Gamma oscillations in the hippocampus require high complex I gene expression and strong functional performance of mitochondria

A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Wallace, D. C. (2005) · Annual Review of Genetics · doi:10.1146/annurev.genet.39.110304.095751 · Cited by 3,185

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

Cardin, J. A., Carlén, M., Meletis, K., Knoblich, U., Zhang, F., Deisseroth, K., Tsai, L.-H., & Moore, C. I. (2009) · Nature · doi:10.1038/nature08002 · Cited by 2,603

Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks

Bartos, M., Vida, I., & Jonas, P. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2044 · Cited by 2,070

Effect of anoxia on ion distribution in the brain

Hansen, A. J. (1985) · Physiological Reviews · doi:10.1152/physrev.1985.65.1.101 · Cited by 1,342

Mitochondria in neuroplasticity and neurological disorders

Mattson, M. P., Gleichmann, M., & Cheng, A. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.010 · Cited by 1,081

Mechanisms of Gamma Oscillations in the Hippocampus of the Behaving Rat

Csicsvari, J., Jamieson, B. G., Wise, K. D., & Buzsáki, G. (2003) · Neuron · doi:10.1016/s0896-6273(02)01169-8 · Cited by 1,031

The neural basis of functional brain imaging signals

Attwell, D., & Iadecola, C. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02264-6 · Cited by 957

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

Mootha, V. K., Bunkenborg, J., Olsen, J. V., Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00926-7 · Cited by 889

Cholinergic induction of network oscillations at 40 Hz in the hippocampus in vitro

Fisahn, A., Pike, F. G., Buhl, E. H., & Paulsen, O. (1998) · Nature · doi:10.1038/28179 · Cited by 884

Mitochondria and neuronal activity

Kann, O., & Kovács, R. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00222.2006 · Cited by 871

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Zeisel, A., Muñoz-Manchado, A. B., Codeluppi, S., Lönnerberg, P., La Manno, G., Juréus, A., Marques, S., Munguba, H., He, L., Betsholtz, C., et al. (2015) · Science · doi:10.1126/science.aaa1934 · Cited by 3,124

Highly energized inhibitory interneurons are a central element for information processing in cortical networks.

Kann, O., Papageorgiou, I. E., & Draguhn, A. (2014) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2014.104 · Cited by 295

The interneuron energy hypothesis: Implications for brain disease

Kann, O. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.08.005 · Cited by 270

Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A “central hub” in schizophrenia pathophysiology?

Steullet, P., Cabungcal, J. H., Monin, A., Dwir, D., O'Donnell, P., Cuenod, M., & Do, K. Q. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2014.06.021 · Cited by 262

Mitochondrial Dysfunction in Parkinson’s Disease—Cause or Consequence?

Chen, C., Turnbull, D. M., & Reeve, A. K. (2019) · Biology · doi:10.3390/biology8020038 · Cited by 260

Mitochondrial dysfunction and seizures: the neuronal energy crisis

Zsurka, G., & Kunz, W. S. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00148-9 · Cited by 258

Parvalbumin interneuron vulnerability and brain disorders

Ruden, J. B., Dugan, L. L., & Konradi, C. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-020-0778-9 · Cited by 194

TLR4-activated microglia require IFN-γ to induce severe neuronal dysfunction and death in situ

Papageorgiou, I. E., Lewen, A., Galow, L. V., Cesetti, T., Scheffel, J., Regen, T., Hanisch, U., & Kann, O. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1513853113 · Cited by 225

Expression of microRNA-34a in Alzheimer’s disease brain targets genes linked to synaptic plasticity, energy metabolism, and resting state network activity

Sarkar, S., Jun, S., Rellick, S., Quintana, D. D., Cavendish, J. Z., & Simpkins, J. W. (2016) · Brain Research · doi:10.1016/j.brainres.2016.05.026 · Cited by 209

Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment

Blank, T., Detje, C. N., Spieß, A., Hagemeyer, N., Brendecke, S. M., Wolfart, J., Staszewski, O., Zöller, T., Papageorgiou, I. E., Schneider, J., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.04.005 · Cited by 182

The role of gamma oscillations in central nervous system diseases: Mechanism and treatment

Guan, A., Wang, S., Huang, A., Qiu, C., Li, Y., Li, X., Jinfei, W., Wang, Q., & Deng, B. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.962957 · Cited by 178

Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia

Do, K. Q., Cuenod, M., & Hensch, T. K. (2015) · Schizophrenia Bulletin · doi:10.1093/schbul/sbv065 · Cited by 158

Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ

Ta, T., Dikmen, H. O., Schilling, S., Chausse, B., Lewen, A., Hollnagel, J., & Kann, O. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1813562116 · Cited by 157

Does interneuronal dysfunction contribute to neurodegeneration in amyotrophic lateral sclerosis?

