Perfluorooctane Sulfonate (PFOS) Induces Reactive Oxygen Species (ROS) Production in Human Microvascular Endothelial Cells: Role in Endothelial Permeability

Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings

Lau, C., Anitole, K., Hodes, C., Lai, D., Pfahles-Hutchens, A., & Seed, J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm128 · Cited by 2,620

Free radicals, antioxidants, and human disease: where are we now?

Halliwell, B. B., Gutteridge, J. M. C., & Cross, C. E. (1992) · PubMed · Cited by 2,156

Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers

Olsen, G. W., Burris, J. M., Ehresman, D. J., Froehlich, J. W., Seacat, A. M., Butenhoff, J. L., & Zobel, L. R. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10009 · Cited by 2,049

Spin Trapping: ESR parameters of spin adducts 1474 1528V

Buettner, G. R. (1987) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(87)80033-3 · Cited by 1,827

Signaling Mechanisms Regulating Endothelial Permeability

Mehta, D., & Malik, A. B. (2005) · Physiological Reviews · doi:10.1152/physrev.00012.2005 · Cited by 1,754

Polyfluoroalkyl Chemicals in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and Comparisons with NHANES 1999–2000

Calafat, A. M., Wong, L.-Y., Kuklenyik, Z., Reidy, J. A., & Needham, L. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10598 · Cited by 1,247

A causal role for uric acid in fructose-induced metabolic syndrome

Nakagawa, T., Hu, H., Zharikov, S. I., Tuttle, K. R., Short, R., Glushakova, O. Y., Ouyang, X., Feig, D. I., Block, E. R., Herrera-Acosta, J., et al. (2005) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00140.2005 · Cited by 1,111

Free Radicals and Antioxidants in the Year 2000: A Historical Look to the Future

Gutteridge, J. M. C., & Halliwell, B. B. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06182.x · Cited by 1,018

Oxidant stress and endothelial cell dysfunction

Lum, H., & Roebuck, K. A. (2001) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.2001.280.4.c719 · Cited by 833

Metal-induced oxidative stress and signal transduction

Leonard, S. S., Harris, G. K., & Shi, X. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.09.010 · Cited by 663

Endocrine disrupters as obesogens

Grün, F., & Blumberg, B. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.02.018 · Cited by 586

Toxicology of perfluorinated compounds

Stahl, T., Mattern, D., & Brunn, H. (2011) · Environmental Sciences Europe · doi:10.1186/2190-4715-23-38 · Cited by 432

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

Goodson, W. H., Lowe, L. J., Carpenter, D. O., Gilbertson, M., Ali, A. M., Salsamendi, A. L. D. C., Lasfar, A., Carnero, A., Azqueta, A., Amedei, A., et al. (2015) · Carcinogenesis · doi:10.1093/carcin/bgv039 · Cited by 336

Assessing the human health risks of perfluorooctane sulfonate by in vivo and in vitro studies

Zeng, Z., Song, B., Xiao, R., Zeng, G., Gong, J., Chen, M., Xu, P., Zhang, P., Shen, M., & Yi, H. (2019) · Environment International · doi:10.1016/j.envint.2019.03.002 · Cited by 306

Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome

Wang, L.-Q., Liu, T., Yang, S., Sun, L., Zhao, Z., Li, L.-Y., She, Y., Zheng, Y.-Y., Ye, X., Bao, Q., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23201-0 · Cited by 270

Absorption, Distribution, and Toxicity of Per- and Polyfluoroalkyl Substances (PFAS) in the Brain: a Review

Cao, Y., & Ng, C. (2021) · Environmental Science: Processes & Impacts · doi:10.1039/d1em00228g · Cited by 250

The effects of environmental chemicals on renal function

Kataria, A., Trasande, L., & Trachtman, H. (2015) · Nature Reviews Nephrology · doi:10.1038/nrneph.2015.94 · Cited by 252

Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health: A Scoping Review

Stanifer, J. W., Stapleton, H. M., Souma, T., Wittmer, A., Zhao, X., & Boulware, L. E. (2018) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.04670418 · Cited by 233

A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior

Starnes, H. M., Rock, K. D., Jackson, T. W., & Belcher, S. M. (2022) · Frontiers in Toxicology · doi:10.3389/ftox.2022.881584 · Cited by 166

