Pharmacologic Treatment of Attention Deficit–Hyperactivity Disorder

ADHD prevalence estimates across three decades: an updated systematic review and meta-regression analysis

Polanczyk, G. V., Willcutt, E. G., Salum, G. A., Kieling, C., & Rohde, L. A. (2014) · International Journal of Epidemiology · doi:10.1093/ije/dyt261 · Cited by 1,822 · see citing works

Attention-deficit/hyperactivity disorder

Faraone, S. V., Asherson, P., Banaschewski, T., Biederman, J., Buitelaar, J. K., Ramos-Quiroga, J. A., Rohde, L. A., Sonuga-Barke, E. J. S., Tannock, R., & Franke, B. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.20 · Cited by 1,479 · see citing works

Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents

Wolraich, M. L., Hagan, J. F., Allan, C., Chan, E., Davison, D., Earls, M., Evans, S. W., Flinn, S. K., Froehlich, T., Frost, J., et al. (2019) · Pediatrics · doi:10.1542/peds.2019-2528 · Cited by 1,410 · see citing works

Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis

Cortese, S., Adamo, N., Del Giovane, C., Mohr-Jensen, C., Hayes, A. J., Carucci, S., Atkinson, L. Z., Tessari, L., Banaschewski, T., Coghill, D., et al. (2018) · The Lancet Psychiatry · doi:10.1016/s2215-0366(18)30269-4 · Cited by 1,402 · see citing works

Meta-analysis of Functional Magnetic Resonance Imaging Studies of Inhibition and Attention in Attention-deficit/Hyperactivity Disorder: Exploring Task-Specific, Stimulant Medication, and Age Effects

Hart, H., Radua, J., Nakao, T., Mataix-Cols, D., & Rubia, K. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.277 · Cited by 764 · see citing works

Brain imaging of the cortex in ADHD: a coordinated analysis of large-scale clinical and population-based samples

Hoogman, M., Muetzel, R., Guimaraes, J. P., Shumskaya, E., Mennes, M., Zwiers, M. P., Jahanshad, N., Sudre, G., Wolfers, T., Earl, E. A., et al. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.18091033 · Cited by 467 · see citing works

Putting the efficacy of psychiatric and general medicine medication into perspective: review of meta-analyses

Leucht, S., Hierl, S., Kissling, W., Dold, M., & Davis, J. M. (2012) · British Journal of Psychiatry · doi:10.1192/bjp.bp.111.096594 · Cited by 451 · see citing works

Practitioner Review: Current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents

Cortese, S., Holtmann, M., Banaschewski, T., Buitelaar, J., Coghill, D., Danckaerts, M., Dittmann, R. W., Graham, J., Taylor, E., Sergeant, J., et al. (2013) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12036 · Cited by 336 · see citing works

Effects of stimulants on brain function in attention-deficit/hyperactivity disorder: a systematic review and meta-analysis

Rubia, K., Alegria, A. A., Cubillo, A. I., Smith, A. B., Brammer, M. J., & Radua, J. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.10.016 · Cited by 315 · see citing works

Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases.

Raman, S. R., Man, K. K. C., Bahmanyar, S., Bérard, A., Bilder, S., Boukhris, T., Bushnell, G., Crystal, S., Furu, K., KaoYang, Y.-H., et al. (2018) · Lancet psychiatry · doi:10.1016/s2215-0366(18)30293-1 · Cited by 285 · see citing works

Task‐related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate

Liddle, E. B., Hollis, C., Batty, M. J., Groom, M. J., Totman, J. J., Liotti, M., Scerif, G., & Liddle, P. F. (2011) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2010.02333.x · Cited by 281 · see citing works

Attention Deficit–Hyperactivity Disorder in Children and Adolescents

Feldman, H. M., & Reiff, M. I. (2014) · New England Journal of Medicine · doi:10.1056/nejmcp1307215 · Cited by 245 · see citing works

Systematic review: nonmedical use of prescription stimulants: risk factors, outcomes, and risk reduction strategies

Faraone, S. V., Rostain, A. L., Montano, C. B., Mason, O., Antshel, K. M., & Newcorn, J. H. (2020) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2019.06.012 · Cited by 225 · see citing works

Risks and benefits of attention-deficit/hyperactivity disorder medication on behavioral and neuropsychiatric outcomes: a qualitative review of pharmacoepidemiology studies using linked prescription databases

Chang, Z., Ghirardi, L., Quinn, P. D., Asherson, P., D’Onofrio, B. M., & Larsson, H. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.04.009 · Cited by 175 · see citing works

Methyiphenidate vs. amphetamine: Comparative review

Arnold, L. E. (2000) · Journal of Attention Disorders · doi:10.1177/108705470000300403 · Cited by 164 · see citing works

Stimulant and non‐stimulant attention deficit/hyperactivity disorder drug use: total population study of trends and discontinuation patterns 2006–2009

Zetterqvist, J., Asherson, P., Halldner, L., Långström, N., & Larsson, H. (2013) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12004 · Cited by 155 · see citing works

Effects of Long-Term Atomoxetine Treatment for Young Children With Attention-Deficit/Hyperactivity Disorder

KRATOCHVIL, C. J., WILENS, T. E., GREENHILL, L. L., GAO, H., BAKER, K. D., FELDMAN, P. D., & GELOWITZ, D. L. (2006) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000222788.34229.68 · Cited by 150 · see citing works

Meta-analysis of increased heart rate and blood pressure associated with CNS stimulant treatment of ADHD in adults

