Chronic Nicotine Treatment Up-regulates Human α3β2 but Not α3β4 Acetylcholine Receptors Stably Transfected in Human Embryonic Kidney Cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Hamill, O. P., Marty, A., Neher, E., Sakmann, B., & Sigworth, F. J. (1981) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/bf00656997 · Cited by 18,436

Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

Picciotto, M. R., Zoli, M., Rimondini, R., Léna, C., Marubio, L. M., Pich, E. M., Fuxe, K., & Changeux, J.-P. (1998) · Nature · doi:10.1038/34413 · Cited by 1,320

Presynaptic nicotinic ACh receptors

Wonnacott, S. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10073-4 · Cited by 1,308

The Diversity of Neuronal Nicotinic Acetylcholine Receptors

Sargent, P. B. (1993) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.16.030193.002155 · Cited by 1,052

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

Wada, E., Wada, K., Boulter, J., Deneris, E. S., Heinemann, S., Patrick, J., & Swanson, L. W. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902840212 · Cited by 1,044

Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

McGehee, D. S., & Role, L. W. (1995) · Annual Review of Physiology · doi:10.1146/annurev.ph.57.030195.002513 · Cited by 1,022

Nicotinic Receptors in the Development and Modulation of CNS Synapses

Role, L. W., & Berg, D. K. (1996) · Neuron · doi:10.1016/s0896-6273(00)80134-8 · Cited by 762

Molecular and cellular aspects of nicotine abuse

Dani, J. A., & Heinemann, S. (1996) · Neuron · doi:10.1016/s0896-6273(00)80112-9 · Cited by 605

Pharmacology of Nicotine: Addiction and Therapeutics

Benowitz, N. L. (1996) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.36.040196.003121 · Cited by 589

Evidence that Tobacco Smoking Increases the Density of (−)‐[3H]Nicotine Binding Sites in Human Brain

Benwell, M. E. M., Balfour, D. J. K., & Anderson, J. M. (1988) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1988.tb10600.x · Cited by 551

Desensitization of neuronal nicotinic receptors

Quick, M. W., & Lester, R. A. J. (2002) · Journal of Neurobiology · doi:10.1002/neu.10109 · Cited by 456

Cellular and synaptic mechanisms of nicotine addiction

Mansvelder, H. D., & McGehee, D. S. (2002) · Journal of Neurobiology · doi:10.1002/neu.10148 · Cited by 450

Cue dependency of nicotine self-administration and smoking

Caggiula, A. R., Donny, E. C., White, A. R., Chaudhri, N., Booth, S., Gharib, M. A., Hoffman, A., Perkins, K. A., & Sved, A. F. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00676-1 · Cited by 444

Alternate stoichiometries of α4β2 nicotinic acetylcholine receptors

Nelson, M. E., Kuryatov, A., Choi, C. H., Zhou, Y., & Lindstrom, J. (2003) · Molecular Pharmacology · doi:10.1124/mol.63.2.332 · Cited by 422

Cellular mechanisms of nicotine addiction

Dani, J. A., & De Biasi, M. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00652-9 · Cited by 408

Connections of nicotine to cancer

Grando, S. A. (2014) · Nature reviews. Cancer · doi:10.1038/nrc3725 · Cited by 396

Nicotine-induced upregulation of nicotinic receptors: Underlying mechanisms and relevance to nicotine addiction

Govind, A. P., Vezina, P., & Green, W. N. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.06.011 · Cited by 338

Muscle and neuronal nicotinic acetylcholine receptors

Kalamida, D., Poulas, K. A., Avramopoulou, V., Fostieri, E., Lagoumintzis, G., Lazaridis, K., Sideri, A., Zouridakis, M., & Tzartos, S. J. (2007) · FEBS Journal · doi:10.1111/j.1742-4658.2007.05935.x · Cited by 352

Prenatal nicotine increases pulmonary α7 nicotinic receptor expression and alters fetal lung development in monkeys