Turner, M. R., & Kiernan, M. C. (2012) · Amyotrophic Lateral Sclerosis · doi:10.3109/17482968.2011.636050 · Cited by 144

TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults

Kim, S. Y., Senatorov, V. V., Morrissey, C. S., Lippmann, K., Vazquez, O. N., Milikovsky, D. Z., Gu, F., Parada, I., Prince, D. A., Becker, A. J., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-07394-3 · Cited by 141

Towards a cognitive neuroscience of self-awareness

Lou, H. C., Changeux, J. P., & Rosenstand, A. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.04.004 · Cited by 131

Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia

Cuénod, M., Steullet, P., Cabungcal, J.-H., Dwir, D., Khadimallah, I., Klauser, P., Conus, P., & Kim, Q. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01374-w · Cited by 134

Perturbation of Brain Oscillations after Ischemic Stroke: A Potential Biomarker for Post-Stroke Function and Therapy

Rabiller, G., He, J.-W., Nishijima, Y., Wong, A. S. W., & Liu, J. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161025605 · Cited by 124

Ameliorating Mitochondrial Dysfunction of Neurons by Biomimetic Targeting Nanoparticles Mediated Mitochondrial Biogenesis to Boost the Therapy of Parkinson's Disease

Zheng, Q. Y., Liu, H., Zhang, H., Han, Y., Yuan, J., Wang, T., Gao, Y., & Li, Z. (2023) · Advanced Science · doi:10.1002/advs.202300758 · Cited by 117

Interstitial ions: A key regulator of state-dependent neural activity?

Rasmussen, R. N., O’Donnell, J., Ding, F., & Nedergaard, M. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101802 · Cited by 122

Mitochondrial diseases and epilepsy

Bindoff, L. A., & Engelsen, B. A. (2012) · Epilepsia · doi:10.1111/j.1528-1167.2012.03618.x · Cited by 110

Mitochondrial multifaceted dysfunction in schizophrenia; complex I as a possible pathological target

Ben‐Shachar, D. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.10.022 · Cited by 112

Severe nigrostriatal degeneration without clinical parkinsonism in patients with polymerase gamma mutations

Tzoulis, C., Tran, G. T., Schwarzlmüller, T., Specht, K., Haugarvoll, K., Balafkan, N., Lilleng, P. K., Miletić, H., Biermann, M., & Bindoff, L. A. (2013) · Brain · doi:10.1093/brain/awt103 · Cited by 103

A behavioral neuroenergetics theory of ADHD

Killeen, P. R., Russell, V. A., & Sergeant, J. A. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.02.011 · Cited by 97

Molecular pathogenesis of polymerase gamma–related neurodegeneration

Tzoulis, C., Tran, G. T., Coxhead, J., Bertelsen, B. I., Lilleng, P. K., Balafkan, N., Payne, B. A. I., Miletić, H., Chinnery, P. F., & Bindoff, L. A. (2014) · Annals of Neurology · doi:10.1002/ana.24185 · Cited by 92

m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity

Gunnewiek, T. M. K., van Hugte, E., Frega, M., Guardia, G. S., Foreman, K., Panneman, D. M., Mossink, B., Linda, K., Keller, J. M., Schubert, D., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107538 · Cited by 90

TLR2- and TLR3-activated microglia induce different levels of neuronal network dysfunction in a context-dependent manner

Schilling, S., Chausse, B., Dikmen, H. O., Almouhanna, F., Hollnagel, J., Lewen, A., & Kann, O. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.05.013 · Cited by 91

Mitochondrial Ca2+ uptake by the MCU facilitates pyramidal neuron excitability and metabolism during action potential firing

Groten, C. J., & MacVicar, B. A. (2022) · Communications Biology · doi:10.1038/s42003-022-03848-1 · Cited by 93

Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia

Jiang, Z., Cowell, R. M., & Nakazawa, K. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00116 · Cited by 91

Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia

Khadimallah, I., Jenni, R., Cabungcal, J.-H., Cleusix, M., Fournier, M., Béard, E., Klauser, P., Knebel, J., Murray, M. M., Retsa, C., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01313-9 · Cited by 89

Cerebral Energy Metabolism and the Brain’s Functional Network Architecture: An Integrative Review

