BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

Miki, Y., Swensen, J. J., Shattuck-Eidens, D. M., Futreal, P. A., Harshman, K., Tavtigian, S. V., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., et al. (1994) · Science · doi:10.1126/science.7545954 · Cited by 6,069 · see citing works

Identification of the breast cancer susceptibility gene BRCA2

Wooster, R., Bignell, G. R., Lancaster, J., Swift, S., Seal, S., Mangion, J., Collins, N., Gregory, S. G., Gumbs, C. E., Micklem, G., et al. (1995) · Nature · doi:10.1038/378789a0 · Cited by 3,645 · see citing works

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

Hall, J., Lee, M. K., Newman, B. M., Morrow, J. E., Anderson, L. A., Huey, B., & King, M. (1990) · Science · doi:10.1126/science.2270482 · Cited by 2,544 · see citing works

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., & Bonner, W. M. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00610-2 · Cited by 2,098 · see citing works

Localization of a Breast Cancer Susceptibility Gene, BRCA2 , to Chromosome 13q12-13

Wooster, R., Neuhausen, S. L., Mangion, J., Quirk, Y., Ford, D., Collins, N., Nguyen, K. N., Seal, S., Tran, T. D., Averill, D., et al. (1994) · Science · doi:10.1126/science.8091231 · Cited by 1,918 · see citing works

Risks of cancer in BRCA1-mutation carriers

FORD, D. (1994) · The Lancet · doi:10.1016/s0140-6736(94)91578-4 · Cited by 1,850 · see citing works

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

Scully, R., Chen, J., Plug, A., Xiao, Y., Weaver, D., Feunteun, J., Ashley, T., & Livingston, D. M. (1997) · Cell · doi:10.1016/s0092-8674(00)81847-4 · Cited by 1,459 · see citing works

Cancer risks in BRCA2 mutation carriers.

Olsson, H. (1999) · Journal of the National Cancer Institute · doi:10.1093/jnci/91.15.1310 · Cited by 1,404 · see citing works

BRCA1 mutations in primary breast and ovarian carcinomas.

Futreal, P., Liu, Q., Shattuck-Eidens, D., Cochran, C., Harshman, K., Tavtigian, S., Bennett, L., Haugen-Strano, A., Swensen, J., & Miki, Y. (1994) · Science · doi:10.1126/science.7939630 · Cited by 1,378 · see citing works

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.

Wang, Y., Cortez, D., Yazdi, P., Neff, N., Elledge, S. J., & Qin, J. (2000) · Genes & Development · doi:10.1101/gad.14.8.927 · Cited by 1,221 · see citing works

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

Scully, R., Chen, J., Ochs, R. L., Keegan, K., Hoekstra, M., Feunteun, J., & Livingston, D. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80503-6 · Cited by 900 · see citing works

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation

Xu, X., Wagner, K., Larson, D. M., Ohler, Z. W., Li, C., Ried, T., Hennighausen, L. G., Wynshaw-Boris, A. J., & Deng, C. (1999) · Nature Genetics · doi:10.1038/8743 · Cited by 758 · see citing works

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

Wu, L. C., Wang, Z. W., Tsan, J. T., Spillman, M. A., Phung, A., Xu, X. L., Yang, M.-C. W., Hwang, L.-Y., Bowcock, A. M., & Baer, R. J. (1996) · Nature Genetics · doi:10.1038/ng1296-430 · Cited by 743 · see citing works

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

Jensen, D. E., Proctor, M. L., Marquis, S. T., Gardner, H. P., Ha, S. I., Chodosh, L. A., Ishov, A. M., Tommerup, N., Vissing, H., Sekido, Y., et al. (1998) · Oncogene · doi:10.1038/sj.onc.1201861 · Cited by 725 · see citing works

In search of the tumour-suppressor functions of BRCA1 and BRCA2

Scully, R., & Livingston, D. M. (2000) · Nature · doi:10.1038/35044000 · Cited by 643 · see citing works

