Cited by 313Migration, Health and TraumaSchizophrenia research and treatmentRacial and Ethnic Identity Research

Migration, Ethnicity, and Psychosis: Toward a Sociodevelopmental Model

Open access
Morgan, C., Charalambides, M., Hutchinson, G., Murray, R. M.·2010·Schizophrenia Bulletin

Abstract

There is consistent and strong evidence that the incidence of all psychoses is higher in many migrant and minority ethnic populations in a number of countries. The reasons for this are, however, unclear and a wide range of explanations have been proposed, from genetic to neurodevelopmental to psychosocial. In this article, we describe and evaluate the available evidence for and against each of these. What this shows is that: (1) there are few studies that have directly investigated specific risk factors in migrant and minority ethnic populations, with often only 1 or 2 studies of any relevance to specific explanations and (2) what limited research there has been tends to implicate a diverse range of social factors (including childhood separation from parents, discrimination and, at an area level, ethnic density) as being of potential importance. In an attempt to synthesize these disparate findings and provide a basis for future research, we go on to propose an integrated model--of a sociodevelopmental pathway to psychosis--to account for the reported high rates in migrant and minority ethnic populations. Aspects of this model will be directly tested in a new Europe-wide incidence and case-control study that we will conduct over the next 3 years, as part of the European Network of National Schizophrenia Networks studying Gene-Environment Interactions programme.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/schbul/sbq051

Cites

8 of 8 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Childhood adversity, and interpersonal trauma specifically, have been linked to the development of PEs, and there is evidence linking current adverse environments - characterized by racial discrimination, migrant status and low social capital - with psychosis.

    “Childhood adversity 25,26 , and interpersonal trauma specifically 27 , have been linked to the development of PEs, and there is evidence linking current adverse environments -characterized by racial discrimination 28 , migrant status 29 and low social capital 30 -with psychosis.”
  • Ethnic minority status can increase the risk of psychopathology through social isolation, experiences of discrimination, victimisation and social defeat, which are all considered stressors.

    “It is also likely that ethnic minority status can increase the risk of psychopathology through social isolation, experiences of discrimination, victimisation and social defeat, which are all considered stressors (Morgan et al., 2010; Bécares et al., 2009; Cooper et al., 2008; Cooper et al., 2017; Selten and Cantor-Graae, 2005; Selten et al., 2012; Sharpley et al., 2001; Tidey and Miczek, 1996).”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 85

