Cited by 339Regulation of Appetite and ObesityDiet, Metabolism, and DiseaseMuscle metabolism and nutrition

The DOI matches its Crossref record; 37 of the 38 references it cites were found in a registry or an index.

Fat and carbohydrate overfeeding in humans: different effects on energy storage

Horton, TJ, Drougas, H, Brachey, A, Reed, GW, Peters, JC, Hill, JO·1995·The American Journal of Clinical Nutrition

Open this paper in CoChat — free account

Abstract

Both the amount and composition of food eaten influence body-weight regulation. The purpose of this study was to determine whether and by what mechanism excess dietary fat leads to greater fat accumulation than does excess dietary carbohydrate. We overfed isoenergetic amounts (50% above energy requirements) of fat and carbohydrate (for 14 d each) to nine lean and seven obese men. A whole-room calorimeter was used to measure energy expenditure and nutrient oxidation on days 0, 1, 7, and 14 of each overfeeding period. From energy and nutrient balances (intake-expenditure) we estimated the amount and composition of energy stored. Carbohydrate overfeeding produced progressive increases in carbohydrate oxidation and total energy expenditure resulting in 75-85% of excess energy being stored. Alternatively, fat overfeeding had minimal effects on fat oxidation and total energy expenditure, leading to storage of 90-95% of excess energy. Excess dietary fat leads to greater fat accumulation than does excess dietary carbohydrate, and the difference was greatest early in the overfeeding period.

Integrity signals

Registry

Crossref · 10.1093/ajcn/62.1.19

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

DENSITOMETRIC ANALYSIS OF BODY COMPOSITION: REVISION OF SOME QUANTITATIVE ASSUMPTIONS*
Brožek, J., Grande, F., Anderson, J. T., & Keys, A. B. (1963) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1963.tb17079.x · Cited by 2,263
Maximal oxygen intake and nomographic assessment of functional aerobic impairment in cardiovascular disease
Bruce, R. A., Kusumi, F., & Hosmer, D. W. (1973) · American Heart Journal · doi:10.1016/0002-8703(73)90502-4 · Cited by 2,057
The Response to Long-Term Overfeeding in Identical Twins
Bouchard, C., Tremblay, A., Després, J.-P., Nadeau, A., Lupien, P. J., Thériault, G., Dussault, J., Moorjani, S., Pinault, S., & Fournier, G. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005243222101 · Cited by 1,278
Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ
ZURLO, F., Lillioja, S., Puente, A. E.-D., Nyomba, B. L. G., Raz, I., Saad, M. F., Swinburn, B. A., Knowler, W. C., Bogardus, C., & Ravussin, É. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.5.e650 · Cited by 709
Assessment of Energy Expenditure and Fuel Utilization in Man
Jéquier, E., Acheson, K. J., & Schütz, Y. (1987) · Annual Review of Nutrition · doi:10.1146/annurev.nu.07.070187.001155 · Cited by 532
Dietary fat and serum lipids: an evaluation of the experimental data
Hegsted, D., Ausman, L., Johnson, J., & Dallal, G. (1993) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/57.6.875 · Cited by 515
Dietary fat and the regulation of energy intake in human subjects
Lissner, L., Levitsky, D. A., Strupp, B. J., Kalkwarf, H. J., & Roe, D. A. (1987) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/46.6.886 · Cited by 502
Techniques for Measuring Body Composition.
Forbes, G. B. (1962) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1962.02080030207026 · Cited by 500
Effects of dietary fat on postprandial substrate oxidation and on carbohydrate and fat balances.
Flatt, J. P., Ravussin, É., Acheson, K. J., & Jéquier, E. (1985) · Journal of Clinical Investigation · doi:10.1172/jci112054 · Cited by 412
Measurement of de novo hepatic lipogenesis in humans using stable isotopes.
Hellerstein, M. K., Christiansen, M., Kaempfer, S., Kletke, C., Wu, K. K., Reid, J., Mulligan, K. M., Hellerstein, N. S., & Shackleton, C. H. L. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115206 · Cited by 362

