Depression in multiple sclerosis

Patten, Scott B.; Marrie, Ruth Ann; Carta, Mauro G.

doi:10.1080/09540261.2017.1322555

Cited by 262Multiple Sclerosis Research StudiesTreatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Depression in multiple sclerosis

Patten, Scott B., Marrie, Ruth Ann, Carta, Mauro G.·2017·International Review of Psychiatry

DOI 10.1080/09540261.2017.1322555

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Abstract

Depressive disorders occur in up to 50% of people living with multiple sclerosis (MS). Prevalence estimates are generally 2-3-times higher than those of the general population. Myriad aetiologic factors may contribute to the aetiology of depression in MS including biological mechanisms (e.g. hippocampal microglial activation, lesion burden, regional atrophy), as well as the stressors, threats, and losses that accompany living with an unpredictable and often disabling disease. Some prominent risk factors for depression such as (younger) age, (female) sex, and family history of depression are less consistently associated with depression in MS than they are in the general population. Management of depression in MS has not been well studied, but available data on detection and treatment align with general principles of depression management. While the validity of standard measurement scales has often been questioned, available evidence suggests that standard scales provide valid ratings. Evidence for the effectiveness of depression treatments in MS is limited, but available evidence supports the effectiveness of standard treatment approaches, including both cognitive behavioural therapies and antidepressant medications.

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From Distinct characteristics of hippocampal pathogenic th17 cells in a mouse model of depression (2018) · cites this paper as Patten et al., 2017

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Clinical correlates of CES-D depressive symptom ratings in an MS population
Patten, S. B., Lavorato, D. H., & Metz, L. M. (2005) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2005.06.010 · Cited by 43 · see citing works
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Adverse health behaviours are associated with depression and anxiety in multiple sclerosis: A prospective multisite study
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Prophylactic Antidepressant Treatment of Interferon-Induced Depression in Chronic Hepatitis C
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Duloxetine Is Effective in Treating Depression in Multiple Sclerosis Patients
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Point prevalence and correlates of depression in a national community sample with multiple sclerosis
Viner, R., Fiest, K. M., Bulloch, A. G. M., Williams, J. V. A., Lavorato, D. H., Berzins, S. A., Jetté, N., Metz, L. M., & Patten, S. B. (2014) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2013.12.011 · Cited by 36 · see citing works
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Impact of a switch to fingolimod on depressive symptoms in patients with relapsing multiple sclerosis: An analysis from the EPOC (Evaluate Patient OutComes) trial
Hunter, S. F., Agius, M. A., Miller, D. M., Cutter, G., Barbato, L., McCague, K., Meng, X., Agashivala, N., Chin, P., & Hollander, E. (2016) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2016.03.024 · Cited by 34 · see citing works
Interferon beta treatment of multiple sclerosis
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Challenges in screening for depression in multiple sclerosis
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Depression and hypomania symptoms are associated with high dose corticosteroids treatment for MS relapses
Morrow, S. A., Barr, J., Rosehart, H., & Ulch, S. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.08.040 · Cited by 24 · see citing works
Combination treatment of fingolimod with antidepressants in relapsing–remitting multiple sclerosis patients with depression: a multicentre, open-label study – REGAIN
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Assessment of Depression in Multiple Sclerosis
Crawford, P., & Webster, N. J. (2009) · International Journal of MS Care · doi:10.7224/1537-2073-11.4.167 · Cited by 13 · see citing works
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Organic mood disorder: a valid psychiatry consultation diagnosis?