Perfluoroalkyl Chemicals and Chronic Kidney Disease in US Adults

Shankar, A., Xiao, J., & Ducatman, A. (2011) · American Journal of Epidemiology · doi:10.1093/aje/kwr171 · Cited by 166

Perfluoroalkyl substances (PFASs) influence the structure and function of soil bacterial community: Greenhouse experiment

Qiao, W., Xie, Z., Zhang, Y., Liu, X., Xie, S., Huang, J., & Yu, L. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.06.113 · Cited by 162

Exposure to Perfluoroalkyl Acids and Markers of Kidney Function Among Children and Adolescents Living Near a Chemical Plant

Watkins, D. J., Josson, J., Elston, B., Bartell, S. M., Shin, H.-M., Vieira, V. M., Savitz, D. A., Fletcher, T., & Wellenius, G. A. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1205838 · Cited by 158

Effects of endocrine disrupting chemicals on gonad development: Mechanistic insights from fish and mammals

Delbès, G., Blázquez, M., Fernandino, J. I., Grigorova, P., Hales, B. F., Metcalfe, C. D., Navarro‐Martín, L., Parent, L., Robaire, B., Rwigemera, A., et al. (2021) · Environmental Research · doi:10.1016/j.envres.2021.112040 · Cited by 152

Association between perfluoroalkyl acids and kidney function in a cross-sectional study of adolescents

Kataria, A., Trachtman, H., Málaga-Diéguez, L., & Trasande, L. (2015) · Environmental Health · doi:10.1186/s12940-015-0077-9 · Cited by 133

Short-chain per- and polyfluoralkyl substances (PFAS) effects on oxidative stress biomarkers in human liver, kidney, muscle, and microglia cell lines

Solan, M. E., Koperski, C. P., Senthilkumar, S., & Lavado, R. (2023) · Environmental Research · doi:10.1016/j.envres.2023.115424 · Cited by 126

Perfluoroalkyl substances, bone density, and cardio-metabolic risk factors in obese 8–12 year old children: A pilot study

Khalil, N., Ebert, J. R., Honda, M., Lee, M., Nahhas, R. W., Koskela, A., Hangartner, T. N., & Kannan, K. (2017) · Environmental Research · doi:10.1016/j.envres.2017.10.014 · Cited by 123

Cell Permeability, Migration, and Reactive Oxygen Species Induced by Multiwalled Carbon Nanotubes in Human Microvascular Endothelial Cells

Pacurari, M., Qian, Y., Fu, W., Schwegler‐Berry, D., Ding, M., Castranova, V., & Guo, N. L. (2011) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2011.615110 · Cited by 118

Associations of per- and polyfluoroalkyl substances (PFAS) and their mixture with oxidative stress biomarkers during pregnancy

Taibl, K. R., Schantz, S. L., Aung, M. T., Padula, A. M., Geiger, S. D., Smith, S. C., Park, J.-S., Milne, G. L., Robinson, J. F., Woodruff, T. J., et al. (2022) · Environment International · doi:10.1016/j.envint.2022.107541 · Cited by 117

Associations between repeated measure of plasma perfluoroalkyl substances and cardiometabolic risk factors

Donat‐Vargas, C., Bergdahl, I. A., Tornevi, A., Wennberg, M., Sommar, J. N., Koponen, J. M., Kiviranta, H., & Åkesson, A. (2019) · Environment International · doi:10.1016/j.envint.2019.01.007 · Cited by 110

A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)

Wen, Z.-J., Wei, Y.-J., Zhang, Y., & Zhang, Y. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03477-5 · Cited by 116

Perfluorooctanoic Acid and Cardiovascular Disease in US Adults

Shankar, A., Xiao, J., & DUCATMAN, A. M. (2012) · Archives of Internal Medicine · doi:10.1001/archinternmed.2012.3393 · Cited by 110

PFOS induces adipogenesis and glucose uptake in association with activation of Nrf2 signaling pathway

Xu, J., Shimpi, P. C., Armstrong, L. E., Salter, D. M., & Slitt, A. L. (2015) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2015.11.002 · Cited by 106

Perfluorinated Compounds

Lau, C. S. (2012) · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions · doi:10.1007/978-3-7643-8340-4_3 · Cited by 106

Environmental Impacts on Cardiovascular Health and Biology: An Overview

Blaustein, J. R., Quisel, M. J., Hamburg, N. M., & Wittkopp, S. (2024) · Circulation Research · doi:10.1161/circresaha.123.323613 · Cited by 103