Show all 38 references

Research works printed but not linked: 1

Schwartz, 1993, Effect of oral fructose on lipolysis, fat oxidation, fractional and absolute de novo lipogenesis (DNL) using mass isotopomer distribution analysis (MIDA)., FASEB J, 7, A867

Sorted by citations

Items 101–200 of 339

Expression of Selenoprotein Genes Is Affected by Obesity of Pigs Fed a High-Fat Diet
Zhao, H. Y., Li, K., Tang, J., Zhou, J., Wang, K., Xia, X., & Lei, X. G. (2015) · Journal of Nutrition · doi:10.3945/jn.115.211318 · Cited by 69
Physical activity and energy requirements
Hill, J., Melby, C. L., Johnson, S., & Peters, J. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.5.1059s · Cited by 66
Self-citation
Effect of protein overfeeding on energy expenditure measured in a metabolic chamber
Bray, G. A., Redman, L. M., de Jonge, L., Covington, J., Rood, J., Brock, C., Mancuso, S., Martin, C. K., & Smith, S. R. (2015) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.091769 · Cited by 65
Resistance and aerobic exercise have similar effects on 24-h nutrient oxidation
MELANSON, E. L., SHARP, T. A., SEAGLE, H. M., DONAHOO, W. T., GRUNWALD, G. K., PETERS, J. C., HAMILTON, J. T., & HILL, J. O. (2002) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200211000-00016 · Cited by 65
Self-citation
Two weeks of overfeeding with candy, but not peanuts, increases insulin levels and body weight
Claesson, A.-L., Holm, G., Ernersson, Å., Lindström, T., & Nyström, F. H. (2009) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510902912754 · Cited by 64
Lack of findings for the association between obesity risk and usual sugar-sweetened beverage consumption in adults – A primary analysis of databases of CSFII-1989–1991, CSFII-1994–1998, NHANES III, and combined NHANES 1999–2002
Sun, S. Z., & Empie, M. W. (2007) · Food and Chemical Toxicology · doi:10.1016/j.fct.2007.02.012 · Cited by 64
Concept of fat balance in human obesity revisited with particular reference to de novo lipogenesis
Schutz, Y. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802852 · Cited by 64
Low-fat diets are preferred
Jéquier, E., & Bray, G. A. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(01)00991-3 · Cited by 63
Energy expenditure during overfeeding
Joosen, A. M., & Westerterp, K. R. (2006) · Nutrition & Metabolism · doi:10.1186/1743-7075-3-25 · Cited by 59
Why do some overweight children remain overweight, whereas others do not?
Wang, Y., Ge, K., & Popkin, B. M. (2003) · Public Health Nutrition · doi:10.1079/phn2003470 · Cited by 59
Role of dietary carbohydrate and frequent eating in body-weight control
Kirk, T. R. (2000) · Proceedings of The Nutrition Society · doi:10.1017/s0029665100000409 · Cited by 58
Fat digestion and absorption in spice‐pretreated rats
Prakash, U. N., & Srinivasan, K. (2012) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4597 · Cited by 62
Prolonged fasting significantly changes nutrient oxidation and glucose tolerance after a normal mixed meal
Horton, T. J., & Hill, J. O. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.1.155 · Cited by 57
Self-citation
Specific appetite, energetic and metabolomics responses to fat overfeeding in resistant-to-bodyweight-gain constitutional thinness
Germain, N., Galusca, B., Caron‐Dorval, D., Martin, J.-F., Pujos‐Guillot, E., Boirie‌, Y., Khalfallah, Y., Ling, Y., MINNION, J. S., Bloom, S. R., et al. (2014) · Nutrition and Diabetes · doi:10.1038/nutd.2014.17 · Cited by 56
Early responses of insulin signaling to high-carbohydrate and high-fat overfeeding
Adochio, R., Leitner, J. W., Gray, K., Draznin, B., & Cornier, M. (2009) · Nutrition & Metabolism · doi:10.1186/1743-7075-6-37 · Cited by 58
Consequences of food energy excess and positive energy balance
Uauy, R. D., & Díaz-Bautista, E. (2005) · Public Health Nutrition · doi:10.1079/phn2005797 · Cited by 57
Metabolic flexibility is impaired in women who are pregnant and overweight/obese and related to insulin resistance and inflammation