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Hippocampal Neuroinflammation and Depression: Relevance to Multiple Sclerosis and Other Neuropsychiatric Illnesses
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Patients with multiple sclerosis do not necessarily consume more alcohol or tobacco than the general population
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The Bidirectional Relationship of Depression and Inflammation: Double Trouble
Beurel, E., Toups, M., & Nemeroff, C. B. (2020) · Neuron · doi:10.1016/j.neuron.2020.06.002 · Cited by 2,136 · see citing works
Major depressive disorder
Marx, W., Penninx, B. W. J. H., Solmi, M., Furukawa, T. A., Firth, J., Carvalho, A. F., & Berk, M. (2023) · Nature Reviews Disease Primers · doi:10.1038/s41572-023-00454-1 · Cited by 850 · see citing works
Pragmatism as a paradigm for patient‐oriented research
Allemang, B. A., Sitter, K. C., & Dimitropoulos, G. (2021) · Health Expectations · doi:10.1111/hex.13384 · Cited by 243 · see citing works
Using the SF-36 measure to compare the health impact of multiple sclerosis and Parkinson's disease with normal population health profiles
Riazi, A. (2003) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.74.6.710 · Cited by 135 · see citing works
New Insights into the Pivotal Role of the Amygdala in Inflammation-Related Depression and Anxiety Disorder
Hu, P., Lü, Y., Pan, B., & Zhang, W. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911076 · Cited by 134 · see citing works
Effects of long-term administration of Multi-Strain Probiotic on circulating levels of BDNF, NGF, IL-6 and mental health in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled trial
Rahimlou, M., Hosseini, S. A., Majdinasab, N., Haghighizadeh, M. H., & Husain, D. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2020.1758887 · Cited by 108 · see citing works
Longitudinal course of depression symptoms in multiple sclerosis
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Smouldering‐Associated Worsening in Multiple Sclerosis: An International Consensus Statement on Definition, Biology, Clinical Implications, and Future Directions
Scalfari, A., Traboulsee, A. L., Oh, J., Airas, L. M., Bittner, S., Calabrese, M., García‐Domínguez, J. M., Granziera, C., Greenberg, B. M., Hellwig, K., et al. (2024) · Annals of Neurology · doi:10.1002/ana.27034 · Cited by 99 · see citing works
Anxiety and depression in patients with multiple sclerosis: The mediating effects of perceived social support
Henry, A., Tourbah, A., Camus, G., Deschamps, R., Mailhan, L., Castex, C., Gout, O., & Montreuil, M. (2019) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2018.09.039 · Cited by 95 · see citing works
The Psychological Impact of COVID-19 Pandemic on People With Multiple Sclerosis
Motolese, F., Rossi, M., Albergo, G., Stelitano, D., Villanova, M., di Lazzaro, V., & Capone, F. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.580507 · Cited by 83 · see citing works
The association of fatigue, pain, depression and anxiety with work and activity impairment in immune mediated inflammatory diseases
Enns, M. W., Bernstein, C. N., Kroeker, K., Graff, L. A., Walker, J. R., Lix, L. M., Hitchon, C. A., El-Gabalawy, R. M., Fisk, J. D., Marrie, R. A., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0198975 · Cited by 89 · see citing works
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miR-155 as an Important Regulator of Multiple Sclerosis Pathogenesis. A Review
Maciak, K., Dziedzic, A., Miller, E. D., & Saluk, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094332 · Cited by 87 · see citing works
Inflammation-Associated Synaptic Alterations as Shared Threads in Depression and Multiple Sclerosis
Bruno, A., Dolcetti, E., Rizzo, F. R., Fresegna, D., Musella, A., Gentile, A., Vito, F. D., Caioli, S., Guadalupi, L., Bullitta, S., et al. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00169 · Cited by 82 · see citing works
Psychometric properties of the PHQ-9 depression scale in people with multiple sclerosis: A systematic review
Patrick, S., & Connick, P. (2019) · PLoS ONE · doi:10.1371/journal.pone.0197943 · Cited by 67 · see citing works
Distinct characteristics of hippocampal pathogenic th17 cells in a mouse model of depression
Beurel, E., Lowell, J. A., & Jope, R. S. (2018) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.04.012 · Cited by 65 · see citing works
Depression in multiple sclerosis: Is one approach for its management enough?