Sekhon, H. S., Jia, Y., Raab, R., Kuryatov, A., Pankow, J. F., Whitsett, J. A., Lindstrom, J., & Spindel, E. R. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5232 · Cited by 311

α4β2 Nicotinic Receptors with High and Low Acetylcholine Sensitivity: Pharmacology, Stoichiometry, and Sensitivity to Long-Term Exposure to Nicotine

Moroni, M., Zwart, R., Sher, E., Cassels, B. K., & Bermúdez, I. (2006) · Molecular Pharmacology · doi:10.1124/mol.106.023044 · Cited by 286

Acetylcholine receptors and myasthenia

Lindstrom, J. M. (2000) · Muscle & Nerve · doi:10.1002/(sici)1097-4598(200004)23:4 · Cited by 277

Nicotine acts as a pharmacological chaperone to up-regulate human α4β2 acetylcholine receptors

Kuryatov, A., Luo, J., Cooper, J., & Lindstrom, J. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.012419 · Cited by 275

Nicotine upregulates its own receptors through enhanced intracellular maturation

Sallette, J., Pons, S., Devillers-Thiery, A., Soudant, M., Prado de Carvalho, L., Changeux, J.-P., & Corringer, P. J. (2005) · Neuron · doi:10.1016/j.neuron.2005.03.029 · Cited by 261

Human α6 AChR subtypes: subunit composition, assembly, and pharmacological responses

Kuryatov, A., Olale, F., Cooper, J., Choi, C. H., & Lindstrom, J. M. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(00)00144-1 · Cited by 224

Human Tobacco Smokers in Early Abstinence Have Higher Levels of β2* Nicotinic Acetylcholine Receptors than Nonsmokers

Staley, J. K., Krishnan-Sarin, S., Cosgrove, K. P., Krantzler, E., Frohlich, E., Perry, E., Dubin, J. A., Estok, K., Brenner, E., Baldwin, R. M., et al. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0546-06.2006 · Cited by 229

Human Bronchial Epithelial and Endothelial Cells Express α7 Nicotinic Acetylcholine Receptors

Wang, Y., Pereira, E. F. R., Maus, A. D. J., Ostlie, N. S., Navaneetham, D., Lei, S., Albuquerque, E. X., & Conti-Fine, B. M. (2001) · Molecular Pharmacology · doi:10.1124/mol.60.6.1201 · Cited by 218

Roles of Accessory Subunits in α4β2* Nicotinic Receptors

Kuryatov, A., Onksen, J., & Lindstrom, J. (2008) · Molecular Pharmacology · doi:10.1124/mol.108.046789 · Cited by 195

Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation

Resende, R., & Adhikari, A. (2009) · Cell Communication and Signaling · doi:10.1186/1478-811x-7-20 · Cited by 183

Assembly of α4β2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons

Nashmi, R., Dickinson, M. E., McKinney, S., Jareb, M., Labarca, C., Fraser, S. E., & Lester, H. A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-37-11554.2003 · Cited by 188

Nicotinic Acetylcholine Receptors of Muscles and Nerves

Lindstrom, J. M. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1254.007 · Cited by 176

Acetylcholine Receptor (AChR) α5 Subunit Variant Associated with Risk for Nicotine Dependence and Lung Cancer Reduces (α4β2)2α5 AChR Function

Kuryatov, A., Berrettini, W., & Lindstrom, J. (2011) · Molecular Pharmacology · doi:10.1124/mol.110.066357 · Cited by 171

SSR180711, a Novel Selective α7 Nicotinic Receptor Partial Agonist: (1) Binding and Functional Profile

Biton, B., Bergis, O. E., Galli, F., Alain, N., Lochead, A. W., Jegham, S., Godet, D., Lanneau, C., Santamaria, R., Chesney, F., et al. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301189 · Cited by 174