Tinius, R. A., Blankenship, M. M., Furgal, K. E., Cade, W. T., Pearson, K. J., Rowland, N. S., Pearson, R. C., Hoover, D. L., & Maples, J. M. (2020) · Metabolism · doi:10.1016/j.metabol.2020.154142 · Cited by 54
Imprecise control of energy intake: Absence of a reduction in food intake following overfeeding in young adults
Levitsky, D. A., Obarzanek, E., Mrdjenovic, G., & Strupp, B. J. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.01.004 · Cited by 54
Sucrose compared with artificial sweeteners: a clinical intervention study of effects on energy intake, appetite, and energy expenditure after 10 wk of supplementation in overweight subjects
Sørensen, L. B., Vasilaras, T. H., Astrup, A. V., & Raben, A. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.081554 · Cited by 54
Obesity: Overview of an Epidemic
Hill, J. O., Catenacci, V. A., & Wyatt, H. R. (2005) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2004.09.010 · Cited by 51
Self-citation
Physiology of Fat Replacement and Fat Reduction: Effects of Dietary Fat and Fat Substitutes on Energy Regulation
Roberts, S. B., Pi-Sunyer, F. X., Dreher, M. L., Hahn, R., Hill, J. O., Kleinman, R. E., Peters, J. C., Ravussin, É., Rolls, B. J., Yetley, E. A. D., et al. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1998.tb01730.x · Cited by 50
Self-citation
Overnutrition, Hyperinsulinemia and Ectopic Fat: It Is Time for A Paradigm Shift in the Management of Type 2 Diabetes
Janssen, J. A. M. J. L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105488 · Cited by 70
The effects of short-term overfeeding on insulin action in lean and reduced-obese individuals
Cornier, M., Bergman, B. C., & Bessesen, D. H. (2006) · Metabolism · doi:10.1016/j.metabol.2006.05.003 · Cited by 51
d-Xylose suppresses adipogenesis and regulates lipid metabolism genes in high-fat diet–induced obese mice
Lim, E., Lim, J. Y., Shin, J.-H., Seok, P. R., Jung, S., Yoo, S., & Kim, Y. (2015) · Nutrition Research · doi:10.1016/j.nutres.2015.05.012 · Cited by 48
1H NMR-based metabolomics approach reveals metabolic alterations in response to dietary imbalances in Megalobrama amblycephala
Prathomya, P., Prisingkorn, W., Jakovlić, I., Deng, F.-Y., Zhao, Y., & Wang, W. (2017) · Metabolomics · doi:10.1007/s11306-016-1158-7 · Cited by 48
Perception, passive overfeeding and energy metabolism
Westerterp, K. R. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.12.014 · Cited by 48
Fructose-Containing Sugars, Blood Pressure, and Cardiometabolic Risk: A Critical Review
Ha, V., Jayalath, V. H., Cozma, A. I., Mirrahimi, A., de Souza, R. J., & Sievenpiper, J. L. (2013) · Current Hypertension Reports · doi:10.1007/s11906-013-0364-1 · Cited by 45
Metabolic efficiency and energy expenditure during short-term overfeeding
Joosen, A. M. C. P., Bakker, A. H. F., & Westerterp, K. R. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.06.006 · Cited by 45
Physical Activity, Fat Balance, and Energy Balance
Hill, J. O., & Commerford, R. (1996) · International Journal of Sport Nutrition · doi:10.1123/ijsn.6.2.80 · Cited by 49
Self-citation
The Effects of Overfeeding on Body Composition: The Role of Macronutrient Composition - A Narrative Review
Leaf, A., & António, J. (2017) · International journal of exercise science · doi:10.70252/hppf5281 · Cited by 43
Dietary Fat Increases Energy Intake Across the Range of Typical Consumption in the United States
Donahoo, W. T., Wyatt, H. R., Kriehn, J., Stuht, J., Dong, F., Hosokawa, P. W., Grunwald, G. K., Johnson, S. L., Peters, J. C., & Hill, J. O. (2008) · Obesity · doi:10.1038/oby.2007.31 · Cited by 45
Self-citation
Carbohydrates and Energy Balance
Stubbs, R. J., Prentice, A. M., & James, W. P. T. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51798.x · Cited by 44
Dietary fat intake and body mass index in Spanish children