  1. Cantor-Graae E, Selten JP. Schizophrenia and migration: a meta-analysis and review. Am J Psychiatry. 2005;162:12-24.
  2. Fearon P, Morgan C. Environmental factors in schizophre- nia: the role of migrant studies. Schizophr Bull. 2006;32: 405-408.
  3. Fearon P, Kirkbride JB, Morgan C, et al. Incidence of schizo- phrenia and other psychoses in ethnic minority groups: results from the MRC ÆSOP study. Psychol Med. 2006;36:1541- 1550.
  4. Bresnahan M, Begg MD, Brown A, et al. Race and risk of schizophrenia in a US birth cohort: another example of health disparity? Int J Epidemiol. 2007;36:751-758.
  5. Cantor-Graae E, Zolkowska K, McNeil TF. Increased risk of psychotic disorder among immigrants in Malmo: a 3-year first-contact study. Psychol Med. 2005;35:1155-1163.
  6. Selten JP, Slaets JP, Kahn RS. Schizophrenia in Surinamese and Dutch Antillean immigrants to The Netherlands: evidence of an increased incidence. Psychol Med. 1997;27:807-811.
  7. McKenzie K, Fearon P, Hutchinson G. Migration, ethnicity and psychosis. In: Morgan C, McKenzie K, Fearon P, eds. Society and Psychosis. Cambridge, UK: Cambridge Univer- sity Press; 2008:143-160.
  8. EU-GEI.Schizophrenia aetiology: do gene-environment inter- actions hold the key? Schizophr Res. 2008;102(1-3):21-26.
  9. Morgan C, Hutchinson G. The social determinants of psy- chosis in migrant and ethnic minority populations: a public health tragedy. Psychol Med. 2010;40:705-709.
  10. Hutchinson G, Haasen C. Migration and schizophrenia: the challenges for European psychiatry and implications for the future. Soc Psychiatry Psychiatr Epidemiol. 2004;39:350-357.
  11. Ødegaard Ø. Emigration and Insanity. Acta Psychiatr Neurol Scand Suppl. 1932;4:1-206.
  12. Fernando S. Mental Health, Race and Culture. London, UK: Palgrave Macmillan; 1991.
  13. Patel K, Hegginbotham C. Institutional racism in psychiatry does not imply racism in individual psychiatrists: commen- tary on . Institutional racism in psychiatry. Psychiatr Bull. 2007;31:367-368.
  14. Williams DR, Earl TR. Commentary: race and mental health-more questions than answers. Int J Epidemiol. 2007; 36:758-760.
  15. Selten JP, Cantor-Graae E. The denial of a psychosis epi- demic. Psychol Med. 2009;40:731-733.
  16. Hickling FW, McKenzie K, Mullen R, Murray RA. Jamaican psychiatrist evaluates diagnoses at a London psychiatric hos- pital. Br J Psychiatry. 1999;175:283-285.
  17. Lewis G, David A. Racism and psychiatry. Br J Psychiatry. 1991;158:432-433.
  18. Minnis H, McMillan A, Gillies M, Smith S. Racial stereotyp- ing: survey of psychiatrists in the United Kingdom. BMJ. 2001;323:905-906.
  19. Morgan C, Fisher H, Hutchinson G, et al. Ethnicity, social disadvantage and psychotic-like experiences in a healthy pop- ulation based sample. Acta Psychiatr Scand. 2009;119:226- 235.
  20. Johns LC, Cannon M, Singleton N, et al. Prevalence and cor- relates of self-reported psychotic symptoms in the British population. Br J Psychiatry. 2004;185:298-305.
  21. Johns L, Nazroo J, Bebbington P, Kuipers E. Occurrence of hallucinatory experiences in a community sample and ethnic variations. Br J Psychiatry. 2002;180:174-178.
  22. Kirkbride JB, Barker D, Cowden F, et al. Psychoses, ethnicity and socio-economic status. Br J Psychiatry. 2008;193(1):18- 24.
  23. King M, Coker E, Leavey G, Hoare A, Sabine-Johnson E. In- cidence of psychotic illness in London: comparison of ethnic groups. Br Med J. 1994;309:1115-1119.
  24. Hutchinson G, Takei N, Sham P, Harvey I, Murray RM. Factor analysis of symptoms in schizophrenia: differences be- tween White and Caribbean patients in Camberwell. Psychol Med. 1999;29:607-612.
  25. Demjaha A, Morgan K, Morgan C, et al. Symptom dimen- sions and ethnicity in the ÆSOP first onset psychosis study. Schizophr Res. 2006;81:233-233.
  26. Ndetei DM, Vadher A. A comparative cross-cultural study of the frequencies of hallucination in schizophrenia. Acta Psy- chiatr Scand. 1984;70:545-549.
  27. Selten JP, Cantor-Graae E, Slaets J, Kahn RS. Ødegaard's se- lection hypothesis revisited: schizophrenia in Surinamese immigrants to the Netherlands. Am J Psychiatry. 2002;159: 669-671.
  28. Lundberg P, Cantor-Graae E, Kahima M, Ostergren PO. De- lusional ideation and manic symptoms in potential future emigrants in Uganda. Psychol Med. 2007;37:505-512.
  29. Harrison G, Owens D, Holton A, Neilson D, Boot D. A pro- spective study of severe mental disorder in Afro-Caribbean patients. Psychol Med. 1988;18:643-657.