Association between levels of serum perfluorooctane sulfate and carotid artery intima–media thickness in adolescents and young adults

Lin, C., Lin, L., Wen, T.-W., Lien, G., Chien, K., Hsu, S. H.-J., Liao, C., Sung, F.-C., Chen, P., & Su, T. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.04.042 · Cited by 101

Effects of Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonic Acid (PFOS) on Soil Microbial Community

Xu, R., Tao, W., Lin, H., Huang, D., Su, P., Gao, P., Sun, X., Yang, Z., & Sun, W. (2021) · Microbial Ecology · doi:10.1007/s00248-021-01808-6 · Cited by 100

Perfluorooctane Sulfonate Induces Apoptosis of Cerebellar Granule Cells via a ROS-dependent Protein Kinase C Signaling Pathway

Lee, H.-G., Lee, Y. J., & Yang, J.-H. (2012) · NeuroToxicology · doi:10.1016/j.neuro.2012.01.017 · Cited by 97

Associations between perfluoroalkyl substances and lipid profile in a highly exposed young adult population in the Veneto Region

Canova, C., Barbieri, G., Jeddi, M. Z., Gion, M., Fabricio, A. S. C., Daprà, F., Russo, F., Fletcher, T., & Pitter, G. (2020) · Environment International · doi:10.1016/j.envint.2020.106117 · Cited by 101

Early pregnancy serum levels of perfluoroalkyl substances and risk of preeclampsia in Swedish women

Wikström, S., Lindh, C. H., Shu, H., & Bornehag, C. (2019) · Scientific Reports · doi:10.1038/s41598-019-45483-7 · Cited by 94

Neurotoxicity of per- and polyfluoroalkyl substances: Evidence and future directions

Bharal, B., Ruchitha, C., Kumar, P., Pandey, R., Rachamalla, M., Niyogi, S., Naidu, R., & Kaundal, R. K. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.176941 · Cited by 95

PFOA and PFOS promote diabetic renal injury in vitro by impairing the metabolisms of amino acids and purines

Gong, X., Yang, C., Hong, Y., Chung, A. C. K., & Cai, Z. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.04.208 · Cited by 89

Associations of Perfluoroalkyl and Polyfluoroalkyl Substances With Incident Diabetes and Microvascular Disease

Cárdenas, A., Hivert, M., Gold, D. R., Hauser, R. B., Kleinman, K., Lin, P. D., Fleisch, A. F., Calafat, A. M., Ye, X., Webster, T. F., et al. (2019) · Diabetes Care · doi:10.2337/dc18-2254 · Cited by 91

Acute PFOA exposure promotes epigenomic alterations in mouse kidney tissues

Rashid, F., Ramakrishnan, A., Fields, C. J., & Irudayaraj, J. (2020) · Toxicology Reports · doi:10.1016/j.toxrep.2019.12.010 · Cited by 91

Perfluorooctanoic acid disrupts gap junction intercellular communication and induces reactive oxygen species formation and apoptosis in mouse ovaries

López‐Arellano, P., López‐Arellano, K., Luna, J., Flores, D., Jiménez-Salazar, J. E., Gavia, G., Teteltitla, M., Rodríguez-Mercado, J. J., Domínguez, A., Casas, E., et al. (2018) · Environmental Toxicology · doi:10.1002/tox.22661 · Cited by 85

Considering environmental exposures to per- and polyfluoroalkyl substances (PFAS) as risk factors for hypertensive disorders of pregnancy

Erinc, A., Davis, M. B., Padmanabhan, V., Langen, E. S., & Goodrich, J. M. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111113 · Cited by 85

Early-pregnancy plasma per- and polyfluoroalkyl substance (PFAS) concentrations and hypertensive disorders of pregnancy in the project viva cohort

Preston, E. V., Hivert, M.-F., Fleisch, A. F., Calafat, A. M., Sagiv, S. K., Perng, W., Rifas-Shiman, S. L., Chavarro, J. E., Oken, E., Zota, A. R., et al. (2022) · Environment International · doi:10.1016/j.envint.2022.107335 · Cited by 78

Perfluoroalkyl Chemicals in Neurological Health and Disease: Human Concerns and Animal Models

Piekarski, D., Diaz, K., & McNerney, M. (2020) · NeuroToxicology · doi:10.1016/j.neuro.2020.01.001 · Cited by 76

