The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Mechanisms of sampling interstitial fluid from skin using a microneedle patch
Open accessAbstract
Significance: Diagnosis and monitoring of disease is often done by measuring biomarkers found in blood, urine, saliva, and other bodily fluids. Another rich source of biomarkers is the interstitial fluid that surrounds cells and tissues in the body, but difficulty in accessing this fluid has limited its use in research and medicine. Here, we conducted experimental studies coupled with theoretical modeling to design a patch containing microscopic needles that puncture into superficial layers of skin and thereby enable withdrawal of interstitial fluid through micropores in a simple, minimally invasive manner. This patch can help researchers access interstitial fluid to advance discovery of novel biomarkers and enable doctors to use interstitial fluid for possible future diagnosis and monitoring of disease.
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Cites
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Suction Blister Device for Separation of Viable Epidermis from Dermis*
Kiistala, U. (1968) · Journal of Investigative Dermatology · doi:10.1038/jid.1968.15 · Cited by 448
Engineering Microneedle Patches for Vaccination and Drug Delivery to Skin
Prausnitz, M. R. (2017) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-060816-101514 · Cited by 439
Self-citationSkin models for the testing of transdermal drugs
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Teymourian, H., Parrilla, M., Sempionatto, J. R., Montiel, N. F., Barfidokht, A., Van Echelpoel, R., De Wael, K., & Wang, J. (2020) · ACS Sensors · doi:10.1021/acssensors.0c01318 · Cited by 423
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Jin, X., Liu, C., Xu, T., Su, L., & Zhang, X. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112412 · Cited by 399
Teymourian, H., Moonla, C., Tehrani, F., Vargas, E., Aghavali, R., Barfidokht, A., Tangkuaram, T., Mercier, P. P., Dassau, E., & Wang, J. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.9b05109 · Cited by 278
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Metadata
- Authors
- Samant, P. P., & Prausnitz, M. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2018-04-16
- Volume
- 115
- Issue
- 18
- Pages
- 4583-4588
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2799391791
- Cited by
- 363
- References
- 40
- FWCI
- 12.00
- Type
- journal article
- Language
- en
- Open access
- green
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