Lord, L.-D., Expert, P., Huckins, J. F., & Turkheimer, F. (2013) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2013.94 · Cited by 86

Oxygen Consumption Rates during Three Different Neuronal Activity States in the Hippocampal CA3 Network

Huchzermeyer, C., Berndt, N., Holzhütter, H.-G., & Kann, O. (2013) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2012.165 · Cited by 81

Transgenic Overexpression of the Type I Isoform of Neuregulin 1 Affects Working Memory and Hippocampal Oscillations but not Long-term Potentiation

Deakin, I. H., Nissen, W., Law, A. J., Lane, T. A., Kanso, R., Schwab, M. H., Nave, K., Lamsa, K. P., Paulsen, O., Bannerman, D. M., et al. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr223 · Cited by 81

Critical State of Energy Metabolism in Brain Slices: The Principal Role of Oxygen Delivery and Energy Substrates in Shaping Neuronal Activity

Ivanov, A., & Zilberter, Y. (2011) · Frontiers in Neuroenergetics · doi:10.3389/fnene.2011.00009 · Cited by 80

Impaired mitochondrial function abolishes gamma oscillations in the hippocampus through an effect on fast-spiking interneurons

Whittaker, R. G., Turnbull, D. M., Whittington, M. A., & Cunningham, M. O. (2011) · Brain · doi:10.1093/brain/awr018 · Cited by 74

The role of astrocytes in seizure generation: insights from a novel in vitro seizure model based on mitochondrial dysfunction

Chan, F., Lax, N. Z., Voss, C. M., Aldana, B. I., Whyte, S., Jenkins, A. J., Nicholson, C., Nichols, S., Tilley, E., Powell, Z., et al. (2018) · Brain · doi:10.1093/brain/awy320 · Cited by 75

Aerobic production and utilization of lactate satisfy increased energy demands upon neuronal activation in hippocampal slices and provide neuroprotection against oxidative stress

Schurr, A. (2011) · Frontiers in Pharmacology · doi:10.3389/fphar.2011.00096 · Cited by 74

Oxidative Dysregulation in Early Life Stress and Posttraumatic Stress Disorder: A Comprehensive Review

Karanikas, E., Daskalakis, N. P., & Agorastos, A. (2021) · Brain Sciences · doi:10.3390/brainsci11060723 · Cited by 78

Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures

Simeone, K. A., Matthews, S. A., Samson, K. K., & Simeone, T. A. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.11.005 · Cited by 71

GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ

Dikmen, H. O., Hemmerich, M., Lewen, A., Hollnagel, J., Chausse, B., & Kann, O. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01903-4 · Cited by 69

Lactate Attenuates Synaptic Transmission and Affects Brain Rhythms Featuring High Energy Expenditure

Hollnagel, J., Cesetti, T., Schneider, J., Vazetdinova, A., Valiullina, F., Lewen, A., Rozov, A. V., & Kann, O. (2020) · iScience · doi:10.1016/j.isci.2020.101316 · Cited by 66

Synaptic energy metabolism and neuronal excitability, in sickness and health

Oyarzábal, A., & Marin‐Valencia, I. (2019) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12071 · Cited by 63

Extensive respiratory chain defects in inhibitory interneurones in patients with mitochondrial disease

Lax, N. Z., Grady, J., Laude, A., Chan, F., Hepplewhite, P. D., Gorman, G., Whittaker, R. G., Ng, Y., Cunningham, M. O., & Turnbull, D. M. (2016) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12238 · Cited by 61

Energy substrates that fuel fast neuronal network oscillations

Galow, L. V., Schneider, J., Lewen, A., Ta, T., Papageorgiou, I. E., & Kann, O. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00398 · Cited by 58

Synaptic Activity Drives a Genomic Program That Promotes a Neuronal Warburg Effect

Orth, C. B., Tan, Y.-W., Lau, D., & Bading, H. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.761106 · Cited by 56

Antibiotic-induced gut dysbiosis leads to activation of microglia and impairment of cholinergic gamma oscillations in the hippocampus

Çalışkan, G., French, T., Lacalle, S. E., del Ángel, M., Steffen, J., Heimesaat, M. M., Dunay, I. R., & Stork, O. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.10.007 · Cited by 58

Energy demand of synaptic transmission at the hippocampal Schaffer-collateral synapse

Liotta, A., Rösner, J., Huchzermeyer, C., Wojtowicz, A., Kann, O., Schmitz, D., Heinemann, U., & Kovács, R. (2012) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2012.116 · Cited by 48

