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Integrated hypothesis of dental caries and periodontal diseases

Nyvad, Bente, Takahashi, Nobuhiro·2020·Journal of Oral Microbiology
DOI 10.1080/20002297.2019.1710953PMC PMC6968559
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Figure 1. Illustration of three theoretical pH response patterns in the integrated hypothesis of dental caries and periodontal diseases. The green curve illustrates pH fluctuations of the microbiota at the dynamic stability stage associated with clinical health, at which pH fluctuations are balanced over time due to infrequent nutrient exposures. The red and blue curves show pH fluctuations of the microbiota at subgingival and supragingival sites in response to increasing exposure microbial nutrients, respectively. When GCF/inflammatory nutrients are intense and prolonged, pH of the microbiota may drift from the dynamic stability stage into proteolytic/amino-acid degrading and inflammatory stages associated with gingivitis and periodontitis (red curve), whereas intense and prolonged increases in exposure to dietary carbohydrates promotes a drift of pH into acidogenic and aciduric stages associated with caries (blue curve). For further details, see text
Figure 1. Illustration of three theoretical pH response patterns in the integrated hypothesis of dental caries and periodontal diseases. The green curve illustrates pH fluctuations of the microbiota at the dynamic stability stage associated with clinical health, at which pH fluctuations are balanced over time due to infrequent nutrient exposures. The red and blue curves show pH fluctuations of the microbiota at subgingival and supragingival sites in response to increasing exposure microbial nutrients, respectively. When GCF/inflammatory nutrients are intense and prolonged, pH of the microbiota may drift from the dynamic stability stage into proteolytic/amino-acid degrading and inflammatory stages associated with gingivitis and periodontitis (red curve), whereas intense and prolonged increases in exposure to dietary carbohydrates promotes a drift of pH into acidogenic and aciduric stages associated with caries (blue curve). For further details, see textCC BY · PubMed Central
Figure 2. Overview of intrinsic and bacterial metabolic resilience factors operating at the dynamic stability stage. Bacterial metabolic resilience comprises two categories: bi-directional pH metabolic regulation and autonomic metabolic repression. Resilience factor marked in red = acidification factor, which is more active under alkaline than under acidic conditions. Resilience factors marked in blue = acid-neutralization/alkalization factors, some of which are more active under acidic than under alkaline conditions or active at a wide range of pH. Some bacterial metabolites, such as NH3 and sulfur compounds are inflammatory factors. For detailed description, see text
Figure 2. Overview of intrinsic and bacterial metabolic resilience factors operating at the dynamic stability stage. Bacterial metabolic resilience comprises two categories: bi-directional pH metabolic regulation and autonomic metabolic repression. Resilience factor marked in red = acidification factor, which is more active under alkaline than under acidic conditions. Resilience factors marked in blue = acid-neutralization/alkalization factors, some of which are more active under acidic than under alkaline conditions or active at a wide range of pH. Some bacterial metabolites, such as NH3 and sulfur compounds are inflammatory factors. For detailed description, see textCC BY · PubMed Central

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Research works printed but not linked: 94

