The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
The evolution of metazoan extracellular matrix
Open accessAbstract
The modular domain structure of extracellular matrix (ECM) proteins and their genes has allowed extensive exon/domain shuffling during evolution to generate hundreds of ECM proteins. Many of these arose early during metazoan evolution and have been highly conserved ever since. Others have undergone duplication and divergence during evolution, and novel combinations of domains have evolved to generate new ECM proteins, particularly in the vertebrate lineage. The recent sequencing of several genomes has revealed many details of this conservation and evolution of ECM proteins to serve diverse functions in metazoa.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Extracellular Matrix: Not Just Pretty Fibrils
Hynes, R. O. (2009) · Science · doi:10.1126/science.1176009 · Cited by 3,527
Self-citationThe Draft Genome of Ciona intestinalis : Insights into Chordate and Vertebrate Origins
Dehal, P., Satou, Y., Campbell, R. K., Chapman, J., Degnan, B., De Tomaso, A., Davidson, B., Di Gregorio, A., Gelpke, M., Goodstein, D. M., et al. (2002) · Science · doi:10.1126/science.1080049 · Cited by 1,641 · cited 2×
“ECM proteins are typically composed of multiple protein domains, and their gene structures were some of the first recognized to have arisen by exon shuffling (Engel, 1996; Patthy, 1999; Hohenester and Engel, 2002).”
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization
Putnam, N. H., Srivastava, M., Hellsten, U., Dirks, B., Chapman, J., Salamov, A., Terry, A., Shapiro, H., Lindquist, E., Kapitonov, V. V., et al. (2007) · Science · doi:10.1126/science.1139158 · Cited by 1,555
Naba, A., Clauser, K. R., Hoersch, S., Liu, H., Carr, S. A., & Hynes, R. O. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m111.014647 · Cited by 1,354
Self-citationOverview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions
Hynes, R. O., & Naba, A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004903 · Cited by 1,349
Self-citationThe genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
King, N., Westbrook, M. J., Young, S. L., Kuo, A., Abedin, M., Chapman, J., Fairclough, S., Hellsten, U., Isogai, Y., Letunic, I., et al. (2008) · Nature · doi:10.1038/nature06617 · Cited by 1,139
The Amphimedon queenslandica genome and the evolution of animal complexity
Srivastava, M., Simakov, O., Chapman, J., Fahey, B., Gauthier, M. E. A., Mitros, T., Richards, G. S., Conaco, C., Dacre, M., Hellsten, U., et al. (2010) · Nature · doi:10.1038/nature09201 · Cited by 1,049
Philippe, H., Lartillot, N., & Brinkmann, H. (2005) · Molecular Biology and Evolution · doi:10.1093/molbev/msi111 · Cited by 551
Extracellular Matrix: Functions in the Nervous System
Barros, C. S., Franco, S. J., & Muller, U. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005108 · Cited by 506
Evolution of Key Cell Signaling and Adhesion Protein Families Predates Animal Origins
King, N., Hittinger, C. T., & Carroll, S. B. (2003) · Science · doi:10.1126/science.1083853 · Cited by 424
The Evolution of Extracellular Matrix
Özbek, S., Balasubramanian, P. G., Chiquet-Ehrismann, R., Tucker, R. P., & Adams, J. C. (2010) · Molecular Biology of the Cell · doi:10.1091/mbc.e10-03-0251 · Cited by 347
Schierwater, B., Eitel, M., Jakob, W., Osigus, H.-J., Hadrys, H., Dellaporta, S. L., Kolokotronis, S.-O., & DeSalle, R. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000020 · Cited by 260
A simple plan-Cnidarians and the origins of developmental mechanisms
Ball, E. E., Hayward, D. C., Saint, R., & Miller, D. J. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1402 · Cited by 123
The Radiata and the evolutionary origins of the bilaterian body plan
Martindale, M. Q., Finnerty, J. R., & Henry, J. Q. (2002) · Molecular Phylogenetics and Evolution · doi:10.1016/s1055-7903(02)00208-7 · Cited by 110