Mick, E. O., McManus, D. D., & Goldberg, R. J. (2012) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2012.06.011 · Cited by 134 · see citing works

Systematic review of quality of life and functional outcomes in randomized placebo-controlled studies of medications for attention-deficit/hyperactivity disorder

Coghill, D., Banaschewski, T., Soutullo, C. A., Cottingham, M. G., & Zuddas, A. (2017) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-017-0986-y · Cited by 130 · see citing works

Growth on stimulant medication; clarifying the confusion: a review

Poulton, A. (2005) · Archives of Disease in Childhood · doi:10.1136/adc.2004.056952 · Cited by 129 · see citing works

Blood Pressure and Heart Rate Over 10 Years in the Multimodal Treatment Study of Children With ADHD

Vitiello, B., Elliott, G. R., Swanson, J. M., Arnold, L. E., Hechtman, L. T., Abikoff, H., Molina, B. S. G., Wells, K., Wigal, T. L., Jensen, P. S., et al. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10111705 · Cited by 106 · see citing works

Continued Benefits of Methylphenidate in ADHD After 2 Years in Clinical Practice: A Randomized Placebo-Controlled Discontinuation Study

Matthijssen, A. M., Dietrich, A., Bierens, M., Deters, R. K., van de Loo-Neus, G. H. H., van den Hoofdakker, B. J., Buitelaar, J. K., & Hoekstra, P. J. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.18111296 · Cited by 81 · see citing works

Association of ADHD medications with the risk of cardiovascular diseases: a meta-analysis

Liu, H., Feng, W., & Zhang, D. (2018) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-018-1217-x · Cited by 72 · see citing works

Trajectories of Growth Associated With Long-Term Stimulant Medication in the Multimodal Treatment Study of Attention-Deficit/Hyperactivity Disorder

Greenhill, L. L., Swanson, J. M., Hechtman, L. T., Waxmonsky, J. G., Arnold, L. E., Molina, B. S. G., Hinshaw, S. P., Jensen, P. S., Abikoff, H., Wigal, T. L., et al. (2019) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2019.06.019 · Cited by 69 · see citing works

Associations of Prescribed ADHD Medication in Pregnancy with Pregnancy-Related and Offspring Outcomes: A Systematic Review

Li, L., Sujan, A. C., Butwicka, A., Chang, Z., Cortese, S., Quinn, P. D., Viktorin, A., Öberg, A. S., D'Onofrio, B. M., & Larsson, H. (2020) · CNS Drugs · doi:10.1007/s40263-020-00728-2 · Cited by 42 · see citing works

Effect of Continuing and Discontinuing Medications on Quality of Life After Symptomatic Remission in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis

Tsujii, N., Okada, T., Usami, M., Kuwabara, H., Fujita, J., Negoro, H., Kawamura, M., Iida, J., & Saito, T. (2020) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.19r13015 · Cited by 31 · see citing works

Attention-deficit/hyperactivity disorder

Faraone, S. V., Bellgrove, M. A., Brikell, I., Cortese, S., Hartman, C. A., Hollis, C., Newcorn, J. H., Philipsen, A., Polanczyk, G. V., Rubia, K., et al. (2024) · Nature Reviews Disease Primers · doi:10.1038/s41572-024-00495-0 · Cited by 355 · see citing works

Attention-Deficit/Hyperactivity Disorder Medications and Long-Term Risk of Cardiovascular Diseases

Zhang, L., Li, L., Andell, P., Garcia‐Argibay, M., Quinn, P. D., D'Onofrio, B. M., Brikell, I., Kuja‐Halkola, R., Lichtenstein, P., Johnell, K., et al. (2023) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2023.4294 · Cited by 158 · see citing works

ADHD Pharmacotherapy and Mortality in Individuals With ADHD

Li, L., Zhu, N., Zhang, L., Kuja‐Halkola, R., D'Onofrio, B. M., Brikell, I., Lichtenstein, P., Cortese, S., Larsson, H., & Chang, Z. (2024) · JAMA · doi:10.1001/jama.2024.0851 · Cited by 131 · see citing works

An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder

da Silva, B. S., Grevet, E. H., Silva, L. C. F., Ramos, J. K. N., Rovaris, D. L., & Bau, C. H. D. (2023) · Discover Mental Health · doi:10.1007/s44192-022-00030-1 · Cited by 125 · see citing works

Attention‐deficit/hyperactivity disorder as a risk factor for cardiovascular diseases: a nationwide population‐based cohort study

Li, L., Chang, Z., Sun, J., Garcia‐Argibay, M., Rietz, E. D., Dobrosavljevic, M., Brikell, I., Jernberg, T., Solmi, M., Cortese, S., et al. (2022) · World Psychiatry · doi:10.1002/wps.21020 · Cited by 110 · see citing works

Associations between dimensions of behaviour, personality traits, and mental-health during the COVID-19 pandemic in the United Kingdom

Hampshire, A., Hellyer, P. J., Soreq, E., Mehta, M. A., Ioannidis, K., Trender, W. R., Grant, J. E., & Chamberlain, S. R. (2021) · Nature Communications · doi:10.1038/s41467-021-24365-5 · Cited by 108 · see citing works

Alcohol use disorders and ADHD.