  1. 10.1177/00220345600390052701 · DOI
  2. Theilade E, 1976, Oral Sci Rev, 9, 23
  3. Loesche WJ, 1976, Oral Sci Rev, 9, 65
  4. 10.1902/jop.1977.48.9.497 · DOI
  5. 10.1177/00220345790580120905 · DOI
  6. 10.1111/j.1600-051X.1986.tb01425.x · DOI
  7. 10.1177/08959374940080022001 · DOI · Paper page
  8. 10.1038/ismej.2012.174 · DOI
  9. 10.1111/j.1600-0757.2012.00450.x · DOI
  10. 10.1111/prd.12169 · DOI
  11. 10.1111/omi.12065 · DOI
  12. 10.1016/j.ics.2005.06.071 · DOI
  13. 10.1159/000159604 · DOI
  14. 10.1177/0022034510379602 · DOI
  15. 10.1159/000447309 · DOI
  16. 10.1146/annurev.ecolsys.35.021103.105711 · DOI · Paper page
  17. 10.1159/000488948 · DOI
  18. Diaz PI, 2016, J Calif Dent Assoc, 44, 421, 10.1080/19424396.2016.12221035 · DOI
  19. 10.1111/jcpe.12679 · DOI
  20. 10.1177/0022034517742139 · DOI · Paper page
  21. 10.1111/jcpe.12671 · DOI
  22. 10.3389/fcimb.2014.00092 · DOI
  23. 10.1177/00220345920710010401 · DOI
  24. 10.1159/000016628 · DOI
  25. 10.1177/00220345910700120601 · DOI
  26. 10.1177/00220345000790021201 · DOI
  27. 10.1111/prd.12107 · DOI
  28. 10.1111/j.1399-302X.1997.tb00733.x · DOI
  29. 10.1034/j.1399-302X.2003.00054.x · DOI
  30. 10.1902/jop.2008.080173 · DOI
  31. 10.1016/0003-9969(91)90091-8 · DOI · Paper page
  32. 10.1111/j.1600-0757.1994.tb00019.x · DOI
  33. 10.1111/j.1574-6976.2008.00150.x · DOI
  34. Lang NP, 2018, J Periodontol, 89, S9, 10.1902/jop.2017.170249 · DOI
  35. 10.1111/j.1753-4887.2012.00489.x · DOI
  36. 10.1007/s10021-001-0045-9 · DOI
  37. 10.5751/ES-03610-150420 · DOI
  38. 10.1146/annurev.es.04.110173.000245 · DOI · Paper page
  39. 10.1007/s100219900002 · DOI · Paper page
  40. 10.1126/science.277.5325.500 · DOI
  41. 10.4319/lo.2004.49.4_part_2.1269 · DOI
  42. 10.1890/1540-9295(2003)001[0488:RDECAR]2.0.CO;2 · DOI · Paper page
  43. 10.1177/00220345870660S103 · DOI
  44. Edgar M, 1996, Saliva and Oral Health, 81
  45. 10.1177/154405910608500410 · DOI
  46. 10.1159/000070450 · DOI
  47. 10.1111/j.1600-0765.1971.tb00615.x · DOI
  48. 10.1111/j.1574-6968.2000.tb09393.x · DOI · Paper page
  49. 10.1016/0003-9969(74)90177-0 · DOI
  50. 10.1128/IAI.64.2.585-592.1996 · DOI
  51. 10.1177/10454411970080030301 · DOI
  52. 10.1177/154405910808700108 · DOI
  53. 10.1016/S0003-9969(08)70003-7 · DOI
  54. 10.1099/jmm.0.46118-0 · DOI
  55. 10.1128/AEM.00606-14 · DOI
  56. Yamamoto Y, 2017, Oral Health Prev Dent, 15, 153
  57. 10.1128/IAI.40.1.70-80.1983 · DOI
  58. Carlsson J, 1986, Textbook of cariology, 74
  59. 10.1016/0003-9969(74)90267-2 · DOI
  60. 10.1371/journal.pone.0071227 · DOI
  61. 10.1111/j.1600-0765.1980.tb00269.x · DOI
  62. 10.1128/JCM.43.11.5721-5732.2005 · DOI · Paper page
  63. 10.1159/000446249 · DOI · Paper page
  64. 10.1016/j.jdent.2016.03.002 · DOI
  65. 10.1007/s00784-013-0990-7 · DOI
  66. 10.1038/d41586-019-03595-0 · DOI
  67. 10.3402/jom.v7.27429 · DOI
  68. 10.1038/srep22164 · DOI · Paper page
  69. Nyvad B, Caries Res
  70. 10.1177/2380084417723625 · DOI
  71. 10.1111/jcpe.12117 · DOI
  72. 10.1111/j.1600-0757.2004.03795.x · DOI · Paper page
  73. Nyvad B, 2015, Dental Caries: the Disease and Its Clinical management, 277
  74. 10.1177/0022034515590377 · DOI · Paper page
  75. 10.1002/146558.CD006540.pub2 · DOI
  76. 10.1159/000489571 · DOI
  77. 10.1016/B978-0-7236-0368-9.50008-2 · DOI
  78. Yudkin J, 1972, Pure, white and deadly: the problem of sugar
  79. 10.1111/jcpe.13094 · DOI
  80. 10.3945/ajcn.114.089656 · DOI · Paper page
  81. 10.1177/0022034517745326 · DOI
  82. 10.2337/diabetes.54.6.1615 · DOI · Paper page
  83. 10.1002/iub.1610 · DOI
  84. 10.1111/jcpe.12803 · DOI
  85. Taylor JJ, 2013, J Clin Periodontol, 40, S113, 10.1111/jcpe.12059 · DOI
  86. 10.1007/s40496-016-0099-6 · DOI
  87. 10.1080/20002297.2017.1332710 · DOI
  88. 10.1111/j.1600-051X.1996.tb01804.x · DOI
  89. Lal S, 2007, Pediatr Dent, 29, 426
  90. 10.1111/j.1600-051X.2005.00682.x · DOI
  91. 10.2337/dc11-2453 · DOI
  92. 10.1111/j.1600-051X.1995.tb00125.x · DOI
  93. 10.1111/j.1600-0528.1997.tb00894.x · DOI · Paper page
  94. 10.1111/prd.12110 · DOI

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Metadata

Authors
Nyvad, B., & Takahashi, N.
Affiliations
  • Section of Dental Pathology, Operative Dentistry and Endodontics, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark
  • Division of Oral Ecology and Biochemistry, Department of Oral Biology, Tohoku University Graduate School of Dentistry, Sendai, Japan
ORCID
Venue
Journal of Oral Microbiology
Publisher
Informa UK Limited
Published
2020-01-01
Volume
12
Issue
1
Pages
1710953
ISSN
2000-2297
DOI
10.1080/20002297.2019.1710953
PMC
PMC6968559
Cited by
194
References
16
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (unspecified, 311 d)
Funders
Yngve Ericsson Research Prize

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