Effects of polydextrose supplementation on different faecal parameters in healthy volunteers
Abstract
The beneficial effects of prebiotics on bowel health were thoroughly investigated. The aim of the study was to show prebiotic effects of polydextrose (PDX). A placebo-controlled, randomized intervention study with PDX supplementation (8 g/day) was conducted in 45 healthy subjects. The effects of PDX on stool weight, orofaecal transit time, consistency of stool (Bristol stool form scale), short-chain fatty acid production, pH value, neutral sterol and bile acid excretion and faecal microbiota were evaluated. It was found that supplementation of PDX shortened the orofaecal transit time significantly. Furthermore, ingestion of PDX resulted in a decreased pH value and in significant changes in bile acid and neutral sterol excretion. PDX had no effects on stool weight, concentrations of the main short-chain fatty acids (acetate, propionate) and faecal contents of lactic acid bacteria and bifidobacteria. In conclusion, PDX is able to shorten the orofaecal transit time and to improve stool consistency in subjects suffering from constipation. [corrected]
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A yogurt containing polydextrose reduces oro-faecal transit time and improves fecal consistency.
“Hengst et al. [6] reported that a yogurt containing polydextrose reduced oro-faecal transit time, as well as an improvement in the fecal consistency.”
Polydextrose promotes a shorter time passing through the intestines and improves stool consistency.
“It presents the same properties of fibers and promotes a shorter time passing through the intestines and improves the consistency of the stool [5,6].”
Cites
Stool form scale as a useful guide to intestinal transit time
Lewis, S. J., & Heaton, K. W. (1997) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529709011203 · Cited by 3,244 · see citing works
Dietary modulation of the human colonic microbiota: updating the concept of prebiotics
Gibson, G. R., Probert, H. M., Loo, J. V., Rastall, R. A., & Roberfroid, M. B. (2004) · Nutrition Research Reviews · doi:10.1079/nrr200479 · Cited by 2,539 · see citing works
Armstrong, B. K., & Doll, R. (1975) · International Journal of Cancer · doi:10.1002/ijc.2910150411 · Cited by 2,161 · see citing works
Manz, W., Amann, R., Ludwig, W., Wagner, M., & SCHLEIFER, K. H. (1992) · Systematic and Applied Microbiology · doi:10.1016/s0723-2020(11)80121-9 · Cited by 2,044 · see citing works
Prebiotic digestion and fermentation.
Cummings, J., Macfarlane, G., & Englyst, H. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.2.415s · Cited by 664 · see citing works
Valeur, N., Engel, P. A., Carbajal, N., Connolly, E., & Ladefoged, K. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.2.1176-1181.2004 · Cited by 343 · see citing works
Studies on the effects of polydextrose intake on physiologic functions in Chinese people
Jie, Z., Bang-yao, L., Ming-jie, X., Hai-wei, L., Zu-kang, Z., Ting-song, W., & Craig, S. A. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.6.1503 · Cited by 207 · see citing works
Govers, M. J., Gannon, N. J., Dunshea, F. R., Gibson, P. R., & Muir, J. G. (1999) · Gut · doi:10.1136/gut.45.6.840 · Cited by 183 · see citing works
Probert, H. M., Apajalahti, J. H. A., Rautonen, N., Stowell, J., & Gibson, G. R. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.8.4505-4511.2004 · Cited by 147 · see citing works
van der Waaij, L. A., Harmsen, H. J. M., Madjipour, M., Kroese, F. G. M., Zwiers, M., van Dullemen, H. M., de Boer, N. K., Welling, G. W., & Jansen, P. L. M. (2005) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000179212.80778.d3 · Cited by 141 · see citing works
Klein, A., Friedrich, U., Vogelsang, H., & Jahreis, G. (2007) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602761 · Cited by 136 · see citing works
Self-citationTHE TRANSFORMATION OF CHOLESTEROL TO COPROSTANOL
Rosenfeld, R. S., Fukushima, D. K., HELLMAN, L., et al. (1954) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71221-0 · Cited by 126 · see citing works
Kandell, R. L., & Bernstein, C. (1991) · Nutrition and Cancer · doi:10.1080/01635589109514161 · Cited by 120 · see citing works
Mechanism of cholesterol reduction to coprostanol by Eubacterium coprostanoligenes ATCC 51222
Ren, D., Li, L., Schwabacher, A. W., Young, J. W., & Beitz, D. C. (1996) · Steroids · doi:10.1016/0039-128x(95)00173-n · Cited by 116 · see citing works
Intestinal flora and human health.