Association of BRCA1 with the hRad50-hMre11-p95 Complex and the DNA Damage Response

Zhong, Q., Chen, C.-F., Li, S., Chen, Y., Wang, C.-C., Xiao, J., Chen, P.-L., Sharp, Z. D., & Lee, W.-H. (1999) · Science · doi:10.1126/science.285.5428.747 · Cited by 626 · see citing works

Human genome organization: Alu, LINES, and the molecular structure of metaphase chromosome bands

Korenberg, J. R., & Rykowski, M. C. (1988) · Cell · doi:10.1016/0092-8674(88)90159-6 · Cited by 560 · see citing works

Induction of GADD45 and JNK/SAPK-Dependent Apoptosis following Inducible Expression of BRCA1

Harkin, D. P., Bean, J. M., Miklos, D. B., Song, Y., Truong, V. B., Englert, C., Christians, F. C., Ellisen, L. W., Maheswaran, S., Oliner, J. D., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80769-2 · Cited by 558 · see citing works

An entire functional mammary gland may comprise the progeny from a single cell

Kordon, E. C., & Smith, G. H. (1998) · Development · doi:10.1242/dev.125.10.1921 · Cited by 553 · see citing works

BRCA1 Is Associated with a Human SWI/SNF-Related Complex

Bochar, D. A., Wang, L., Beniya, H., Kinev, A. V., Xue, Y., Lane, W. S., Wang, W., Kashanchi, F., & Shiekhattar, R. (2000) · Cell · doi:10.1016/s0092-8674(00)00030-1 · Cited by 546 · see citing works

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

Lee, J., Collins, K. M., Brown, A. L., Lee, C. H., & Chung, J. H. (2000) · Nature · doi:10.1038/35004614 · Cited by 529 · see citing works

BRCA1 inhibition of estrogen receptor signaling in transfected cells.

Fan, S., Wang, J.-A., Yuan, R., Ma, Y., Meng, Q., Erdos, M., Pestell, R., Yuan, F., Auborn, K., Goldberg, I., et al. (1999) · Science · doi:10.1126/science.284.5418.1354 · Cited by 521 · see citing works

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

Tibbetts, R. S., Cortez, D., Brumbaugh, K. M., Scully, R., Livingston, D., Elledge, S. J., & Abraham, R. T. (2000) · Genes & Development · doi:10.1101/gad.851000 · Cited by 512 · see citing works

BRCA1 physically associates with p53 and stimulates its transcriptional activity

Zhang, H., Somasundaram, K., Peng, Y., Tian, H., Zhang, H., Bi, D., Weber, B. L., & El‐Deiry, W. S. (1998) · Oncogene · doi:10.1038/sj.onc.1201932 · Cited by 492 · see citing works

BRCA1 is a component of the RNA polymerase II holoenzyme

Scully, R., Anderson, S. F., Chao, D. M., Wei, W., Ye, L., Young, R. A., Livingston, D. M., & Parvin, J. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.11.5605 · Cited by 454 · see citing works

Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas

Wilson, C., Ramos, L., Villaseñor, M. R., Anders, K. H., Press, M. F., Clarke, K., Karlan, B. Y., Chen, J.-J., Scully, R., Livingston, D. M., et al. (1999) · Nature Genetics · doi:10.1038/6029 · Cited by 414 · see citing works

Allele losses in the region 17q12–21 in familial breast and ovarian cancer involve the wild–type chromosome

Smith, S. A., Easton, D. F., Evans, D. G., & Ponder, B. A. J. (1992) · Nature Genetics · doi:10.1038/ng1092-128 · Cited by 410 · see citing works

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

Anderson, S. F., Schlegel, B. P., Nakajima, T., Wolpin, E. S., & Parvin, J. D. (1998) · Nature Genetics · doi:10.1038/930 · Cited by 393 · see citing works

The C-terminal (BRCT) Domains of BRCA1 Interact in Vivo with CtIP, a Protein Implicated in the CtBP Pathway of Transcriptional Repression