Luderer, M., Ramos Quiroga, J. A., Faraone, S. V., Zhang-James, Y., & Reif, A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.07.010 · Cited by 102 · see citing works

The dopamine hypothesis for ADHD: An evaluation of evidence accumulated from human studies and animal models

MacDonald, H. J., Kleppe, R., Szigetvari, P. D., & Haavik, J. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1492126 · Cited by 114 · see citing works

ADHD medication discontinuation and persistence across the lifespan: a retrospective observational study using population-based databases

Brikell, I., Yao, H., Li, L., Astrup, A., Gao, L., Gillies, M. B., Xie, T., Zhang‐James, Y., Dalsgaard, S., Engeland, A., et al. (2023) · The Lancet Psychiatry · doi:10.1016/s2215-0366(23)00332-2 · Cited by 96 · see citing works

Half a century of research on Attention-Deficit/Hyperactivity Disorder: A scientometric study

Cortese, S., Sabé, M., Chen, C., Perroud, N. A., & Solmi, M. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104769 · Cited by 93 · see citing works

Computerized cognitive training in attention-deficit/hyperactivity disorder (ADHD): a meta-analysis of randomized controlled trials with blinded and objective outcomes

Westwood, S. J., Parlatini, V., Rubia, K., Cortese, S., Sonuga-Barke, E. J. S., European ADHD Guidelines Group (EAGG), Banaschewski, T., Baeyens, D., Bölte, S., Brandeis, D., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02000-7 · Cited by 90 · see citing works

Comparative efficacy and acceptability of pharmacological, psychological, and neurostimulatory interventions for ADHD in adults: a systematic review and component network meta-analysis

Ostinelli, E. G., Schulze, M., Zangani, C., Farhat, L. C., Tomlinson, A., Giovane, C. D., Chamberlain, S. R., Philipsen, A., Young, S., Cowen, P. J., et al. (2024) · The Lancet Psychiatry · doi:10.1016/s2215-0366(24)00360-2 · Cited by 90 · see citing works

Methylphenidate for attention-deficit/hyperactivity disorder in adults: a narrative review

Jaeschke, R. R., Sujkowska, E., & Sowa-Kućma, M. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05946-0 · Cited by 90 · see citing works

Review of barriers and interventions to promote treatment engagement for pediatric attention deficit hyperactivity disorder care

Baweja, R., Soutullo, C., & Waxmonsky, J. G. (2021) · World Journal of Psychiatry · doi:10.5498/wjp.v11.i12.1206 · Cited by 68 · see citing works

Monoamines: Dopamine, Norepinephrine, and Serotonin, Beyond Modulation, “Switches” That Alter the State of Target Networks

Azizi, S. A. (2020) · The Neuroscientist · doi:10.1177/1073858420974336 · Cited by 76 · see citing works

Attention‐deficit/hyperactivity disorder ( ADHD ) in adults: evidence base, uncertainties and controversies

Cortese, S., Bellgrove, M. A., Brikell, I., Franke, B., Goodman, D. W., Hartman, C. A., Larsson, H., LEVIN, F. R., Ostinelli, E. G., Parlatini, V., et al. (2025) · World Psychiatry · doi:10.1002/wps.21374 · Cited by 88 · see citing works

Molecular Characterisation of the Mechanism of Action of Stimulant Drugs Lisdexamfetamine and Methylphenidate on ADHD Neurobiology: A Review

Quintero, J., Gutiérrez-Casares, J. R., & Álamo, C. (2022) · Neurology and Therapy · doi:10.1007/s40120-022-00392-2 · Cited by 70 · see citing works

Current Pharmacological Treatments for ADHD

Groom, M. J., & Cortese, S. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_330 · Cited by 68 · see citing works

The Mechanism, Clinical Efficacy, Safety, and Dosage Regimen of Atomoxetine for ADHD Therapy in Children: A Narrative Review

Fu, D., Wu, D.-D., Guo, H.-L., Hu, Y.-H., Xia, Y., Ji, X., Fang, W.-R., Li, Y.-M., Xu, J., Chen, F., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.780921 · Cited by 66 · see citing works

ADHD: Restricted Phenotypes Prevalence, Comorbidity, and Polygenic Risk Sensitivity in ABCD Baseline CohortPreprint

Cordova, M., Antovich, D., Ryabinin, P., Neighbor, C., Mooney, M. A., Dieckmann, N. F., Miranda-Domínguez, Ó., Nagel, B. J., Fair, D. A., & Nigg, J. T. (2021) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2022.03.030 · Cited by 65 · see citing works

A Potential Role for Neuroinflammation in ADHD

Vázquez-González, D., Carreón-Trujillo, S., Álvarez‐Arellano, L., Abarca-Merlin, D. M., Domínguez-López, P., Salazar–García, M., & Corona, J. C. (2023) · Advances in experimental medicine and biology · doi:10.1007/978-981-19-7376-5_15 · Cited by 64 · see citing works

Transcranial direct current stimulation (tDCS) combined with cognitive training in adolescent boys with ADHD: a double-blind, randomised, sham-controlled trial

Westwood, S. J., Criaud, M., Lam, S.-L., Lukito, S., Wallace-Hanlon, S., Kowalczyk, O. S., Kostara, A., Mathew, J. P., Agbedjro, D., Wexler, B. E., et al. (2021) · Psychological Medicine · doi:10.1017/s0033291721001859 · Cited by 59 · see citing works

Precision Medicine Care in ADHD: The Case for Neural Excitation and Inhibition

Mamiya, P. C., Arnett, A. B., & Stein, M. A. (2021) · Brain Sciences · doi:10.3390/brainsci11010091 · Cited by 63 · see citing works

Viloxazine in the Management of CNS Disorders: A Historical Overview and Current Status

