Enteral feeding: The effect on faecal output, the faecal microflora and SCFA concentrations
Open accessAbstract
Enteral tube feeding is common in both the hospital and community environment; however, patients can suffer alterations in faecal output that can have serious clinical sequelae. Problems associated with accurate characterisation of faecal output and definition of diarrhoea impede the comparison of research studies and prevent standardised assessment of therapeutic interventions in clinical practice. The colonic microflora may protect the patient against diarrhoea by preventing enteropathogenic infection and by producing SCFA that stimulate colonic water absorption. However, studies in healthy volunteers suggest that the composition of the enteral formula may have a negative impact on the microflora and SCFA concentrations. The addition of fructo-oligosaccharides to the enteral formula may partially prevent negative alterations to the microflora, although conclusive data from studies in patients are not yet available. Modification of the microflora with probiotics and prebiotics may hold potential in prophylaxis against diarrhoea during enteral tube feeding.
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The low content or even absence of fiber and resistant starch in feeding regimens limits energy substrate availability for gut microbes, and abnormal fluid secretion into the colon triggered by enteral formula infusion confers deleterious effects on the gut microbiota.
“The low content (or even absence) of fiber and resistant starch in these feeding regimens limits energy substrate availability for the gut microbes; abnormal fluid secretion into the colon triggered by enteral formula infusion also confers deleterious effects on the gut microbiota [84,85].”
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Flagged first, then by citations
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Sorted by citations
Short-chain fatty acids: ready for prime time?
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“The low content (or even absence) of fiber and resistant starch in these feeding regimens limits energy substrate availability for the gut microbes; abnormal fluid secretion into the colon triggered by enteral formula infusion also confers deleterious effects on the gut microbiota [84,85].”
Background
- Authors
- Whelan, K., Judd, P. A., Preedy, V. R., & Taylor, M. A.
- Affiliations
- King's College London (GB)
- University of Lancashire (GB)
- University of Nottingham (GB)
- Corresponding author
- Whelan, Kevin
- Venue
- Proceedings of The Nutrition Society
- Publisher
- Cambridge University Press (CUP)
- Published
- 2004-02
- Volume
- 63
- Issue
- 1
- Pages
- 105-113
- ISSN
- 0029-6651 (ISSN-L)
- 1475-2719
- OpenAlex
- W2158409296
- Cited by
- 65
- References
- 74
- Citations by year
- 2026: 3 · 2025: 2 · 2022: 1 · 2021: 4 · 2020: 1 · 2019: 6 · 2018: 2 · 2017: 3 · 2016: 5 · 2015: 5 · 2014: 3 · 2013: 2 · 2012: 1
- FWCI
- 0.52
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of The Nutrition Society (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- King's College London
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- enteral nutrition, fecal output, diarrhea, colonic microbiota, short-chain fatty acids, fructooligosaccharides, probiotics, prebiotics, diarrhea prevention, colonic water absorption
- MeSH terms
- Colon, Diarrhea, Enteral Nutrition, Fatty Acids, Volatile, Feces, Fermentation, Humans, Probiotics
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