Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

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Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

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RNA-Guided Human Genome Engineering via Cas9

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Mutations affecting segment number and polarity in Drosophila

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One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

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High-Frequency off-Target Mutagenesis Induced by CRISPR-Cas Nucleases in Human Cells

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RNA-programmed genome editing in human cells

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

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An optimized transgenesis system for Drosophila using germ-line-specific φC31 integrases

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A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

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The mutagenic chain reaction: A method for converting heterozygous to homozygous mutations

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Comparison of Cas9 activators in multiple species

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Augmenting CRISPR applications in Drosophila with tRNA-flanked sgRNAs

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A genome-wide resource for the analysis of protein localisation in Drosophila

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RNAi screening comes of age: improved techniques and complementary approaches

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Safeguarding CRISPR-Cas9 gene drives in yeast

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Enhanced Specificity and Efficiency of the CRISPR/Cas9 System with Optimized sgRNA Parameters in Drosophila

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Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

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Scalable and Versatile Genome Editing Using Linear DNAs with Microhomology to Cas9 Sites in Caenorhabditis elegans

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Nuclear domain ‘knock-in’ screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing

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Reducing resistance allele formation in CRISPR gene drive

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Safeguarding gene drive experiments in the laboratory

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CRISPR-TSKO: A Technique for Efficient Mutagenesis in Specific Cell Types, Tissues, or Organs in Arabidopsis

Decaestecker, W., Buono, R. A., Pfeiffer, M. L., Vangheluwe, N., Jourquin, J., Karimi, M., Isterdael, G. V., Beeckman, T., Nowack, M. K., & Jacobs, T. B. (2019) · The Plant Cell · doi:10.1105/tpc.19.00454 · Cited by 248

Distinct combinations of variant ionotropic glutamate receptors mediate thermosensation and hygrosensation in Drosophila

Knecht, Z. A., Silbering, A. F., Ni, L., Klein, M., Budelli, G., Bell, R., Abuin, L., Ferrer, A. J., Samuel, A. D. T., Benton, R. L., et al. (2016) · eLife · doi:10.7554/elife.17879 · Cited by 252

The Ionotropic Receptors IR21a and IR25a mediate cool sensing in Drosophila

Ni, L., Klein, M., Svec, K. V., Budelli, G., Chang, E. C., Ferrer, A. J., Benton, R. L., Samuel, A. D. T., & Garrity, P. (2016) · eLife · doi:10.7554/elife.13254 · Cited by 248

Genome organization controls transcriptional dynamics during development

Batut, P. J., Bing, X., Sisco, Z., Raimundo, J., Levo, M., & Levine, M. (2022) · Science · doi:10.1126/science.abi7178 · Cited by 237

Daisy-chain gene drives for the alteration of local populations

Noble, C., Min, J., Olejarz, J. W., Buchthal, J., Chavez, A., Smidler, A. L., DeBenedictis, E. A., Church, G. M., Nowak, M. A., & Esvelt, K. M. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1716358116 · Cited by 243

Olfactory receptor and circuit evolution promote host specialization

Auer, T. O., Khallaf, M. A., Silbering, A. F., Zappia, G., Ellis, K. E., Álvarez-Ocaña, R., Arguello, J. R., Hansson, B. S., Jefferis, G. S. X. E., Caron, S. J. C., et al. (2020) · Nature · doi:10.1038/s41586-020-2073-7 · Cited by 234

A CRISPR view of developmentPreprint

Harrison, M. M., Jenkins, B., O’Connor-Giles, K. M., & Wildonger, J. (2014) · Genes & Development · doi:10.1101/gad.248252.114 · Cited by 234

CRISPR‐Cas9 Genome Editing in Drosophila

Gratz, S. J., Rubinstein, C. D., Harrison, M. M., Wildonger, J., & O’Connor-Giles, K. M. (2015) · Current Protocols in Molecular Biology · doi:10.1002/0471142727.mb3102s111 · Cited by 214

Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos

Mir, M., Stadler, M. R., Ortiz, S. A., Hannon, C. E., Harrison, M. M., Darzacq, X., & Eisen, M. B. (2018) · eLife · doi:10.7554/elife.40497 · Cited by 207

Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade

Zheng, Y., Wang, W., Liu, B., Deng, H., Uster, E., & Pan, D. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.08.014 · Cited by 217

Interorgan Communication Pathways in Physiology: Focus on Drosophila

Droujinine, I. A., & Perrimon, N. (2016) · Annual Review of Genetics · doi:10.1146/annurev-genet-121415-122024 · Cited by 211

Resistance mutation conserved between insects and mites unravels the benzoylurea insecticide mode of action on chitin biosynthesis

Douris, V., Steinbach, D., Panteleri, R., Livadaras, I., Pickett, J. A., Leeuwen, T. V., Nauen, R., & VONTAS, J. G. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1618258113 · Cited by 213

Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants

Gáliková, M., Diesner, M., Klepsatel, P., Hehlert, P., Xu, Y., Bickmeyer, I., Predel, R., & Kühnlein, R. P. (2015) · Genetics · doi:10.1534/genetics.115.178897 · Cited by 206

Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators

Li, J., Han, S., Li, H., Udeshi, N. D., Svinkina, T., Mani, D. R., Xu, C., Guajardo, R., Xie, Q., Li, T., et al. (2020) · Cell · doi:10.1016/j.cell.2019.12.029 · Cited by 204

Drosophila Lgr3 Couples Organ Growth with Maturation and Ensures Developmental Stability

Colombani, J., Andersen, D. S., Boulan, L., Boone, É., Romero, N. M., Virolle, V., Texada, M. J., & Léopold, P. (2015) · Current Biology · doi:10.1016/j.cub.2015.09.020 · Cited by 200

Panoramix enforces piRNA-dependent cotranscriptional silencing

Yu, Y., Gu, J., Jin, Y., Luo, Y., Preall, J. B., Ma, J., Czech, B., & Hannon, G. J. (2015) · Science · doi:10.1126/science.aab0700 · Cited by 207

Genome editing retraces the evolution of toxin resistance in the monarch butterfly

Karageorgi, M., Groen, S. C., Sumbul, F., Pelaez, J. N., Verster, K. I., Aguilar, J. M., Hastings, A. P., Bernstein, S. L., Matsunaga, T., Astourian, M., et al. (2019) · Nature · doi:10.1038/s41586-019-1610-8 · Cited by 195

Progress and Prospects of CRISPR/Cas Systems in Insects and Other Arthropods

Sun, D., Guo, Z., Liu, Y., & Zhang, Y. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00608 · Cited by 199

Dilp8 requires the neuronal relaxin receptor Lgr3 to couple growth to developmental timing

Garelli, A., Herédia, F., Casimiro, A. P., Macedo, A., Nunes, C., Garcez, M., Dias, A. R. M., Volonté, Y., Uhlmann, T., Caparrós, E., et al. (2015) · Nature Communications · doi:10.1038/ncomms9732 · Cited by 190

A sleep-inducing gene, nemuri , links sleep and immune function in Drosophila

Toda, H., Williams, J. A., Gulledge, M., & Sehgal, A. (2019) · Science · doi:10.1126/science.aat1650 · Cited by 191

Efficient population modification gene-drive rescue system in the malaria mosquito Anopheles stephensi

Adolfi, A., Gantz, V. M., Jasinskiene, N., Lee, H.-F., Hwang, K., Terradas, G., Bulger, E. A., Ramaiah, A., Bennett, J. B., Emerson, J. J., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-19426-0 · Cited by 181

Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, Aedes aegypti

Li, M., Bui, M., Yang, T., Bowman, C. S., White, B. J., & Akbari, O. S. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1711538114 · Cited by 180

Synthetic microbial consortia for biosynthesis and biodegradation: promises and challenges

Che, S., & Men, Y. (2019) · Journal of Industrial Microbiology and Biotechnology · doi:10.1007/s10295-019-02211-4 · Cited by 177