  30. Sugarman PA, Craufurd D. Schizophrenia in the Afro- Caribbean community. Br J Psychiatry. 1994;164:474-480.
  31. Hutchinson G, Takei N, Fahy TA, et al. Morbid risk of schizophrenia in first-degree relatives of white and African- Caribbean patients with psychosis. Br J Psychiatry. 1996;169:776-780.
  32. Selten JP, Blom JD, Van der Tweel I, Veiling W, Leliefeld B, Hoek HW. Psychosis risk for parents and siblings of Dutch and Moroccan-Dutch patients with non-affective psychotic disorder. Schizophr Res. 2008;104:274-278.
  33. Hickling F, Rodgers-Johnson P. The incidence of first-con- tact schizophrenia in Jamaica. Br J Psychiatry. 1995;167:193-196.
  34. Bhugra D, Hilwig M, Hossein B, et al. First-contact incidence rates of schizophrenia in Trinidad and one-year follow-up. Br J Psychiatry. 1996;169:587-592.
  35. Mahy G, Mallett R, Leff J, Bhugra D. First-contact incidence rate of schizophrenia in Barbados. Br J Psychiatry. 1999;175:28-33.
  36. Eagles JM. The relationship between schizophrenia and im- migration. Are there alternatives to psychosocial hypotheses? Br J Psychiatry. 1991;159:783-789.
  37. Brown AS. Prenatal infection as a risk factor for schizophre- nia. Schizophr Bull. 2006;32(2):200-202.
  38. Parsons CG. West Indian Babies with Multiple Congenital Defects. Arch Dis Child. 1963;38:454-458.
  39. Gomwalk NE, Ahmad AA. Prevalence of rubella antibodies on the African continent. Rev Infect Dis. 1989;11(1):116-121.
  40. Clarke MC, Harley M, Cannon M. The role of obstetric events in schizophrenia. Schizophr Bull. 2006;32(1):3-8.
  41. McKenzie K, Murray R. Risk factors for psychosis in the UK African-Caribbean population. In: Bhugra D, Bahl V, eds. Ethnicity: An Agenda for Mental Health. London, UK: Gas- kel; 1999:48-59.
  42. Harvey I, Williams M, McGuffin P, Toone BK. The func- tional psychoses in Afro-Caribbeans. Br J Psychiatry. 1990;157:515-522.
  43. Hutchinson G, Takei N, Bhugra D, et al. Increased rate of psychosis among African-Caribbeans in Britain is not due to an excess of pregnancy and birth complications. Br J Psy- chiatry. 1997;171:145-147.
  44. McGrath J. Hypothesis: is low prenatal vitamin D a risk- modifying factor for schizophrenia? Schizophr Res. 1999;40(3):173-177.
  45. Morgan C, Dazzan P, Morgan K, et al. First episode psycho- sis and ethnicity: initial findings from the ÆSOP study. World Psychiatry. 2006;5(1):40-46.
  46. Dean K, Dazzan P, Lloyd T, et al. Minor physical anomalies across ethnic groups in a first episode psychosis sample. Schizophr Res. 2007;89(1-3):86-90.
  47. Dazzan P, Lloyd T, Morgan KD, et al. Neurological abnor- malities and cognitive ability in first-episode psychosis. Br J Psychiatry. 2008;193(3):197-202.
  48. Moore TH, Zammit S, Lingford-Hughes A, et al. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet. 2007;370:319-328.
  49. McGuire PK, Jones P, Harvey I, Williams M, McGuffin P, Murray RM. Morbid risk of schizophrenia for relatives of patients with cannabis-associated psychosis. Schizophr Res. 1995;15:277-281.
  50. Cantwell R, Brewin J, Glazebrook C, et al. Prevalence of sub- stance misuse in first-episode psychosis. Br J Psychiatry. 1999;174:150-153.
  51. Hoare J. Drug Misuse Declared: Findings from the 2008/09 British Crime Survey. Home Office Statistical Bulletin 12/09. London, UK: Home Office; 2009.
  52. Hutchinson G, Murray R. Risk factors for first-episode schizophrenia in Trinidad and Tobago. Schizophr Res. 2006;81:238.
  53. Bhugra D, Jones P. Migration and mental illness. Adv Psychi- atric Treat. 2001;7:216-223.
  54. Hemsi LK. Psychotic morbidity of West Indian immigrants. Soc Psychiatry. 1967;2:95-100.
  55. Mallett R, Leff J, Bhugra D, Pang D, Zhao JH. Social envi- ronment, ethnicity and schizophrenia. Soc Psychiatry Psy- chiatr Epidemiol. 2002;37:329-335.
  56. Morgan C, Kirkbride J, Leff J, et al. Parental separation, loss and psychosis in different ethnic groups: a case-control study. Psychol Med. 2007;37:495-503.
  57. Morgan C, Kirkbride J, Hutchinson G, et al. Cumula- tive social disadvantage, ethnicity and first-episode psy- chosis: a case-control study. Psychol Med. 2008;38:1701- 1715.
  58. Karlsen S, Nazroo JY. Relation between racial discrimina- tion, social class, and health among ethnic minority groups. Am J Public Health. 2002;92:624-631.
  59. Gilvarry CM, Walsh E, Samele C, et al. Life events, ethnicity and perceptions of discrimination in patients with severe men- tal illness. Soc Psychiatry Psychiatr Epidemiol. 1999;34:600- 608.
