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Cited by 535

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

H 2 O 2 -responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay

Open access
Chen, Qian, Liang, Chao, Sun, Xiaoqi, Chen, Jiawen, Yang, Zhijuan, Zhao, He, Feng, Liangzhu, Liu, Zhuang·2017·Proceedings of the National Academy of Sciences
DOI 10.1073/pnas.1701976114
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Abstract

Significance: Hydrogen peroxide is closely associated with many important physiological and pathological events. Herein, we develop a liposomal nanoprobe for in vivo H 2 O 2 -responsive chromogenic assay, which is highly specific and sensitive to H 2 O 2 . Using such a nanoprobe, photoacoustic imaging of H 2 O 2 -related inflammation processes in mice induced by either LPS or bacteria is realized. Meanwhile, such a nanoprobe, by reacting with endogenous H 2 O 2 produced by tumor cells, allows sensitive photoacoustic imaging of early-stage small tumors and orthotopic brain glioma and even enables accurate differentiation of metastatic sentinel lymph nodes from nonmetastatic ones. Furthermore, owing to its H 2 O 2 -responsive near-infrared absorbance, selective photothermal ablation of tumors is also achieved, illustrating the promise of using this nanoproble for tumor theranostics with great specificity.

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Metadata

Authors
Chen, Q., Liang, C., Sun, X., Chen, J., Yang, Z., Zhao, H., Feng, L., & Liu, Z.
Venue
Proceedings of the National Academy of Sciences
Publisher
Proceedings of the National Academy of Sciences
Published
2017-05-08
Volume
114
Issue
21
Pages
5343-5348
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
DOI
10.1073/pnas.1701976114
OpenAlex
W2612371420
Cited by
535
References
3
FWCI
27.35
Type
journal article
Language
en
Open access
bronze
Licence
www.pnas.org/site/misc/userlicense.xhtml (vor, 184 d)
Funders
  • Ministry of Science and Technology of the People's Republic of China (2016YFA0201200)
  • National Natural Science Foundation of China (51525203)

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CoChat. (2026). Citation check: H 2 O 2 -responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay. https://app.cochat.ai/papers/10.1073/pnas.1701976114
The paper
Chen, Q., Liang, C., Sun, X., Chen, J., Yang, Z., Zhao, H., Feng, L., & Liu, Z. (2017). H 2 O 2 -responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1701976114

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.