Jones, C. D., Motl, R. W., & Sandroff, B. M. (2021) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2021.102904 · Cited by 63 · see citing works
Targeting the Adaptive Immune System in Depression: Focus on T Helper 17 Cells
Beurel, E., Medina-Rodriguez, E. M., & Jope, R. S. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000256 · Cited by 60 · see citing works
The Contribution of Gut Barrier Changes to Multiple Sclerosis Pathophysiology
Buscarinu, M. C., Fornasiero, A., Romano, S., Ferraldeschi, M., Mechelli, R., Reniè, R., Morena, E., Romano, C., Pellicciari, G., Landi, A. C., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01916 · Cited by 62 · see citing works
Infections in patients with multiple sclerosis: A national cohort study in Sweden
Castelo‐Branco, A., Chiesa, F., Conte, S., Bengtsson, C., Lee, S., Minton, N., Niemcryk, S. J., Lindholm, A., Rosenlund, M., Piehl, F., et al. (2020) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2020.102420 · Cited by 60 · see citing works
Chronic fatigue and depression due to multiple sclerosis: Immune-inflammatory pathways, tryptophan catabolites and the gut-brain axis as possible shared pathways
Ormstad, H., Simonsen, C. S., Broch, L., Maes, M. H. J., Anderson, G., & Celius, E. G. (2020) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2020.102533 · Cited by 55 · see citing works
Recommendations on Social Determinants of Health in Neurologic Disease
Towfighi, A., Berger, R. P., Corley, A. M. S., Glymour, M. M., Manly, J. J., & Skolarus, L. E. (2023) · Neurology · doi:10.1212/wnl.0000000000207562 · Cited by 55 · see citing works
The role of melatonin in Multiple Sclerosis
Skarlis, C., & Anagnostouli, M. C. (2019) · Neurological Sciences · doi:10.1007/s10072-019-04137-2 · Cited by 55 · see citing works
Modulation of neuroimmune cytokine networks by antidepressants: implications in mood regulation
Nava, R. G., Adri, A. S., Filgueiras, I. S., Nóbile, A. L., Barcelos, P. M., Corrêa, Y. L. G., de Oliveira, S. F., Cabral‐Miranda, G., Dias, H. D., Schimke, L. F., et al. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03532-y · Cited by 51 · see citing works
Identifying risk factors for cognitive issues in multiple sclerosis
Amato, M. P., Prestipino, E., & Bellinvia, A. (2019) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2019.1590199 · Cited by 40 · see citing works
MicroRNAs, Multiple Sclerosis, and Depression
Wang, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157802 · Cited by 45 · see citing works
Insights into the Pathophysiology of Psychiatric Symptoms in Central Nervous System Disorders: Implications for Early and Differential Diagnosis
Menculini, G., Chipi, E., Paoletti, F. P., Gaetani, L., Nigro, P., Simoni, S., Mancini, A., Tambasco, N., Filippo, M. D., Tortorella, A. A. V., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094440 · Cited by 42 · see citing works
Depression and anxiety in multiple sclerosis. Review of a fatal combination
Jellinger, K. A. (2024) · Journal of Neural Transmission · doi:10.1007/s00702-024-02792-0 · Cited by 41 · see citing works
Perinatal Depression and Anxiety in Women With Multiple Sclerosis: A Population-Based Cohort Study
Eid, K., Torkildsen, Ø. F., Aarseth, J., Flemmen, H. Ø., Holmøy, T., Lorentzen, Å. R., Myhr, K.-M., Riise, T., Simonsen, C., Torkildsen, C. F., et al. (2021) · Neurology · doi:10.1212/wnl.0000000000012062 · Cited by 35 · see citing works
Depressive symptoms in people with disabilities; secondary analysis of cross-sectional data from the United Kingdom and Greece.
Rotarou, E., & Sakellariou, D. (2017) · Disability and Health Journal · doi:10.1016/j.dhjo.2017.12.001 · Cited by 30 · see citing works
Mindfulness- and Acceptance-Based Interventions for Symptom Reduction in Individuals With Multiple Sclerosis: A Systematic Review and Meta-Analysis.