Moreno, L. A., Sarría, A., Lázaro, A., & Bueno, M. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.5.1399s · Cited by 43
Modelling olanzapine-induced weight gain in rats
van der Zwaal, E. M., Janhunen, S. K., la Fleur, S. E., & Adan, R. A. H. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114571300093x · Cited by 43
Prevalence and Correlates of Preschool Overweight and Obesity Amidst the Nutrition Transition: Findings from a National Cross-Sectional Study in Lebanon
Nasreddine, L., Hwalla, N. C., Saliba, A. E., Akl, C., & Naja, F. (2017) · Nutrients · doi:10.3390/nu9030266 · Cited by 43
Altered Hypothalamic Signaling and Responses to Food Deprivation in Rats Fed a Low‐Carbohydrate Diet
Kinzig, K. P., Scott, K. A., Hyun, J., Bi, S., & Moran, T. H. (2005) · Obesity Research · doi:10.1038/oby.2005.205 · Cited by 42
Pleasure junkies all around! Why it matters and why ‘the arts’ might be the answer: a biopsychological perspective
Christensen, J. F. (2017) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2016.2837 · Cited by 41
1H NMR-based metabolite profiling of diet-induced obesity in a mouse mode
Jung, J., Kim, I.-Y., Kim, Y.-N., Kim, J., Shin, J.-H., Jang, Z.-H., Lee, H.-S., Hwang, G., & Seong, J. K. (2012) · BMB Reports · doi:10.5483/bmbrep.2012.45.7.248 · Cited by 40
Changes in Gene Expression in Skeletal Muscle in Response to Fat Overfeeding in Lean Men
Meugnier, E., Bossu, C., Oliel, M., Jeanne, S., Michaut, A., Sothier, M., Brozek, J., Rome, S., Laville, M., & Vidal, H. (2007) · Obesity · doi:10.1038/oby.2007.310 · Cited by 44
Effects of (−)-hydroxycitrate on net fat synthesis as de novo lipogenesis
Kovacs, E. M. R., & Westerterp‐Plantenga, M. S. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2006.04.005 · Cited by 40
Metabolic response to fasting predicts weight gain during low-protein overfeeding in lean men: further evidence for spendthrift and thrifty metabolic phenotypes
Hollstein, T., Ando, T., Basolo, A., Krakoff, J. A., Votruba, S. B., & Piaggi, P. (2019) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqz062 · Cited by 38
Effects of 14 d of covert substitution of olestra for conventional fat on spontaneous food intake
Hill, J., Seagle, H. M., Johnson, S., Smith, S. R., Reed, G., Tran, Z. V., Cooper, D. A., Stone, M., & Peters, J. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/67.6.1178 · Cited by 38
Self-citation
Effects of dietary energy level on appetite and central adenosine monophosphate-activated protein kinase (AMPK) in broilers
Hu, X., Wang, Y., Sheikhahmadi, A., Li, X., Buyse, J. G., Lin, H., & Song, Z. (2019) · Journal of Animal Science · doi:10.1093/jas/skz312 · Cited by 40
Glycemic Carbohydrate and Body Weight Regulation
Saris, W. H. M. (2003) · Nutrition Reviews · doi:10.1301/nr.2003.may.s10-s16 · Cited by 37
Dietary fat and body weight control
Peters, J. C. (2003) · Lipids · doi:10.1007/s11745-003-1041-9 · Cited by 37
Self-citation
Inhibitory effect of gymnemic acid on intestinal absorption of oleic acid in rats
Wang, L. F., Luo, H., Miyoshi, M., Imoto, T., Hiji, Y., & Sasaki, T. (1998) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-76-10-11-1017 · Cited by 36
Increasing Dietary Fat Elicits Similar Changes in Fat Oxidation and Markers of Muscle Oxidative Capacity in Lean and Obese Humans
Bergouignan, A., Gozansky, W. S., Barry, D. W., Leitner, W., MacLean, P. S., Hill, J. O., Draznin, B., & Melanson, E. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030164 · Cited by 36
Self-citation
Metabolic response to small and large13C-labelled pasta meals following rest or exercise in man
Folch, N., Péronnet, F., Massicotte, D., Duclos, M., Lavoie, C., & Hillaire‐Marcel, C. (2001) · British Journal Of Nutrition · doi:10.1079/bjn2001325 · Cited by 36
Regulation of Energy Metabolism and Mitochondrial Function in Skeletal Muscle During Lipid Overfeeding in Healthy Men
Seyssel, K., Alligier, M., Meugnier, E., Chanséaume, E., Loizon, E., Cantó, C., Disse, E., Lambert-Porcheron, S., Brozek, J., Blond, E., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-4379 · Cited by 35