More than one rabbit out of the hat: Radiation, transgenic and symbiont-based approaches for sustainable management of mosquito and tsetse fly populations

Bourtzis, K., Lees, R. S., Hendrichs, J., & Vreysen, M. J. B. (2016) · Acta Tropica · doi:10.1016/j.actatropica.2016.01.009 · Cited by 179

Editing of the urease gene by CRISPR-Cas in the diatom Thalassiosira pseudonana

Hopes, A., Nekrasov, V., Kamoun, S., & Möck, T. (2016) · Plant Methods · doi:10.1186/s13007-016-0148-0 · Cited by 182

Functional validation of cadherin as a receptor of Bt toxin Cry1Ac in Helicoverpa armigera utilizing the CRISPR/Cas9 system

Wang, J., Zhang, H., Wang, H., Zhao, S., Zuo, Y., Yang, Y., & Wu, Y. (2016) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2016.06.008 · Cited by 173

Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

Meng, H., Yamashita, C., Shiba‐Fukushima, K., Inoshita, T., Funayama, M., Sato, S., Hatta, T., Natsume, T., Umitsu, M., Takagi, J., et al. (2017) · Nature Communications · doi:10.1038/ncomms15500 · Cited by 171

Efficient CRISPR-mediated gene targeting and transgene replacement in the beetleTribolium castaneum

Gilles, A. F., Schinko, J. B., & Averof, M. (2015) · Development · doi:10.1242/dev.125054 · Cited by 175

A modular toolbox for gRNA–Cas9 genome engineering in plants based on the GoldenBraid standard

Vázquez‐Vilar, M., Bernabé‐Orts, J. M., Fernández‐del‐Carmen, A., Ziarsolo, P., Blanca, J., Granell, A., & Orzáez, D. (2016) · Plant Methods · doi:10.1186/s13007-016-0101-2 · Cited by 173

An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms

Kanca, O., Zirin, J. D., García‐Marqués, J., Knight, S. M., Yang‐Zhou, D., Amador, G. O., Chung, H.-L., Zuo, Z., Ma, L., He, Y., et al. (2019) · eLife · doi:10.7554/elife.51539 · Cited by 150

Patronin/Shot Cortical Foci Assemble the Noncentrosomal Microtubule Array that Specifies the Drosophila Anterior-Posterior Axis

Nashchekin, D., Fernandes, A. R., & Johnston, D. S. (2016) · Developmental Cell · doi:10.1016/j.devcel.2016.06.010 · Cited by 163

Overcoming evolved resistance to population-suppressing homing-based gene drives

Marshall, J. M., Buchman, A. B., C., H. M. S., & Akbari, O. S. (2017) · Scientific Reports · doi:10.1038/s41598-017-02744-7 · Cited by 161

Exploring the potential of genome editing CRISPR-Cas9 technology

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A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

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Cleave and Rescue, a novel selfish genetic element and general strategy for gene drive

Oberhofer, G., Ivy, T., & Hay, B. A. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1816928116 · Cited by 158

Advances in Engineering the Fly Genome with the CRISPR-Cas System

Bier, E., Harrison, M. M., O’Connor-Giles, K. M., & Wildonger, J. (2018) · Genetics · doi:10.1534/genetics.117.1113 · Cited by 155

Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs

Yin, L., Maddison, L. A., Li, M., Kara, N., LaFave, M. C., Varshney, G. K., Burgess, S. M., Patton, J. G., & Chen, W. (2015) · Genetics · doi:10.1534/genetics.115.176917 · Cited by 160

CRISPR/Cas9 in insects: Applications, best practices and biosafety concerns

Taning, C. N. T., Eynde, B. V., Yu, N., Ma, S., & Smagghe, G. J. (2017) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2017.01.007 · Cited by 158

Aubergine iCLIP Reveals piRNA-Dependent Decay of mRNAs Involved in Germ Cell Development in the Early Embryo

