The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Sick individuals and sick populations
Abstract
Rose G (Department of Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK). Sick individuals and sick populations. International Journal of Epidemiology 1985;14:32--38. Aetiology confronts two distinct issues: the determinants of individual cases, and the determinants of incidence rate. If exposure to a necessary agent is homogeneous within a population, then case/control and cohort methods will fail to detect it: they will only identify markers of susceptibility. The corresponding strategies in control are the 'high-risk' approach, which seeks to protect susceptible individuals, and the population approach, which seeks to control the causes of incidence. The two approaches are not usually in competition, but the prior concern should always be to discover and control the causes of incidence.
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“Even small reductions of population exposure to large risks will yield substantial health gains.194”
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Strategy of prevention: lessons from cardiovascular disease.
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Reid, D. D., Hamilton, P. J. S., KEEN, H., Brett, G. Z., Jarrett, R. J., & Rose, G. (1974) · The Lancet · doi:10.1016/s0140-6736(74)92783-4 · Cited by 343
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Serum lipid precursors of coronary heart disease
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Research works printed but not linked: 1
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“…action, we use the in fl uential framework of preventive medicine proposed by Rose, who argued that massively applying to the general population an intervention with small individual bene fi ts could be more effectiveinreducingthenumberofdiseasecasesthantargetingonlythoseathigh-riskofdisease 14,15 .”
Metadata
- Authors
- Rose, G.
- Affiliations
- London School of Hygiene & Tropical Medicine (GB)
- Corresponding author
- Rose, Geoffrey
- Venue
- International Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-06
- Volume
- 30
- Issue
- 3
- Pages
- 427-432
- ISSN
- 0300-5771 (ISSN-L)
- 1464-3685
- OpenAlex
- W1907953089
- Cited by
- 3,736
- References
- 7
- Citations by year
- 2026: 84 · 2025: 108 · 2024: 113 · 2023: 157 · 2022: 137 · 2021: 184 · 2020: 168 · 2019: 182 · 2018: 162 · 2017: 153 · 2016: 154 · 2015: 192 · 2014: 184 · 2013: 174 · 2012: 177
- FWCI
- 374.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (submittedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Historical and modern epidemiology studies
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Keywords
- etiology, incidence rates, case-control study, cohort studies, susceptibility markers, high-risk approach, population approach, disease control
- MeSH terms
- Cardiovascular Diseases, Disease Susceptibility, Epidemiologic Methods, Humans, Population Surveillance, Risk, Causality, Incidence
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