Findling, R. L., Candler, S. A., Nasser, A. F., Schwabe, S., Yu, C., Garcia-Olivares, J., O’Neal, W., & Newcorn, J. H. (2021) · CNS Drugs · doi:10.1007/s40263-021-00825-w · Cited by 55 · see citing works

ADHD drug treatment and risk of suicidal behaviours, substance misuse, accidental injuries, transport accidents, and criminality: emulation of target trials

Zhang, L., Zhu, N., Sjölander, A., Nourredine, M., Li, L., Garcia‐Argibay, M., Kuja‐Halkola, R., Brikell, I., Lichtenstein, P., D'Onofrio, B. M., et al. (2025) · BMJ · doi:10.1136/bmj-2024-083658 · Cited by 59 · see citing works

Once-Daily SPN-812 200 and 400 mg in the treatment of ADHD in School-aged Children: A Phase III Randomized, Controlled Trial

Nasser, A. F., Liranso, T., Adewole, T., Fry, N., Hull, J. T., Chowdhry, F. A., Busse, G. D., Melyan, Z., Cutler, A. J., Findling, R. L., et al. (2021) · Clinical Therapeutics · doi:10.1016/j.clinthera.2021.01.027 · Cited by 56 · see citing works

The effects of stimulant dose and dosing strategy on treatment outcomes in attention-deficit/hyperactivity disorder in children and adolescents: a meta-analysis

Farhat, L. C., Flores, J. M., Behling, E., Avila-Quintero, V. J., Lombroso, A., Cortese, S., Polanczyk, G. V., & Bloch, M. H. (2022) · Molecular Psychiatry · doi:10.1038/s41380-021-01391-9 · Cited by 54 · see citing works

Systematic Review: Medication Effects on Brain Intrinsic Functional Connectivity in Patients With Attention-Deficit/Hyperactivity Disorder

Pereira-Sánchez, V., Franco, A. R., Vieira, D. L., de Castro‐Manglano, P., Soutullo, C. A., Milham, M. P., & Castellanos, F. X. (2020) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2020.10.013 · Cited by 53 · see citing works

Systematic Review and Meta-Analysis: Effects of Pharmacological Treatment for Attention-Deficit/Hyperactivity Disorder on Quality of Life

Bellato, A., Perrott, N. J., Marzulli, L., Parlatini, V., Coghill, D., & Cortese, S. (2024) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2024.05.023 · Cited by 48 · see citing works

Recent developments in intranasal drug delivery of nanomedicines for the treatment of neuropsychiatric disorders

Kisku, A., Nishad, A., Agrawal, S., Paliwal, R., Datusalia, A. K., Gupta, G., Singh, S. K., Dua, K., & Sulakhiya, K. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1463976 · Cited by 48 · see citing works

Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants

Ferré, S., Belcher, A. M., Bonaventura, J., Quiroz, C., Sánchez‐Soto, M., Casadó-Anguera, V., Cai, N.-S., Moreno, E., Boateng, C. A., Keck, T. M., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1014678 · Cited by 45 · see citing works

ADHD in children and adolescents: Review of current practice of non-pharmacological and behavioural management

Ogundele, M. O., & Ayyash, H. F. (2023) · AIMS Public Health · doi:10.3934/publichealth.2023004 · Cited by 45 · see citing works

Neurofeedback for Attention-Deficit/Hyperactivity Disorder

Westwood, S. J., Aggensteiner, P.-M., Kaiser, A., Nagy, P., Donno, F., Merkl, D., Balia, C., Goujon, A., Bousquet, E., Capodiferro, A. M., et al. (2024) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2024.3702 · Cited by 44 · see citing works

Nonstimulant Medications for Attention-Deficit/Hyperactivity Disorder (ADHD) in Adults: Systematic Review and Meta-Analysis

Radonjić, N. V., Bellato, A., Khoury, N. M., Cortese, S., & Faraone, S. V. (2023) · CNS Drugs · doi:10.1007/s40263-023-01005-8 · Cited by 45 · see citing works

Adult Attention-Deficit/Hyperactivity Disorder and the Risk of Dementia

Levine, S. Z., Rotstein, A., Kodesh, A., Sandin, S., Lee, B. K., Weinstein, G., Beeri, M. S., & Reichenberg, A. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.38088 · Cited by 40 · see citing works

Distance Learning in Children with and without ADHD: A Case-control Study during the COVID-19 Pandemic

Tessarollo, V., Scarpellini, F., Costantino, I., Cartabia, M., Canevini, M. P., & Bonati, M. R. (2021) · Journal of Attention Disorders · doi:10.1177/10870547211027640 · Cited by 40 · see citing works

Sleep EEG microstructure in children and adolescents with attention deficit hyperactivity disorder: a systematic review and meta-analysis.