The association between total serum isomers of per- and polyfluoroalkyl substances, lipid profiles, and the DNA oxidative/nitrative stress biomarkers in middle-aged Taiwanese adults

Lin, C., Lee, H., Hwang, Y., & Su, T. (2019) · Environmental Research · doi:10.1016/j.envres.2019.109064 · Cited by 73

Effect of perfluorooctane sulfonate on viability, maturation and gap junctional intercellular communication of porcine oocytes in vitro

Domínguez, A., Salazar, Z., Arenas, E., Betancourt, M., Ducolomb, Y., González‐Márquez, H., Casas, E., Teteltitla, M., & Bonilla, E. (2016) · Toxicology in Vitro · doi:10.1016/j.tiv.2016.05.011 · Cited by 71

Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive oxygen species‐mediated mitochondrion‐dependent pathway

Mao, Z., Xia, W., Wang, J., Chen, T., Zeng, Q., Xu, B., Li, W., Chen, X., & Xu, S. (2012) · Journal of Applied Toxicology · doi:10.1002/jat.2785 · Cited by 69

Early life perfluorooctanesulphonic acid (PFOS) exposure impairs zebrafish organogenesis

Chen, J., Tanguay, R. L., Tal, T. L., Gai, Z., Ma, X., Bai, C., Tilton, S. C., Jin, D., Yang, D., Huang, C., et al. (2014) · Aquatic Toxicology · doi:10.1016/j.aquatox.2014.03.005 · Cited by 69

Per- and Polyfluoroalkyl Substances and Incident Hypertension in Multi-Racial/Ethnic Women: The Study of Women's Health Across the Nation

Ding, N., Karvonen-Gutierrez, C. A., Mukherjee, B., Calafat, A. M., Harlow, S. D., & Park, S. K. (2022) · Hypertension · doi:10.1161/hypertensionaha.121.18809 · Cited by 64

Negative Association Between Serum Perfluorooctane Sulfate Concentration and Bone Mineral Density in US Premenopausal Women: NHANES, 2005–2008

Lin, L., Wen, L., Su, T., Chen, P., & Lin, C. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-3409 · Cited by 64

Oxidative stress and apotosis to Zebrafish (Danio rerio) embryos exposed to perfluorooctane sulfonate (PFOS) and ZnO nanoparticles

Du, J., Cai, J., Wang, S., & You, H. (2017) · International Journal of Occupational Medicine and Environmental Health · doi:10.13075/ijomeh.1896.00669 · Cited by 63

Serum concentrations of per- and polyfluoroalkyl substances and risk of renal cell carcinoma in the Multiethnic Cohort Study

Rhee, J., Chang, V. C., Cheng, I. C., Calafat, A. M., Botelho, J. C., Shearer, J. J., Sampson, J. N., Setiawan, V. W., Wilkens, L. R., Silverman, D. T., et al. (2023) · Environment International · doi:10.1016/j.envint.2023.108197 · Cited by 63

Perfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma Inactivation

Wen, L.-L., Lin, C., Chou, H., Chang, C., Lo, H.-Y., & Juan, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155190 · Cited by 64

Ecotoxicoproteomics in gills of the sentinel fish species, Cottus gobio, exposed to perfluorooctane sulfonate (PFOS)

Dorts, J., Kestemont, P., Marchand, P.-A., D’Hollander, W., Thezenas, M.-L., Raes, M. J., & Silvestre, F. (2011) · Aquatic Toxicology · doi:10.1016/j.aquatox.2011.01.015 · Cited by 62

The association of carotid intima-media thickness with serum Level of perfluorinated chemicals and endothelium-platelet microparticles in adolescents and young adults

Lin, C., Chen, P., Lo, S., Torng, P., Sung, F., & Su, T. (2016) · Environment International · doi:10.1016/j.envint.2016.06.004 · Cited by 61

Exposure to persistent organic pollutants: impact on women’s health

Wahlang, B. (2018) · Reviews on Environmental Health · doi:10.1515/reveh-2018-0018 · Cited by 58

Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances affects leukocyte telomere length in female newborns

Liu, H., Chen, Q., Lei, L., Zhou, W., Huang, L., Zhang, J., & Chen, D. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2017.12.095 · Cited by 56

The relationship between perfluoroalkyl substances and hypertension: A systematic review and meta-analysis

Pan, K., Yu, J., Long, X., Yang, L., Huang, Z., & Yu, J. (2023) · Environmental Research · doi:10.1016/j.envres.2023.116362 · Cited by 56