The Energy Demand of Fast Neuronal Network Oscillations: Insights from Brain Slice Preparations

Kann, O. (2012) · Frontiers in Pharmacology · doi:10.3389/fphar.2011.00090 · Cited by 52

Non-signalling energy use in the developing rat brain

Engl, E., Jolivet, R., Hall, C. N., & Attwell, D. (2016) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x16648710 · Cited by 48

Bioenergetic Mechanisms of Seizure Control

Kovács, R., Gerevich, Z., Friedman, A., Otáhal, J., Prager, O., Gabriel, S., & Berndt, N. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00335 · Cited by 50

A potential role for glia‐derived extracellular matrix remodeling in postinjury epilepsy

Kim, S. Y., Porter, B. E., Friedman, A., & Kaufer, D. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23758 · Cited by 47

Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer’s pathology

Kumar, P., Goettemoeller, A. M., Espinosa‐García, C., Tobin, B. R., Tfaily, A., Nelson, R. S., Natu, A., Dammer, E. B., Santiago, J. V., Malepati, S., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47028-7 · Cited by 53

Redox Indicator Mice Stably Expressing Genetically Encoded Neuronal roGFP: Versatile Tools to Decipher Subcellular Redox Dynamics in Neuropathophysiology

Wagener, K. C., Kolbrink, B., Dietrich, K., Kizina, K. M., Terwitte, L. S., Kempkes, B., Bao, G., & Müller, M. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2015.6587 · Cited by 49

Interneuron Deficit Associates Attenuated Network Synchronization to Mismatch of Energy Supply and Demand in Aging Mouse Brains

Jessen, S. B., Mathiesen, C., Lind, B. L., & Lauritzen, M. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhv261 · Cited by 49

Taxifolin protects neurons against ischemic injury in vitro via the activation of antioxidant systems and signal transduction pathways of GABAergic neurons

Turovskaya, M. V., Gaidin, S. G., Mal’tseva, V. N., Зинченко, В. П., & Turovsky, E. A. (2019) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2019.01.005 · Cited by 45

A developmental redox dysregulation leads to spatio-temporal deficit of parvalbumin neuron circuitry in a schizophrenia mouse model

Cabungcal, J.-H., Steullet, P., Kraftsik, R., Cuénod, M., & Kim, Q. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.02.017 · Cited by 46

Lactate as a supplemental fuel for synaptic transmission and neuronal network oscillations: Potentials and limitations

Kann, O. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15867 · Cited by 44

Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra

Williams, A. C., Hill, L. J., & Ramsden, D. B. (2012) · Current Gerontology and Geriatrics Research · doi:10.1155/2012/302875 · Cited by 42

A reliable model for gamma oscillations in hippocampal tissue

Schneider, J., Lewen, A., Ta, T., Galow, L. V., Isola, R., Papageorgiou, I. E., & Kann, O. (2015) · Journal of Neuroscience Research · doi:10.1002/jnr.23590 · Cited by 41

Local oxygen homeostasis during various neuronal network activity states in the mouse hippocampus

Schneider, J., Berndt, N., Papageorgiou, I. E., Maurer, J., Bulik, S., Both, M., Draguhn, A., Holzhütter, H., & Kann, O. (2017) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x17740091 · Cited by 41

Metabolic flexibility ensures proper neuronal network function in moderate neuroinflammation

Chausse, B., Malorny, N., Lewen, A., Poschet, G., Berndt, N., & Kann, O. (2024) · Scientific Reports · doi:10.1038/s41598-024-64872-1 · Cited by 38

Miro1-dependent mitochondrial dynamics in parvalbumin interneurons

Kontou, G., Antonoudiou, P., Podpolny, M., Arancibia‐Cárcamo, I. L., Higgs, N., Szulc, B. R., López‐Doménech, G., Salinas, P. C., Mann, E. O., & Kittler, J. T. (2021) · eLife · doi:10.7554/elife.65215 · Cited by 37

Aging and Central Auditory Disinhibition: Is It a Reflection of Homeostatic Downregulation or Metabolic Vulnerability?

