L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: A randomized and controlled clinical trial
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In centenarians with weakness, decreasing mental health, impaired mobility, and poor endurance, taking 2 g of L-carnitine daily for six days reduced fat mass.
“patients taking 2 g of L-carnitine daily for six days had a reduction in fat mass”
From Novel Insights on Intake of Fish and Prevention of Sarcopenia: All Reasons for an Adequate Consumption (2020) · cites this paper as [97]
L-carnitine exerts an anti-inflammatory effect in several disease settings.
“L-carnitine exerts an anti-inflammatory effect in several disease settings”
From Novel Insights on Intake of Fish and Prevention of Sarcopenia: All Reasons for an Adequate Consumption (2020) · cites this paper as [97]
In centenarians with weakness, decreasing mental health, impaired mobility, and poor endurance, taking 2 g of L-carnitine daily for six days increased lean mass.
“and an increase in lean mass”
From Novel Insights on Intake of Fish and Prevention of Sarcopenia: All Reasons for an Adequate Consumption (2020) · cites this paper as [97]
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- Authors
- Malaguarnera, M., Cammalleri, L., Gargante, M. P., Vacante, M., Colonna, V., & Motta, M.
- Affiliations
- University of Catania (IT)
- Corresponding author
- Malaguarnera, Mariano
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2007-12
- Volume
- 86
- Issue
- 6
- Pages
- 1738-1744
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W1820460245
- Cited by
- 142
- References
- 39
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 5 · 2023: 9 · 2022: 13 · 2021: 10 · 2020: 15 · 2019: 10 · 2018: 4 · 2017: 7 · 2016: 8 · 2015: 6 · 2014: 9 · 2013: 5 · 2012: 6
- FWCI
- 2.53
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- UCLA - Biblioteca de Ciencias de la Salud (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Keywords
- L-carnitine, centenarians, physical fatigue, mental fatigue, cognitive function, muscle mass, fat mass, acylcarnitines, cellular energy metabolism, aging
- MeSH terms
- Adipose Tissue, Aged, 80 and over, Aging, Blood Pressure, Carnitine, Cholesterol, Cognition, Creatine Kinase, Creatinine, Double-Blind Method, Fatigue, Female, Heart Rate, Humans, L-Lactate Dehydrogenase, Male, Muscles, Triglycerides
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