Long-term optional ingestion of corn oil induces excessive caloric intake and obesity in mice
Takeda, M., Imaizumi, M., Sawano, S., Manabe, Y., & Fushiki, T. (2001) · Nutrition · doi:10.1016/s0899-9007(00)00513-x · Cited by 35
Nutrition in patients with Type 2 diabetes: are low‐carbohydrate diets effective, safe or desirable?
Kennedy, R. L., Chokkalingam, K., & Farshchi, H. R. (2005) · Diabetic Medicine · doi:10.1111/j.1464-5491.2005.01594.x · Cited by 35
Exposure to an obesity-inducing diet early affects the pattern of expression of peroxisome proliferator, retinoic acid, and triiodothyronine nuclear receptors in the rat
Redonnet, A., Groubet, R., Nöel-Suberville, C., Bonilla, S., Martı́nez, A., & Higueret, P. (2001) · Metabolism · doi:10.1053/meta.2001.26759 · Cited by 34
Comparison of Methods for Achieving 24‐Hour Energy Balance in a Whole‐Room Indirect Calorimeter
Grunwald, G. K., Melanson, E. L., Forster, J. E., SEAGLE, H. M., Sharp, T. A., & Hill, J. O. (2003) · Obesity Research · doi:10.1038/oby.2003.105 · Cited by 33
Self-citation
Exercise before breakfast increases 24-h fat oxidation in female subjects
Iwayama, K., Kawabuchi, R., Nabekura, Y., Kurihara, R., Park, I., Kobayashi, M., Ogata, H., Kayaba, M., Omi, N., Satoh, M., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180472 · Cited by 32
Balanced intakes of natural triglycerides for optimum nutrition: an evolutionary and phytochemical perspective
Broadhurst, C. L. (1997) · Medical Hypotheses · doi:10.1016/s0306-9877(97)90210-3 · Cited by 32
Heat Stress Reduces Metabolic Rate While Increasing Respiratory Exchange Ratio in Growing Pigs
Fausnacht, D. W., Kroscher, K. A., McMillan, R. P., Martello, L. S., Baumgard, L. H., Selsby, J. T., Hulver, M. W., & Rhoads, R. P. (2021) · Animals · doi:10.3390/ani11010215 · Cited by 31
Metabolic adaptation is not observed after 8 weeks of overfeeding but energy expenditure variability is associated with weight recovery
Johannsen, D. L., Marlatt, K. L., Conley, K. E., Smith, S. R., & Ravussin, É. (2019) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqz108 · Cited by 30
How adaptations of substrate utilization regulate body composition
Hall, K. D., Bain, H., & Chow, C. C. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803608 · Cited by 30
Leptin pulsatility in formerly obese women
Mingrone, G., Manco, M., Granato, L., Calvani, M., Scarfone, A., Valera-Mora, E., Greco, A. V., Vidal, H., Castagneto, M., & Ferrannini, E. (2005) · The FASEB Journal · doi:10.1096/fj.04-3453fje · Cited by 28
Models of body weight and fatness regulation
Speakman, J. R., & Hall, K. D. (2023) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2022.0231 · Cited by 30
Common questions and misconceptions about protein supplementation: what does the scientific evidence really show?
António, J., Evans, C., Ferrando, A. A., Stout, J. R., Antonio, B. B., Cintineo, H. P., Harty, P. S., Arent, S. M., Candow, D. G., Forbes, S. C., et al. (2024) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2024.2341903 · Cited by 35
Regulation of Insulin Action by Diet and Exercise
Schmidt, S. L., & Hickey, M. S. (2009) · Journal of Equine Veterinary Science · doi:10.1016/j.jevs.2009.04.185 · Cited by 26
Shared genetic etiology between Parkinson’s disease and blood levels of specific lipids
Xicoy, H., Klemann, C. J. H. M., Witte, W. D., Martens, M. B., Martens, G. J. M., & Poelmans, G. (2021) · npj Parkinson s Disease · doi:10.1038/s41531-021-00168-9 · Cited by 24
Promotion of dietary carbohydrate as an approach to weight maintenance after initial weight loss: a pilot study
Kirk, T. R., Crombie, N. E., & Mc, C. (2000) · Journal of Human Nutrition and Dietetics · doi:10.1046/j.1365-277x.2000.00237.x · Cited by 23
Synthesis of fat in response to alterations in diet: Insights from new stable isotope methodologies
