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The psychological impact of COVID-19 on the mental health in the general population
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As a result of the emergence of coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the Chinese city of Wuhan, a situation of socio-economic crisis and profound psychological distress rapidly occurred worldwide. Various psychological problems and important consequences in terms of mental health including stress, anxiety, depression, frustration, uncertainty during COVID-19 outbreak emerged progressively. This work aimed to comprehensively review the current literature about the impact of COVID-19 infection on the mental health in the general population. The psychological impact of quarantine related to COVID-19 infection has been additionally documented together with the most relevant psychological reactions in the general population related to COVID-19 outbreak. The role of risk and protective factors against the potential to develop psychiatric disorders in vulnerable individuals has been addressed as well. The main implications of the present findings have been discussed.
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“Factors such as a previous psychiatric diagnosis, isolation, financial distress, hopelessness, loneliness and uncertainty due to COVID-19 outbreaks can also increase the risk of psychiatric conditions and suicide.(Killgore et al., 2020a; Serafini et al., 2020; Xin et al., 2020; Serafini et al., 2012)”
From Younger people are more vulnerable to stress, anxiety and depression during COVID-19 pandemic: a global cross-sectional survey (2021) · cites this paper as Serafini et al., 2020
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“In contrast, resilience and perception of social support can be protective against psychiatric disorders.(Serafini et al., 2020)”
From Younger people are more vulnerable to stress, anxiety and depression during COVID-19 pandemic: a global cross-sectional survey (2021) · cites this paper as Serafini et al., 2020
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“This has led to a steep reduction in social contact which is likely to have increased experiences of loneliness and may have increased psychological distress (Barari et al., 2020; Serafini et al., 2020; Liu et al., 2020; Ellis et al., 2020).”
From Loneliness, social relationships, and mental health in adolescents during the COVID-19 pandemic (2021) · cites this paper as Serafini et al., 2020
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“This is in accordance with a study in bipolar patients [22].”
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“Under this discrimination, COVID-19 survivors may develop postCOVID-19 depression syndrome, anxiety, and psychosocial conflicts (Serafini et al., 2020).”
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“삶에 변화가 발생하여 적응이 필요한 상황에서 보호요인으로 작용하며, 이때 지각된 사회적 지지는 심리적 고통과 정신 병리 의 감소와 상관이 있는 것으로 알려져 있는데[12], 코로나19에”
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“The introduced restrictions, as well as fear for health, caused people to experience negative emotions, stress, depression and feelings of helplessness (Serafini et al. 2020).”
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“98,99 Unsurprisingly, several seminal COVID-19 publications have been cited at incredibly high rates as researchers have turned to these papers to help guide their next steps.”
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BackgroundOptimization of Students’ Performance Prediction through an Iterative Model of Frustration Severity
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STRESS, ANXIETY AND DEPRESSION AMONG RADIOGRAPHY STUDENTS DURING THE COVID-19 PANDEMIC
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Singh, A., & Gujral, H. K. (2022) · Journal of information and organizational sciences · doi:10.31341/jios.46.2.4 · Cited by 3
“A sudden lifestyle change has also increased psychological problems leading to alarming health and socio-economic crisis [7].”
Wang, J., Li, Y., Mu, Y., Huang, K., Li, D., Lan, C., Cui, Y., & Wang, J. (2024) · Science China Life Sciences · doi:10.1007/s11427-023-2488-0 · Cited by 3
“A reduction in social interactions between children, as a result of containment measures against COVID in many countries, was associated with an increase in psychological issues and arrested development in children (Giuntella et al., 2021; Serafini et al., 2020; World Health Organization, 2022).”
Uzer, T., Avşar, H., Tepegöz, H., & Kılıçkaya, S. T. (2024) · Memory · doi:10.1080/09658211.2024.2378873 · Cited by 3
“Moreover, educational and occupational systems have undergone substantial transformations in response to the challenges posed by the crisis (Sera fi ni et al., 2020).”
Coping, connection appraisal, and well-being during COVID-19 in the U.S., Japan, and Mexico
Benjamin, L. R., & Wang, S. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1420327 · Cited by 4
“…from earlier models based on previous global infections [e.g., Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS); Serafini et al., 2020] and use of prior psychological theories to predict COVID-19 outcomes and processes (e.g., Abrams et al., 2021; Pietromonaco…”
BackgroundBhuiyan, K. H., Kowser, A. M., & Deb, S. K. (2024) · Journal of Digital Marketing and Communication · doi:10.53623/jdmc.v4i2.494 · Cited by 3
“This study used convenient sampling techniques for data collection based on the characteristics of the population, whereas [39] stated that purposive sampling is appropriate for exploring behavioral patterns and mental health situations from an intuitive approach.”