Yu, X., Wu, L. C., Bowcock, A. M., Aronheim, A., & Baer, R. J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.39.25388 · Cited by 389 · see citing works

BRCA1 regulates p53-dependent gene expression

Ouchi, T., Monteiro, Á. N. A., August, A., Aaronson, S. A., & Hanafusa, H. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.5.2302 · Cited by 375 · see citing works

Epidermal growth factor-induced nuclear factor κB activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells

Biswas, D. K., Cruz, A. P., Gansberger, E., & Pardee, A. B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.15.8542 · Cited by 353 · see citing works

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

Li, S., Ting, N. S. Y., Zheng, L., Chen, P., Ziv, Y., Shiloh, Y., Lee, E. Y.-H. P., & Lee, W. (2000) · Nature · doi:10.1038/35018134 · Cited by 336 · see citing works

Insights into the functions of BRCA1 and BRCA2

Welcsh, P. L., Owens, K. N., & King, M. (2000) · Trends in Genetics · doi:10.1016/s0168-9525(99)01930-7 · Cited by 335 · see citing works

BRCA1 interacts with components of the histone deacetylase complex

Yarden, R. I., & Brody, L. C. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.9.4983 · Cited by 328 · see citing works

BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study.

Baldwin, R. L., Nemeth, E., Tran, H., Shvartsman, H. S., Cass, I. A., Narod, S. A., & Karlan, B. Y. (2000) · PubMed · Cited by 324 · see citing works

BRCA1 is associated with the centrosome during mitosis

Hsu, L., & White, R. L. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.12983 · Cited by 312 · see citing works

Role of direct interaction in BRCA1 inhibition of estrogen receptor activity

Fan, S., Ma, Y.-X., Wang, C.-G., Yuan, R., Meng, Q., Wang, J.-A., Erdos, M., Goldberg, I., Webb, P., Kushner, P., et al. (2001) · Oncogene · doi:10.1038/sj.onc.1204073 · Cited by 293 · see citing works

Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1.Preprint

Smith, T., Lee, M. K., Szabo, C., Jerome, N., Mceuen, M., Taylor, M. P., Hood, L., & King, M. (1996) · Genome Research · doi:10.1101/gr.6.11.1029 · Cited by 291 · see citing works

Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.

Collins, N., McManus, R., Wooster, R., Mangion, J., Seal, S., Lakhani, S. R., Ormiston, W. J., Daly, P. A., Ford, D., & Easton, D. F. (1995) · PubMed · Cited by 243 · see citing works

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

Wang, Q., Zhang, H., Kajino, K., & Greene, M. I. (1998) · Oncogene · doi:10.1038/sj.onc.1202403 · Cited by 243 · see citing works

Sequence-Specific Transcriptional Corepressor Function for BRCA1 through a Novel Zinc Finger Protein, ZBRK1

Zheng, L., Pan, H., Li, S., Flesken‐Nikitin, A., Chen, P., Boyer, T., & Lee, W. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00075-7 · Cited by 232 · see citing works

CBP/p300 interact with and function as transcriptional coactivators of BRCA1

Pao, G. M., Janknecht, R., Ruffner, H., Hunter, T. R., & Verma, I. M. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1020 · Cited by 222 · see citing works

Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach

Beger, C., Pierce, L. N., Krüger, M., Marcusson, E. G., Robbins, J. M., Welcsh, P. L., Welch, P. J., Welte, K., King, M., Barber, J. R., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.1.130 · Cited by 219 · see citing works

Unexpected relationships between four large deletions in the human β-globin gene cluster

Vanin, E. F., Henthom, P. S., Kioussis, D., Grosveld, F. G., & Smithies, O. (1983) · Cell · doi:10.1016/0092-8674(83)90103-4 · Cited by 210 · see citing works

The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-α Subunit of the Nuclear Transport Signal Receptor