Nicotine Withdrawal

McLaughlin, I., Dani, J. A., & De Biasi, M. (2015) · Current Topics in Behavioral Neurosciences · doi:10.1007/978-3-319-13482-6_4 · Cited by 191

Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery

Lester, H. A., Xiao, C., Srinivasan, R., Son, C. D., Miwa, J., Pantoja, R., Banghart, M. R., Dougherty, D. A., Goate, A. M., & Wang, J. C. (2009) · The AAPS Journal · doi:10.1208/s12248-009-9090-7 · Cited by 163

Subtype-selective up-regulation by chronic nicotine of high-affinity nicotinic receptors in rat brain demonstrated by receptor autoradiography

Nguyen, H. N., Rasmussen, B. A., & Perry, D. C. (2003) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.056408 · Cited by 148

The Comparative Pharmacology and Up-Regulation of Rat Neuronal Nicotinic Receptor Subtype Binding Sites Stably Expressed in Transfected Mammalian Cells

Xiao, Y., & Kellar, K. J. (2004) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.066787 · Cited by 148

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse

Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148

Assembly and trafficking of nicotinic acetylcholine receptors (Review)

Millar, N. S., & Harkness, P. C. (2008) · Molecular Membrane Biology · doi:10.1080/09687680802035675 · Cited by 143

The α4β2α5 nicotinic cholinergic receptor in rat brain is resistant to up‐regulation by nicotine in vivo

Mao, D., Perry, D. C., Yasuda, R. P., Wolfe, B. B., & Kellar, K. J. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05011.x · Cited by 133

Nicotine induces human neutrophils to produce IL-8 through the generation of peroxynitrite and subsequent activation of NF-κB

Iho, S., Tanaka, Y., Takauji, R., Kobayashi, C., Muramatsu, I., Iwasaki, H., Nakamura, K., Sasaki, Y., Nakao, K., & Takahashi, T. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.1202626 · Cited by 128

Neurobiological Mechanisms of Nicotine Reward and Aversion

Wills, L. P., Ables, J. L., Braunscheidel, K. M., Caligiuri, S. P. B., Elayouby, K. S., Fillinger, C., Ishikawa, M., Moen, J. K., & Kenny, P. J. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000299 · Cited by 134

Biogenesis, trafficking and up-regulation of nicotinic ACh receptors

Colombo, S. F., Mazzo, F., Pistillo, F., & Gotti, C. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.06.023 · Cited by 121

Nicotine-Induced Upregulation of Native Neuronal Nicotinic Receptors Is Caused by Multiple Mechanisms

Govind, A. P., Walsh, H., & Green, W. N. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5438-11.2012 · Cited by 116

SSR591813, a Novel Selective and Partial α4β2 Nicotinic Receptor Agonist with Potential as an Aid to Smoking Cessation

Cohen, C., Bergis, O. E., Galli, F., Lochead, A. W., Jegham, S., Biton, B., Léonardon, J., Avenet, P., Sgard, F., Besnard, F., et al. (2003) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.049262 · Cited by 114

Nicotine regulates multiple synaptic proteins by inhibiting proteasomal activity

Rezvani, K., Teng, Y., Shim, D., & De Biasi, M. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3353-07.2007 · Cited by 113

Allosteric mechanisms in normal and pathological nicotinic acetylcholine receptors

Changeux, J., & Edelstein, S. J. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00221-x · Cited by 113

Up-Regulation of Brain Nicotinic Acetylcholine Receptors in the Rat during Long-Term Self-Administration of Nicotine: Disproportionate Increase of the α6 Subunit

Parker, S. L., Fu, Y., McAllen, K., Luo, J., McIntosh, J. M., Lindstrom, J. M., & Sharp, B. M. (2004) · Molecular Pharmacology · doi:10.1124/mol.65.3.611 · Cited by 105

Nicotinic acetylcholine receptors containing α7 subunits on rat cortical neurons do not undergo long‐lasting inactivation even when up‐regulated by chronic nicotine exposure