  60. Cooper C, Morgan C, Byrne M, et al. Perceptions of disad- vantage, ethnicity and psychosis: results from the ÆSOP study. Br J Psychiatry. 2008;192:185-190.
  61. Veling W, Hoek HW, Mackenbach JP. Perceived discrimina- tion and the risk of schizophrenia in ethnic minorities: a case- control study. Soc Psychiatry Psychiatr Epidemiol. 2008;43: 953-959.
  62. March D, Hatch SL, Morgan C, et al. Psychosis and place. Epidemiol Rev. 2008;30:84-100.
  63. March D, Morgan C, Bresnahan M, Susser E. Conceptualis- ing the social world. In: Morgan C, McKenzie K, Fearon P, eds. Society and Psychosis. Cambridge, UK: Cambridge Uni- versity Press; 2008:41-57.
  64. Faris R, Dunham H. Mental Disorders in Urban Areas. Chi- cago: University of Chicago Press; 1939.
  65. Boydell J, van Os J, McKenzie K, et al. Incidence of schizo- phrenia in ethnic minorities in London: ecological study into interactions with environment. Br Med J. 2001;323:1336-1338.
  66. Kirkbride JB, Morgan C, Fearon P, Dazzan P, Murray RM, Jones PB. Neighbourhood-level effects on psychoses: re- examining the role of context. Psychol Med. 2007;37:1413-1425.
  67. Veling W, Susser E, van Os J, Mackenbach JP, Selten JP, Hoek HW. Ethnic density of neighborhoods and incidence of psychotic disorders among immigrants. Am J Psychiatry. 2008;165(1):66-73.
  68. Morgan C, Hutchinson G. The sociodevelopmental origins of psychosis. In: Morgan C, Bhugra D, eds. Principles of Social Psychiatry. 2nd ed Oxford, UK: Wiley-Blackwell; 2010:193-214.
  69. Krabbendam L, van Os J. Schizophrenia and urbanicity: a major environmental influence-conditional on genetic risk. Schizophr Bull. 2005;31:795-799.
  70. Pedersen CB, Mortensen PB. Evidence of a dose-response re- lationship between urbanicity during upbringing and schizo- phrenia risk. Arch Gen Psychiatry. 2001;58:1039-1046.
  71. Kirkbride JB, Fearon P, Morgan C, et al. Heterogeneity in in- cidence rates of schizophrenia and other psychotic syn- dromes: findings from the 3-center ÆSOP study. Arch Gen Psychiatry. 2006;63:250-258.
  72. Morgan C, McKenzie K, Fearon P. Society and Psychosis. Cambridge, UK: Cambridge University Press; 2008.
  73. Morgan C, Fisher H. Environment and schizophrenia: envi- ronmental factors in schizophrenia: childhood trauma-a critical review. Schizophr Bull. 2007;33(1):3-10.
  74. van Os J, Rutten BP, Poulton R. Gene-environment interac- tions in schizophrenia: review of epidemiological findings and future directions. Schizophr Bull. 2008;34:1066-1082.
  75. Collip D, Myin-Germeys I, Van Os J. Does the concept of "sensitization" provide a plausible mechanism for the putative link between the environment and schizophrenia? Schizophr Bull. 2008;34:220-225.
  76. Howes OD, Kapur S. The dopamine hypothesis of schizo- phrenia: version III-the final common pathway. Schizophr Bull. 2009;35:549-562.
  77. Pariante CM, Vassilopoulou K, Velakoulis D, et al. Pituitary volume in psychosis. Br J Psychiatry. 2004;185:5-10.
  78. Garety PA, Bebbington P, Fowler D, Freeman D, Kuipers E. Implications for neurobiological research of cognitive models of psychosis: a theoretical paper. Psychol Med. 2007;37:1377- 1391.
  79. Selten JP, Cantor-Graae E. Social defeat: risk factor for schizophrenia? Br J Psychiatry. 2005;187:101-102.
  80. Freeman D, Garety PA, Kuipers E. Persecutory delusions: developing the understanding of belief maintenance and emotional distress. Psychol Med. 2001;31:1293-1306.
  81. Bentall RP, Fernyhough C. Social predictors of psychotic experiences: specificity and psychological mechanisms. Schiz- ophr Bull. 2008;34:1012-1020.
  82. Sharpley MS, Peters ER. Ethnicity, class and schizotypy. Soc Psychiatry Psychiatr Epidemiol. 1999;34:507-512.
  83. Bebbington P, Fowler D, Garety P, Freeman D, Kuipers E. Theories of cognition, emotion and the social world: missing links in psychosis. In: Morgan C, McKenzie K, Fearon P, eds. Society and Psychosis. Cambridge, UK: Cambridge Uni- versity Press; 2008:219-237.
  84. Myin-Germeys I, van Os J. Adult adversity: do early environ- ment and genotype create lasting vulnerability for adult social adversity in psychosis? In: Morgan C, McKenzie K, Fearon P, eds. Society and Psychosis. Cambridge, UK: Cambridge University Press; 2008:127-142.
  85. Keen DV, Reid FD, Arnone D. Autism, ethnicity and mater- nal immigration. Br J Psychiatry. 2010;196:274-281.

