Hypoxia: a Double-Edged Sword in Cancer Therapy

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2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF

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Detection and Characterization of Tumor Hypoxia Using pO ₂ Histography

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Hypoxia and hypoxia-inducible factors: master regulators of metastasis

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1α-degradative pathway

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Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression

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Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways

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A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85

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Role of hypoxia in the hallmarks of human cancer

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Untitled work

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Hypoxia-driven selection of the metastatic phenotype

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Tumor hypoxia: A target for selective cancer therapy

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Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies

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Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells.

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Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents

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Negative and positive regulation of HIF-1: A complex network

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Development of a hypoxia-responsive vector for tumor-specific gene therapy

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Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs

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Targeting hypoxia cell signaling for cancer therapy

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Hypoxia‐inducible factor‐1α contributes to hypoxia‐induced chemoresistance in gastric cancer

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Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302

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Hypoxia-selective antitumor agents. 7. Metal complexes of aliphatic mustards as a new class of hypoxia-selective cytotoxins. Synthesis and evaluation of cobalt(III) complexes of bidentate mustards

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Clostridia in cancer therapy

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Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer

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Hypoxia Induces Escape from Innate Immunity in Cancer Cells via Increased Expression of ADAM10: Role of Nitric Oxide

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Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels

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HIF-1 and tumour radiosensitivity

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Phase II study of the safety and antitumor activity of the hypoxia-activated prodrug TH-302 in combination with doxorubicin in patients with advanced soft tissue sarcoma

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Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of TH-302, a Hypoxia-Activated Prodrug, in Patients with Advanced Solid Malignancies

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Cannabidiol and Oxygen-Ozone Combination Induce Cytotoxicity in Human Pancreatic Ductal Adenocarcinoma Cell Lines

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Upregulation of lncRNA AGAP2‑AS1 is an independent predictor of poor survival in patients with clear cell renal carcinoma

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Novel Carbon Ion and Proton Partial Irradiation of Recurrent Unresectable Bulky Tumors (Particle-PATHY): Early Indication of Effectiveness and Safety

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Hypoxia-Induced Upregulation of lncRNA ELFN1-AS1 Promotes Colon Cancer Growth and Metastasis Through Targeting TRIM14 via Sponging miR-191-5p

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Influence of Body Mass Index on the Clinicopathologic Features of Papillary Thyroid Carcinoma

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Novel Quinoxaline-2-Carbonitrile-1,4-Dioxide Derivatives Suppress HIF1α Activity and Circumvent MDR in Cancer Cells

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Hypoxia Is Associated with Increased Immune Infiltrates and Both Anti-Tumour and Immune Suppressive Signalling in Muscle-Invasive Bladder Cancer

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Glaucocalyxin a prevents hypoxia-induced epithelial-mesenchymal transition in human gastric cancer cells through the PI3K/Akt signaling pathway

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Balanophorin B inhibited glycolysis with the involvement of HIF-1α

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LINCS gene expression signature analysis revealed bosutinib as a radiosensitizer of breast cancer cells by targeting eIF4G1

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Impact of Hypoxia on Relative Biological Effectiveness and Oxygen Enhancement Ratio for a 62-MeV Therapeutic Proton Beam

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Prognostic value of the cervical lymph node necrosis ratio in nasopharyngeal carcinoma

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Prognostic role of diffusion weighted and dynamic contrast-enhanced MRI in loco-regionally advanced head and neck cancer treated with concomitant chemoradiotherapy

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Hypoxia-Induced Photogenic Radicals by Eosin Y for Efficient Phototherapy of Hypoxic Tumors

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A dynamic nomogram combining tumor stage and magnetic resonance imaging features to predict the response to induction chemotherapy in locally advanced nasopharyngeal carcinoma

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Hypoxia-induced NAD+ interventions promote tumor survival and metastasis by regulating mitochondrial dynamics

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Regulatory role of the transforming growth factor-β signaling pathway in the drug resistance of gastrointestinal cancers

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Hypoxia-inducible lipid droplet-associated (HILPDA) facilitates the malignant phenotype of lung adenocarcinoma cells in vitro through modulating cell cycle pathways

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Revision of the Regioselectivity of the Beirut Reaction of Monosubstituted Benzofuroxans with Benzoylacetonitrile. 6-Substituted quinoxaline-2-carbonitrile 1,4- dioxides: Structural Characterization and Estimation of Anticancer Activity and Hypoxia Selectivity

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Hypoxia stimulates the migration and invasion of osteosarcoma via up-regulating the NUSAP1 expression

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Analysis of anemia and iron supplementation among glioblastoma patients reveals sex-biased association between anemia and survival

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Target for tumor hypoxia

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Tumor Hypoxia and Radioresistance

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A Review of the Role of Hypoxia in Radioresistance in Cancer Therapy

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An Enhanced Scrutiny of Mechanistic and Translational Approaches to Extinguish Cancer Hypoxia

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Tumor Hypoxia

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