Barckmann, B., Pierson, S., Dufourt, J., Papin, C., Armenise, C., Port, F., Grentzinger, T., Chambeyron, S., Baronian, G., Desvignes, J., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.07.030 · Cited by 142

Chemoreceptor co-expression in Drosophila melanogaster olfactory neurons

Task, D., Lin, C.-C., Vulpe, A., Afify, A., Ballou, S., Brbic, M., Schlegel, P., Raji, J., Jefferis, G. S., Li, H., et al. (2022) · eLife · doi:10.7554/elife.72599 · Cited by 141

Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger

Song, L., Ouedraogo, J., Kolbusz, M. A., Nguyen, T. T. M., & Tsang, A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0202868 · Cited by 139

Glypicans shield the Wnt lipid moiety to enable signalling at a distance

McGough, I. J., Vecchia, L., Bishop, B., Malinauskas, T., Beckett, K., Joshi, D., O’Reilly, N., Siebold, C., Jones, E. Y., & Vincent, J. (2020) · Nature · doi:10.1038/s41586-020-2498-z · Cited by 140

High-Throughput Genome Editing and Phenotyping Facilitated by High Resolution Melting Curve Analysis

Thomas, H. R., Percival, S. M., Yoder, B. K., & Parant, J. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0114632 · Cited by 137

An Insulin-Sensitive Circular RNA that Regulates Lifespan in Drosophila

Weigelt, C. M., Sehgal, R., Tain, L. S., Cheng, J., Eßer, J., Pahl, A., Dieterich, C., Grönke, S., & Partridge, L. (2020) · Molecular Cell · doi:10.1016/j.molcel.2020.06.011 · Cited by 131

In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila

Lin, S., Ewen‐Campen, B., Ni, X., Housden, B. E., & Perrimon, N. (2015) · Genetics · doi:10.1534/genetics.115.181065 · Cited by 136

Large-Scale Transgenic Drosophila Resource Collections for Loss- and Gain-of-Function Studies

Zirin, J. D., Hu, Y., Liu, L., Yang‐Zhou, D., Colbeth, R., Yan, D., Ewen‐Campen, B., Tao, R., Vogt, E., VanNest, S., et al. (2020) · Genetics · doi:10.1534/genetics.119.302964 · Cited by 125

RNA Interference (RNAi) Screening in Drosophila

Heigwer, F., Port, F., & Boutros, M. (2018) · Genetics · doi:10.1534/genetics.117.300077 · Cited by 125

Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs

Champer, S. E., Oh, S. Y., Liu, C., Wen, Z., Clark, A. G., Messer, P. W., & Champer, J. (2020) · Science Advances · doi:10.1126/sciadv.aaz0525 · Cited by 135

A toxin-antidote CRISPR gene drive system for regional population modification

Champer, J., Lee, E., Yang, E., Liu, C., Clark, A. G., & Messer, P. W. (2020) · Nature Communications · doi:10.1038/s41467-020-14960-3 · Cited by 134

Connectomics Analysis Reveals First-, Second-, and Third-Order Thermosensory and Hygrosensory Neurons in the Adult Drosophila Brain

Marin, E. C., Büld, L., Theiss, M., Sarkissian, T., Roberts, R. J. V., Turnbull, R., Tamimi, I. F. M., Pleijzier, M. W., Laursen, W. J., Drummond, N., et al. (2020) · Current Biology · doi:10.1016/j.cub.2020.06.028 · Cited by 121

Homology Directed Knockin of Point Mutations in the Zebrafish tardbp and fus Genes in ALS Using the CRISPR/Cas9 System

Armstrong, G. A. B., Liao, M., You, Z., Lissouba, A., Chen, B. E., & Drapeau, P. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150188 · Cited by 138

A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population

Champer, J., Yang, E., Lee, E., Liu, J., Clark, A. G., & Messer, P. W. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2004373117 · Cited by 130

RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration

Bakthavachalu, B., Huelsmeier, J., Sudhakaran, I. P., Hillebrand, J., Singh, A., Petrauskas, A., Thiagarajan, D., Sankaranarayanan, M., Mizoue, L. S., Anderson, E. N., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.04.032 · Cited by 127

