Changes in oxytocin and cortisol in active-alert hypnosis: hormonal changes benefiting low hypnotizable participants
Abstract
It is increasingly clear that oxytocin and cortisol play an intricate role in the regulation of behavior and emotions impacting health, relationships, and well-being. Their long-term, cross-generational effect makes them an important focus of the present study. This exploratory research examined changes in oxytocin and cortisol levels and their correlations with different phenomenological measures in both hypnotist and subject during active-alert hypnosis. The level of oxytocin increased whereas the level of cortisol decreased in the hypnotist. When comparing the oxytocin changes of subjects with their hypnotizability, those with low hypnotizability scores experienced an increase in oxytocin, and those with medium and high hypnotizability scores showed no change or decrease. This could explain why clients' hypnotizability is not considered an important factor during hypnotherapy.
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Emerging psychophysiological studies report alterations in cortisol and oxytocin dynamics during hypnotic interaction.
“Emerging psychophysiological studies report alterations in cortisol and oxytocin dynamics during hypnotic interaction (19, 34).”
From Mindfulness and clinical hypnotherapy in sexual desire disorders: mechanisms, psychophysiological pathways, and integrative therapeutic sequencing (2026) · cites this paper as [34]
Emerging psychophysiological findings reporting modulation of cortisol and oxytocin dynamics during hypnotic interaction offer additional biological plausibility.
“Emerging psychophysiological findings reporting modulation of cortisol and oxytocin dynamics during hypnotic interaction (19, 34) offer additional biological plausibility.”
From Mindfulness and clinical hypnotherapy in sexual desire disorders: mechanisms, psychophysiological pathways, and integrative therapeutic sequencing (2026) · cites this paper as [34]
Evidence from adjacent medical domains supports mechanistic plausibility regarding stress regulation and attentional modulation.
“Evidence from adjacent medical domains supports mechanistic plausibility regarding stress regulation and attentional modulation (15, 19, 27, 34, 36, 37).”
From Mindfulness and clinical hypnotherapy in sexual desire disorders: mechanisms, psychophysiological pathways, and integrative therapeutic sequencing (2026) · cites this paper as [34]
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- Authors
- Kasos, E., Kasos, K., Pusztai, F., Polyák, Á., Kovács, K. J., & Varga, K.
- Affiliations
- Doctoral School of Psychology, Eötvös Loránd University, Budapest, Hungary
- Eötvös Loránd University (HU)
- HUN-REN Institute of Experimental Medicine (HU)
- Venue
- International Journal of Clinical and Experimental Hypnosis
- Publisher
- Informa UK Limited
- Published
- 2018-08-28
- Volume
- 66
- Issue
- 4
- Pages
- 404-427
- ISSN
- 0020-7144 (ISSN-L)
- 1744-5183
- OpenAlex
- W2889257024
- Cited by
- 20
- References
- 70
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2023: 4 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 3 · 2018: 1
- FWCI
- 1.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Clinical and Experimental Hypnosis (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Hungarian Scientific Research Fund (OTKA K100845)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- oxytocin, cortisol, hypnotic susceptibility, hypnotists, hypnotherapy, hormonal changes
- MeSH terms
- Female, Humans, Hydrocortisone, Hypnosis, Oxytocin, Psychological Tests, Surveys and Questionnaires, Saliva, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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