Kawai, H. D., & Berg, D. K. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00526.x · Cited by 102

Inside-out neuropharmacology of nicotinic drugs

Henderson, B. J., & Lester, H. A. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.01.022 · Cited by 109

Pharmacological chaperoning: A primer on mechanism and pharmacology

Leidenheimer, N. J., & Ryder, K. G. (2014) · Pharmacological Research · doi:10.1016/j.phrs.2014.01.005 · Cited by 107

Expression of Functional Human α6β2β3* Acetylcholine Receptors in Xenopus laevis Oocytes Achieved through Subunit Chimeras and Concatamers

Kuryatov, A., & Lindstrom, J. M. (2010) · Molecular Pharmacology · doi:10.1124/mol.110.066159 · Cited by 97

Megacystis-microcolon-intestinal hypoperistalsis syndrome and the absence of the α3 nicotinic acetylcholine receptor subunit

Richardson, C., Morgan, J. M., Jasani, B., Green, J. T., Rhodes, J., Williams, G. T., Lindstrom, J. M., Wonnacott, S., Thomas, G. A. O., & Smith, V. V. (2001) · Gastroenterology · doi:10.1053/gast.2001.26320 · Cited by 96

Single channel properties of human α3 AChRs: impact of β2, β4 and α5 subunits

Nelson, M. E., & Lindstrom, J. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.0657u.x · Cited by 92

Evidence for the involvement of TNF and NF-?B in hippocampal synaptic plasticity

Albensi, B. C., & Mattson, M. P. (2000) · Synapse · doi:10.1002/(sici)1098-2396(200002)35:2 · Cited by 527

The Structures of Neuronal Nicotinic Receptors

Lindstrom, J. M. (2000) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-57079-7_6 · Cited by 91

Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity

Luo, J., Taylor, P., Losen, M. H., Baets, M. H. D., Shelton, G. D., & Lindstrom, J. M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2833-09.2009 · Cited by 90

Regulation of neuronal nicotinic receptor traffic and expression

Gaimarri, A., Moretti, M., Riganti, L., Zanardi, A., Clementi, F., & Gotti, C. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.02.005 · Cited by 89

Nicotinic α5 subunit deletion locally reduces high‐affinity agonist activation without altering nicotinic receptor numbers

Brown, R. W. B., Collins, A. C., Lindstrom, J. M., & Whiteaker, P. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04700.x · Cited by 88

Up-regulation of Nicotinic Receptors by Nicotine Varies with Receptor Subtype

Walsh, H., Govind, A. P., Mastro, R., Hoda, J. C., Bertrand, D., Vallejo, Y., & Green, W. N. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m703432200 · Cited by 87

Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity?

Corringer, P.-J., Sallette, J., & Changeux, J.-P. (2006) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2005.12.012 · Cited by 86

Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications

Zhao, S., Di, Y., Fan, H., Xu, C., Li, H., Wang, Y., Wang, W., Li, C., & Wang, J. (2024) · Molecular Biomedicine · doi:10.1186/s43556-024-00230-x · Cited by 95

Receptor-mediated tobacco toxicity: acceleration of sequential expression of 5 and 7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke

Arredondo, J., Chernyavsky, A. I., Jolkovsky, D. L., Pinkerton, K. E., & Grando, S. A. (2007) · The FASEB Journal · doi:10.1096/fj.07-9965.com · Cited by 88

[3H]Nicotine binding in peripheral blood cells of smokers is correlated with the number of cigarettes smoked per day

Benhammou, K., Lee, M., Strook, M. L., Sullivan, B. F., Logel, J., Raschen, K., Gotti, C., & Leonard, S. S. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(00)00153-2 · Cited by 86

Spatiotemporal Patterns of Activity in an Intact Mammalian Network with Single-Cell Resolution: Optical Studies of Nicotinic Activity in an Enteric Plexus

