The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
"Diversomers": an approach to nonpeptide, nonoligomeric chemical diversity.
Open accessAbstract
Solid-phase chemistry, organic synthesis, and an apparatus for multiple, simultaneous synthesis have been combined to generate libraries of organic compounds ("diversomers"). Arrays of compounds were synthesized over two to three steps incorporating chemically diverse building blocks on a polystyrene-based solid support in a multiple, simultaneous manner. The generality of this approach is illustrated by the syntheses of dipeptides, hydantoins, and benzodiazepines.
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Cites
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Searching for Peptide Ligands with an Epitope Library
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Peptoids: a modular approach to drug discovery.
Simon, R. J., Kania, R. S., Zuckermann, R. N., Huebner, V. D., Jewell, D. A., Banville, S., Ng, S., Wang, L., Rosenberg, S., & Marlowe, C. K. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.20.9367 · Cited by 953
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Random Peptide Libraries: a Source of Specific Protein Binding Molecules
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Cited by
Synthesis and Applications of Small Molecule Libraries
Thompson, L. A., & Ellman, J. A. (1996) · Chemical Reviews · doi:10.1021/cr9402081 · Cited by 1,452
The Current Status of Heterocyclic Combinatorial Libraries
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Generating Diverse Skeletons of Small Molecules Combinatorially
Burke, M. D., Berger, E. M., & Schreiber, S. L. (2003) · Science · doi:10.1126/science.1089946 · Cited by 375
Strategy and Tactics in Combinatorial Organic Synthesis. Applications to Drug Discovery
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The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library.
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Metadata
- Authors
- DeWitt, S. H., Kiely, J. S., Stankovic, C. J., Schroeder, M. C., Cody, D. M., & Pavia, M. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1993-08
- Volume
- 90
- Issue
- 15
- Pages
- 6909-6913
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2039492060
- Cited by
- 340
- References
- 7
- FWCI
- 9.62
- Type
- journal article
- Language
- en
- Open access
- green
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- DeWitt, S. H., Kiely, J. S., Stankovic, C. J., Schroeder, M. C., Cody, D. M., & Pavia, M. R. (1993). "Diversomers": an approach to nonpeptide, nonoligomeric chemical diversity. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.90.15.6909
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
