GOLD—Graphical Overview of Linkage Disequilibrium

Prospects for whole-genome linkage disequilibrium mapping of common disease genes

Kruglyak, L. (1999) · Nature Genetics · doi:10.1038/9642 · Cited by 1,416

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

Scuteri, A., Sanna, S., Chen, W.-M., Uda, M., Albai, G., Strait, J., Najjar, S., Nagaraja, R., Orrú, M., Usala, G., et al. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030115 · Cited by 1,724

Linkage disequilibrium--understanding the evolutionary past and mapping the medical future.

Slatkin, M. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2361 · Cited by 1,614

A Simple Correction for Multiple Testing for Single-Nucleotide Polymorphisms in Linkage Disequilibrium with Each Other

Nyholt, D. R. (2004) · The American Journal of Human Genetics · doi:10.1086/383251 · Cited by 1,699

A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes

Cargill, M., Schrodi, S. J., Chang, M., Garcia, V. E., Brandon, R., Callis, K. P., Matsunami, N., Ardlie, K. G., Civello, D., Catanese, J. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/511051 · Cited by 1,086

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia

Uda, M., Galanello, R., Sanna, S., Lettre, G., Sankaran, V. G., Chen, W., Usala, G., Busonero, F., Maschio, A., Albai, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711566105 · Cited by 672

Variations in GABRA2, Encoding the α2 Subunit of the GABAA Receptor, Are Associated with Alcohol Dependence and with Brain Oscillations

Edenberg, H. J., Dick, D. M., Xuei, X., Tian, H., Almasy, L., Bauer, L. O., Crowe, R. R., Goate, A., Hesselbrock, V., Jones, K., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/383283 · Cited by 655

Interleukin 7 receptor α chain ( IL7R ) shows allelic and functional association with multiple sclerosis

for the Multiple Sclerosis Genetics Group, Gregory, S. G., Schmidt, S., Seth, P., Oksenberg, J. R., Hart, J., Prokop, A., Caillier, S. J., Ban, M., Goris, A., et al. (2007) · Nature Genetics · doi:10.1038/ng2103 · Cited by 657

A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration

Kanda, A., Chen, W., Othman, M., Branham, K. E. H., Brooks, M., Khanna, R., He, S., Lyons, R., Abecasis, G. R., & Swaroop, A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0703933104 · Cited by 441

Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study

Tanaka, T., Shen, J., Abecasis, G. R., Kisialiou, A., Ordovas, J. M., Guralnik, J. M., Singleton, A., Bandinelli, S., Cherubini, A., Arnett, D., et al. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000338 · Cited by 418

CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

Li, M., Atmaca-Sonmez, P., Othman, M., Branham, K. E. H., Khanna, R., Wade, M. S., Li, Y., Liang, L., Zareparsi, S., Swaroop, A., et al. (2006) · Nature Genetics · doi:10.1038/ng1871 · Cited by 354

Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus

Heijmans, B. T., Kremer, D., Tobi, E. W., Boomsma, D. I., & Slagboom, P. E. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm010 · Cited by 238

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

Saccone, N. L., Saccone, S. F., Hinrichs, A. L., Stitzel, J. A., Duan, W., Pergadia, M. L., Agrawal, A., Breslau, N., Grucza, R. A., Hatsukami, D., et al. (2009) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30828 · Cited by 215

Functional Candidate Genes in Age-Related Macular Degeneration: Significant Association with VEGF,VLDLR, and LRP6

Haines, J. L., Schnetz-Boutaud, N., Schmidt, S., Scott, W. K., Agarwal, A., Postel, E. A., Olson, L., Kenealy, S. J., Hauser, M., Gilbert, J. R., et al. (2006) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.05-0116 · Cited by 189

C957T polymorphism of dopamine D2 receptor gene affects striatal DRD2 in vivo availability by changing the receptor affinity

Hirvonen, M. M., Laakso, A., Någren, K., Rinne, J. O., Pohjalainen, T., & Hietala, J. (2009) · Synapse · doi:10.1002/syn.20672 · Cited by 176

Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function

Arnaud-Lopez, L., Usala, G., Ceresini, G., Mitchell, B. D., Pilia, M. G., Piras, M. G., Sestu, N., Maschio, A., Busonero, F., Albai, G., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.04.019 · Cited by 139

Extended linkage disequilibrium surrounding the hemoglobin E variant due to malarial selection

Ohashi, J., Naka, I., Patarapotikul, J., Hananantachai, H., Brittenham, G., Looareesuwan, S., Clark, A. G., & Tokunaga, K. (2004) · The American Journal of Human Genetics · doi:10.1086/421330 · Cited by 137

Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction

Yuferov, V., Fussell, D., LaForge, K. S., Nielsen, D. A., Gordon, D., Ho, A., Leal, S. M., Ott, J., & Kreek, M. J. (2004) · Pharmacogenetics · doi:10.1097/00008571-200412000-00002 · Cited by 128