Chen, C., Li, S., Chen, Y., Chen, P., Sharp, Z. D., & Lee, W. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.51.32863 · Cited by 203 · see citing works

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes

Ouchi, T., Lee, S. W., Ouchi, M., Aaronson, S. A., & Horvath, C. M. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.080469697 · Cited by 202 · see citing works

Binding of CtIP to the BRCT Repeats of BRCA1 Involved in the Transcription Regulation of p21 Is Disrupted Upon DNA Damage

Li, S., Chen, P., Subramanian, T., Chinnadurai, G., Tomlinson, G. E., Osborne, C. K., Sharp, Z. D., & Lee, W. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.16.11334 · Cited by 192 · see citing works

Interaction between the Product of the Breast Cancer Susceptibility Gene BRCA2 and DSS1, a Protein Functionally Conserved from Yeast to Mammals

Marston, N. J., Richards, W. J., Hughes, D. A., Bertwistle, D., Marshall, C. J., & Ashworth, A. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.7.4633 · Cited by 186 · see citing works

Lessons learned from BRCA1 and BRCA2

Zheng, L., Li, S., Boyer, T., & Lee, W. (2000) · Oncogene · doi:10.1038/sj.onc.1203968 · Cited by 185 · see citing works

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

Chai, Y., Cui, J., Shao, N., Reddy, E. S. P., & Rao, V. N. (1999) · Oncogene · doi:10.1038/sj.onc.1202323 · Cited by 179 · see citing works

Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells.

Yeh, S., Hu, Y.-C., Rahman, M., Lin, H.-K., Hsu, C.-L., Ting, H., Kang, H.-Y., & Chang, C. (2000) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.190353897 · Cited by 169 · see citing works

BRCA2 in American families with four or more cases of breast or ovarian cancer: recurrent and novel mutations, variable expression, penetrance, and the possibility of families whose cancer is not attributable to BRCA1 or BRCA2.

Schubert, E. L., Lee, M. K., Mefford, H. C., ARGONZA, R. H., Morrow, J. E., Hull, J., Dann, J. L., & King, M. (1997) · PubMed · Cited by 166 · see citing works

Characterization of a carboxy-terminal BRCA1 interacting protein

Wong, A. K. C., Ormonde, P. A., Pero, R. S., Chen, Y., Lian, L., Salada, G. C., Berry, S., Lawrence, Q. A., Dayananth, P., Ha, P. C., et al. (1998) · Oncogene · doi:10.1038/sj.onc.1202150 · Cited by 162 · see citing works

BRCA1-associated growth arrest is RB-dependent

Aprelikova, O. N., Fang, B. S., Meissner, E. G., Cotter, S. E., Campbell, M., Kuthiala, A., Bessho, M., Jensen, R. A., & Liu, E. T. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.21.11866 · Cited by 158 · see citing works

Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation

Deng, C., & Scott, F. (2000) · Oncogene · doi:10.1038/sj.onc.1203269 · Cited by 158 · see citing works

Screening for Genomic Rearrangements in Families with Breast and Ovarian Cancer Identifies BRCA1 Mutations Previously Missed by Conformation-Sensitive Gel Electrophoresis or Sequencing

Unger, M. A., Nathanson, K. L., Calzone, K., Antin-Ozerkis, D. E., Shih, H. A., Martin, A., Lenoir, G., Mazoyer, S., & Weber, B. L. (2000) · The American Journal of Human Genetics · doi:10.1086/303076 · Cited by 157 · see citing works

Nuclear structure and the three‐dimensional organization of DNA

Getzenberg, R. H., Pienta, K. J., Ward, W. S., & Coffey, D. S. (1991) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240470402 · Cited by 152 · see citing works

A Human BRCA2 Complex Containing a Structural DNA Binding Component Influences Cell Cycle Progression

Marmorstein, L. Y., Kinev, A. V., Chan, G. K. T., Bochar, D. A., Beniya, H., Epstein, J. A., Yen, T. J., & Shiekhattar, R. (2001) · Cell · doi:10.1016/s0092-8674(01)00209-4 · Cited by 147 · see citing works