Exploring the Potential of Cell-Free Protein Synthesis for Extending the Abilities of Biological Systems

Khambhati, K., Bhattacharjee, G., Gohil, N., Braddick, D., Kulkarni, V. V., & Singh, V. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00248 · Cited by 127

Drosophila melanogaster Oogenesis: An Overview

McLaughlin, J. M., & Bratu, D. P. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-2851-4_1 · Cited by 125

A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production

ElMaghraby, M. F., Andersen, P. R., Pühringer, F., Hohmann, U., Meixner, K., Lendl, T., Tirián, L., & Brennecke, J. (2019) · Cell · doi:10.1016/j.cell.2019.07.007 · Cited by 123

A Versatile Two-Step CRISPR- and RMCE-Based Strategy for Efficient Genome Engineering in Drosophila

Zhang, X., Koolhaas, W. H., & Schnorrer, F. (2014) · G3 Genes Genomes Genetics · doi:10.1534/g3.114.013979 · Cited by 122

A mutation in the PSST homologue of complex I (NADH:ubiquinone oxidoreductase) from Tetranychus urticae is associated with resistance to METI acaricides

Bajda, S., Dermauw, W., Panteleri, R., Sugimoto, N., Douris, V., Tirry, L., Osakabe, M., VONTAS, J. G., & Leeuwen, T. V. (2016) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2016.11.010 · Cited by 121

An alternative mode of epithelial polarity in the Drosophila midgut

Chen, J., Sayadian, A.-C., Lowe, N., Lovegrove, H. E., & St Johnston, D. (2018) · PLOS Biology · doi:10.1371/journal.pbio.3000041 · Cited by 118

A Peptidergic Circuit Links the Circadian Clock to Locomotor Activity

King, A. N., Barber, A. F., Smith, A. E., Dreyer, A. P., Sitaraman, D., Nitabach, M. N., Cavanaugh, D. J., & Sehgal, A. (2017) · Current Biology · doi:10.1016/j.cub.2017.05.089 · Cited by 123

Efficient CRISPR/Cas9 Plasmids for Rapid and Versatile Genome Editing in Drosophila

Gokcezade, J., Sienski, G., & Duchek, P. (2014) · G3 Genes Genomes Genetics · doi:10.1534/g3.114.014126 · Cited by 116

A CRISPR/Cas9 mediated point mutation in the alpha 6 subunit of the nicotinic acetylcholine receptor confers resistance to spinosad in Drosophila melanogaster

Zimmer, C. T., Garrood, W. T., Puinean, A. M., Manuela, E.-Z., Williamson, M. S., Davies, T. G. E., & Bass, C. (2016) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2016.04.007 · Cited by 114

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

Oberhofer, G., Ivy, T., & Hay, B. A. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1805278115 · Cited by 111

Molecular safeguarding of CRISPR gene drive experiments

Champer, J., Chung, J., Lee, Y. L., Liu, C., Yang, E., Wen, Z., Clark, A. G., & Messer, P. W. (2019) · eLife · doi:10.7554/elife.41439 · Cited by 111

Ankle2, a Target of Zika Virus, Controls Asymmetric Cell Division of Neuroblasts and Uncovers a Novel Microcephaly Pathway

Link, N., Chung, H.-L., Jolly, A., Withers, M. A., Tepe, B., Arenkiel, B. R., Shah, P. S., Krogan, N. J., Aydın, H., Geçkinli, B. B., et al. (2019) · Developmental Cell · doi:10.1016/j.devcel.2019.10.009 · Cited by 108

A versatile toolkit for CRISPR-Cas13-based RNA manipulation in Drosophila

Huynh, N., Depner, N., Larson, R. T., & King‐Jones, K. (2020) · Genome biology · doi:10.1186/s13059-020-02193-y · Cited by 110

Neural Evolution of Context-Dependent Fly Song

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Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster

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Chemoreceptor co-expression in Drosophila melanogaster olfactory neurons.