Exposure to per- and polyfluoroalkyl substance and metabolic syndrome: A nationally representative cross-sectional study from NHANES, 2003–2018

Wu, M., Zhu, Z., Wan, R., & Xu, J. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.123615 · Cited by 53

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis

Hu, Z., Brooks, S. A., Dormoy, V., Hsu, C.-W., Hsu, H.-Y., Lin, L., Massfelder, T., Rathmell, W. K., Xia, M., Al‐Mulla, F., et al. (2015) · Carcinogenesis · doi:10.1093/carcin/bgv036 · Cited by 51

Association of Osteoarthritis with Perfluorooctanoate and Perfluorooctane Sulfonate in NHANES 2003–2008

Uhl, S. A., James-Todd, T. M., & Bell, M. L. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1205673 · Cited by 50

Association of Osteoarthritis With Serum Levels of the Environmental Contaminants Perfluorooctanoate and Perfluorooctane Sulfonate in a Large Appalachian Population

Innes, K. E., DUCATMAN, A. M., Luster, M. I., & Shankar, A. (2011) · American Journal of Epidemiology · doi:10.1093/aje/kwr107 · Cited by 50

Perfluoroalkyl substances in early pregnancy and risk of hypertensive disorders of pregnancy: A prospective cohort study

Huo, X., Huang, R., Gan, Y., Luo, K., Aimuzi, R., Nian, M., Ao, J., Feng, L., Tian, Y., Wang, W., et al. (2020) · Environment International · doi:10.1016/j.envint.2020.105656 · Cited by 50

Metabolomic, Lipidomic, Transcriptomic, and Metagenomic Analyses in Mice Exposed to PFOS and Fed Soluble and Insoluble Dietary Fibers

Deng, P., Durham, J., Liu, J., Zhang, X., Wang, C., Li, D., Gwag, T., Ma, M., & Hennig, B. (2022) · Environmental Health Perspectives · doi:10.1289/ehp11360 · Cited by 49

PFOS prenatal exposure induce mitochondrial injury and gene expression change in hearts of weaned SD rats

Xia, W., Wan, Y., Li, Y., Zeng, H., Lv, Z., Li, G., Wei, Z., & Xu, S. (2011) · Toxicology · doi:10.1016/j.tox.2011.01.011 · Cited by 46

Association of increased risk of cardiovascular diseases with higher levels of perfluoroalkylated substances in the serum of adults

Feng, X., Long, G., Zeng, G., Zhang, Q., Song, B., & Wu, K. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-22021-z · Cited by 45

Proteomic and histopathological response in the gills of Poecilia reticulata exposed to glyphosate-based herbicide

Rocha, T. L., dos Santos, A. P. R., Yamada, A. T., Soares, C. M. D. A., Borges, C. L., Bailão, A. M., & de Sabóia‐Morais, S. M. T. (2015) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2015.04.016 · Cited by 44

PFOS Modulates Interactive Epigenetic Regulation in First-Trimester Human Trophoblast Cell Line HTR-8/SVneo

Sonkar, R., Kay, M., & Choudhury, M. (2019) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.9b00198 · Cited by 44

Regulation of Corticosterone Secretion Is Modified by PFOS Exposure at Different Levels of the Hypothalamic-Pituitary-Adrenal axis in Adult Male Rats

Pereiro, N., Moyano, R., Blanco, A., & Lafuente, A. (2014) · Toxicology Letters · doi:10.1016/j.toxlet.2014.01.003 · Cited by 42

Co-exposure to PCB126 and PFOS increases biomarkers associated with cardiovascular disease risk and liver injury in mice

Deng, P., Wang, C., Wahlang, B., Sexton, T. R., Morris, A. J., & Hennig, B. (2020) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2020.115301 · Cited by 42

Nephrotoxicity of perfluorooctane sulfonate (PFOS)—effect on transcription and epigenetic factors

Wen, Y., Rashid, F., Fazal, Z., Singh, R., Spinella, M. J., & Irudayaraj, J. (2022) · Current Zoology · doi:10.1093/eep/dvac010 · Cited by 45

Proteomic Analysis of Cellular Response Induced by Multi-Walled Carbon Nanotubes Exposure in A549 Cells

Ju, L., Zhang, G., Zhang, X., Jia, Z., Gao, X., Jiang, Y., Yan, C., Duerksen-Hughes, P. J., Chen, F. F., Li, H., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0084974 · Cited by 42

