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Oxidative stress-induced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria

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Mitochondrial DNA mutations in RRF of healthy subjects of different age

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Neuromelanin MRI in a family with mitochondrial parkinsonism harboring a Y955C mutation in POLG1

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Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia†

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A mechanistic view of human mitochondrial DNA polymerase γ: Providing insight into drug toxicity and mitochondrial disease

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Human Mitochondrial RNA Polymerase: Evaluation of the Single-Nucleotide-Addition Cycle on Synthetic RNA/DNA Scaffolds

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Inherited Mitochondrial DNA Depletion

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MMS Exposure Promotes Increased MtDNA Mutagenesis in the Presence of Replication-Defective Disease-Associated DNA Polymerase γ Variants

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MITOL-dependent ubiquitylation negatively regulates the entry of PolγA into mitochondria

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Progressive external ophthalmoplegia: A new family with tremor and peripheral neuropathy

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The use of lymphocytes to screen for oxidative phosphorylation disorders

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Structural basis for DNA proofreading

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Purification and functional characterization of human mitochondrial DNA polymerase gamma harboring disease mutations

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POLG mutation in a patient with cataracts, early-onset distal muscle weakness and atrophy, ovarian dysgenesis and 3-methylglutaconic aciduria

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Structural and Molecular Basis for Mitochondrial DNA Replication and Transcription in Health and Antiviral Drug Toxicity

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Overexpression of DNA Polymerase Zeta Reduces the Mitochondrial Mutability Caused by Pathological Mutations in DNA Polymerase Gamma in Yeast

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A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma

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Characterization of a Natural Mutator Variant of Human DNA Polymerase λ which Promotes Chromosomal Instability by Compromising NHEJ

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Distinct Function of Conserved Amino Acids in the Fingers of Saccharomyces cerevisiae DNA Polymerase α

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Construction and validation of a yeast model system for studying in vivo the susceptibility to nucleoside analogues of DNA polymerase gamma allelic variants

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The Exonuclease Activity of the Yeast Mitochondrial DNA Polymerase γ Suppresses Mitochondrial DNA Deletions Between Short Direct Repeats in Saccharomyces cerevisiae

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Biginelli Multicomponent Reactions in Polymer Science

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Chapter 30 Mitochondrial disorders

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Mutations in human DNA polymerase confer unique mechanisms of catalytic deficiency that mirror the disease severity in mitochondrial disorder patients

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C-Terminal Extension of the Yeast Mitochondrial DNA Polymerase Determines the Balance between Synthesis and Degradation

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Fidelity and Processivity of Reverse Transcription by the Human Mitochondrial DNA Polymerase

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Low Variability of the POLG (CAG) n Repeat in North Eurasian Populations

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The Gly-952 Residue of Saccharomyces cerevisiae DNA Polymerase α Is Important in Discriminating Correct Deoxyribonucleotides from Incorrect Ones

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Transgenic mouse models of mitochondrial toxicity associated with HIV/AIDS and antiretrovirals

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Modelling POLG mutations in mice unravels a critical role of POLγΒ in regulating phenotypic severity

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Networked Communication between Polymerase and Exonuclease Active Sites in Human Mitochondrial DNA Polymerase

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Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders.

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Review Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders �

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Effect of the Y955C Mutation on Mitochondrial DNA Polymerase Nucleotide Incorporation Efficiency and Fidelity

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Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia

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Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia†

Atanassova, N., Fusté, J. M., Wanrooij, S., Macao, B., Goffart, S., Bäckström, S., Farge, G., Khvorostov, I., Larsson, N., Spelbrink, J. N., et al. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddq565 · Cited by 30 · see citing works