Research works printed but not linked: 40
- Adams, 2011, The thrombospondins, Cold Spring Harb. Perspect. Biol., 3, a009712, 10.1101/cshperspect.a009712 · DOI · Paper page
- Aouacheria, 2006, Insights into early extracellular matrix evolution: spongin short chain collagen-related proteins are homologous to basement membrane type IV collagens and form a novel family widely distributed in invertebrates, Mol. Biol. Evol., 23, 2288, 10.1093/molbev/msl100 · DOI
- Bentley, 2010, The evolution of thrombospondins and their ligand-binding activities, Mol. Biol. Evol., 27, 2187, 10.1093/molbev/msq107 · DOI
- Bergmeier, 2012, Extracellular matrix proteins in hemostasis and thrombosis, Cold Spring Harb. Perspect. Biol., 4, a005132, 10.1101/cshperspect.a005132 · DOI
- Boute, 1996, Type IV collagen in sponges, the missing link in basement membrane ubiquity, Biol. Cell., 88, 37, 10.1016/S0248-4900(97)86829-3 · DOI
- Chapman, 2010, The dynamic genome of Hydra, Nature., 464, 592, 10.1038/nature08830 · DOI · Paper page
- Chiquet-Ehrismann, 2011, Tenascins and the importance of adhesion modulation, Cold Spring Harb. Perspect. Biol., 3, a004960, 10.1101/cshperspect.a004960 · DOI · Paper page
- Couchman, 2010, Transmembrane signaling proteoglycans, Annu. Rev. Cell Dev. Biol., 26, 89, 10.1146/annurev-cellbio-100109-104126 · DOI · Paper page
- Engel, 1996, Domain organizations of modular extracellular matrix proteins and their evolution, Matrix Biol., 15, 295, 10.1016/S0945-053X(96)90130-4 · DOI
- Ewan, 2005, The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family, BMC Evol. Biol., 5, 31, 10.1186/1471-2148-5-31 · DOI
- Exposito, 2008, Demosponge and sea anemone fibrillar collagen diversity reveals the early emergence of A/C clades and the maintenance of the modular structure of type V/XI collagens from sponge to human, J. Biol. Chem., 283, 28226, 10.1074/jbc.M804573200 · DOI
- Exposito, 2010, The fibrillar collagen family, Int. J. Mol. Sci., 11, 407, 10.3390/ijms11020407 · DOI · Paper page
- Fahey, 2010, Origin of animal epithelia: insights from the sponge genome, Evol. Dev., 12, 601, 10.1111/j.1525-142X.2010.00445.x · DOI · Paper page
- Gazave, 2010, Molecular phylogeny restores the supra-generic subdivision of homoscleromorph sponges (Porifera, Homoscleromorpha), PLoS ONE., 5, e14290, 10.1371/journal.pone.0014290 · DOI
- Heino, 2009, Evolution of collagen-based adhesion systems, Int. J. Biochem. Cell Biol., 41, 341, 10.1016/j.biocel.2008.08.021 · DOI
- Hohenester, 2002, Domain structure and organisation in extracellular matrix proteins, Matrix Biol., 21, 115, 10.1016/S0945-053X(01)00191-3 · DOI
- Huhtala, 2005, Integrin evolution: insights from ascidian and teleost fish genomes, Matrix Biol., 24, 83, 10.1016/j.matbio.2005.01.003 · DOI
- Hutter, 2000, Conservation and novelty in the evolution of cell adhesion and extracellular matrix genes, Science., 287, 989, 10.1126/science.287.5455.989 · DOI · Paper page
- Huxley-Jones, 2007, On the origins of the extracellular matrix in vertebrates, Matrix Biol., 26, 2, 10.1016/j.matbio.2006.09.008 · DOI
- Hynes, 2000, The evolution of cell adhesion, J. Cell Biol., 150, F89, 10.1083/jcb.150.2.F89 · DOI · Paper page
- Knack, 2008, Unexpected diversity of cnidarian integrins: expression during coral gastrulation, BMC Evol. Biol., 8, 136, 10.1186/1471-2148-8-136 · DOI
- Merline, 2009, The matricellular functions of small leucine-rich proteoglycans (SLRPs), J Cell Commun Signal., 3, 323, 10.1007/s12079-009-0066-2 · DOI
- Myllyharju, 2004, Collagens, modifying enzymes and their mutations in humans, flies and worms, Trends Genet., 20, 33, 10.1016/j.tig.2003.11.004 · DOI · Paper page
- Patthy, 1999, Genome evolution and the evolution of exon-shuffling—a review, Gene., 238, 103, 10.1016/S0378-1119(99)00228-0 · DOI · Paper page