Per- and polyfluoroalkyl substances and blood pressure in pre-diabetic adults—cross-sectional and longitudinal analyses of the diabetes prevention program outcomes study

Lin, P. D., Cárdenas, A., Hauser, R. B., Gold, D. R., Kleinman, K., Hivert, M., Calafat, A. M., Webster, T. F., Horton, E. S., & Oken, E. (2020) · Environment International · doi:10.1016/j.envint.2020.105573 · Cited by 44

Perfluorooctane sulfonate promotes atherosclerosis by modulating M1 polarization of macrophages through the NF-κB pathway

Wang, D., Tan, Z., Yang, J., Li, L., Li, H., Zhang, H., Liu, H., Liu, Y., Wang, L., Li, Q., et al. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.114384 · Cited by 41

Environmental Toxins and Oxidative Stress: The Link to Cardiovascular Diseases

Sule, R. O., Rivera, G. D. T., Vaidya, T., Gartrell, E., & Gomes, A. V. (2025) · Antioxidants · doi:10.3390/antiox14050604 · Cited by 41

Evaluation of cellular response to perfluorooctane sulfonate in human umbilical vein endothelial cells

Liao, Y., Wang, J., Huang, Q., Fang, C., Kiyama, R., Shen, H., & Dong, S. (2012) · Toxicology in Vitro · doi:10.1016/j.tiv.2012.01.011 · Cited by 43

The presence of MWCNTs reduces developmental toxicity of PFOS in early life stage of zebrafish

Wang, S., Zhuang, C., Du, J., Wu, C., & You, H. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2016.12.055 · Cited by 41

Per- and Polyfluoroalkyl Substance and Cardio Metabolic Markers in Firefighters

Khalil, N., DUCATMAN, A. M., Sinari, S. A., Billheimer, D. D., Hu, C., Littau, S. R., & Burgess, J. L. (2020) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0000000000002062 · Cited by 43

Three-year field study on the temporal response of soil microbial communities and functions to PFOA exposure

Huang, H. S., Lyu, X., Xiao, F., Fu, J., Xu, H., Wu, J., & Sun, Y. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.135008 · Cited by 41

ROS‐Triggered Autophagy Is Involved in PFOS‐Induced Apoptosis of Human Embryo Liver L‐02 Cells

Zeng, H., Zhu, B., Wang, Y.-Q., & He, Q. (2021) · BioMed Research International · doi:10.1155/2021/6625952 · Cited by 41

Early-life exposure to PCBs and PFAS exerts negative effects on the developing central nervous system

Peixoto-Rodrigues, M. C., Monteiro-Neto, J. R., Téglás, T., Toborek, M. J., Quinete, N., Hauser‐Davis, R. A., & Adesse, D. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.136832 · Cited by 39

The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

Engström, W., Darbre, P. D., Eriksson, S., Gulliver, L., Hultman, T., Karamouzis, M. V., Klaunig, J. E., Mehta, R., Moorwood, K., Sanderson, J. T., et al. (2015) · Carcinogenesis · doi:10.1093/carcin/bgv030 · Cited by 40

Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled carbon nanotubes on human small airway epithelial cells

Mihalchik, A. L., Ding, W., Porter, D. W., McLoughlin, C. E., Schwegler‐Berry, D., Sisler, J. D., Stefaniak, A. B., Snyder‐Talkington, B. N., Cruz‐Silva, R., Terrones, M., et al. (2015) · Toxicology · doi:10.1016/j.tox.2015.03.008 · Cited by 37

No association between perfluoroalkyl chemicals and hypertension in children

Geiger, S. D., Shankar, A., & Xiao, J. (2014) · Integrated Blood Pressure Control · doi:10.2147/ibpc.s47660 · Cited by 39

Quantitative detection of trace perfluorinated compounds in environmental water samples by Matrix-assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry with 1,8-bis(tetramethylguanidino)-naphthalene as matrix

Cao, D., Wang, Z., Han, C., Cui, L., Hu, M., Wu, J., Liu, Y., Cai, Y., Wang, H., & Kang, Y. (2011) · Talanta · doi:10.1016/j.talanta.2011.03.062 · Cited by 38

Per- and polyfluoroalkyl substances and calcifications of the coronary and aortic arteries in adults with prediabetes: Results from the diabetes prevention program outcomes study