MITSUOKA, T. (1996) · PubMed · Cited by 111 · see citing works
Cholesterol Metabolism Is Affected by Calcium Phosphate Supplementation in Humans
Ditscheid, B., Keller, S., & Jahreis, G. (2005) · Journal of Nutrition · doi:10.1093/jn/135.7.1678 · Cited by 107 · see citing works
Self-citationResistant starch in the diet increases breath hydrogen and serum acetate in human subjects
Muir, J., Lu, Z., Young, G. P., Cameron‐Smith, D., Collier, G., & O’Dea, K. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/61.4.792 · Cited by 106 · see citing works
Keller, S., & Jahreis, G. (2004) · Journal of Chromatography B · doi:10.1016/j.jchromb.2004.09.046 · Cited by 102 · see citing works
Self-citationPeuranen, S., Tiihonen, K., Apajalahti, J., et al. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041114 · Cited by 88 · see citing works
Colonic Function and Fermentation in Men Consuming High Fiber Diets
Fleming, S. E., Marthinsen, D., & Kuhnlein, H. V. (1983) · Journal of Nutrition · doi:10.1093/jn/113.12.2535 · Cited by 78 · see citing works
Polydextrose as soluble fiber: physiological and analytical aspects
Craig, S. A. S., Holden, J. F., Troup, J. P., et al. (1998) · Cereal Foods World · Cited by 65 · see citing works
Microbiota Composition of the Intestinal Mucosa: Association with Fecal Microbiota?
Ouwehand, A. C., Salminen, S., Arvola, T., Ruuska, T. H., & Isolauri, E. (2004) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2004.tb03544.x · Cited by 61 · see citing works
Effect of polydextrose on intestinal microbes and immune functions in pigs
Fava, F., Mäkivuokko, H., Siljander-Rasi, H., Putaala, H., Tiihonen, K., Stowell, J. D., Tuohy, K. M., Gibson, G. R., & Rautonen, N. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507691818 · Cited by 60 · see citing works
Intestinal microbial conversion of cholesterol to coprostanol in man
Midtvedt, T., Lingaas, E., Carlstedt‐Duke, B., et al. (1990) · Apmis · doi:10.1111/j.1699-0463.1990.tb05004.x · Cited by 59 · see citing works
Gastrointestinal effects and energy value of polydextrose in healthy nonobese men
Achour, L., Flourié, B., Briet, F., Pellier, P., Marteau, P., & Rambaud, J. (1994) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/59.6.1362 · Cited by 52 · see citing works
Endo, K., Kumemura, M., NAKAMURA, K., et al. (1991) · Bifidobacteria and Microflora · doi:10.12938/bifidus1982.10.1_53 · Cited by 47 · see citing works
Bartram, H.-P., Scheppach, W. M., Heid, C., Fabian, C., & Kasper, H. (1991) · PubMed · Cited by 41 · see citing works
Tiihonen, K., Suomalainen, T., Tynkkynen, S., & Rautonen, N. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507825141 · Cited by 26 · see citing works
Nakagawa, Y., Okamatsu, H., & Fujii, Y. (1990) · Nippon Eiyo Shokuryo Gakkaishi · doi:10.4327/jsnfs.43.95 · Cited by 14 · see citing works
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Fiber and prebiotics: Mechanisms and health benefits
Slavin, J. (2013) · Nutrients · doi:10.3390/nu5041417 · Cited by 2,340 · see citing works
Raninen, K., Lappi, J., Mykkänen, H., & Poutanen, K. (2011) · Nutrition Reviews · doi:10.1111/j.1753-4887.2010.00358.x · Cited by 254 · see citing works
Magro, D. O., de Oliveira, L. M. R., Bernasconi, I., de Souza Ruela, M., Credidio, L., Barcelos, I. K., Leal, R. F., Ayrizono, M. D. L. S., Fagundes, J. J., Teixeira, L. D. B., et al. (2014) · Nutrition Journal · doi:10.1186/1475-2891-13-75 · Cited by 105 · see citing works
Ibarra, A., Pelipyagina, T., Rueffer, M., Evans, M., & Ouwehand, A. C. (2019) · Nutrients · doi:10.3390/nu11020439 · Cited by 22 · see citing works
“However, there are few studies on the effects of PDX on shortening total or colonic transit time (CTT), and the results have been inconclusive [13,18,19].”
Background
- Authors
- Hengst, C., Ptok, S., Roessler, A., Fechner, A., & Jahreis, G.
- Affiliations
- Friedrich Schiller University Jena (DE)
- Corresponding author
- Jahreis, Gerhard
- Venue
- International Journal of Food Sciences and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2009-01
- Volume
- 60
- Issue
- sup5
- Pages
- 96-105
- ISSN
- 0963-7486 (ISSN-L)
- 1465-3478
- OpenAlex
- W2069649749
- Cited by
- 63
- References
- 29
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 6 · 2022: 5 · 2021: 3 · 2019: 5 · 2018: 2 · 2017: 5 · 2016: 6 · 2015: 4 · 2014: 4 · 2013: 6 · 2012: 5
- FWCI
- 4.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Food Sciences and Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- polydextrose, prebiotics, stool consistency, short-chain fatty acids, bile acid excretion, neutral sterols, fecal microbiota, lactic acid bacteria, Bifidobacterium, constipation, dietary supplementation
- MeSH terms
- Adult, Aged, Bifidobacterium, Bile Acids and Salts, Constipation, Defecation, Diet, Fatty Acids, Volatile, Feces, Female, Gastrointestinal Transit, Glucans, Humans, Hydrogen-Ion Concentration, Lactobacillus acidophilus, Male, Middle Aged, Sterols, Colony Count, Microbial, Diet Records, Body Mass Index, Gastrointestinal Tract, Young Adult, Prebiotics
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