Obaid, A. L., Koyano, T., Lindstrom, J. M., Sakai, T., & Salzberg, B. M. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-08-03073.1999 · Cited by 84

Binding and functional activity of nicotinic cholinergic receptors in selected rat brain regions are increased following long‐term but not short‐term nicotine treatment

Nguyen, H. N., Rasmussen, B. A., & Perry, D. C. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02482.x · Cited by 83

IgE-induced degranulation of mucosal mast cells is negatively regulated via nicotinic acetylcholine receptors

Kageyama‐Yahara, N., Suehiro, Y., Yamamoto, T., & Kadowaki, M. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.10.004 · Cited by 85

Subsets of acetylcholine-stimulated 86Rb+ efflux and [125I]-epibatidine binding sites in C57BL/6 mouse brain are differentially affected by chronic nicotine treatment

Marks, M. J., Rowell, P. P., Cao, J., Grady, S. R., McCallum, S. E., & Collins, A. C. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.02.009 · Cited by 81

Characterization of ganglionic acetylcholine receptor autoantibodies

Vernino, S. A., Lindstrom, J. M., Hopkins, S., Wang, Z., & Low, P. A. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.03.017 · Cited by 83

An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine

Sallette, J., Bohler, S., Benoit, P., Soudant, M., Pons, S., Le Novère, N., Changeux, J.-P., & Corringer, P. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m308260200 · Cited by 80

Nicotine-induced Attentional Enhancement in Rats Effects of Chronic Exposure to Nicotine

Hahn, B. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00348-2 · Cited by 78

Synergistic control of keratinocyte adhesion through muscarinic and nicotinic acetylcholine receptor subtypes

Nguyen, V. T., Chernyavsky, A. I., Arredondo, J., Bercovich, D., Orr‐Urtreger, A., Vetter, D. E., Wess, J., Beaudet, A. L., Kitajima, Y., & Grando, S. A. (2004) · Experimental Cell Research · doi:10.1016/j.yexcr.2003.12.010 · Cited by 78

Functional Properties of Human Nicotinic Achrs Expressed by Imr-32 Neuroblastoma Cells Resemble Those of α3β4 Achrs Expressed in Permanently Transfected Hek Cells

Nelson, M. E., Wang, F., Kuryatov, A., Choi, C. H., Gerzanich, V., & Lindstrom, J. M. (2001) · The Journal of General Physiology · doi:10.1085/jgp.118.5.563 · Cited by 77

Changes in Conformation and Subcellular Distribution of α4β2 Nicotinic Acetylcholine Receptors Revealed by Chronic Nicotine Treatment and Expression of Subunit Chimeras

Harkness, P. C., & Millar, N. S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-23-10172.2002 · Cited by 74

β3 Subunits Promote Expression and Nicotine-Induced Up-Regulation of Human Nicotinic α6* Nicotinic Acetylcholine Receptors Expressed in Transfected Cell Lines

Tumkosit, P., Kuryatov, A., Luo, J., & Lindstrom, J. (2006) · Molecular Pharmacology · doi:10.1124/mol.106.027326 · Cited by 73

Characterization of the recombinant human neuronal nicotinic acetylcholine receptors α3β2 and α4β2 stably expressed in HEK293 cells

Chavez-Noriega, L. E., Gillespie, A. J., Stauderman, K. A., Crona, J. H., Claeps, B. O., Elliott, K. J., Reid, R. T., Rao, T. S., Veliçelebi, G., Harpold, M. M., et al. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(00)00134-9 · Cited by 73

Deletion of the beta 2 nicotinic acetylcholine receptor subunit alters development of tolerance to nicotine and eliminates receptor upregulation

McCallum, S. E., Collins, A. C., Paylor, R. E., & Marks, M. J. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0076-6 · Cited by 71

Formation of functional α3β4α5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach

Groot‐Kormelink, P. J., Boorman, J. P., & Sivilotti, L. G. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704313 · Cited by 64

