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Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis

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Phosphorylation of Serine 18 Regulates Distinct p53 Functions in Mice

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Functional Interaction of H2AX, NBS1, and p53 in ATM-Dependent DNA Damage Responses and Tumor Suppression

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New insights into p53 activation

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Regulation of Protein Citrullination through p53/PADI4 Network in DNA Damage Response

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Increased Sensitivity to UV Radiation in Mice with a p53 Point Mutation at Ser389

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Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage

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Puma is required for p53-induced depletion of adult stem cells

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Evidence for the Direct Binding of Phosphorylated p53 to Sites of DNA Breaks In vivo

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ATM Phosphorylation of Mdm2 Ser394 Regulates the Amplitude and Duration of the DNA Damage Response in Mice

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Converging Mechanisms of p53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy

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p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis

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A New Twist in the Feedback Loop: Stress-Activated MDM2 Destabilization is Required for p53 Activation

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Oncogene activation in melanocytes links reactive oxygen to multinucleated phenotype and senescence

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The p53‐inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation

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Molecular cloning, characterization and expression analysis of tumor suppressor protein p53 from orange-spotted grouper, Epinephelus coioides in response to temperature stress

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Functions of p53 in pluripotent stem cells

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Mutant TP53 Posttranslational Modifications: Challenges and Opportunities

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Differentiation-Induced Radioresistance in Muscle Cells

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Porphyrin Homeostasis Maintained by ABCG2 Regulates Self-Renewal of Embryonic Stem Cells

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The Ataxia Telangiectasia–Mutated Target Site Ser18 Is Required for p53-Mediated Tumor Suppression

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C/EBPα Is a DNA Damage-Inducible p53-Regulated Mediator of the G 1 Checkpoint in Keratinocytes

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Mouse Mutants Reveal that Putative Protein Interaction Sites in the p53 Proline-Rich Domain Are Dispensable for Tumor Suppression

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Induction of genetic instability by gain-of-function p53 cancer mutants

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Multivalent Binding of p53 to the STAGA Complex Mediates Coactivator Recruitment after UV Damage

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Dissecting functional roles of p53 N‐terminal transactivation domains by microarray expression analysis

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Regulation of p53 by the 14-3-3 protein interaction network: new opportunities for drug discovery in cancer

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Illuminating p53 function in cancer with genetically engineered mouse models

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Regulation of Kruppel-like Factor 6 Tumor Suppressor Activity by Acetylation

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Tumorigenic and Immunogenic Properties of Induced Pluripotent Stem Cells: a Promising Cancer Vaccine

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Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53

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Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants

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The Xeroderma Pigmentosum Group E Gene Product DDB2 Activates Nucleotide Excision Repair by Regulating the Level of p21Waf1/Cip1

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p53 Basic C Terminus Regulates p53 Functions through DNA Binding Modulation of Subset of Target Genes

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Mechanistic Studies of MDM2-mediated Ubiquitination in p53 Regulation

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High Mobility Group Protein B1 Is an Activator of Apoptotic Response to Antimetabolite Drugs

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Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

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Switching on p53: an essential role for protein phosphorylation?

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Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo

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Correction: Phosphorylation of Daxx by ATM Contributes to DNA Damage-Induced p53 Activation

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The p53-Mdm2 Loop: A Critical Juncture of Stress Response

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Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis

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Lack of p53 Ser389 Phosphorylation Predisposes Mice to Develop 2-Acetylaminofluorene–Induced Bladder Tumors but not Ionizing Radiation–Induced Lymphomas

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The roles of MDM2 and MDMX phosphorylation in stress signaling to p53

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Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53–induced apoptosis

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Activation of cAMP Signaling Interferes with Stress-Induced p53 Accumulation in ALL-Derived Cells by Promoting the Interaction between p53 and HDM2

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Context‐Dependent Enhancement of Induced Pluripotent Stem Cell Reprogramming by Silencing Puma

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Nucleotide excision repair- and p53-deficient mouse models in cancer research

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Differential Recognition of Phosphorylated Transactivation Domains of p53 by Different p300 Domains

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Controlling the Mdm2-Mdmx-p53 Circuit

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RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses

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Applications of the human p53 knock‐in ( Hupki ) mouse model for human carcinogen testing

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Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.

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Inhibitory effect of polyphenol cyanidin on TNF-α-induced apoptosis through multiple signaling pathways in endothelial cells

Xu, J., Ikeda, K., & Yamori, Y. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.09.006 · Cited by 28

Teratogen-Induced Activation of p53 in Early Postimplantation Mouse Embryos

Hosako, H., Little, S. A., Barrier, M., & Mirkes, P. E. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl143 · Cited by 28

Damaged DNA Binding Protein 2 in Reactive Oxygen Species (ROS) Regulation and Premature Senescence

Roy, N., Bagchi, S., & Raychaudhuri, P. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms130911012 · Cited by 33

Using Mouse Models to Explore MDM-p53 Signaling in Development, Cell Growth, and Tumorigenesis

Gannon, H., & Jones, S. N. (2012) · Genes & Cancer · doi:10.1177/1947601912455324 · Cited by 25

A genotoxicity test system based on p53R2 gene expression in human cells: Assessment of its reactivity to various classes of genotoxic chemicals

Ohno, K., Ishihata, K., Tanaka-Azuma, Y., & Yamada, T. (2008) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2008.07.002 · Cited by 24

Oxygenomics in environmental stress

Sone, H., Akanuma, H., & Fukuda, T. (2010) · Redox Report · doi:10.1179/174329210x12650506623843 · Cited by 22

Insights into Selective Activation of p53 DNA Binding by c-Abl

Wei, G., Li, A. G., & Liu, X. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m409522200 · Cited by 22

The phenotype of MDM2 auto-degradation after DNA damage is due to epitope masking by phosphorylation

Cheng, Q., & Chen, J. (2011) · Cell Cycle · doi:10.4161/cc.10.7.15249 · Cited by 21

Regulation of p53-dependent transcription

Jõers, A. (2004) · DSpace repository (University of Tartu) · Cited by 20

Reactive Oxygen Species-Mediated p53 Core-Domain Modifications Determine Apoptotic or Necrotic Death in Cancer Cells

Gogna, R., Madan, E., Kuppusamy, P., & Pati, U. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4103 · Cited by 20

Simulating Molecular Mechanisms of the MDM2-Mediated Regulatory Interactions: A Conformational Selection Model of the MDM2 Lid Dynamics

Verkhivker, G. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040897 · Cited by 18

Functional role of p53 N-terminal phosphorylation in regulating the p53 response to DNA damage

Chao, C. (2006) · eScholarship (California Digital Library)

Phosphorylation of murine p53 at Ser-18 regulates the p53 responses to DNA damage

Chao, C., Saito, S., Anderson, C. W., Appella, E., & Xu, Y. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.220252297 · Cited by 168

Phosphorylation of Serine 18 Regulates Distinct p53 Functions in Mice

Sluss, H. K., Armata, H., Gallant, J., & Jones, S. N. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.3.976-984.2004 · Cited by 152

Ser18 and 23 phosphorylation is required for p53‐dependent apoptosis and tumor suppression

Chao, C., Herr, D., Chun, J., & Xu, Y. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601167 · Cited by 158

Regulation of p53 antiproliferative function by transactivation domain phosphorylation at threonine 18 and serine 20

Jabbur, J. R. (2001) · Digital Commons-TMC (Texas Medical Center)