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Optical properties of biological tissues: a review
Open accessAbstract
A review of reported tissue optical properties summarizes the wavelength-dependent behavior of scattering and absorption. Formulae are presented for generating the optical properties of a generic tissue with variable amounts of absorbing chromophores (blood, water, melanin, fat, yellow pigments) and a variable balance between small-scale scatterers and large-scale scatterers in the ultrastructures of cells and tissues.
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“For the scattering, the average number density (a) is 8.54 ± 1.4 and the average effective particle size (b) is 0.75 ± 0.24, for the relationship derived from the Mie model (Jacques 2013).”
From Validation of a novel wearable, wireless technology to estimate oxygen levels and lactate threshold power in the exercising muscle (2018) · cites this paper as Jacques 2013
Experimental — accuracy not yet measuredIn the citing paper
“In particular, obesity can lead to changes in skin thickness, blood flow, and oxygen saturation. This affects the optical properties of skin in addition to the distance light has to travel to reach a target vessel or vessels [48,59,60].”
From Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring (2021) · cites this paper as [48]
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Metadata
- Authors
- Jacques, S. L.
- Affiliations
- Oregon Health & Science University (US)
- Corresponding author
- Jacques, Steven L
- ORCID
- Jacques, Steven L
- Venue
- Physics in Medicine and Biology
- Publisher
- IOP Publishing
- Published
- 2013-05-10
- Volume
- 58
- Issue
- 11
- Pages
- R37-R61
- ISSN
- 0031-9155 (ISSN-L)
- 1361-6560
- OpenAlex
- W2097683070
- Cited by
- 4,008
- References
- 74
- Citations by year
- 2026: 350 · 2025: 346 · 2024: 313 · 2023: 332 · 2022: 323 · 2021: 362 · 2020: 363 · 2019: 383 · 2018: 320 · 2017: 299 · 2016: 272 · 2015: 217 · 2014: 107 · 2013: 15
- FWCI
- 28.94
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Physics in Medicine and Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
- Physical Sciences › Engineering › Biomedical Engineering › Optical Coherence Tomography Applications
- Keywords
- tissue optical properties, light scattering, optical absorption, chromophores, blood, melanin, fats, wavelength dependence, cell ultrastructure
- MeSH terms
- Animals, Biology, Humans, Anisotropy, Optical Phenomena
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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