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Cited by 384

The DOI matches its Crossref record; 200 of the 200 references it cites were found in a registry or an index.

AFM: a versatile tool in biophysics

Open access
Alessandrini, Andrea, Facci, Paolo·2005·Measurement Science and Technology

Abstract

Here we review the applications of atomic force microscopy to the study of samples of biological origin. Emphasis is given to provide the reader with information on the broad range of different biophysical applications that, to date, such a technique can deal with. After recalling briefly the operating principles of an atomic force microscope, the broad field of bio-imaging applications is faced (DNA, DNA–protein interaction, proteins, lipid membranes, cells); thereafter, the use of the atomic force microscope to measure forces is introduced and force mapping on living cells is discussed. This section is followed by the description of the use of force curves in assessing single-molecule inter- and intramolecular interactions. A paragraph on the perspectives of the technique in biophysical applications concludes the paper. We hope that this review can help the reader in appreciating how atomic force microscopy contributes to the current explosive growth of nanobiosciences, where biology, chemistry and physics merge.

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Crossref · 10.1088/0957-0233/16/6/r01

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Metadata

Authors
Alessandrini, A., & Facci, P.
Venue
Measurement Science and Technology
Published
2005-04-28
Volume
16
Issue
6
Pages
R65-R92
ISSN
  • 0957-0233 (ISSN-L)
  • 1361-6501
OpenAlex
W2097959420
Cited by
384
References
200
FWCI
11.07
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: AFM: a versatile tool in biophysics. https://app.cochat.ai/papers/10.1088/0957-0233/16/6/r01
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Alessandrini, A., & Facci, P. (2005). AFM: a versatile tool in biophysics. Measurement Science and Technology. https://doi.org/10.1088/0957-0233/16/6/r01

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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