Biancardi, C., Sesso, G., Masi, G., Faraguna, U., & Sicca, F. (2021) · Sleep · doi:10.1093/sleep/zsab006 · Cited by 31 · see citing works

Assessing undertreatment and overtreatment/misuse of ADHD medications in children and adolescents across continents: A systematic review and meta-analysis

Massuti, R., Maia, C. R. M., Campani, F., Sônego, M. L., Amaro, J., Akutagava‐Martins, G. C., Tessari, L., Polanczyk, G. V., Cortese, S., & Rohde, L. A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.06.001 · Cited by 36 · see citing works

Attention Deficit-Hyperactivity Disorder (ADHD): From Abnormal Behavior to Impairment in Synaptic Plasticity

Ugarte, G., Piña, R., Contreras, D., Godoy, F., Rubio, D., Rozas, C., Zeise, M. L., Vidal, R., Escobar, J., & Morales, B. (2023) · Biology · doi:10.3390/biology12091241 · Cited by 32 · see citing works

A Practical, Evidence-informed Approach to Managing Stimulant-Refractory Attention Deficit Hyperactivity Disorder (ADHD)

Cortese, S., Newcorn, J. H., & Coghill, D. (2021) · CNS Drugs · doi:10.1007/s40263-021-00848-3 · Cited by 35 · see citing works

The effects of stimulant and non-stimulant medications on the autonomic nervous system (ANS) functioning in people with ADHD: A systematic review and meta-analysis

Idrees, I., Bellato, A., Cortese, S., & Groom, M. J. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104968 · Cited by 34 · see citing works

Increased Prescribing of Attention-Deficit/Hyperactivity Disorder Medication and Real-World Outcomes Over Time

Li, L., Coghill, D., Sjölander, A., Yao, H., Zhang, L., Kuja‐Halkola, R., Brikell, I., Lichtenstein, P., D'Onofrio, B. M., Larsson, H., et al. (2025) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2025.1281 · Cited by 33 · see citing works

Benefits and harms of ADHD interventions: umbrella review and platform for shared decision making

Gosling, C. J., Garcia‐Argibay, M., Prisco, M. D., Arrondo, G., Ayrolles, A., Antoun, S., Caparos, S., Catalán, A., Ellul, P., Dobrosavljevic, M., et al. (2025) · BMJ · doi:10.1136/bmj-2025-085875 · Cited by 35 · see citing works

A Longitudinal Study of Resting-State Connectivity and Response to Psychostimulant Treatment in ADHD

Norman, L. J., Sudre, G. P., Bouyssi-Kobar, M., Sharp, W. S., & Shaw, P. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2021.20091342 · Cited by 32 · see citing works

Do Emotion Dysregulation, Alexithymia and Personality Dimensions Explain the Association Between Attention-Deficit/Hyperactivity Disorder and Binge Eating Among Bariatric Surgery Candidates?

Archi, S. E., Brunault, P., Luca, A. D., Cortese, S., Hankard, R., Bourbao-Tournois, C., Ballon, N., Réveillère, C., & Barrault, S. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.745857 · Cited by 33 · see citing works

Efficacy and Safety of Medication for Attention-Deficit Hyperactivity Disorder in Children and Adolescents with Common Comorbidities: A Systematic Review

Tsujii, N., Usami, M., Naya, N., Tsuji, T., Mishima, H., Horie, J., Fujiwara, M., & Iida, J. (2021) · Neurology and Therapy · doi:10.1007/s40120-021-00249-0 · Cited by 36 · see citing works

Efficacy and safety of methylphenidate and behavioural parent training for children aged 3–5 years with attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled, and sham behavioural parent training-controlled trial

Sugaya, L. S., Salum, G. A., Gurgel, W. D. S., de Morais, E. M., Prette, G. D., Pilatti, C. D., Dalmaso, B. B., Leibenluft, E., Rohde, L. A., & Polanczyk, G. V. (2022) · The Lancet Child & Adolescent Health · doi:10.1016/s2352-4642(22)00279-6 · Cited by 32 · see citing works

Evaluating ADHD medication trial representativeness: a Swedish population-based study comparing hypothetically trial-eligible and trial-ineligible individuals

Garcia-Argibay, M., Chang, Z., Brikell, I., Kuja-Halkola, R., D'Onofrio, B. M., Lichtenstein, P., Newcorn, J. H., Faraone, S. V., Larsson, H., & Cortese, S. (2025) · The Lancet Psychiatry · doi:10.1016/s2215-0366(24)00396-1 · Cited by 31 · see citing works

Individualized prediction models in ADHD: a systematic review and meta-regression

de Pablo, G. S., Iniesta, R., Bellato, A., Caye, A., Dobrosavljevic, M., Parlatini, V., Garcia‐Argibay, M., Li, L., Cabras, A., Ali, M. H., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02606-5 · Cited by 27 · see citing works

Suicidal behaviors and attention deficit hyperactivity disorder (ADHD): a cross-sectional study among Chinese medical college students

Shen, Y., Chan, B. S. M., Huang, C., Cui, X., Liu, J., Lu, J., Patel, M. M., Verrico, C. D., Luo, X., & Zhang, X. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03247-6 · Cited by 27 · see citing works

Long-term medication for ADHD and development of cognitive functions in children and adolescents

Johnson, M., Johnels, J. Å., Östlund, S., Cedergren, K., Omanovic, Z., Hjalmarsson, K., Jakobsson, K., Högstedt, J., & Billstedt, E. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.07.055 · Cited by 27 · see citing works

The Effects of Neurofeedback on Executive Functioning in Children With ADHD: A Meta-Analysis

Louthrenoo, O., Boonchooduang, N., Likhitweerawong, N., Charoenkwan, K., & Srisurapanont, M. (2021) · Journal of Attention Disorders · doi:10.1177/10870547211045738 · Cited by 27 · see citing works

Novel non-stimulants rescue hyperactive phenotype in an adgrl3.1 mutant zebrafish model of ADHD

Sveinsdóttir, H. S., Christensen, C., Thorsteinsson, H. S., Lavalou, P., Parker, M. O., Shkumatava, A., Norton, W., Andriambeloson, E., Wagner, S., & Karlsson, K. Æ. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01505-z · Cited by 26 · see citing works

