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The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300
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“E6 has also been shown to abrogate the transactivation of p53-responsive genes via interactions with CBP/p300, [181,182,183], with hADA3 [184,185,186], and by destabilizing TIP60 [185]”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [181]
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Citations
Cites
Phosphorylated CREB binds specifically to the nuclear protein CBP
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Nuclear protein CBP is a coactivator for the transcription factor CREB
Kwok, R. P. S., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bächinger, H. P., Brennan, R. G., Roberts, S. G. E., Green, M. R., & Goodman, R. H. (1994) · Nature · doi:10.1038/370223a0 · Cited by 1,443
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p300/MDM2 complexes participate in MDM2-mediated p53 degradation
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Suzuki, T., Fujisawa, J. I., Toita, M., & Yoshida, M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.2.610 · Cited by 256
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Metadata
- Authors
- Patel, D., Huang, S., Baglia, L. A., & McCance, D. J.
- Venue
- The EMBO Journal
- Published
- 1999-09-15
- Volume
- 18
- Issue
- 18
- Pages
- 5061-5072
- ISSN
- 0261-4189
- 1460-2075
- Cited by
- 374
- References
- 6
- Language
- en
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