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Mammalian Zinc Transport, Trafficking, and Signals
Open accessAbstract
Structural, catalytic, and regulatory functions of zinc in biology continue to be defined. The number of genes coding for proteins with zinc-binding domains is conservatively estimated at >3% of the human genome but possibly is as much as 10% (1, 2). Zinc utilization in abundant, yet diverse, applications illustrates why organisms have evolved specific pathways to homeostatically regulate availability of this essential micronutrient at specific cellular sites through an array of transporters. Animals regulate zinc gain and loss efficiently.
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Metadata
- Authors
- Cousins, R. J., Liuzzi, J. P., & Lichten, L. A.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2006-08
- Volume
- 281
- Issue
- 34
- Pages
- 24085-24089
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2157810907
- Cited by
- 705
- References
- 3
- FWCI
- 28.12
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