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Functional genetics for all: engineered nucleases, CRISPR and the gene editing revolution

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Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

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CTCF loss has limited effects on global genome architecture in Drosophila despite critical regulatory functions

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Environmentally sustainable pest control options forDrosophila suzukii

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CRISPR/Cas9-mediated mutagenesis of the white and Sex lethal loci in the invasive pest, Drosophila suzukii

Li, F., & Scott, M. J. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.12.081 · Cited by 103

The dawn of active genetics

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Different Effects of sgRNA Length on CRISPR-mediated Gene Knockout Efficiency

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Doublesex Regulates the Connectivity of a Neural Circuit Controlling Drosophila Male Courtship Song

Shirangi, T. R., Wong, A. M., Truman, J. W., & Stern, D. L. (2016) · Developmental Cell · doi:10.1016/j.devcel.2016.05.012 · Cited by 101

CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans

Au, V., Li-Leger, E., Raymant, G., Flibotte, S., Chen, G., Martin, K., Fernando, L., Doell, C., Rosell, F. I., Wang, S., et al. (2018) · G3 Genes Genomes Genetics · doi:10.1534/g3.118.200778 · Cited by 95

Xio is a component of the Drosophila sex determination pathway and RNA N 6 -methyladenosine methyltransferase complex

Guo, J., Tang, H.-W., Li, J., Perrimon, N., & Yan, D. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1720945115 · Cited by 103

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9

van Tienen, L. M., Mieszczanek, J., Fiedler, M., Rutherford, T. J., & Bienz, M. (2017) · eLife · doi:10.7554/elife.20882 · Cited by 98

Thermosensitive alternative splicing senses and mediates temperature adaptation in Drosophila

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The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress

Kubrak, O. I., Koyama, T., Ahrentløv, N., Jensen, L., Malita, A., Naseem, M. T., Lassen, M., Nagy, S., Texada, M. J., Halberg, K. A., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28268-x · Cited by 109

Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+ signaling in the Drosophila midgut

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Investigation of the contribution of RyR target-site mutations in diamide resistance by CRISPR/Cas9 genome modification in Drosophila

Douris, V., Papapostolou, K. M., Ilias, A., Roditakis, E. N., Kounadi, S., Riga, M., Nauen, R., & VONTAS, J. G. (2017) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2017.06.013 · Cited by 95

Apical stress fibers enable a scaling between cell mechanical response and area in epithelial tissue

López-Gay, J. M., Nunley, H., Spencer, M., di Pietro, F., Guirao, B., Bosveld, F., Markova, O., Gaugué, I., Pelletier, S., Lubensky, D. K., et al. (2020) · Science · doi:10.1126/science.abb2169 · Cited by 91

Precise genome engineering in Drosophila using prime editing

Bosch, J. A., Birchak, G., & Perrimon, N. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2021996118 · Cited by 93

C9orf72 -derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility

Fumagalli, L., Young, F. L., Boeynaems, S., Decker, M. D., Mehta, A. R., Swijsen, A., Fazal, R., Guo, W., Moisse, M., Beckers, J., et al. (2021) · Science Advances · doi:10.1126/sciadv.abg3013 · Cited by 94

Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease

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CRISPR‐Cas9 Genome Editing in Drosophila

Gratz, S. J., Rubinstein, C. D., Harrison, M. M., Wildonger, J., & O’Connor-Giles, K. M. (2015) · Current Protocols in Molecular Biology · doi:10.1002/0471142727.mb3102s111 · Cited by 214

CRISPR-/Cas9-Mediated Precise and Efficient Genome Editing in Drosophila

Nyberg, K. G., & Carthew, R. W. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2541-5_6 · Cited by 7

Upgraded CRISPR/Cas9 tools for tissue-specific mutagenesis in Drosophila

Koreman, G. T., Xu, Y., Hu, Q., Zhang, Z., Allen, S. E., Wolfner, M. F., Wang, B., & Han, C. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2014255118 · Cited by 29

Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in Drosophila

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