ADHD medications use and risk of mortality and unintentional injuries: a population-based cohort study

Vasiliadis, H., Lunghi, C., Rahme, E., Rochette, L., Gignac, M., Massamba, V. K., Diallo, F. B., Fansi, A. K., Cortese, S., & LESAGE, A. D. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02825-y · Cited by 28 · see citing works

Comparative cardiovascular safety of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis

Farhat, L. C., Lannes, A., Giovane, C. D., Parlatini, V., Garcia‐Argibay, M., Ostinelli, E. G., Tomlinson, A., Chang, Z., Larsson, H., Fava, C., et al. (2025) · The Lancet Psychiatry · doi:10.1016/s2215-0366(25)00062-8 · Cited by 26 · see citing works

Sensitization-based risk for substance abuse in vulnerable individuals with ADHD: Review and re-examination of evidence

Ivanov, I., Bjork, J. M., Blair, J., & Newcorn, J. H. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104575 · Cited by 25 · see citing works

Intentional Discontinuation of Psychostimulants Used to Treat ADHD in Youth: A Review and Analysis

Lohr, W. D., Wanta, J. W., Baker, M., Grudnikoff, E., Morgan, W. S., Chhabra, D., & Lee, T. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.642798 · Cited by 24 · see citing works

Group-based emotion regulation skills training for adults with ADHD: A feasibility study in an outpatient psychiatric setting

Carroll, P., Hirvikoski, T., Lindholm, C., & Thorell, L. B. (2021) · Applied Neuropsychology Adult · doi:10.1080/23279095.2021.1910512 · Cited by 24 · see citing works

Risk and protective factors for cannabis, cocaine, and opioid use disorders: An umbrella review of meta-analyses of observational studies

Solmi, M., Dragioti, E., Croatto, G., Raduà, J., Borgwardt, S., Carvalho, A. F., Demurtas, J., Mosina, A., Kurotschka, P. K., Shin, J. I., et al. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.03.014 · Cited by 22 · see citing works

Treatment patterns among adults with attention-deficit/hyperactivity disorder in the United States: a retrospective claims study

Schein, J. R., Childress, A. C., Adams, J., Cloutier, M., Gagnon‐Sanschagrin, P., Maitland, J., Bungay, R., Guérin, A., & Lefèbvre, P. (2021) · Current Medical Research and Opinion · doi:10.1080/03007995.2021.1968814 · Cited by 22 · see citing works

Methods to Develop an in silico Clinical Trial: Computational Head-to-Head Comparison of Lisdexamfetamine and Methylphenidate

Gutiérrez-Casares, J. R., Quintero, J., Jorba, G., Junet, V., Martínez, V., Pozo-Rubio, T., Oliva, B., Daura, X., Mas, J. M., & Montoto, C. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.741170 · Cited by 22 · see citing works

Meta-analysis: Altered Perceptual Timing Abilities in Attention-Deficit/Hyperactivity Disorder

Marx, I., Cortese, S., Koelch, M., & Häcker, T. (2021) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2021.12.004 · Cited by 24 · see citing works

Neural Markers of Methylphenidate Response in Children With Attention Deficit Hyperactivity Disorder

Arnett, A. B., Rutter, T. M., & Stein, M. A. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.887622 · Cited by 22 · see citing works

Effectiveness of game-based digital intervention for attention-deficit hyperactivity disorder in children and adolescents: a systematic review and meta-analysis using Beard and Wilson’s conceptualization of perception in experiential learning

Lee, H., Lee, S., Hwang, M., & Woo, K. (2025) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-025-02788-5 · Cited by 21 · see citing works

Evidence-based prescribing of medications for ADHD: where are we in 2023?

Cortese, S. (2023) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2023.2169604 · Cited by 22 · see citing works

Setting the Foundations of Developmental Precision Psychiatry for ADHD

Cortese, S. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2021.21050549 · Cited by 21 · see citing works

EasyFlyTracker: A Simple Video Tracking Python Package for Analyzing Adult Drosophila Locomotor and Sleep Activity to Facilitate Revealing the Effect of Psychiatric Drugs

Qu, S., Zhu, Q., Zhou, H., Gao, Y., Wei, Y., Ma, Y., Wang, Z., Sun, X., Zhang, L., Yang, Q., et al. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.809665 · Cited by 21 · see citing works

Why young people stop taking their attention deficit hyperactivity disorder medication: A thematic analysis of interviews with young people

Titheradge, D., Godfrey, J., Eke, H., Price, A., Ford, T. J., & Janssens, A. I. W. A. (2022) · Child Care Health and Development · doi:10.1111/cch.12978 · Cited by 19 · see citing works

Therapeutic Approaches for ADHD by Developmental Stage and Clinical Presentation

Gálvez‐Contreras, A. Y., Cruz, I., Beltrán-Navarro, B., González-Castañeda, R. E., & González-Pérez, Ó. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191912880 · Cited by 22 · see citing works

Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records

Thorsteinsson, H. S., Baukmann, H. A., Sveinsdóttir, H. S., Halldórsdóttir, D. Þ., Grzymala, B., Hillman, C., Rolfe-Tarrant, J., Parker, M. O., Cope, J. L., Ravarani, C. N. J., et al. (2025) · Neuropsychopharmacology · doi:10.1038/s41386-025-02062-x · Cited by 19 · see citing works

The metacontrol hypothesis as diagnostic framework of OCD and ADHD: A dimensional approach based on shared neurobiological vulnerability

