Alzheimers’ disease and caregiving: a meta-analytic review comparing the mental health of primary carers to controls
Abstract
Objectives To quantitatively review the literature comparing depressed mood, anxiety and psychological distress in caregivers (CGs) of older adults with Alzheimer's disease (AD) with non-caregivers (NCGs) Methods: Eighteen independent studies comparing AD CGs (N = 2378) with NCGs (N = 70,035) were evaluated in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Standardised mean differences (Hedges' g) with associated 95% confidence intervals and p-values were calculated using a random-effects model. Results Studies generally conformed to STROBE criteria in terms of their methodological and procedural detail, although data management issues that may contribute to methodological bias were identified. Pooled effect estimates revealed medium to large group differences in depression (g w = 1.01 [CI: 0.73, 1.29] p w = 0.64 [CI: 0.39, 0.89] p w = 1.58 [CI: 1.11, 2.05], p Discussion Caregivers of patients with AD experience poor mental health in comparison to the general population, with female caregivers being disproportionately affected. Further exploration of the psychosocial variables that contribute to these group differences is needed to inform effective support services and, in turn, help caregivers manage the emotional demands of AD.
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A meta-analysis reported that caregivers of people with dementia were significantly more likely to experience depression and anxiety than non-caregivers.
“A meta‐analysis reported that caregivers of people with dementia were significantly more likely to experience depression and anxiety than non‐caregivers. 452”
From 2024 Alzheimer's disease facts and figures (2024) · cites this paper as [452]
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2023 Alzheimer's disease facts and figures
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2024 Alzheimer's disease facts and figures
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2019 Alzheimer’s disease facts and figures.
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2020 Alzheimer's disease facts and figures
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2022 Alzheimer's disease facts and figures
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2021 Alzheimer's disease facts and figures
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2018 Alzheimer's disease facts and figures
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2025 Alzheimer's disease facts and figures
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Dementia Caregiving Experiences and Health Across Geographic Contexts by Race and Ethnicity
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Sex and gender differences in health and disease. Part II. Clinical and medical-social
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Prevalence and Associated Factors with Poor Sleep Quality in Non-Professional Caregivers
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Alzheimer’s Disease and Other Dementias
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Voluntary Registries to Support Improved Interaction Between Police and People Living with Dementia
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Women’s brain health and brain capital
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Transcultural Adaptation of the “ Caregiver Guilt Questionnaire ” (CGQ)
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- Authors
- Ma, M., Dorstyn, D., Ward, L., & Prentice, S.
- Affiliations
- The University of Adelaide (AU)
- Corresponding author
- Dorstyn, Diana
- Venue
- Aging & Mental Health
- Publisher
- Informa UK Limited
- Published
- 2017-09-05
- Volume
- 22
- Issue
- 11
- Pages
- 1395-1405
- ISSN
- 1360-7863 (ISSN-L)
- 1364-6915
- OpenAlex
- W2751156782
- Cited by
- 133
- References
- 123
- Citations by year
- 2026: 9 · 2025: 19 · 2024: 17 · 2023: 17 · 2022: 21 · 2021: 23 · 2020: 13 · 2019: 7 · 2018: 6 · 2017: 1
- FWCI
- 6.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Aging & Mental Health (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Dementia Training Australia
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
- Keywords
- Alzheimer's disease, caregiver mental health, primary caregivers, depression, anxiety, psychological distress, gender differences, older adults, caregiver burden
- MeSH terms
- Alzheimer Disease, Anxiety Disorders, Depressive Disorder, Humans, Stress, Psychological, Caregivers, Observational Studies as Topic
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