Cited by 15Seaweed-derived Bioactive CompoundsAlgal biology and biofuel productionProtein Hydrolysis and Bioactive Peptides

Research progress in microalgae nutrients: Emerging extraction and purification technologies, digestive behavior, and potential effects on human gut

Open access
Zhou, Jianjun, Wang, Min, Grimi, Nabil, Dar, Basharat N., Calvo-Lerma, Joaquim, Barba, Francisco J.·2024·Critical Reviews in Food Science and Nutrition

Abstract

Microalgae contain a diverse range of high-value compounds that can be utilized directly or fractionated to obtain components with even greater value-added potential. With the use of microalgae for food and medical purposes, there is a growing interest in their digestive properties and impact on human gut health. The extraction, separation, and purification of these components are key processes in the industrial application of microalgae. Innovative technologies used to extract and purify microalgal high-added-value compounds are key for their efficient utilization and evaluation. This review's comprehensive literature review was performed to highlight the main high-added-value microalgal components. The technologies for obtaining bioactive compounds from microalgae are being developed rapidly, various innovative, efficient, green separation and purification technologies are emerging, thus helping in the scaling-up and subsequent commercialization of microalgae products. Finally, the digestive behavior of microalgae nutrients and their health effects on the human gut microbiota were discussed. Microalgal nutrients exhibit favorable digestive properties and certain components have been shown to benefit gut microbes. The reality that must be faced is that multiple processes are still required for microalgae raw materials to final usable products, involving energy, time consumption and loss of ingredients, which still face challenges.

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Crossref · 10.1080/10408398.2023.2237586

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164 of 164 references verified0 citation errors · 0 not checkable

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  • Microalgae-derived bioactives beneficially modulate gut microbiota composition and function.

    “Increasing evidence suggests that microalgae-derived bioactives beneficially modulate gut microbiota composition and function, thereby supporting overall health [58,59].”

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Authors
Zhou, J., Wang, M., Grimi, N., Dar, B. N., Calvo-Lerma, J., & Barba, F. J.
Affiliations
  • Consejo Superior de Investigaciones Científicas (ES)
  • Université de Technologie de Compiègne (FR)
  • Islamic University of Science and Technology (IN)
  • Instituto Universitario de Ingeniería para el Desarrollo (IU-IAD), Universitat Politècnica de València, Valencia, Spain
  • Universitat de València (ES)
Corresponding author
  • Grimi, Nabil
  • Dar, Basharat N.
Venue
Critical Reviews in Food Science and Nutrition
Published
2023-07-25
Volume
64
Issue
31
Pages
11375-11395
ISSN
  • 1040-8398 (ISSN-L)
  • 1549-7852
OpenAlex
W4385230720
Cited by
15
References
164
Citations by year
2026: 3 · 2025: 6 · 2024: 6
FWCI
0.38
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Critical Reviews in Food Science and Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
  • Repository of Digital Objects for Teaching Research and Culture (University of Valencia) (submittedVersion, cc-by-nc)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
  • Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
Keywords
microalgae, bioactive compounds, extraction methods, separation and purification, gut microbiota, digestive properties, gut health, value-added chemicals
MeSH terms
Gastrointestinal Microbiome, Nutrients, Digestion, Humans, Gastrointestinal Tract, Microalgae

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