Colzato, L. S., Hommel, B., Zhang, W., Roessner, V., & Beste, C. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104677 · Cited by 20 · see citing works

Predicting efficacy of viloxazine extended-release treatment in adults with ADHD using an early change in ADHD symptoms: Machine learning Post Hoc analysis of a phase 3 clinical trial

Faraone, S. V., Goméni, R., Hull, J. T., Chaturvedi, S. A., Busse, G. D., Melyan, Z., O’Neal, W., Rubin, J. S., & Nasser, A. F. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114922 · Cited by 19 · see citing works

Systematic Review and Meta-Analysis: Reporting and Representation of Race/Ethnicity in 310 Randomized Controlled Trials of Attention-Deficit/Hyperactivity Disorder Medications

Riccioni, A., Raduà, J., Ashaye, F. O., Solmi, M., & Cortese, S. (2023) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2023.09.544 · Cited by 19 · see citing works

Utilization of Drugs for Attention-Deficit Hyperactivity Disorder Among Young Patients in China, 2010–2019

Wang, Z., Wu, X., Yu, Z., & Yu, L. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.802489 · Cited by 18 · see citing works

Attention-Deficit/Hyperactivity Disorder Is Associated With Increased Rates of Childhood Infectious Diseases: A Population-Based Case-Control Study

Merzon, E., Israel, A., Ashkenazi, S., Rotem, A., Schneider, T., Faraone, S. V., Biederman, J., Green, I., Golan‐Cohen, A., Vinker, S., et al. (2022) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2022.06.018 · Cited by 18 · see citing works

Practical clinical guidelines and pharmacological treatment for attention-deficit hyperactivity disorder in Asia

Kawabe, K., Horiuchi, F., Matsumoto, Y., Inoue, S., Okazawa, M., Hosokawa, R., Nakachi, K., Soga, J., & Ueno, S. (2024) · Neuropsychopharmacology Reports · doi:10.1002/npr2.12381 · Cited by 17 · see citing works

Immediate and Sustained Effects of Neurofeedback and Working Memory Training on Cognitive Functions in Children and Adolescents with ADHD: A Multi-Arm Pragmatic Randomized Controlled Trial

Hasslinger, J., Jonsson, U., & Bölte, S. (2022) · Journal of Attention Disorders · doi:10.1177/10870547211063645 · Cited by 17 · see citing works

The future of child and adolescent clinical psychopharmacology: A systematic review of phase 2, 3, or 4 randomized controlled trials of pharmacologic agents without regulatory approval or for unapproved indications

Cortese, S., McGinn, K., Højlund, M., Apter, A., Arango, C., Baeza, I., Banaschewski, T., Buitelaar, J. K., Castro‐Fornieles, J., Coghill, D., et al. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105149 · Cited by 18 · see citing works

Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis

Gosling, C. J., Caparos, S., Pinabiaux, C., Schwarzer, G., Rücker, G., Agha, S. S., Alrouh, H., Ambler, A. P., Anderson, P. J., Andiarena, A., et al. (2023) · The Lancet Psychiatry · doi:10.1016/s2215-0366(23)00272-9 · Cited by 18 · see citing works

Treatments in the pipeline for attention-deficit/hyperactivity disorder (ADHD) in adults

Veronesi, G. F., Gabellone, A., Tomlinson, A., Solmi, M., Correll, C. U., & Cortese, S. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105774 · Cited by 20 · see citing works

The Role of the Dopamine Transporter in the Effects of Amphetamine on Sleep and Sleep Architecture in Drosophila

Karam, C. S., Williams, B. L., Jones, S. K., & Javitch, J. A. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03275-4 · Cited by 17 · see citing works

Familial liability to asthma and ADHD: A Swedish national register‐based study

Sun, S., Kuja‐Halkola, R., Chang, Z., Cortese, S., Almqvist, C., & Larsson, H. (2021) · JCPP Advances · doi:10.1002/jcv2.12044 · Cited by 17 · see citing works

Cognitive behavioural group therapy for adolescents with ADHD: a study of satisfaction and feasibility

Andersen, A., Sund, A. M., Thomsen, P., Lydersen, S., Young, S., & Nøvik, T. (2021) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2021.1965212 · Cited by 10 · see citing works

Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions

Fukuyama, K., Nakano, T., Shiroyama, T., & Okada, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084122 · Cited by 16 · see citing works

Remote assessment of ADHD in children and adolescents: recommendations from the European ADHD Guidelines Group following the clinical experience during the COVID-19 pandemic

Santosh, P., Cortese, S., Hollis, C. P., Bölte, S., Daley, D., Coghill, D., Holtmann, M. H., Sonuga-Barke, E. J. S., Buitelaar, J. K., Banaschewski, T., et al. (2023) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-023-02148-1 · Cited by 17 · see citing works

Diagnosis and Treatment of ADHD in the Pediatric Population

Eiland, L. S., & Gildon, B. L. (2024) · The Journal of Pediatric Pharmacology and Therapeutics · doi:10.5863/1551-6776-29.2.107 · Cited by 16 · see citing works

Extended-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults

Boesen, K., Paludan‐Müller, A. S., Gøtzsche, P. C., & Jørgensen, K. J. (2022) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012857.pub2 · Cited by 21 · see citing works

Viloxazine for Attention-Deficit Hyperactivity Disorder: A Systematic Review and Meta-analysis of Randomized Clinical Trials