Hellerstein, M. K. (1996) · Lipids · doi:10.1007/bf02637062 · Cited by 23
The influence of adjustment for energy misreporting on relations of cake and cookie intake with cardiometabolic disease risk factors
Gottschald, M., Knüppel, S., Boeing, H., & Buijsse, B. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.131 · Cited by 22
Ad libitum intake of a high-carbohydrate or high-fat diet in young men: effects on nutrient balances
Proserpi, C., Sparti, A., Schutz, Y., Vetta, V. D., Milon, H., & Jéquier, E. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.3.539 · Cited by 22
Coherent, Preventive and Management Strategies for Obesity
Bray, G. A. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514962.ch14 · Cited by 21
Center for Demography and Ecology
Velyvis, K. A., Thompson‐Colón, T., & Winsborough, H. H. (2006) · Cited by 22
Regulation of macronutrient balance in healthy young and older men
Davy, K., Horton, T., Davy, B., Bessessen, D., & Hill, J. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801718 · Cited by 21
Self-citation
[Response to a weight control program based on approximating the diet to its theoretical ideal].
Ortega, R. M., López-Sobaler, A. M., Rodríguez‐Rodríguez, E., Bermejo, L. M., González, L. G., & Plaza, B. L. (2005) · PubMed · Cited by 21
A long-term mechanistic computational model of physiological factors driving the onset of type 2 diabetes in an individual
Sarkar, J., Dwivedi, G., Chen, Q., Sheu, I. E., Paich, M., Chelini, C. M., D'Alessandro, P. M., & Burns, S. P. (2018) · PLoS ONE · doi:10.1371/journal.pone.0192472 · Cited by 21
miR-21-3p Targets Elovl5 and Regulates Triglyceride Production in Mammary Epithelial Cells of Cow
Li, X., Jiang, P., Yu, H., Yang, Y., Xia, L., Yang, R., Fang, X., & Zhao, Z. (2019) · DNA and Cell Biology · doi:10.1089/dna.2018.4409 · Cited by 20
The effect of ethanol on pancreatic enzymes–a dietary artefact?
Apte, M. V., Norton, I. D., Haber, P., Applegate, T. L., Korsten, M. A., McCaughan, G. W., Pirola, R. C., & Wilson, J. S. (1998) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(97)00109-8 · Cited by 20
Rapid prediction and identification of lipase inhibitors in volatile oil from Pinus massoniana L. needles
Wang, M., Gu, D., Li, H., Wang, Q., Kang, J., Chu, T., Guo, H., Yang, Y., & Tian, J. (2017) · Phytochemistry · doi:10.1016/j.phytochem.2017.06.002 · Cited by 19
The different satiating capacity of CHO and fats can be mediated by different effects on leptin and ghrelin systems
Sánchez, J., Cladera, M. M., Llopis, M., Palou, A., & Picó, C. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.04.051 · Cited by 19
The Influence of Herbs, Spices, and Regular Sausage and Chicken Consumption on Liking of Reduced Fat Breakfast and Lunch Items
Polsky, S., Courtney, J. B., Stark, R. A., Pan, Z., Hill, J. O., & Peters, J. C. (2014) · Journal of Food Science · doi:10.1111/1750-3841.12643 · Cited by 19
Self-citation
Sleep duration modifies effects of free ad libitum school meals on adiposity and blood pressure
Hjorth, M. F., Sjödin, A. M., Dalskov, S., Damsgaard, C. T., Michaelsen, K. F., Biltoft-Jensen, A. P., Andersen, R., Ritz, C., Chaput, J., & Astrup, A. V. (2015) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0319 · Cited by 19
Twenty-four hour energy expenditure and substrate oxidation before and after 6 months' ad libitum intake of a diet rich in simple or complex carbohydrates or a habitual diet
Vasilaras, T. H., Raben, A., & Astrup, A. V. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801630 · Cited by 19
A role for olestra in body weight management
Eldridge, A. L., Cooper, D. A., & Peters, J. C. (2002) · Obesity Reviews · doi:10.1046/j.1467-789x.2002.00050.x · Cited by 19
Self-citation
Diet-gut microbiome interaction and its impact on host blood glucose homeostasis: a series of nutritional n-of-1 trials
Fu, Y., Gou, W., Zhong, H., Tian, Y., Zhao, H., Liang, X., Shuai, M., Zhuo, L., Jiang, Z., Tang, J., et al. (2024) · EBioMedicine · doi:10.1016/j.ebiom.2024.105483 · Cited by 20