Han, A. (2021) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2021.03.011 · Cited by 29 · see citing works
Mental health and chronic diseases: a challenge to be faced from a new perspective
Carta, M. G., Patten, S. B., Nardi, A. E., & Bhugra, D. (2017) · International Review of Psychiatry · doi:10.1080/09540261.2017.1364885 · Cited by 28 · see citing works
Self-citation
Management of multiple sclerosis in older adults: review of current evidence and future perspectives
DiMauro, K. A., Swetlik, C., & Cohen, J. A. (2024) · Journal of Neurology · doi:10.1007/s00415-024-12384-3 · Cited by 27 · see citing works
Screening for severe drug-drug interactions in patients with multiple sclerosis: A comparison of three drug interaction databases
Hecker, M., Frahm, N., Bachmann, P., Debus, J. L., Haker, M.-C., Mashhadiakbar, P., Langhorst, S. E., Baldt, J., Streckenbach, B., Heidler, F., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.946351 · Cited by 27 · see citing works
Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone
Kwilasz, A., Todd, L., Duran-Malle, J. C., Schrama, A. E., Mitten, E., Larson, T. A., Clements, M., Harris, K. M., Litwiler, S., Wang, X.-H., et al. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112896 · Cited by 22 · see citing works
Depression in multiple sclerosis across the adult lifespan
Chan, C. K., Tian, F., Pimentel Maldonado, D., Mowry, E. M., & Fitzgerald, K. C. (2021) · Multiple Sclerosis Journal · doi:10.1177/1352458520979304 · Cited by 26 · see citing works
Risk of depression in multiple sclerosis across disease-modifying therapies
Longinetti, E., Frisell, T., Englund, S., Reutfors, J., Fang, F., & Piehl, F. (2021) · Multiple Sclerosis Journal · doi:10.1177/13524585211031128 · Cited by 26 · see citing works
The effect of therapeutic exercise on depressive symptoms in people with multiple sclerosis – A systematic review
Kyriakatis, G. M., Besios, T., & Lykou, P. M. (2022) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2022.104407 · Cited by 26 · see citing works
Clinical Practice Guidelines for the Detection and Treatment of Depression in Multiple Sclerosis
McIntosh, G. E., Liu, E. S., Allan, M., & Grech, L. (2023) · Neurology Clinical Practice · doi:10.1212/cpj.0000000000200154 · Cited by 28 · see citing works
Depression in persons with disabilities: a scoping review
Asdaq, S. M. B., Alshehri, S., Alajlan, S. A., Almutiri, A. A., & Alanazi, A. K. R. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1383078 · Cited by 29 · see citing works
Long-term Cognitive Outcomes and Socioprofessional Attainment in People With Multiple Sclerosis With Childhood Onset
Portaccio, E., Bellinvia, A., Razzolini, L., Pastò, L., Goretti, B., Niccolai, C., Fonderico, M., Zaffaroni, M., Pippolo, L., Moiola, L., et al. (2022) · Neurology · doi:10.1212/wnl.0000000000200115 · Cited by 24 · see citing works
Effects of different dietary interventions in multiple sclerosis: a systematic review of evidence from 2018 to 2022
Atabılen, B., & Akdevelıoğlu, Y. (2022) · Nutritional Neuroscience · doi:10.1080/1028415x.2022.2146843 · Cited by 24 · see citing works
The Impact of Epigallocatechin Gallate and Coconut Oil Treatment on Cortisol Activity and Depression in Multiple Sclerosis Patients
Platero, J. L., Cuerda‐Ballester, M., Sancho-Cantus, D., Benlloch, M., Cerón, J. M. C., Rubio, C. P., García-Pardo, M. P., López‐Rodriguez, M. M., & Ortí, J. E. D. L. R. (2021) · Life · doi:10.3390/life11040353 · Cited by 24 · see citing works
Multiple sclerosis by phenotype in Germany
Engelhard, J., Oleske, D. M., Schmitting, S., Wells, K. E., Talapala, S., & Barbato, L. M. (2021) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2021.103326 · Cited by 24 · see citing works
Keeping it together: The role of social integration on health and psychological well‐being among individuals with multiple sclerosis