Characterization of the expression pattern of p63α and δnp63α in benign and malignant oral epithelial lesions

Nylander, K., Coates, P. J., & Hall, P. A. (2000) · International Journal of Cancer · doi:10.1002/1097-0215(20000801)87:3 · Cited by 142 · see citing works

BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

Wang, H., Shao, N., Ding, Q. M., Cui, J., Reddy, E. S. P., & Rao, V. N. (1997) · Oncogene · doi:10.1038/sj.onc.1201252 · Cited by 130 · see citing works

Regulation of BRCA1 Expression by the Rb-E2F Pathway

Wang, A., Schneider‐Broussard, R., Kumar, A. P., MacLeod, M. C., & Johnson, D. G. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.6.4532 · Cited by 122 · see citing works

Identification of a Novel Cytoplasmic Protein That Specifically Binds to Nuclear Localization Signal Motifs

Li, S., Ku, C.-Y., Farmer, A. A., Cong, Y.-S., Chen, C., & Lee, W. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.11.6183 · Cited by 121 · see citing works

BRCA1 Is Phosphorylated at Serine 1497 In Vivo at a Cyclin-Dependent Kinase 2 Phosphorylation Site

Ruffner, H., Jiang, W. B., Craig, A. G., Hunter, T. R., & Verma, I. M. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.7.4843 · Cited by 115 · see citing works

Environmental signals and cell fate specification in premigratory neural crest

Dorsky, R. I., Moon, R. T., & Raible, D. W. (2000) · BioEssays · doi:10.1002/1521-1878(200008)22:8 · Cited by 111 · see citing works

BRCA2 associates with acetyltransferase activity when bound to P/CAF

Fuks, F., Milner, J., & Kouzarides, T. (1998) · Oncogene · doi:10.1038/sj.onc.1202475 · Cited by 107 · see citing works

Tumor Suppressor p53 Is Required To Modulate BRCA1 Expression

Arizti, P., Li, F., Park, I., Yin, Y., Solomon, E., Ouchi, T., Aaronson, S. A., & Lee, S. W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.20.7450-7459.2000 · Cited by 102 · see citing works

Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers

Collins, N., Wooster, R., & Stratton, M. (1997) · British Journal of Cancer · doi:10.1038/bjc.1997.526 · Cited by 101 · see citing works

Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chromosome 13q12-q13

Cleton-Jansen, A. M., Collins, N., Lakhani, S. R., Weissenbach, J., Devilee, P., Cornelisse, C., & Stratton, M. (1995) · British Journal of Cancer · doi:10.1038/bjc.1995.493 · Cited by 98 · see citing works

MYB oncogene amplification in hereditary BRCA1 breast cancer.

Kauraniemi, P., Hedenfalk, I. A., Persson, K., Duggan, D. J., Tanner, M., Johannsson, O. T., Olsson, H. L., Trent, J. M., Isola, J. J., & Borg, Å. (2000) · PubMed · Cited by 94 · see citing works

A large deletion disrupts the exon 3 transcription activation domain of the BRCA2 gene in a breast/ovarian cancer family.

Nordling, M., Karlsson, P., Wahlström, J., Engwall, Y., Wallgren, A., & Martinsson, T. (1998) · PubMed · Cited by 93 · see citing works

BRCA1: exploring the links to transcription

Monteiro, Á. N. A. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01632-7 · Cited by 87 · see citing works

BRCA1 and cell signaling

Wang, Q., Zhang, H., Fishel, R. A., & Greene, M. I. (2000) · Oncogene · doi:10.1038/sj.onc.1203974 · Cited by 87 · see citing works

Overexpression of BRCA2 gene in sporadic breast tumours

Bièche, I., Noguès, C., & Lidereau, R. (1999) · Oncogene · doi:10.1038/sj.onc.1202903 · Cited by 77 · see citing works