Regulation of the Neuronal Nicotinic Acetylcholine Receptor by Src Family Tyrosine Kinases

Wang, K., Hackett, J. T., Cox, M., van Hoek, M. L., Lindstrom, J. M., & Parsons, S. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309652200 · Cited by 64

Long-Lasting Enhancement of Glutamatergic Synaptic Transmission by Acetylcholine Contrasts with Response Adaptation after Exposure to Low-Level Nicotine

Girod, R., & Role, L. W. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05182.2001 · Cited by 62

Ubiquilin-1 Regulates Nicotine-induced Up-regulation of Neuronal Nicotinic Acetylcholine Receptors

Ficklin, M. B., Zhao, S., & Feng, G. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506781200 · Cited by 59

Chronic Nicotine Exposure Enhances Insulin-Induced Mitogenic Signaling via Up-Regulation of α7 Nicotinic Receptors in Isolated Rat Aortic Smooth Muscle Cells

Wada, T., Naito, M., Kenmochi, H., Tsuneki, H., & Sasaoka, T. (2006) · Endocrinology · doi:10.1210/en.2006-0907 · Cited by 58

Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes

David, R., Ciuraszkiewicz, A., Simeone, X., Orr‐Urtreger, A., Papke, R. L., McIntosh, J. M., Huck, S., & Scholze, P. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07133.x · Cited by 58

Agonist regulation of rat alpha 3 beta 4 nicotinic acetylcholine receptors stably expressed in human embryonic kidney 293 cells.

Meyer, E. L., Xiao, Y., & Kellar, K. J. (2001) · PubMed · Cited by 58

Differential effects of chronic drug treatment on α3* and α7 nicotinic receptor binding sites, in hippocampal neurones and SH‐SY5Y cells

Ridley, D. L., Rogers, A. T., & Wonnacott, S. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704207 · Cited by 58

Nicotinic acetylcholine receptors: upregulation, age‐related effects and associations with drug use

Melroy-Greif, W. E., Stitzel, J. A., & Ehringer, M. A. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12251 · Cited by 58

Nicotine-Modulated Subunit Stoichiometry Affects Stability and Trafficking of 3 4 Nicotinic Receptor

Mazzo, F., Pistillo, F., Grazioso, G., Clementi, F., Borgese, N., Gotti, C., & Colombo, S. F. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2393-13.2013 · Cited by 57

Role of acetylcholine receptors in proliferation and differentiation of P19 embryonal carcinoma cells.

Resende, R. R., Alves, A. S., Britto, L. R. G., & Ulrich, H. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.01.003 · Cited by 58

Prenatal Nicotine Exposure

Tizabi, Y., Russell, L. T., Nespor, S. M., Perry, D. C., & Grunberg, N. E. (2000) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(00)00171-4 · Cited by 55

Acute Activation, Desensitization and Smoldering Activation of Human Acetylcholine Receptors

Campling, B. G., Kuryatov, A., & Lindstrom, J. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079653 · Cited by 55

Chronic neonatal nicotine upregulates heteromeric nicotinic acetylcholine receptor binding without change in subunit mRNA expression

Huang, L. Z., & Winzer‐Serhan, U. H. (2006) · Brain Research · doi:10.1016/j.brainres.2006.06.084 · Cited by 52

Nicotinic Receptor Subtypes in Rat Hippocampal Slices Are Differentially Sensitive to Desensitization and Early in Vivo Functional Up-Regulation by Nicotine and to Block by Bupropion

Alkondon, M., & Albuquerque, E. X. (2005) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.081232 · Cited by 51

Nicotine and Behavioral Sensitization

Mao, D., & McGehee, D. S. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-009-9230-7 · Cited by 50

The Ubiquitin–Proteasome System Regulates the Stability of Neuronal Nicotinic Acetylcholine Receptors

Rezvani, K. S., Teng, Y., & Biasi, M. D. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-009-9272-x · Cited by 48

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