Latinsky-Ortiz, E. M., & Strober, L. (2022) · Health and Social Care in the community · doi:10.1111/hsc.13800 · Cited by 25 · see citing works
The Influence of Depression and Anxiety on Neurological Disability in Multiple Sclerosis Patients
Văcăraș, V., Văcăraș, V., Nistor, C., Văcăraș, D., Opre, A. N., Blaga, P., & Muresanu, D. F. (2020) · Behavioural Neurology · doi:10.1155/2020/6738645 · Cited by 23 · see citing works
Depression, anxiety, and fear of COVID-19 in patients with multiple sclerosis in pandemic era: a cross-sectional study
Alirezaei, M., Eskandarieh, S., Sahraian, M. A., & Moghadasi, A. N. (2021) · Neurological Sciences · doi:10.1007/s10072-021-05612-5 · Cited by 22 · see citing works
Predicting Multiple Sclerosis Outcomes During the COVID-19 Stay-at-home Period: Observational Study Using Passively Sensed Behaviors and Digital Phenotyping
Chikersal, P., Venkatesh, S., Masown, K., Walker, E., Quraishi, D. A., Dey, A. K., Goel, M., & Xia, Z. (2022) · JMIR Mental Health · doi:10.2196/38495 · Cited by 20 · see citing works
Pharmacological management of depression in patients with multiple sclerosis
Carta, M. G., Paribello, P., Anastasia, A., Berardis, D. D., Nardi, A. E., & Fornaro, M. (2018) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2018.1516207 · Cited by 21 · see citing works
Self-citation
Vitamin B1 Intake in Multiple Sclerosis Patients and its Impact on Depression Presence: A Pilot Study
Ortí, J. E. D. L. R., Cuerda‐Ballester, M., Drehmer, E., Carrera‐Juliá, S., Motos-Muñoz, M., Cunha-Pérez, C., Benlloch, M., & López‐Rodriguez, M. M. (2020) · Nutrients · doi:10.3390/nu12092655 · Cited by 19 · see citing works
Adherence to and Persistence with Disease-Modifying Therapies for Multiple Sclerosis Over 24 Months: A Retrospective Claims Analysis
Pardo, G., Pineda, E. D., Ng, C. D., Bawa, K., Sheinson, D. M., & Bonine, N. G. (2022) · Neurology and Therapy · doi:10.1007/s40120-021-00319-3 · Cited by 19 · see citing works
The manifestation of affective symptoms in multiple sclerosis and discussion of the currently available diagnostic assessment tools
Filser, M., Buchner, A., Fink, G. R., Gold, S. M., & Penner, I. (2022) · Journal of Neurology · doi:10.1007/s00415-022-11359-6 · Cited by 18 · see citing works
Neuro-immune crosstalk in depressive symptoms of multiple sclerosis
Wang, C., Zhou, Y., & Feinstein, A. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106005 · Cited by 19 · see citing works
Cognitive impairment in multiple sclerosis: “classic” knowledge and recent acquisitions
Piacentini, C., Argento, O., & Nocentini, U. (2023) · Arquivos de Neuro-Psiquiatria · doi:10.1055/s-0043-1763485 · Cited by 18 · see citing works
Nogo-A antibody delivery through the olfactory mucosa mitigates experimental autoimmune encephalomyelitis in the mouse CNS
Pernet, V., Joly, S., Spiegel, S., Meli, I., Idriss, S., Maigler, F., Mdzomba, J. B., Roenneke, A. K., Franceschini, A., Silvestri, L., et al. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01588-7 · Cited by 18 · see citing works
Treating depression in clinical practice: new insights on the multidisciplinary use of trazodone
Albert, U., Tomasetti, C., Marra, C., Neviani, F., Pirani, A., Taddeo, D., Zanetti, O. O., & Maina, G. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1207621 · Cited by 18 · see citing works
Non-infectious comorbidity in patients with multiple sclerosis: A national cohort study in Sweden
Castelo‐Branco, A., Chiesa, F., Bengtsson, C., Lee, S., Minton, N., Niemcryk, S. J., Lindholm, A., Rosenlund, M., Piehl, F., & Montgomery, S. (2020) · Multiple Sclerosis Journal - Experimental Translational and Clinical · doi:10.1177/2055217320947761 · Cited by 18 · see citing works
Associations of demographic and clinical factors with depression over 2.5-years in an international prospective cohort of people living with MS