Ibrahim, B. A., & Llano, D. A. (2019) · Brain Sciences · doi:10.3390/brainsci9120351 · Cited by 34

The role of suboptimal mitochondrial function in vulnerability to post‐traumatic stress disorder

Preston, G., Kirdar, F., & Kozicz, T. (2018) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-018-0168-1 · Cited by 36

Long-Latency Reductions in Gamma Power Predict Hemodynamic Changes That Underlie the Negative BOLD Signal

Boorman, L. W., Harris, S., Bruyns‐Haylett, M., Kennerley, A. J., Zheng, Y., Martin, C. J., Jones, M., Redgrave, P., & Berwick, J. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.2339-14.2015 · Cited by 34

Coupling between gamma oscillation and fMRI signal in the rat somatosensory cortex: Its dependence on systemic physiological parameters

Sumiyoshi, A., Suzuki, H., Ogawa, T., Riera, J. J., Shimokawa, H., & Kawashima, R. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.12.082 · Cited by 37

Low neuronal metabolism during isoflurane-induced burst suppression is related to synaptic inhibition while neurovascular coupling and mitochondrial function remain intact

Berndt, N., Kovács, R., Schoknecht, K., Rösner, J., Reiffurth, C., Maechler, M., Holzhütter, H., Dreier, J. P., Spies, C., & Liotta, A. (2021) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x211010353 · Cited by 33

Tissue hypoxia correlates with intensity of interictal spikes

Geneslaw, A. S., Zhao, M., Ma, H., & Schwartz, T. H. (2011) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2011.16 · Cited by 34

Energy and Potassium Ion Homeostasis during Gamma Oscillations

Kann, O., Hollnagel, J., Elzoheiry, S., & Schneider, J. (2016) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2016.00047 · Cited by 34

Differences in Reperfusion-Induced Mitochondrial Oxidative Stress and Cell Death Between Hippocampal CA1 and CA3 Subfields Are Due to the Mitochondrial Thioredoxin System

Yin, B., Barrionuevo, G., Batinic̈‐Haberle, I., Sandberg, M., & Weber, S. G. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6706 · Cited by 34

Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients

Kallianpur, K. J., Gerschenson, M., Mitchell, B. I., Libutti, D. E., Umaki, T. M., Ndhlovu, L. C., Nakamoto, B. K., Chow, D. C., & Shikuma, C. M. (2016) · Mitochondrion · doi:10.1016/j.mito.2016.02.006 · Cited by 32

Dissecting the neuronal vulnerability underpinning Alpers’ syndrome: a clinical and neuropathological study

Hayhurst, H., Anagnostou, M., Bogle, H. J., Grady, J. P., Taylor, R. W., Bindoff, L. A., McFarland, R., Turnbull, D. M., & Lax, N. Z. (2018) · Brain Pathology · doi:10.1111/bpa.12640 · Cited by 29

Coupling between gamma-band power and cerebral blood volume during recurrent acute neocortical seizures

Harris, S., Ma, H., Zhao, M., Boorman, L. W., Zheng, Y., Kennerley, A. J., Bruyns‐Haylett, M., Overton, P. G., Berwick, J., & Schwartz, T. H. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.04.014 · Cited by 31

Epileptic Focus and Alteration of Metabolism

Otáhal, J., Folbergrová, J., Kovacs, R., Kunz, W. S., & Maggio, N. (2014) · International review of neurobiology · doi:10.1016/b978-0-12-418693-4.00009-1 · Cited by 29

Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein

Tweedy, C., Kindred, N., Curry, J., Williams, C., Taylor, J., Atkinson, P. J., Randall, F. E., Erskine, D., Morris, C. M., Reeve, A. K., et al. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.105226 · Cited by 26

How Energy Supports Our Brain to Yield Consciousness: Insights From Neuroimaging Based on the Neuroenergetics Hypothesis

Chen, Y., & Zhang, J. (2021) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2021.648860 · Cited by 39

The Neurometabolic Basis of Mood Instability: The Parvalbumin Interneuron Link—A Systematic Review and Meta-Analysis

Pinna, A., & Colasanti, A. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.689473 · Cited by 28

Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development

Wirtz, S., & Schuelke, M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018897 · Cited by 27

The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms

Orth, C. B., Schneider, J., Lewen, A., McQueen, J., Hasenpusch‐Theil, K., Theil, T., Hardingham, G. E., Bading, H., & Kann, O. (2019) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x19887777 · Cited by 26

Mild hypoxia-induced structural and functional changes of the hippocampal network

Hencz, A. J., Magony, A., Thomas, C. N., Kovacs, K., Szilagyi, G. T., Pál, J., & Attila Gabor, S. I. K. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1277375 · Cited by 27

Neuronal oscillations: A physiological correlate for targeting mitochondrial dysfunction in neurodegenerative diseases?

Chan, F., Lax, N. Z., Davies, C. H., Turnbull, D. M., & Cunningham, M. O. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.10.033 · Cited by 21

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