Impact of interacting functional variants in COMT on regional gray matter volume in human brain

Honea, R., Verchinski, B. A., Pezawas, L., Kolachana, B. S., Callicott, J. H., Mattay, V. S., Weinberger, D. R., & Meyer-Lindenberg, A. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.10.064 · Cited by 128

Screening of nine candidate genes for autism on chromosome 2q reveals rare nonsynonymous variants in the cAMP-GEFII gene

Bacchelli, E., Blasi, F., Biondolillo, M., Lamb, J. A., Bonora, E., Barnby, G., Parr, J., Beyer, K. S., Klauck, S. M., Poustka, A., et al. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001340 · Cited by 117

COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association Scan

Tarasov, K. V., Sanna, S., Scuteri, A., Strait, J. B., Orrù, M., Parsa, A., Lin, P.-I., Maschio, A., Lai, S., Piras, M. G., et al. (2009) · Circulation: Cardiovascular Genetics · doi:10.1161/circgenetics.108.823245 · Cited by 104

Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk

Zhang, L., Rao, F., Zhang, K., Khandrika, S., Das, M., Vaingankar, S. M., Bao, X., Rana, B. K., Smith, D. W., Wessel, J., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31093 · Cited by 90

Linkage disequilibrium, haplotype and association studies of a chromosome 4 GABA receptor gene cluster: candidate gene variants for addictions

Drgon, T., D'Addario, C., & Uhl, G. R. (2006) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30349 · Cited by 82

Association between the neuron-specific RNA-binding protein ELAVL4 and Parkinson disease

Noureddine, M. A., Qin, X.-J., Oliveira, S. A., Skelly, T. J., van der Walt, J., Hauser, M. A., Pericak-Vance, M. A., Vance, J. M., & Li, Y.-J. (2005) · Human Genetics · doi:10.1007/s00439-005-1259-2 · Cited by 76

Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease

Shibata, N., Kawarai, T., Lee, J. H., Lee, H.-S., Shibata, E., Sato, C., Liang, Y., Duara, R., Mayeux, R. P., St George-Hyslop, P. H., et al. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2005.08.048 · Cited by 59

Association study of two genetic variants in mitochondrial transcription factor A (TFAM) in Alzheimer's and Parkinson's disease

Belin, A. C., Björk, B. F., Westerlund, M., Galter, D., Sydow, O., Lind, C., Pernold, K., Rosvall, L., Håkansson, A., Winblad, B., et al. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.05.010 · Cited by 48

Quantitative Trait Loci Mapping in Plants: Concepts and Approaches

Sehgal, D., Singh, R., & Rajpal, V. R. (2016) · Sustainable Development and Biodiversity · doi:10.1007/978-3-319-27090-6_2 · Cited by 50

Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis

Rubio, J. P., Tubridy, N., Bahlo, M., Stankovich, J., Burfoot, R., Butzkueven, H., Chapman, C., Johnson, L., Marriott, M., Mraz, G., et al. (2004) · Human Genetics · doi:10.1007/s00439-004-1095-9 · Cited by 43

Examination of the clock gene cryptochrome 1 in bipolar disorder: mutational analysis and absence of evidence for linkage or association

Nievergelt, C. M., Kripke, D. F., Remick, R. A., Sadovnick, A. D., McElroy, S. L., Keck, P. E., & Kelsoe, J. R. (2005) · Psychiatric Genetics · doi:10.1097/00041444-200503000-00008 · Cited by 38

Association study between the TNXB locus and schizophrenia in a Japanese population

Tochigi, M., Zhang, X., Ohashi, J., Hibino, H., Otowa, T., Rogers, M., Kato, T., Okazaki, Y., Kato, N., Tokunaga, K., et al. (2007) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30441 · Cited by 25

Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen

Timmann, C., Fuchs, S., Thoma, C., Lepping, B., Brattig, N. W., Sievertsen, J., Thye, T., Müller-Myhsok, B., & Horstmann, R. D. (2004) · Genes & Immunity · doi:10.1038/sj.gene.6364094 · Cited by 17

Association analysis of genes involved in cholesterol metabolism located within the linkage region on chromosome 10 and Alzheimer’s disease

Riemenschneider, M., Mahmoodzadeh, S., Eisele, T., Klopp, N., Schwarz, S., Wagenpfeil, S., Diehl, J., Mueller, U., Foerstl, H., Illig, T., et al. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.01.001 · Cited by 14

Chromosome 11‐q24 region in Tourette syndrome: Association and linkage disequilibrium study in the French Canadian population

Díaz‐Anzaldúa, A., Rivière, J., Dubé, M., Joober, R., Saint‐Onge, J., Dion, Y., Lespérance, P., Richer, F., Chouinard, S., Rouleau, G. A., et al. (2005) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.30928 · Cited by 11