Simpson, S., Taylor, K. L., Jelinek, G. A., Livera, A. M. D., Brown, C. R., O’Kearney, E., Neate, S. L., Bevens, W., & Weiland, T. J. (2019) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2019.02.014 · Cited by 18 · see citing works
Possible role of the NLRP3 inflammasome and the gut–brain axis in multiple sclerosis‐related depression
Maciak, K., Dziedzic, A., & Saluk, J. (2022) · The FASEB Journal · doi:10.1096/fj.202201348r · Cited by 18 · see citing works
Interventions to Improve Quality of Life in Multiple Sclerosis: New Opportunities and Key Talking Points
Faraclas, E. (2023) · Degenerative Neurological and Neuromuscular Disease · doi:10.2147/dnnd.s395733 · Cited by 17 · see citing works
A Prospective, Observational, Cohort Study to Assess the Efficacy and Safety of Prolonged-Release Fampridine in Cognition, Fatigue, Depression, and Quality of Life in Multiple Sclerosis Patients: The FAMILY Study
Mitsikostas, D. D., Doskas, T. K., Gkatzonis, S., Fakas, N., Maltezou, M., Papadopoulos, D., Gourgioti, R., & Mitsias, P. D. (2021) · Advances in Therapy · doi:10.1007/s12325-020-01606-5 · Cited by 17 · see citing works
Multiple Sclerosis and the Endogenous Opioid System
Dworsky-Fried, Z., Chadwick, C. I., Kerr, B. J., & Taylor, A. M. W. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.741503 · Cited by 17 · see citing works
Low‑field magnetic stimulation improved cuprizone‑induced depression‑like symptoms and demyelination in female mice
Mooshekhian, A., Sandini, T. M., Wei, Z., van Bruggen, R., Li, H., Li, X., & Zhang, Y. (2022) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2022.11133 · Cited by 16 · see citing works
Serum and CSF Biomarkers Predict Active Early Cognitive Decline Rather Than Established Cognitive Impairment at the Moment of RRMS Diagnosis
Tiu, V. E., Popescu, B. O., Enache, I. I., Tiu, C., Terecoasă, E., & Panea, C. (2022) · Diagnostics · doi:10.3390/diagnostics12112571 · Cited by 16 · see citing works
Clinical correlates of state and trait anxiety in multiple sclerosis
Menculini, G., Gentili, L., Gaetani, L., Mancini, A., Sperandei, S., Sabatino, E. D., Chipi, E., Salvadori, N., Tortorella, A. A. V., Parnetti, L., et al. (2022) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2022.104431 · Cited by 16 · see citing works
Pulse steroid therapy in multiple sclerosis and mood changes: An exploratory prospective study
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Authors: Patten, S. B., Marrie, R. A., & Carta, M. G.
Affiliations: University of Calgary (CA)
University of Manitoba (CA)
University of Cagliari (IT)
Corresponding author: Patten, Scott B.
ORCID: Patten, Scott B.
Marrie, Ruth Ann
Carta, Mauro G.
Venue: International Review of Psychiatry
Publisher: Informa UK Limited
Published: 2017-07-06
Volume: 29
Issue: 5
Pages: 463-472
ISSN: 0954-0261 (ISSN-L)
1369-1627
DOI: 10.1080/09540261.2017.1322555
OpenAlex: W2726625509
Cited by: 262
References: 103
Citations by year: 2026: 16 · 2025: 22 · 2024: 34 · 2023: 33 · 2022: 43 · 2021: 34 · 2020: 57 · 2019: 11 · 2018: 7 · 2017: 2
FWCI: 3.36
Type: journal article
Language: en
Open access: closed
Locations: International Review of Psychiatry (publishedVersion)
PubMed (publishedVersion)
UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion, public-domain)
Topics: Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: depression, multiple sclerosis, prevalence, etiology, lesion burden, brain atrophy, stressors, risk factors, depression screening, depression treatment, cognitive behavioral therapy, antidepressants, measurement scales
MeSH terms: Adult, Antidepressive Agents, Depression, Female, Humans, Male, Multiple Sclerosis, Brief Psychiatric Rating Scale, Cognitive Behavioral Therapy, Prevalence

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