Research · doi:10.1101/gr.201814.115 · Cited by 317

Multiple Fates of L1 Retrotransposition Intermediates in Cultured Human Cells

Gilbert, N., Lutz, S., Morrish, T. A., & Moran, J. V. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.17.7780-7795.2005 · Cited by 293

LINE-1 ORF1 Protein Localizes in Stress Granules with Other RNA-Binding Proteins, Including Components of RNA Interference RNA-Induced Silencing Complex

Goodier, J. L., Zhang, L., Vetter, M. R., & Kazazian, H. H. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00332-07 · Cited by 292

Cis-preferential LINE-1 reverse transcriptase activity in ribonucleoprotein particles

Kulpa, D. A., & Moran, J. V. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1107 · Cited by 291

Extensive somatic L1 retrotransposition in colorectal tumorsPreprint

Sólyom, S., Ewing, A. D., Rahrmann, E. P., Doucet-O’Hare, T. T., Nelson, H. H., Burns, M. B., Harris, R. S., Sigmon, D. F., Casella, A. M., Avigdor, B. E., et al. (2012) · Genome Research · doi:10.1101/gr.145235.112 · Cited by 275

RNA truncation by premature polyadenylation attenuates human mobile element activity

Belancio, V. P., & Deininger, P. L. (2003) · Nature Genetics · doi:10.1038/ng1269 · Cited by 263

Twin Priming: A Proposed Mechanism for the Creation of Inversions in L1 RetrotranspositionPreprint

Ostertag, E. M., & Kazazian, H. H. (2001) · Genome Research · doi:10.1101/gr.205701 · Cited by 255

Mammalian Endogenous Retroviruses

Mager, D. L., & Stoye, J. P. (2015) · Microbiology Spectrum · doi:10.1128/microbiolspec.mdna3-0009-2014 · Cited by 245

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing

Helman, E., Lawrence, M. S., Stewart, C., Sougnez, C., Getz, G., & Meyerson, M. (2014) · Genome Research · doi:10.1101/gr.163659.113 · Cited by 240

Characterization of LINE-1 Ribonucleoprotein Particles

Doucet, A. J., Hulme, A. E., Sahinovic, E., Kulpa, D. A., Moldovan, J. B., Kopera, H. C., Athanikar, J. N., Hasnaoui, M., Bucheton, A., Moran, J. V., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001150 · Cited by 239

The non-autonomous retrotransposon SVA is trans -mobilized by the human LINE-1 protein machinery

Raiz, J., Damert, A., Chira, S., Held, U., Jung‐Klawitter, S., Hamdorf, M., Löwer, J., Strätling, W. H., Löwer, R., & Schumann, G. G. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr863 · Cited by 235

LINE-1 retrotransposition in human embryonic stem cells

Garcia-Perez, J. L., Marchetto, M. C., Muotri, A. R., Coufal, N. G., Gage, F. H., O’Shea, K. S., & Moran, J. V. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm105 · Cited by 235

Discovery of an Active RAG Transposon Illuminates the Origins of V(D)J Recombination

Huang, S., Tao, X., Yuan, S., Zhang, Y., Li, P., Beilinson, H. A., Zhang, Y., Yu, W., Pontarotti, P., Escrivá, H., et al. (2016) · Cell · doi:10.1016/j.cell.2016.05.032 · Cited by 213

A mobile threat to genome stability: The impact of non-LTR retrotransposons upon the human genome

Konkel, M. K., & Batzer, M. A. (2010) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2010.03.001 · Cited by 202

Defining the beginning and end of KpnI family segments.

Grimaldi, G., Skowroński, J., & Singer, M. (1984) · The EMBO Journal · doi:10.1002/j.1460-2075.1984.tb02042.x · Cited by 196

The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retrovirusesPreprint

Wolf, G., Yang, P., Füchtbauer, A. C., Füchtbauer, E., Silva, A. M., Park, C., Wu, W., Nielsen, A. L., Pedersen, F. S., & Macfarlan, T. S. (2015) · Genes & Development · doi:10.1101/gad.252767.114 · Cited by 196

L1 retrotransposition can occur early in human embryonic development

van den Hurk, J. A. J. M., Meij, I. C., del Carmen Seleme, M., Kano, H., Nikopoulos, K., Hoefsloot, L. H., Sistermans, E. A., de Wijs, I. J., Mukhopadhyay, A., Plomp, A. S., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm108 · Cited by 193

Retrotransposition of marked SVA elements by human L1s in cultured cells

Hancks, D. C., Goodier, J. L., Mandal, P. K., Cheung, L. E., & Kazazian, H. H. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr245 · Cited by 191

Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy

Taniguchi‐Ikeda, M., Kobayashi, K., Kanagawa, M., Yu, C.-C., Mori, K., Oda, T., Kuga, A., Kurahashi, H., Akman, H. O., DiMauro, S., et al. (2011) · Nature · doi:10.1038/nature10456 · Cited by 189

L1 Retrotransposons and Somatic Mosaicism in the Brain

Richardson, S. R., Morell, S., & Faulkner, G. J. (2014) · Annual Review of Genetics · doi:10.1146/annurev-genet-120213-092412 · Cited by 185

Ribonucleoprotein particle formation is necessary but not sufficient for LINE-1 retrotransposition

Kulpa, D. A., & Moran, J. V. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi354 · Cited by 181

Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres

Morrish, T. A., Garcia-Perez, J. L., Stamato, T. D., Taccioli, G. E., Sekiguchi, J., & Moran, J. V. (2007) · Nature · doi:10.1038/nature05560 · Cited by 178

LINE-1 expression and retrotransposition in Barrett’s esophagus and esophageal carcinoma

Doucet-O’Hare, T. T., Rodić, N., Sharma, R., Darbari, I., Abril, G., Choi, J. A., Ahn, J. Y., Cheng, Y., Anders, R. A., Burns, K. H., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1502474112 · Cited by 158

Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma

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The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition

Moldovan, J. B., & Moran, J. V. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005121 · Cited by 147

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

Goodier, J. L., Pereira, G., Cheung, L. E., Rose, R. J., & Kazazian, H. H. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005252 · Cited by 138

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolutionPreprint

Ewing, A. D., Gacita, A. M., Wood, L. D., Ma, F., Xing, D., Kim, M., Manda, S. S., Abril, G., Pereira, G., Makohon-Moore, A. P., et al. (2015) · Genome Research · doi:10.1101/gr.196238.115 · Cited by 129

Distinct mechanisms for trans-mediated mobilization of cellular RNAs by the LINE-1 reverse transcriptasePreprint

Garcia-Perez, J. L., Doucet, A. J., Bucheton, A., Moran, J. V., & Gilbert, N. (2007) · Genome Research · doi:10.1101/gr.5870107 · Cited by 121

SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation

Hu, S., Li, J., Xu, F., Mei, S., Le Duff, Y., Yin, L., Pang, X., Cen, S., Jin, Q., Liang, C., et al. (2015) · PLOS Genetics · doi:10.1371/journal.pgen.1005367 · Cited by 121

Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family

Wolf, G., Greenberg, D., & Macfarlan, T. S. (2015) · Mobile DNA · doi:10.1186/s13100-015-0050-8 · Cited by 111

The NF1 Gene Contains Hotspots for L1 Endonuclease-Dependent De Novo Insertion

Wimmer, K., Callens, T., Wernstedt, A., & Messiaen, L. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002371 · Cited by 107

A New Family of Chimeric Retrotranscripts Formed by a Full Copy of U6 Small Nuclear RNA Fused to the 3′ Terminus of L1

Buzdin, A. A., Ustyugova, S. V., Gogvadze, E. V., Vinogradova, T. V., Lebedev, Y. B., & Sverdlov, E. D. (2002) · Genomics · doi:10.1006/geno.2002.6843 · Cited by 106

R2 Target-Primed Reverse Transcription: Ordered Cleavage and Polymerization Steps by Protein Subunits Asymmetrically Bound to the Target DNA

Christensen, S. M., & Eickbush, T. H. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.15.6617-6628.2005 · Cited by 91

SVA retrotransposon insertion-associated deletion represents a novel mutational mechanism underlying large genomic copy number changes with non-recurrent breakpoints

Vogt, J. A., Bengesser, K., Claes, K., Wimmer, K., Mautner, V., van Minkelen, R., Legius, E., Brems, H., Upadhyaya, M., Högel, J., et al. (2014) · Genome biology · doi:10.1186/gb-2014-15-6-r80 · Cited by 87

Mobile DNA III

Nicolas, É., Lambin, M., Dandoy, D., Galloy, C., Nguyen, N., Oger, C. A., & Hallet, B. (2015) · ASM Press eBooks · doi:10.1128/9781555819217 · Cited by 83

A large genomic deletion in thePDHX gene caused by the retrotranspositional insertion of a full-length LINE-1 element

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Frequent L1 retrotranspositions originating fromTTC28in colorectal cancer

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