- Philippe, 2009, Phylogenomics revives traditional views on deep animal relationships, Curr. Biol., 19, 706, 10.1016/j.cub.2009.02.052 · DOI · Paper page
- Pick, 2010, Improved phylogenomic taxon sampling noticeably affects nonbilaterian relationships, Mol. Biol. Evol., 27, 1983, 10.1093/molbev/msq089 · DOI · Paper page
- Putnam, 2008, The amphioxus genome and the evolution of the chordate karyotype, Nature., 453, 1064, 10.1038/nature06967 · DOI · Paper page
- Ricard-Blum, 2011, The collagen family, Cold Spring Harb. Perspect. Biol., 3, a004978, 10.1101/cshperspect.a004978 · DOI · Paper page
- Robertson, 2011, TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs, Biochem. J., 433, 263, 10.1042/BJ20101320 · DOI
- Sadler, 2009, von Willebrand factor assembly and secretion, J. Thromb. Haemost., 7, 24, 10.1111/j.1538-7836.2009.03375.x · DOI
- Schaefer, 2010, Proteoglycans: from structural compounds to signaling molecules, Cell Tissue Res., 339, 237, 10.1007/s00441-009-0821-y · DOI · Paper page
- Sebé-Pedrós, 2010, Ancient origin of the integrin-mediated adhesion and signaling machinery, Proc. Natl. Acad. Sci. USA., 107, 10142, 10.1073/pnas.1002257107 · DOI · Paper page
- Shalchian-Tabrizi, 2008, Multigene phylogeny of choanozoa and the origin of animals, PLoS ONE., 3, e2098, 10.1371/journal.pone.0002098 · DOI · Paper page
- Srivastava, 2008, The Trichoplax genome and the nature of placozoans, Nature., 454, 955, 10.1038/nature07191 · DOI · Paper page
- Tucker, 2009, Evidence for the evolution of tenascin and fibronectin early in the chordate lineage, Int. J. Biochem. Cell Biol., 41, 424, 10.1016/j.biocel.2008.08.003 · DOI
- Wada, 2006, Molecular evolution of fibrillar collagen in chordates, with implications for the evolution of vertebrate skeletons and chordate phylogeny, Evol. Dev., 8, 370, 10.1111/j.1525-142X.2006.00109.x · DOI
- Whittaker, 2002, Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere, Mol. Biol. Cell., 13, 3369, 10.1091/mbc.E02-05-0259 · DOI · Paper page
- Whittaker, 2006, The echinoderm adhesome, Dev. Biol., 300, 252, 10.1016/j.ydbio.2006.07.044 · DOI · Paper page
- Yurchenco, 2011, Basement membranes: cell scaffoldings and signaling platforms, Cold Spring Harb. Perspect. Biol., 3, a004911, 10.1101/cshperspect.a004911 · DOI · Paper page
- Zhang, 2007, The collagens of hydra provide insight into the evolution of metazoan extracellular matrices, J. Biol. Chem., 282, 6792, 10.1074/jbc.M607528200 · DOI
Cited by
The extracellular matrix: tools and insights for the "omics" era
Naba, A., Clauser, K. R., Ding, H., Whittaker, C. A., Carr, S. A., & Hynes, R. O. (2016) · Matrix Biology · doi:10.1016/j.matbio.2015.06.003 · Cited by 1,037
Self-citationExtracellular matrix-based materials for regenerative medicine
Hussey, G. S., Dziki, J. L., & Badylak, S. F. (2018) · Nature Reviews Materials · doi:10.1038/s41578-018-0023-x · Cited by 844
TGF-β1 Signaling and Tissue Fibrosis
Kim, K. K., Sheppard, D., & Chapman, H. A. (2018) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a022293 · Cited by 800
The myofibroblast matrix: implications for tissue repair and fibrosis
Klingberg, F., Hinz, B., & White, E. S. (2013) · The Journal of Pathology · doi:10.1002/path.4104 · Cited by 776
Cancer across the tree of life: cooperation and cheating in multicellularity
Aktipis, C. A., Boddy, A. M., Jansen, G., Hibner, U., Hochberg, M. E., Maley, C. C., & Wilkinson, G. S. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2014.0219 · Cited by 466
Metadata
- Authors
- Hynes, R. O.
- Venue
- Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2012-03-19
- Volume
- 196
- Issue
- 6
- Pages
- 671-679
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2136022210
- Cited by
- 273
- References
- 14
- FWCI
- 15.95
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