Cited by

Sorted by citations

Authors
Morgan, C., Charalambides, M., Hutchinson, G., & Murray, R. M.
Affiliations
  • King's College London (GB)
  • University of the West Indies (TT)
Corresponding author
Morgan, C.
Venue
Schizophrenia Bulletin
Published
2010-05-30
Volume
36
Issue
4
Pages
655-664
ISSN
  • 0586-7614 (ISSN-L)
  • 1745-1701
OpenAlex
W2159984117
Cited by
313
References
8
Citations by year
2026: 6 · 2025: 9 · 2024: 10 · 2023: 18 · 2022: 17 · 2021: 22 · 2020: 18 · 2019: 23 · 2018: 31 · 2017: 23 · 2016: 30 · 2015: 18 · 2014: 27 · 2013: 26 · 2012: 20
FWCI
21.14
Type
journal article
Language
en
Open access
Locations
  • Schizophrenia Bulletin (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Research Portal (King's College London) (submittedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Migration, Health and Trauma
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Sociology and Political Science › Racial and Ethnic Identity Research
Keywords
psychosis, schizophrenia
MeSH terms
Cross-Sectional Studies, Emigration and Immigration, Ethnicity, Europe, Humans, Life Change Events, Minority Groups, Models, Psychological, Prejudice, Psychotic Disorders, Risk Factors, Schizophrenia, Schizophrenic Psychology, Social Environment, Bias, Incidence, Case-Control Studies, Genetic Predisposition to Disease

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review