Singh, A. D., Balasundaram, M. K., & Singh, A. (2022) · Journal of Central Nervous System Disease · doi:10.1177/11795735221092522 · Cited by 16 · see citing works

Efficacy of stimulants for preschool attention‐deficit/hyperactivity disorder: A systematic review and meta‐analysis

Sugaya, L., Farhat, L., Califano, P., & Polanczyk, G. (2023) · JCPP Advances · doi:10.1002/jcv2.12146 · Cited by 16 · see citing works

A meta-analytic review of the impact of ADHD medications on anxiety and depression in children and adolescents

Bryant, A., Schlesinger, H., Sideri, A., Holmes, J., Buitelaar, J. K., & Meiser‐Stedman, R. (2022) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-022-02004-8 · Cited by 16 · see citing works

The association between psychostimulant use in pregnancy and adverse maternal and neonatal outcomes: results from a distributed analysis in two similar jurisdictions

Camacho, X., Zoëga, H., Gomes, T., Schaffer, A. L., Henry, D. A., Pearson, S., Vigod, S. N., & Havard, A. (2022) · International Journal of Epidemiology · doi:10.1093/ije/dyac180 · Cited by 15 · see citing works

The Effect of Meditation-Based Mind-Body Interventions on Symptoms and Executive Function in People With ADHD: A Meta-Analysis of Randomized Controlled Trials

Zhang, Z., Chang, X., Zhang, W., Yang, S., & Zhao, G. (2023) · Journal of Attention Disorders · doi:10.1177/10870547231154897 · Cited by 16 · see citing works

Psychosis with use of amphetamine drugs, methylphenidate and atomoxetine in adolescent and adults

Hamard, J., Rousseau, V., Durrieu, G., Garcia, P., Yrondi, A., Sommet, A., Revet, A., & Montastruc, F. (2024) · BMJ Mental Health · doi:10.1136/bmjment-2023-300876 · Cited by 15 · see citing works

How to Mitigate Risk of Premature Cardiovascular Disease Among Children and Adolescents with Mental Health Conditions

Xu, W., Zimmermann, M., Forkey, H. C., Griffin, J. L., Wilds, C., Morgan, W. S., Byatt, N., & McNeal, C. J. (2022) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-00998-9 · Cited by 15 · see citing works

Randomised controlled trial of the short-term effects of osmotic-release oral system methylphenidate on symptoms and behavioural outcomes in young male prisoners with attention deficit hyperactivity disorder: CIAO-II study

Asherson, P. J., Johansson, L., Holland, R., Bedding, M., Forrester, A., Giannulli, L., Ginsberg, Y., Howitt, S., Kretzschmar, I., Lawrie, S. M., et al. (2022) · The British Journal of Psychiatry · doi:10.1192/bjp.2022.77 · Cited by 16 · see citing works

Contribution of vascular risk factors to the relationship between ADHD symptoms and cognition in adults and seniors

Callahan, B. L., Plamondon, A., Gill, S., & Ismail, Z. (2021) · Scientific Reports · doi:10.1038/s41598-021-03782-y · Cited by 13 · see citing works

Shared and Unique Effects of Long-Term Administration of Methylphenidate and Atomoxetine on Degree Centrality in Medication-Naïve Children With Attention-Deficit/Hyperactive Disorder

Fu, Z., Yuan, J., Pei, X., Zhang, K., Xu, C., Hu, N., Xie, R., Zhao, Y., Wang, Y., Yang, L., et al. (2022) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyac028 · Cited by 14 · see citing works

The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment

Qu, S., Zhou, X., Wang, Z., Yi, W., Zhou, H., Zhang, X., Zhu, Q., Wang, Y., Yang, Q., Jiang, L., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02314-6 · Cited by 14 · see citing works

Goal management training for adults with ADHD – clients’ experiences with a group-based intervention

Nordby, E., Gilje, S., Jensen, D. A., Sørensen, L., & Stige, S. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03114-4 · Cited by 17 · see citing works

Effect of a Multi-Layer, Extended-Release Methylphenidate Formulation (PRC-063) on Sleep in Adults with ADHD: A Randomized, Double-Blind, Forced-Dose, Placebo-Controlled Trial Followed by a 6-month Open-Label Extension

Weiss, M. D., Surman, C. B. H., Khullar, A., He, E., Cataldo, M., & Donnelly, G. A. E. (2021) · CNS Drugs · doi:10.1007/s40263-021-00814-z · Cited by 14 · see citing works

The Pharmacotherapeutics of Methylphenidate and Atomoxetine for the Treatment of Childhood and Adolescent Attention Deficit-Hyperactivity Disorder

Sibbald, C., Sterling, W. J., Bennett, M., McNally, O., & Rogers, K. (2012) · Journal of Healthcare · doi:10.36959/569/451

Tratamiento actual del trastorno por déficit de atención e hiperactividad (TDAH) Actual treatment of attention defi cit hyperactivity disorder (ADHD)

Palomino, D., Guerrero, C. P., & Martín-Calero, J. (2013) · Cited by 1 · see citing works

The efficacy of methylphenidate and atomoxetine forvoiding dysfunction associated with attention deficit hyperactivity disorder

Tajima, D. (2017) · Japanese Society of Child Neurology

Pharmacological management of attention-deficit hyperactivity disorder

Reeves, G. M., & Schweitzer, J. B. (2004) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.5.6.1313 · Cited by 24 · see citing works

Current Pharmacological Treatments for ADHD

Groom, M. J., & Cortese, S. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_330 · Cited by 68 · see citing works