Derakhshan, N., Jafari, Z., & Khalilian, P. (2025) · The Journal of General Psychology · doi:10.1080/00221309.2024.2449327 · Cited by 4
“While necessary measures like travel restrictions can control outbreaks, they can also worsen social and economic hardships (Akda � g et al., 2023; Mazrekaj & De Witte, 2024; Serafini et al., 2020).”
Crea, T. M., Klein, E. K., Okunoren, O., Collier, K. M., Currie, C., Smith, M., Sevalie, S., Molleh, B., Kabba, Y., Kargbo, A., et al. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e43040 · Cited by 3
The silent psychological impact of the COVID-19 pandemic in Sudan
Musa, H. H., Musa, T. H., Musa, I. H., Bingawi, H. M. E., Musa, I. H., & Campbell, M. C. (2020) · Ethics Medicine and Public Health · doi:10.1016/j.jemep.2020.100604 · Cited by 3
Psychological Impact: Unseen Effects of COVID-19
Alex, J., & Choudhary, G. N. (2021) · Indian Journal of Respiratory Care · doi:10.4103/ijrc.ijrc_137_20 · Cited by 3
Bejarano, D. P., Medina, D., Aluán, A., González, L., Cuenca, E., López, E., Enciso, A., Duarte, J., Arbo, G., Rolón, Á. R., et al. (2021) · Revista de salud publica del Paraguay · doi:10.18004/rspp.2021.junio.41 · Cited by 4
Saeedi, R., Rezaeimanesh, N., Sahraian, M. A., & Moghadasi, A. N. (2021) · Iranian Journal of Psychiatry · doi:10.18502/ijps.v16i3.6260 · Cited by 3
Almeida, C., Fernandes, J., & Mendes, F. (2021) · Jornal de Investigação Médica · doi:10.29073/jim.v2i2.427 · Cited by 3
Vitale, E., & Canonico, A. (2021) · Italian Journal of Gynaecology and Obstetrics · doi:10.36129/jog.33.03.07 · Cited by 3
“In this scenario literature is unable to define the risk and the lethality index in Covid-19 general population (4), specifically in pregnant women (5).”
BackgroundFactors Predisposing to Weight Gain in Young Adults during COVID-19 Home Confinement
Stănilă, A. M., Oravițan, M., Matichescu, M. L., Stănilă, C. V., Avram, A. C., Almăjan-Guţă, B., & Avram, C. (2021) · Timisoara Physical Education and Rehabilitation Journal · doi:10.2478/tperj-2021-0002 · Cited by 3
Psychological aspect of common people during lockdown
Chaklader, B., Srivastava, K., Rathod, H. K., & Ak, B. (2021) · Industrial Psychiatry Journal · doi:10.4103/0972-6748.328789 · Cited by 3
“[15] Another review article assessed the psychological impact of quarantine, reported insomnia, exhaustion, anxiety, and irritability as few common symptoms.[16] Sleep changes were observed during the COVID-19 lockdown.”
BackgroundPopulation Stress Reactions in North-East Hungary during the Pandemic
Rucska, A., & Lakatos, C. (2021) · European Journal of Marketing and Economics · doi:10.26417/723yca65o · Cited by 3
“In the last year, several studies and statements have dealt with the effects of COVID-19 on the physical (Cao & Li, 2020, Lvov et al., 2020) and mental well-being (Brooks et al., 2020, Pfefferbaum & North, 2020, Serafini et al., 2020).”
BackgroundThe Impact of COVID-19 Incidence on Motivation to Participate in a Triathlon
Poczta, J., Almeida, N. M. C., Paczyńska-Jędrycka, M., & Kruszyńska, E. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19095576 · Cited by 3
Bennett, B., Cosh, S., Thepsourinthone, J., & Lykins, A. D. (2022) · People and Animals The International Journal of Research and Practice · doi:10.62845/bieqr9x · Cited by 3
“…specifically), and need for power and control (Alleyne & Parfitt, 2019; Hensley & Tallichet, 2005; Parfitt & Alleyne, 2018a; van Wijk et al., 2017)—may all have increased because of the pandemic (e.g., Serafini et al., 2020; Smith et al., 2021), likely placing animals at higher risk of abuse.”
Emerging Challenges in COVID-19 With Substance Use Disorders
Salahuddin, M., Manzar, M. D., Pandi-Perumal, S. R., & BaHammam, A. S. (2021) · Addictive Disorders & Their Treatment · doi:10.1097/adt.0000000000000266 · Cited by 3
Eşkut, N., Ataç, C., Köşkderelioğlu, A., & Ünsal, Y. Ö. (2021) · OSMANGAZİ JOURNAL OF MEDICINE · doi:10.20515/otd.948805 · Cited by 3
Faizah, I., Kartini, Y., Sari, R. Y., Rohmawati, R., Afiyah, R. K., & Rahman, F. S. (2021) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2021.7216 · Cited by 3
“Social support can reduce various forms of stress, improve coping mechanisms and improve quality of life [26].”
