Cited by 330Muscle metabolism and nutritionDiet and metabolism studiesCardiovascular and exercise physiology

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Dietary Protein and Exercise Have Additive Effects on Body Composition during Weight Loss in Adult Women

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Layman, Donald K., Evans, Ellen, Baum, Jamie I., Seyler, Jennifer, Erickson, Donna J., Boileau, Richard A.·2005·The Journal of Nutrition

DOI 10.1093/jn/135.8.1903

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Abstract

This study examined the interaction of 2 diets (high protein, reduced carbohydrates vs. low protein, high carbohydrates) with exercise on body composition and blood lipids in women (n = 48, approximately 46 y old, BMI = 33 kg/m(2)) during weight loss. The study was a 4-mo weight loss trial using a 2 x 2 block design (Diet x Exercise). Diets were equal in total energy (7.1 MJ/d) and lipids ( approximately 30% energy intake) but differed in protein content and the ratio of carbohydrate:protein at 1.6 g/(kg . d) and <1.5 (PRO group) vs. 0.8 g/(kg . d) and >3.5 (CHO group), respectively. Exercise comparisons were lifestyle activity (control) vs. a supervised exercise program (EX: 5 d/wk walking and 2 d/wk resistance training). Subjects in the PRO and PRO + EX groups lost more total weight and fat mass and tended to lose less lean mass (P = 0.10) than the CHO and CHO + EX groups. Exercise increased loss of body fat and preserved lean mass. The combined effects of diet and exercise were additive for improving body composition. Serum lipid profiles improved in all groups, but changes varied among diet treatments. Subjects in the CHO groups had larger reductions in total cholesterol and LDL cholesterol, whereas subjects in the PRO groups had greater reductions in triacylglycerol and maintained higher concentrations of HDL cholesterol. This study demonstrated that a diet with higher protein and reduced carbohydrates combined with exercise additively improved body composition during weight loss, whereas the effects on blood lipids differed between diet treatments.

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Background
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Authors: Layman, D. K., Evans, E., Baum, J. I., Seyler, J., Erickson, D. J., & Boileau, R. A.
Affiliations: University of Illinois Urbana-Champaign (US)
Corresponding author: Layman, Donald K.
ORCID: Layman, Donald K.
Evans, Ellen
Baum, Jamie I.
Venue: The Journal of Nutrition
Publisher: Elsevier BV
Published: 2005-08
Volume: 135
Issue: 8
Pages: 1903-1910
ISSN: 0022-3166 (ISSN-L)
DOI: 10.1093/jn/135.8.1903
OpenAlex: W2165340329
Cited by: 330
References: 44
Citations by year: 2026: 5 · 2025: 4 · 2024: 9 · 2023: 7 · 2022: 9 · 2021: 5 · 2020: 17 · 2019: 9 · 2018: 15 · 2017: 15 · 2016: 19 · 2015: 26 · 2014: 25 · 2013: 20 · 2012: 25
FWCI: 6.25
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 6392 d)
Locations: Journal of Nutrition (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Keywords: dietary protein, physical activity, body composition, weight loss, high-protein diet, low-carbohydrate diet, fat mass, lean body mass, serum lipids, cholesterol, triglycerides, HDL cholesterol, resistance training, walking, women
MeSH terms: Adult, Body Composition, Energy Intake, Dietary Carbohydrates, Dietary Proteins, Female, Humans, Life Style, Middle Aged, Weight Loss, Exercise, Body Mass Index, Diet, Protein-Restricted

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Dietary Protein and Exercise Have Additive Effects on Body Composition during Weight Loss in Adult Women

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