VCP, a Weak ATPase Involved in Multiple Cellular Events, Interacts Physically with BRCA1 in the Nucleus of Living Cells

Zhang, H., Wang, Q., Kajino, K., & Greene, M. I. (2000) · DNA and Cell Biology · doi:10.1089/10445490050021168 · Cited by 74 · see citing works

Sequences Attaching Loops of Nuclear and Mitochondrial DNA to Underlying Structures in Human Cells: The Role of Transcription Units

Jackson, D. A., Bartlett, J., & Cook, P. R. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.7.1212 · Cited by 74 · see citing works

DNA loops: structural and functional properties of scaffold‐attached regions

Roberge, M., & Gasser, S. M. (1992) · Molecular Microbiology · doi:10.1111/j.1365-2958.1992.tb01485.x · Cited by 70 · see citing works

The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells

Budhram-Mahadeo, V. S., Ndisang, D., Ward, T., Weber, B. L., & Latchman, D. S. (1999) · Oncogene · doi:10.1038/sj.onc.1203072 · Cited by 69 · see citing works

DNA polymerase stalling, sister chromatid recombination and the BRCA genes

Scully, R., Puget, N., & Vlasáková, K. (2000) · Oncogene · doi:10.1038/sj.onc.1203971 · Cited by 68 · see citing works

The elusive nuclear matrix

Jack, R. S., & Eggert, H. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb17314.x · Cited by 67 · see citing works

BRCA1 Physically and Functionally Interacts with ATF1

Houvras, Y. J., Benezra, M., Zhang, H., Manfredi, J. J., Weber, B. L., & Licht, J. D. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002539200 · Cited by 66 · see citing works

BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10α in activated transcription

Schlegel, B. P., Green, V. J., Ladias, J. A. A., & Parvin, J. D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3148 · Cited by 63 · see citing works

The BRCT Regions of Tumor Suppressor BRCA1 and of XRCC1 Show DNA End Binding Activity with a Multimerizing Feature

Yamane, K., Katayama, E., & TSURUO, T. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3983 · Cited by 62 · see citing works

Induction of the BRCA2 Promoter by Nuclear Factor-κB

Wu, K., Jiang, S. W., Thangaraju, M., Wu, G., & Couch, F. J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004390200 · Cited by 54 · see citing works

The Functions of Breast Cancer Susceptibility Gene 1 (BRCA1) Product and Its Associated Proteins

Irminger‐Finger, I., Siegel, B., & Leung, W.-C. (1999) · Biological Chemistry · doi:10.1515/bc.1999.019 · Cited by 53 · see citing works

Low expression of bcl-2 in Brca1-associated breast cancers

Fréneaux, P., Stoppa‐Lyonnet, D., Mouret, E., Kambouchner, M., Nicolas, A., Sigal‐Zafrani, B., Vincent‐Salomon, A., Fourquet, A., Magdelénat, H., & Sastre‐Garau, X. (2000) · British Journal of Cancer · doi:10.1054/bjoc.2000.1438 · Cited by 51 · see citing works

GA-binding protein α/β is a critical regulator of the BRCA1 promoter

Atlas, E., Stramwasser, M., Whiskin, K., & Mueller, C. R. (2000) · Oncogene · doi:10.1038/sj.onc.1203516 · Cited by 51 · see citing works

Potential role of BRCA2 in a mitotic checkpoint after phosphorylation by hBUBR1.

Futamura, M., Arakawa, H., Matsuda, K., Katagiri, T., Saji, S., Miki, Y., & Nakamura, Y. (2000) · PubMed · Cited by 48 · see citing works

The frequency and distribution of sister chromatid exchanges in human chromosomes

Morgan, W. F., & Crossen, P. E. (1977) · Human Genetics · doi:10.1007/bf00402152 · Cited by 37 · see citing works

The BRCA2 activation domain associates with and is phosphorylated by a cellular protein kinase

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BRCA1-associated growth arrest is RB-dependent

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