Osorio-Yáñez, C., Sánchez-Guerra, M., Cárdenas, A., Lin, P. D., Hauser, R. B., Gold, D. R., Kleinman, K., Hivert, M., Fleisch, A. F., Calafat, A. M., et al. (2021) · Environment International · doi:10.1016/j.envint.2021.106446 · Cited by 36

Association between perfluoroalkyl substances exposure and the prevalence of nonalcoholic fatty liver disease in the different sexes: a study from the National Health and Nutrition Examination Survey 2005–2018

Limei, E., Zhang, S., & Jiang, X. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-25258-4 · Cited by 37

Possible role of serotonin and neuropeptide Y on the disruption of the reproductive axis activity by perfluorooctane sulfonate

López-Doval, S., Salgado, R., Fernández‐Pérez, B., & Lafuente, A. (2015) · Toxicology Letters · doi:10.1016/j.toxlet.2015.01.012 · Cited by 32

Mitochondrial activity and steroid secretion in mouse ovarian granulosa cells are suppressed by a PFAS mixture

Tatarczuch, A., Gogola-Mruk, J., Kotarska, K., Polański, Z., & Ptak, A. (2025) · Toxicology · doi:10.1016/j.tox.2025.154083 · Cited by 31

Human iPSC-derived endothelial cell sprouting assay in synthetic hydrogel arrays

Belair, D. G., Schwartz, M. P., Knudsen, T. B., & Murphy, W. L. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.05.020 · Cited by 31

Perfluoroctanoic acid (PFOA) enhances NOTCH-signaling in an angiogenesis model of placental trophoblast cells

Poteser, M., Hutter, H., Moshammer, H. M., & Weitensfelder, L. (2020) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2020.113566 · Cited by 32

Understanding the Impact of Perfluorinated Compounds on Cardiovascular Diseases and Their Risk Factors: A Meta-Analysis Study

Soheimi, S. S. A., Rahman, A. A., Latip, N. A., Ibrahim, E., & Kadir, S. H. S. A. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18168345 · Cited by 31

Perfluorooctane sulfonic acid (PFOS) inhibits vessel formation in a human 3D co-culture angiogenesis model (NCFs/HUVECs).

Forsthuber, M., Widhalm, R., Granitzer, S., Kaiser, A.-M., Moshammer, H., Hengstschläger, M., Dolznig, H., & Gundacker, C. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.118543 · Cited by 28

Association of Combined Per- and Polyfluoroalkyl Substances and Metals with Chronic Kidney Disease

Haruna, I., & Obeng-Gyasi, E. (2024) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph21040468 · Cited by 30

The ligand-docking approach explores the binding affinity of PFOS and PFOA for major endogenous antioxidants: A potential mechanism to fuel oxidative stress

Rajak, P., & Ganguly, A. (2023) · Sustainable Chemistry for the Environment · doi:10.1016/j.scenv.2023.100047 · Cited by 30

In vitro toxicity of perfluorooctane sulfonate on rat liver hepatocytes: probability of distructive binding to CYP 2E1 and involvement of cellular proteolysis

Khansari, M. R., Yousefsani, B. S., Kobarfard, F., Faizi, M., & Pourahmad, J. (2017) · Environmental Science and Pollution Research · doi:10.1007/s11356-017-9908-2 · Cited by 28

Associations of serum PFOA and PFOS levels with incident hypertension risk and change of blood pressure levels

Zhang, Z., Wang, F., Zhang, Y., Yao, J., Bi, J., He, J., Zhang, S., Wei, Y., Guo, H., Zhang, X., et al. (2022) · Environmental Research · doi:10.1016/j.envres.2022.113293 · Cited by 28

Epigenetic Consequences of In Utero PFAS Exposure: Implications for Development and Long-Term Health

Abdulkadir, A., Kandel, S., Lewis, N., D’Auvergne, O., Rosby, R., & Hossain, E. (2025) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph22060917 · Cited by 29

PFOS and PCB 153 have direct adverse effects on neonatal testis modeled using a coculture of primary gonocyte and sertoli cells

Zhang, J., Liang, J., Zhu, H., Li, C., & Wu, Q. (2011) · Environmental Toxicology · doi:10.1002/tox.20723 · Cited by 27

PFOS and F–53B disrupted inner cell mass development in mouse preimplantation embryo

Qiu, Y., Gao, M., Cao, T., Wang, J., Luo, M., Liu, S., Zeng, X., & Huang, J. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.140948 · Cited by 26