BackgroundNarrating care during the COVID-19 pandemic in a paediatric emergency department
Vito, B. D., Castagno, E., Garrone, E., Tardivo, I., Conti, A., Luciani, M., Urbino, A., Garrino, L., & Dimonte, V. (2021) · Reflective Practice · doi:10.1080/14623943.2021.2013190 · Cited by 3
“Social support at work and family support seemed to have a key role, in line with reported strategies to prevent negative mental health outcomes during lockdowns (Serafini et al., 2020).”
ResultPsychological Distress among University Students
(2021) · Frontiers research topics · doi:10.3389/978-2-88966-770-3 · Cited by 3
Oncofertility and COVID-19: At the Crossroads between Two Time-Sensitive Fields
Varlas, V. N., Roxana Georgiana, B. O. R. S., Pop, A. L., Năsui, B. A., Bacalbaşa, N., Bohîlțea, R. E., Vlădăreanu, R., & Manolea, C. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11051221 · Cited by 3
“All these feelings can impair cognitive function and decision-making [93,94].”
BackgroundAhmad, T., Murtaza, B. N., Ahmad, F., Murad, M. A., Baig, M., Imtiaz, A., Baig, F., Baig, J., Siraj, M., & Sagga, A. K. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.768812 · Cited by 3
E-Learning Process in Elementry School: Bibliometrics Approach
Elihami, E. (2022) · Mahaguru Jurnal Pendidikan Guru Sekolah Dasar · doi:10.33487/mgr.v3i1.3102 · Cited by 3
Kleanthous, E., Evangelou, E., Georgiadou, A., Galanis, P., Andreadaki, E., Tzavara, C., Καϊτελίδου, Δ., & Kallergis, G. (2022) · European Journal of Trauma & Dissociation · doi:10.1016/j.ejtd.2022.100306 · Cited by 3
“One other study concluded that poor or inadequate information from public health authorities may be a significant stressor because it provides inappropriate guidelines concerning call for actions or leads to confusion (Serafini et al., 2020).”
Prevention of Mental Health Disorder among Adolescents during The COVID-19 Pandemic
Khariri, A., Mahendra, A. I., Maesarah, Augustria, N. R., Heru, R. A. S., & Zahra, Z. (2022) · Jurnal Psikiatri Surabaya · doi:10.20473/jps.v11i2.29688 · Cited by 4
Public Responses to the Novel 2019 Coronavirus (COVID-19) in China: Mental Health Consequences
Wang, J.-L., Zheng, X., Lan, Y., Zhang, X., Xu, Y., & Shen, J. (2020) · Journal of Emergency Management and Disaster Communications · doi:10.1142/s2689980920400011 · Cited by 2
MENTAL HEALTH: ESSENCE, MAIN DETERMINANTS, STRATEGIES AND PROGRAMS
Карамушка, Л. М. (2021) · PSYCHOLOGICAL JOURNAL · doi:10.31108/1.2021.7.5.3 · Cited by 3
Mental Health and Economic Concerns from March to May during the COVID-19 Pandemic in CanadaPreprint
Zajacova, A., Jehn, A., Stackhouse, M., Choi, K. H., Denice, P. A., Haan, M., & Ramos, H. (2020) · doi:10.31235/osf.io/76me2 · Cited by 3
Sood, S., & Sharma, A. (2020) · doi:10.21203/rs.3.rs-100641/v1 · Cited by 4
“Sera ni, G., Parmigiani, B., Amerio, A., Aguglia, A., Sher, L., & Amore, M. (2020).”
BackgroundResultInfluential
Metadata
- Authors
- Serafini, G., Parmigiani, B., Amerio, A., Aguglia, A., Sher, L., & Amore, M.
- Affiliations
- Ospedale Policlinico San Martino (IT)
- James J. Peters VA Medical Center (US)
- Corresponding author
- Serafini, G
- Venue
- QJM: An International Journal of Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-06-30
- Volume
- 113
- Issue
- 8
- Pages
- 531-537
- ISSN
- 0033-5622 (ISSN-L)
- 1460-2725
- 1460-2393
- PMC
- PMC7337855
- OpenAlex
- W3036526826
- Cited by
- 1,187
- References
- 40
- Citations by year
- 2026: 19 · 2025: 61 · 2024: 117 · 2023: 208 · 2022: 312 · 2021: 390 · 2020: 77
- FWCI
- 98.92
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- QJM (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- CINECA IRIS Institutial Research Information System (University of Genoa) (submittedVersion)
- Funders
- DINOGMI Department of Excellence of MIUR (2018-2022, 232/2016)
- Topics
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- COVID-19 pandemic, mental health, psychological distress, anxiety, depression, stress, uncertainty, quarantine, risk factors, protective factors, mental illness, general population
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