A one month high fat diet disrupts the gut microbiome and integrity of the colon inducing adiposity and behavioral despair in male Sprague Dawley rats
Chompré, G., Sambolin‐Escobales, L., Cruz, M. L., Sanchez, R., Rodriguez, Y., Rodríguez-Santiago, R. E., Yamamura, Y., & Appleyard, C. B. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e11194 · Cited by 17
Carbohydrate-insulin model: does the conventional view of obesity reverse cause and effect?
Ludwig, D. S. (2023) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2022.0211 · Cited by 22
Dietary fat alters the response of hypothalamic neuropeptide Y to subsequent energy intake in broiler chickens
Wang, X. J., Xu, S. H., Liu, L., Song, Z. G., Jiao, H., & Lin, H. (2016) · Journal of Experimental Biology · doi:10.1242/jeb.143792 · Cited by 19
Causes of obesity
Martínez, J. A., Moreno, M. J., Marques-Lopes, I., & Martí, A. (2009) · Anales del Sistema Sanitario de Navarra · doi:10.23938/assn.0811 · Cited by 18
Is the control of fat ingestion sexually differentiated?
Geary, N. (2004) · Physiology and Behavior · doi:10.1016/j.physbeh.2004.08.041 · Cited by 18
Increased aerobic capacity reduces susceptibility to acute high‐fat diet‐induced weight gain
Morris, E. M., Meers, G. M.-E., Koch, L. G., Britton, S. L., MacLean, P. S., & Thyfault, J. P. (2016) · Obesity · doi:10.1002/oby.21564 · Cited by 18
Appropriate protein intake is one strategy in the management of metabolic syndrome in Korean elderly to mitigate changes in body composition
Oh, C., & No, J.-K. (2017) · Nutrition Research · doi:10.1016/j.nutres.2017.12.008 · Cited by 18
Effects of Dietary Conjugated Linoleic Acid and Biopolymer Encapsulation on Lipid Metabolism in Mice
Hur, S. J., Kim, D., Chun, S. C., & Lee, S. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms14046848 · Cited by 17
Low‐ and High‐Carbohydrate Diets: Body Composition Differences in Rats
McNeel, R. L., & Mersmann, H. J. (2005) · Obesity Research · doi:10.1038/oby.2005.203 · Cited by 18
Current Knowledge of the Health Effects of Sugar Intake
Mardis, A. L. (2001) · Cited by 17
Feedback models allowing estimation of thresholds for self-promoting body weight gain
Christiansen, E., Swann, A., & Sørensen, T. I. A. (2008) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2008.07.004 · Cited by 18
Hypothesis: parents may selectively restrict sugar-containing foods for pre-school children with a high BMI
Gibson, S. A. (1998) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637489809086405 · Cited by 16
Postgraduate Symposium The role of fat in gastric emptying and satiety: acute and chronic effects
Clegg, M., & Shafat, A. (2009) · Proceedings of The Nutrition Society · doi:10.1017/s0029665108008859 · Cited by 15
Increased Intake of Dietary Polyunsaturated Fat Does Not Promote Whole Body or Preferential Abdominal Fat Mass Loss in Overweight Adults
Tan, S., Batterham, M. J., & Tapsell, L. C. (2011) · Obesity Facts · doi:10.1159/000333433 · Cited by 15
Affective Pavlovian motivation is enhanced in obesity susceptible populations: Implications for incentive motivation in obesity
Derman, R. C., & Ferrario, C. R. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.112318 · Cited by 17
Etiologies of Obesity
Atkinson, R. L. (2005) · Humana Press eBooks · doi:10.1385/1-59259-865-x:105 · Cited by 15
Obesity: prevalence, causes, health risks and treatment
Green, S. M. (1997) · British Journal of Nursing · doi:10.12968/bjon.1997.6.20.1181 · Cited by 15
Assessing the evidence for weight loss strategies in people with and without type 2 diabetes
Clifton, P. M. (2017) · World Journal of Diabetes · doi:10.4239/wjd.v8.i10.440 · Cited by 15
Maintenance on a ketogenic diet: voluntary exercise, adiposity and neuroendocrine effects
Kinzig, K. P., & Taylor, R. J. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.109 · Cited by 14