Perfluorodecanoic acid (PFDA) increases oxidative stress through inhibition of mitochondrial β-oxidation

Widhalm, R., Granitzer, S., Natha, B., Zoboli, O., Derx, J., Zeisler, H., Salzer, H. R., Weiss, S., Schmitner, N., Kimmel, R. A., et al. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.125595 · Cited by 29

The association of perfluoroalkyl substances (PFAS) exposure and kidney function in Korean adolescents using data from Korean National Environmental Health Survey (KoNEHS) cycle 4 (2018–2020): a cross-sectional study

Yun, J., Jang, E.-C., Kwon, S.-C., Min, Y., & Lee, Y.-J. (2023) · Annals of Occupational and Environmental Medicine · doi:10.35371/aoem.2023.35.e5 · Cited by 27

Exposure characteristics of legacy and novel per- and polyfluoroalkyl substances in blood and association with hypertension among low-exposure population

Lin, N., Zhang, Y., Su, S., Feng, Y., Wang, B., & Li, Z. (2023) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2023.132185 · Cited by 26

Serum perfluoroalkyl substances in children exposed to the world trade center disaster

Trasande, L., Koshy, T. T., Gilbert, J., Burdine, L. K., Attinà, T. M., Ghassabian, A., Honda, M., Marmor, M. F., Chu, D. B., Han, X., et al. (2017) · Environmental Research · doi:10.1016/j.envres.2017.01.008 · Cited by 26

Per- and Polyfluoroalkyl Substances (PFAS) Enhance Cholesterol Accumulation and Dysregulate Inflammatory Responses in Macrophages

Connolly, J. C., Ishihara, Y., Sawaya, E., Whitfield, V., Garrity, N., Sohata, R., Tsymbal, M., Lundberg, A., Merrill, M. A. L., DeWitt, J. C., et al. (2025) · Cardiovascular Toxicology · doi:10.1007/s12012-025-10048-w · Cited by 27

NLRP3 inflammasome-mediated endothelial cells pyroptosis is involved in decabromodiphenyl ethane-induced vascular endothelial injury

Zheng, D., Shi, Z., Yang, M. G., Liang, B., Zhou, X., Li, J., & Sun, Z. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.128867 · Cited by 25

Proton sponge-functionalized silica as high performance adsorbents for solid-phase extraction of trace perfluoroalkyl sulfonates in the environmental water samples and their direct analysis by MALDI-TOF-MS

Cao, D., Hu, M., Han, C., Yu, J., Cui, L., Liu, Y., Wang, H., Cai, Y., Kang, Y., & Zhou, Y. (2012) · The Analyst · doi:10.1039/c2an16190g · Cited by 26

Evaluation of cellular response to perfluorooctane sulfonate in human umbilical vein endothelial cells

Liao, Y., Wang, J., Huang, Q., Fang, C., Kiyama, R., Shen, H., & Dong, S. (2012) · Toxicology in Vitro · doi:10.1016/j.tiv.2012.01.011 · Cited by 43

Ferroptosis and Oxidative Stress Are Implicated Perfluorooctane Sulfonate‐Elicited Cytotoxicity to Human Umbilical Vein Endothelial Cells

Cui, J., Yan, S., Li, W., Haoyan, M., Pan, Q., Ren, S., & Guo, L. (2026) · Journal of Applied Toxicology · doi:10.1002/jat.70443

Perfluorooctane Sulfonate Induces Dysfunction of Human Umbilical Vein Endothelial Cells via Ferroptosis Pathway

Cui, J., Wang, P., Yan, S., Liang, Y., Liu, D., & Ren, S. (2022) · Toxics · doi:10.3390/toxics10090503 · Cited by 24

Perfluorooctane sulfonic acid: a possible risk factor of endothelial dysfunction based on in silico and in vitro studies

Vajeethaveesin, N., Kanitwithayanun, J., Suriyo, T., Chujan, S., & Satayavivad, J. (2025) · Archives of Toxicology · doi:10.1007/s00204-025-04047-7 · Cited by 8

P09-18 The effect of perfluorooctanoic acid and perfluorobutanoic acid on selected cytotoxic and oxidative parameters in human peripheral blood mononuclear cells

Kaczmarska, I., Mokra, K., & Michałowicz, J. (2025) · Toxicology Letters · doi:10.1016/j.toxlet.2025.07.304