Authors: Horton, T., Drougas, H., Brachey, A., Reed, G., Peters, J., & Hill, J.
Affiliations: University of Colorado Health (US)
Venue: The American Journal of Clinical Nutrition
Publisher: Elsevier BV
Published: 1995-07
Volume: 62
Issue: 1
Pages: 19-29
ISSN: 0002-9165 (ISSN-L)
DOI: 10.1093/ajcn/62.1.19
OpenAlex: W1952443362
Cited by: 339
References: 38
Citations by year: 2026: 7 · 2025: 1 · 2024: 7 · 2023: 6 · 2022: 7 · 2021: 8 · 2020: 9 · 2019: 14 · 2018: 7 · 2017: 16 · 2016: 8 · 2015: 9 · 2014: 10 · 2013: 13 · 2012: 11
FWCI: 5.03
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: American Journal of Clinical Nutrition (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (DK-42549)
National Center for Research Resources (RR00095)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Keywords: energy storage, fat deposition, energy expenditure, carbohydrate oxidation, fat oxidation, nutrient oxidation, body weight regulation, obesity, lean men, energy balance
MeSH terms: Adolescent, Adult, Blood Glucose, Body Composition, Body Weight, Calorimetry, Dietary Carbohydrates, Dietary Fats, Energy Metabolism, Fasting, Fatty Acids, Nonesterified, Humans, Hyperphagia, Insulin, Male, Middle Aged, Obesity, Oxidation-Reduction, Cross-Over Studies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Fat and carbohydrate overfeeding in humans: different effects on energy storage

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks